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ANALISIS KEPUASAN MAHASISWA TERHADAP KUALITAS PELAYANAN TENAGA ADMINISTRATIF DI FAKULTAS FARMASI UNIVERSITAS AHMAD DAHLAN YOGYAKARTA
Get PDFStudent satisfaction measurement has been done with populatif observation and data collectedprospectively at the fourth level students of the Faculty of Pharmacy Ahmad Dahlan University. Thepurpose this study to describe and determine student satisfaction ratings gap that arises from servqual.The results obtained indicate generally that the service element in the Faculty of Pharmacy is namelyemployees has not given in accordance with the expectations of student performance is characterizedby a range of values of each gap there is nothing close to the ideal of zero (0). Gap values ofemployees in the education ministry on Tangible dimensions with a gap value -0,90, Reliability withthe gap value -0,90, Assurance gap value -0,90, Empathy with the gap value -1,10 andResponsiveness to the value gap -1,10 . While the reliability of the employee dimension into the first rank and dimensions of responsiveness on the faculty is considered the most excellent service tostudents
EFEK HIPOGLIKEMIK EKSTRAK ETANOL UMBI KETELA RAMBAT (Ipomoea batatas P) (EEUKR) PADA MENCIT SWISS YANG DIINDUKSI ALOKSAN
Get PDFSweet potatos rood contain lots of beta-carotene, polyphenols and flavonoids. Alloxan provenpancreatic cell damage through oxidative stress mechanisms. The compound beta-carotene,polyphenols and flavonoids are thought to antioxidative and cytoprotective, inhibit cell damage causedby alloxan exposure. This study aimed to determine the effect of ethanolic extract of sweet potatos(Ipomoea batatas P) (EEUKR) on blood glucose levels and pancreatic histopathology on alloxaninducedSwiss mice. Used 15 test animals, Swiss mice, with an average weight of 20-30 grams. Testanimals were divided into 5 groups, with each group consisting of 3 mice. Group I was the negativecontrol group who were given distilled water (akua group), and group II, III, IV and V are thetreatment group were given ethanolic extract of sweet potatos rood (EEUKR) at a dose of 2.5, 7.5,22.5 and 67.5 mg/KgBW/day orally for 10 days, 7 days before and 3 days after the alloxan induced.Alloxan induction performed on the 7th day intraperitoneally at a dose of 120 mg/kgBW. Examinationof blood glucose levels conducted on 4th and day 10th day of treatment. On the 10th day of the testanimals were sacrificed for isolated pancreas and histopathologic examination. Analysis of varianceconducted to determine the significance difference in average blood glucose levels between groupsduring the test and ANOVA followed by LSD test at 95% confidence level. Pancreatic histopathologydata were analyzed qualitatively. The results showed that the EEUKR dose of 22.5 and 67.5mg/kgBW/day had the effect of hypoglycemia in Swiss mice. Blood glucose levels of Swiss micebefore alloxan induced in treatment group with EEUKR dose of 67,5 mg/Kg BW were lower thanblood glucose levels of akua groups, statistically significant (p <0,05). Blood glucose levels of alloxaninduced swiss mice of treatment groups with EEUKR dose of 22.5 and 67.5 mg/KgBW were lowerthan blood glucose level of akua group and statistically significant (p <0.05). The percentage ofpancreatic necrosis of alloxan-induced Swiss mice of treatment groups with EEUKR dose of 22.5 and67.5 mg/kg BW were lower than the percentage of necrosis of akua group. Based on these results itcan be concluded that the EEUKR doses of 22.5 and 67.5 mg/KgBW are found to be hypoglycemic inSwiss mice both before and after alloxan induced. The EEUR also shown to decrease the incidence ofpancreatic necrosis in alloxan-induced Swiss mice
DIMETILSULFOKSID SEBAGAI ENHANCER TRANSPOR TRANSDERMAL TEOFILIN SEDIAAN GEL
Get PDFDimethylsulfoxide (DMSO) has been intensively studied the 19th century. Thissubstance is used as a medicine and solve. It can also be used as an absorptionenhancer of various drugs, either synthetical or herbal medicines. This study conductedwith DMSO as transdermal absorption enhancer of theophylline, which often used asan anti-cellulite dosage forms. The experiments studied in vitro transdermalabsorption of theophylline in gel dosage forms, containing 7% theophylline danvarious concentration of DMSO i.e. 0% , 3%, 5% and 7% DMSO respectively. Thesestudies used skin membrane of Wistar strain male rats in a vertical type diffusion Cell.The results indicated that DMSO was very potential as a permeation enhancertheophylline, the formula containing 7% DMSO increased the theophylline transportfrom 17,9 µg to 139,1 µg
PENETAPAN KADAR ß-KAROTEN PADA BEBERAPA JENIS CABE (Genus Capsicum) DENGAN METODE SPEKTROFOTOMETRI TAMPAK
