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Pharmacist Professional Work Practice In The Pharmaceutical Industry at PT. Daewoong Biologics Indonesia
No full textBackground: The pharmaceutical industry is a licensed business entity engaged in
the manufacturing of drugs and/or drug substances in accordance with existing
regulations. All manufacturing activities must comply with Good Manufacturing
Practices (GMP). Pharmacists play a key role as responsible personnel in
production, quality assurance, and quality control to ensure the safety, efficacy, and
quality of pharmaceutical products. The Professional Pharmacist Work Practice in
the pharmaceutical industry is essential to provide pharmacy students with
knowledge, skills, and practical experience in the application of GMP principles.
Objective: This Professional Pharmacist Work Practice aims to enhance the
understanding of pharmacy students regarding the roles, functions, and
responsibilities of pharmacists in the pharmaceutical industry, as well as to gain
practical experience in implementing GMP, particularly at PT Daewoong Biologics
Indonesia.
Summary: The Professional Pharmacist Work Practice was conducted at PT
Daewoong Biologics Indonesia, Jababeka, from March 3 to April 30, 2025. The
activities included placement in the Quality Control department (physical-chemical
and microbiology sections) and training in other departments. Pharmacists play a
vital role in ensuring the quality and efficacy of pharmaceutical products from raw
materials to finished products. PT Daewoong Biologics Indonesia has consistently
implemented GMP in all aspects, including quality management systems,
personnel, facilities, equipment, sanitation and hygiene, production, quality control,
self-inspection, quality audit, documentation, outsourcing activities, validation, and
qualification.
Conclusion: The Professional Pharmacist Work Practice at PT Daewoong
Biologics Indonesia provided comprehensive insights into the application of GMP
in the pharmaceutical industry, particularly in the processing of cell-based products.
Pharmacists have proven to be key personnel responsible for ensuring the safety,
quality, and efficacy of drugs. Through this program, pharmacy students gained
valuable knowledge and practical experience that support their professionalism in
the pharmaceutical industry.107 PagesKarya Tulis Profes
The Dual Role of Partonun Women of the Toba Batak Ethnic Group in Pansurnapitu Simarlalai Village, Siatas Barita District, North Tapanuli Regency
No full textThis study discusses the phenomenon of dual roles experienced by female weavers
of the Batak Toba ethnic group in Pansurnapitu Simarlailai Village. Women in this
community are not only responsible for domestic work such as taking care of the
household and children, but also play an active role in economic activities by
weaving ulos cloth as an effort to support family needs. In the Batak Toba
community which still adheres to a patrilineal kinship system, women often face
social pressure and gender inequality, which burdens their dual roles. This study
uses a descriptive qualitative approach with observation, interview, and
documentation methods for informants consisting of weavers and traditional
leaders. The results of the study show that female weavers experience physical and
psychological stress due to the demands of carrying out two roles at once. However,
they continue to show resilience and adaptive strategies such as dividing their time
efficiently and building social networks. This study emphasizes the importance of
public awareness and government support in easing the burden on women through
a fairer division of roles and economic empowerment. These findings contribute to
the study of gender anthropology, especially related to the dynamics of women's
roles in traditional societies that are transforming.Skripsi Sarjan
The Procedure For Implementation Of Tax Confiscation By Baid Officers Towards Corporate Taxpayers At Low Tax Office Of Lubuk Pakam
No full textThe Directorate General of Taxes through tax bailiffs has the authority to
carry out confiscation actions as a legal effort in order to collect and enforce
payment of tax debts from non-compliant taxpayers. However, in its
implementation, tax bailiffs still experience many difficulties in carrying out their
duties because taxpayers always avoid being confiscated due to a lack of
understanding of the confiscation procedures carried out by bailiffs.
This study aims to determine how the procedures for implementing
confiscation by tax bailiffs are against corporate taxpayers and to assess the
suitability of the procedures that have been implemented at Low Tax Office of
Lubuk Pakam dan to identify the terms and conditions that must be met by the
Directorate General of Taxes before carrying out confiscation actions and to
explain the legal efforts that can be taken by corporate taxpayers if they do not
agree with the confiscation actions taken.
