Biology, Medicine, & Natural Product Chemistry
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    345 research outputs found

    A Stability Mathematical Model of Nasopharyngeal Carcinoma on Cellular Level

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    This paper discussed the stability of “Tumorigenesis Models†to link between EBV and carcinoma of the nasopharyngeal from normal cell to invasive carcinoma. The review on this case accomplished the previous theorem of equilibrium point on “Tumorigenesis Modelsâ€

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    Effect of Addition of Soursop Leaf Extract to Ganyong (Canna edulis Ker.) Starch Edible Film and its application in Red Grape Storage Time

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    This study aimed to determine the effect of addition of Soursop leaf extract to  edible film and its effect on the storage time of red grapes. This research had three main steps, soursop leaf extraction, edible film making, and application on red grapes storage time. Soursop leaves extract variation used in this research are 0.5; 1; and 1.5% (w/w total) and the best result was used to coat the red grapes. The results showed that the optimum composition was obtained on the edible film with the addition of 0.5% (w/w total) soursop leaf extract. The composition increased film thickness from 0.03 to 0.08 mm, decreased film’s tensile strength from 11.89 to 8.42 MPa, decreased elongation from 12.71 to 11.03%, decreased the Young Modulus from 0.935 to 0.764 MPa, and decreased the vapor transmission rate from 7.45 to 6.55 g/m2.hour. The 50% shrinkage of weight and 50% texture damage are used as parameters to measure the Red grapes storage time. Based on weight shrinkage, red grapes storage time change from 24 days to 29 days by using an edible film coating without addition of extract, an extend to 32 days while using an edible film coating with addition of soursop leaf extract. Based on texture damage, red grapes storage time increased from 13 to 41 days if using an edible film coating without addition of extract, and increased to 40 days using an edible film coating with the addition of soursop leaf extract

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    New Record Marsdenia tenacissima (Asclepiadoideae, Apocynaceae) In Gunung Ijo Baturagung Yogyakarta

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    Marsdenia tenacissima population were found among wild bushes at S 07 o 47’ 03.4â€; E 110o 30’ 48.0†about 415 meter above sea level in Gunung Ijo Baturagung Yogyakarta. Identification was based on literature and herbarium specimen. The research was conduct using exploration methods, morphoanatomical observation, and specimen collection. Marsdenia tenacissima in Jawa was not reported in Flora of Java. Marsdenia tenacissima habitus was liana. The specific character for its identification was pollinia’s structure. This paper presented other important character namely leaf, stem, flower, pollinia, and fruit of Marsdenia tenacissima in Gunung Ijo Baturagung Yogyakarta. Accurate description and examination of any plant species were needed for its conservation and awareness of public to local biodiversity

    Histological Study of Common House Gecko (Hemidactylus frenatus) Regenerated Tail

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    Common house gecko (Hemidactylus frenatus) belongs to suborder Lacertilia that has capacity to shed its tail (autotomy) as a self-defense mechanism. After autotomy, tail regeneration occurs. Axiale skeleton of an original tail is composed of bony vertebrae, whereas the the regenerate one is comprised of cartilaginous tube. The purpose of this study was to determine the histological difference between axial skeleton of the original tail and the regenerate one of the common house gecko. Twenty four individuals consist of twelve common house gecko with original tail and twelve with regenerate tail were used. Microanatomical observations were carried on histological slide of original and regenerated tail stained with Hematoxylin-Eosin and Mallory Acid Fuchsin. The results showed that the original tail comprised of bony vertebrae whereas regenerated tail supported by cartilaginous tube

    Determination of Leisure Levels of Village Patronage UIN Sunan Kalijaga Yogyakarta: Improving Governance Patronage towards Rural Green Village and Environmentally Friendly

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    This study took place in the village of Patronage UIN Sunan Kalidjaga Yogyakarta that consist of 13 hamlets (Klidon, Banjarsari, Wonosalam, Dongkelsari, Puntuk, Tanjung Sari, Karang Lo, Purworejo, Tanjung, Banturejo, Nglengkong and Surirejo), Sukoharjo Village, District Ngaglik, DIY Sleman regency. Data are collect and analysed in order to obtain results in a level of comfort. The analysis was performed by using a formula based on the comfort level Temperature Humidity Index (THI). The results showed that Hamlet Klidon, Banjarsari, Wonosalam, and Dongkelsari shows Not Comfortable, whereas Hamlet Puntuk, Tanjung Sari, Karang Lo, Purworejo, Tanjung, Banturejo, Nglengkong, Surirejo and Mujen show Strongly Comfortable mainly on the clock 10:00 to 15:00

    The Phytoestrogenic Potential of Yam Bean (Pachyrhizus erosus) on Ovarian and Uterine Tissue Structure of Premenopausal Mice

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    The use of estrogen hormone by public has significantly been improved either as prevention or treatment of disease. Menopausal issues in women are often treated using hormone replacement therapy. In regard to this, yam bean is found to contain genistein and daidzein compounds with a chemical structure that resembles estrogen hormone, therefore yam bean is categorized in the phytoestrogen group. The purpose of this study was to identify the potential of yam bean on ovarian and uterine histology of mice. This research employed a Completely Randomized Design of experimental research approach of one factor namely yam bean in three different dosage treatment: 0.3 g/kg, 0.6 g/kg, and 0.9 g/kg of yam bean for 24 days. The surgery and organ harvesting of ovary and uterus were conducted on Day 25 along with the making of histological preparat using paraffin method and Hematoxylin-eosin (HE) staining. The data was then analyzed descriptively. This research found that there were both secondary and tertiary follicle proliferation as the antrum contains some estrogen level. Meanwhile, the endometrial tissue of the uterus experienced uterine glandular proliferation. To conclude, yam bean was found to be a natural estrogen source

    Substitution and Haplotype Diversity Analysis on The Partial Sequence of The Mitochondrial DNA Cyt b of Indonesian Swamp Buffalo (Bubalus bubalis)

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    This research aims to investigate the substitution pattern of nucleotide base and haplotype diversity of Indonesian swamp buffalo (Bubalus bubalis) based on the mitochondrial DNA cyt b partial gene sequence. 17 samples were chosen from 7 different regions with each uniquely represents Indonesian biogeography which comprise Aceh, Riau, Madiun, Blitar, Lombok, South Borneo and Tana Toraja. The result of cyt b gene sequence alignment showed the presence of transition and transversion substitutions and the absence of insertion and deletion. The amount of transitions was found to be higher than that of transversions and the amount of substitution in pyrimidine was also higher than that in purine. The highest amount of transitions happened in base TàC which is a silent substitution. The result of median joining network analysis showed that Indonesian haplotype Bubalus bubalis could be classified into 16 haplotypes which form different haplogroups unique to their geographical region. The result of median joining network analysis also indicated that the genetic relationships of swamp buffaloes (Bubalus bubalis) in Indonesia are highly influenced by their geographical locations

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