No full textBeta carotene is provitamin essential role for vitamin A formation. Most of vitamin Asources are ß-carotene. In the body, ß-carotene will be converted into vitamin A. Chilies areconsidered as one of the essential food. Chillies are known as very good sources of ß-carotene.Therefore, it is important to conduct a research in order to observe the content of ß-carotene inthe chillies using visible spectrophotometry. Fresh chillies were extracted with a mixture ofhexane:acetone:ethanol (2:1:1) v/v using a maceration method. After the extraction process wascomplete, aquabidest was added. The extraction result was non-polar phase. It was separatedand evaporated. The residue was further subjected to qualitative and quantitative analysis102 Pharmaҫiana, Vol. 4, No. 2, 2014: 101-109obtained. Qualitative analysis by using Carr-Price method. Determination of ß-carotene wasconducted using visible spectrophotometry method at 452,4 nm. The qualitative test resultsshowed that the Capsicum annuum L. Var. abreviatum Fingerhuth, Capsicum annuum L. Var.Longum sendt) and Capsicum frutescens L. contain ß-carotene. From the research, it wasobtained that the average levels of ß-carotene on the Capsicum annuum L. Var. abreviatumFingerhuth was (10,54±0,07) mg/100g, Capsicum annuum L. Var. Longum sendt was(5,57±0,13) mg/100g and Capsicum frutescens L. was about (0,36±0,01) mg/100g. Statisticalanalysis using LSD test of ß-carotene levels in the Capsicum annuum L. Var. abreviatumFingerhuth, Capsicum annuum L. Var. Longum sendt) and Capsicum frutescens L. weresignificantly different at P of 0.05
PENGARUH DIABETES MELLITUS TERHADAP RESISTENSI ASPIRIN PADA PASIEN STROKE ISKEMIK DI RUMAH SAKIT BETHESDA YOGYAKARTA
Get PDFThe secondary prevention of ischemic stroke can be implemented by giving aspirin.However, some cases of aspirin resistance have been found. The purpose of this study was toexamine the influence of diabetes mellitus on the risk of aspirin resistance in ischemic strokepatients at Bethesda Hospital Yogyakarta. This study was using a nested case-control studydesign. The Cases group was subjects who resistance to aspirin therapy. The control group wassubjects who response to aspirin therapy. The factors that affect the incidence of aspirinresistance were analyzed by bivariate analysis chi square test. The proportion of diabetesmellitus in resistant group was bigger than the aspirin responsive group. Its odds ratio (OR) was1.605 (95% CI, 0.641 to 4.017) (p=0.155). Conclusion: Ischemic stroke patients at BethesdaHospital Yogyakarta with diabetes mellitus were not proved to have a bigger risk of aspirinresistance than the patients without diabetes mellitus
PENGHAMBATAN AKTIVITAS XANTHINE OXIDASE OLEH EKSTRAK ETANOL SARANG SEMUT (Myrmecodia tuberosa (non Jack) Bl.) SECARA IN VITRO
Get PDFUric acid is the end product of purine metabolism that can settle in the joints and form smallcrystals, causing inflammation known as gout. Gout is a disease caused by high levels of uric acid inthe blood (hyperuricemia). One of the drugs used to treat gout was allopurinol to inhibite the activityof xanthine oxidase mechanism. Myrmecodia tuberosa (non Jack) Bl. known to contain flavonoids andempirically proven to treat rheumatic complaints and gout. Therefore, research needs to examinewhether the ethanol extract of the sarang semut to inhibite xanthine oxidase activity. Allopurinol isused as a comparison. The active substances of the Myrmecodia tuberosa (non Jack) Bl. was extractedwith ethanol using maceration method after soaked with petroleum ether. The xanthine oxidaseinhibitor activity of the Myrmecodia tuberosa (non Jack) Bl production ethanol extract wasspectrophotometrically determined by monitoring the reducing of uric acid at a wavelength(λ) 295 nm with xanthine as substrate. Rate values obtained subsequently used to calculate the valueof the activity. Then determined the concentration of the ethanol extract can inhibit the activity ofof xanthine oxidase by 50% (IC50). The results of the research showed that the ethanol extracts of sarang semut inhibited xanthine oxidase activity with IC50 112.40 µg/ml, while allopurinol was3.16 µg/ml
EKSTRAKSI ANDROGRAFOLID DARI Andrographis paniculata (Burm.f.) Nees MENGGUNAKAN EKSTRAKTOR SOXHLET
No full textChemical component extraction from plant herbal influenced by various aspect, such asextraction technique or chemical component character from the plant. Extraction method and solventpolarity exteremly influence chemical component transfer from the cell of plant to solvent solution.Soxhlet is extraction system instrument with frequently same solvent extraction based on liquid-steamcirculation process of the solvent. Solvent polarity to extract chemical component of the plant herbaldepend on chemical component character it self and ability to penetrate cell membrane.Andrographolide, an active chemical component of Andrographis paniculata has been suggested themost active constituent that responsible to activity of Andrographis paniculata in herbal medication.This chemical constituen has solubility character in solvent with middle polarity that indicates solventelection to extract it. This study shows that chemical component extraction of herbal plant influencedby solvent polarity. Thin Layer Chromatography qualitative analyses indicate that absolute polar andAndrographis paniculatanonpolar solvent could not extract andrographolide, different from middle polarity. Andrographolideextraction with similar solvent and correct method offer extract yield with 16,6% andrographolide
EVALUASI KEPUASAN KONSUMEN TERHADAP PELAYANAN KEFARMASIAN DI APOTEK KOTA YOGYAKARTA
Get PDFCustomer satisfaction with pharmaceutical care in pharmacy can be measured bycomparing the expectations of consumers on the quality of pharmacy services desired by thefact that it received. This study was aimed to identify the dimensions of the expected quality ofpharmaceutical care, is considered important, and which has a good performance with a modelof quality pharmaceutical care to costumer at pharmacy in Yogyakarta. This study wasobservational descriptive method and the results are presented with quadrant diagram. Theresults showed that the costumer at pharmacy in Yogyakarta satisfied with pharmaceutical carein Tangible and Empathy dimension. The Tangible and Empathy dimensions are in quadrant IIof the diagram. Howefer, the Assurance, Responsiveness and Reliability dimension, costumersless satisfied because the assume of patients if the pharmacy performance is still lower than theexpectations of consumers. That showed the Assurance, Responsiveness and Reliabilitydimensions are in quadrant III of the diagram
PEMURNIAN ETANOL HASIL FERMENTASI KULIT UMBI SINGKONG (Manihot Utilissima Pohl) DARI LIMBAH INDUSTRI KERUPUK SANJAI DI KOTA BUKITTINGGI BERDASARKAN SUHU DAN WAKTU DESTILASI
Get PDFBukittinggi city with approximately 132 industry crackers Sanjai spend 300-500 kg ofcassava per day for each industry. Solid waste production process results Sanjai crackers thisone is skin cassava. Cassava’s peel produces 15-20% carbohydrate content of 68-85% of theweight of the bulb, so it has great potential to be converted into bioethanol.Carbohydrates in the tuber peel can be processed into ethanol by fermentation and for separatingethanol from it’s mixture used method of distillation. Distillation temperature and time used affects the quality and quantity of bioethanol produced. This study aims to determine the besttime and temperature distillation to produce bioethanol at the highest levels. Ethanol contentanalysis was conducted using the specific gravity using line arregression equation and Tablegravity of Indonesian Pharmacopoeia. The results showed that the highest levels of ethanoldistillate obtained in the distillation temperature of 71o C for 5 hours is 16.60% using regressionmethods and 14.1% according to Table Pharmacopoeia with yield ranging between 2.30%-5.80% and the efficiency of distillation 28, 94% -57.50%. Time and temperature distillationhave a real impact on the levels of ethanol produced atthe level of 5%
EFEK FRAKSI ETIL ASETAT EKSTRAK ETANOL AKAR PASAK BUMI (Eurycoma longifolia, Jack) TERHADAP AKTIVITAS FAGOSITOSIS MAKROFAG SECARA IN VITRO
Get PDFEurycoma longifolia has been used as a remedy for detoxification, aphrodisiaca, anticancer andimmunistimulant. The quassinoids of pasak bumi root extract, have antioxidant activity andimmunomodulatory activity by increasing IL-12. This study aims to determine the effect of the ethylacetate fraction of ethanolic extract of pasak bumi root on macrophages phagocytic activity in vitro.Macrophages were isolated from peritoneal fluid of male Balb/Cmice, and thenwere cultured for 24hours in 24 well plate. The ethyl actetate fraction ethanolic extract of pasak bumi root withconcentration of 10, 50, and 100 µg/ml, lipopolysaccharides and dimethyl sulfoxide were added, andincubated for 1.5 hours. The phagocytosis tests was carried out by adding latex with density5x104/well and incubated for 1.5 hours at incubator (5% CO2,37oC). Macrophage were then stained byGiemsa. The results showed that the percentage of active phagocytic cells treated with ethyl actetatefraction of ethanolic extract of pasak bumi root of 10, 50 and 100 µg/ml, lipopolysaccharides, anddimethyl sulfoxide were 95.4%, 90%, 85.4%, 83.4%, and 79% respectively. Phagocytic capacity attreatment levels of 10, 50, and 100 µg/ml, lipopolysaccharides,and dimethyl sulfoxide were 469; 439.8; 360.8; 204.6; and 147.6 respectively. The result showed thatreatment of ethyl acetate fractionof ethanolic extract of pasak bumi root can increase the phagocytic activity of macrophages in vitro