This study was conducted using a qualitative descriptive research method. The
location of the study was at Low Tax Office of Lubuk Pakam, which is located at
the State Finance Building, Floors 2 and 4, Jl. Pangeran Diponegoro No.30A,
Madras Hulu, Medan Polonia District, Medan City, North Sumatra Province. The
study was conducted in April 2025 to May 2025.
The results of this study indicate that the confiscation procedure by tax bailiffs
begins with the issuance of a writ of execution, then a confiscation order, followed
by the implementation of the confiscation and the issuance of a report. The study
also shows that the confiscation actions carried out by the bailiffs at Low Tax
Office of Lubuk Pakam are in accordance with applicable laws. The terms and
conditions that must be prepared by the Directorate General of Taxes before
carrying out a confiscation are that the taxpayer's debt is due, issuing a writ of
execution, and the confiscation must be carried out by an authorized bailiff. The
results of this study indicate legal remedies that can be taken by corporate
taxpayers if they do not agree with the confiscation actions taken, filing a lawsuit
with the tax court, and being able to submit a judicial review to the Supreme Court.78 PagesKertas Karya Diplom
The Effect of Individual Characteristics and Personal Hygiene on Skin Disorders in Scavenger in Final Waste Disposal Site in Terjun Village Medan Marelan
No full textSkin disorders are among the most common health problems worldwide, affecting nearly 900 million people. Occupational skin diseases are particularly prevalent, with waste pickers being among the most vulnerable groups due to their high-risk working environments. Factors contributing to skin disorders among waste pickers include biological exposures in the workplace-such as fungi, viruses, and bacteria found in waste-as well as behavioral factors such as the use of personal protective equipment (PPE) and personal hygiene practies. This study aimed to analyze the influence of individual characteristics and personal hygiene on skin disorders among waste pickers at the Terjun Landfill in Medan Marelan. This research employed a cross-sectional design with a total sample of 82 waste pickers. Bivariate analysis was conducted using the chi-square test, while multivariate analysis was performed using logistic regression. The results showed that 71 respondents (86.6%) experienced skin disorders. There were significant associations between skin disorders and work duration (p = 0.005), medical history (p = 0.001), PPE use (p = 0.003), skin hygiene (p = 0.007), and hand, foot, and nail hygiene (p = 0.001). Further analysis revealed that medical history (p = 0.041), skin hygiene (p = 0.007), and hand, foot, and nail hygiene (p = 0.001) significantly influenced the occurrence of skin disorders among waste pickers. The most dominant factor was skin hygiene, with an Exp.B value of 39.603. It is recommended that waste pickers at the Terjun Landfill, Medan Marelan consistently use complete PPE while working and maintain good personal hygiene practices such as cleaning their entire body after work, changing work clothes daily, and washing them thoroughly.
Keywords: Skin disorders, personal hygiene, landfill191 PagesTesis Magiste
Strategies for Strengthening Employment Social Security for Informal Workers in Increasing Participation in the BPJS Ketenagakerjaan Lhokseumawe
No full textImplementation of BPJS Ketenagakerjaan is to realize the fulfillment of essential protection and a decent life for every worker and his family through a social security system, which is implemented based on Undang-Undang Number 24 of 2011 concerning the Social Security Organizing Agency. Informal sector workers have little formal education, no special skills, and lower incomes than formal workers. Informal workers can enroll in a minimum of 2 programs, including the Work Accident and Death Insurance Program, and They can choose an additional Old Age Security program for their old age savings. The number of workers not registered in the BPJS Ketenagakerjaan program is an obstacle for the BPJS Ketenagakerjaan Lhokseumawe in expanding BPJS Ketenagakerjaan membership coverage. This research was made to formulate strategies and policies to increase the participation of informal workers in the BPJS Ketenagakerjaan Lhokseumawe and analyze the inhibiting and influencing factors in increasing BPJS Ketenagakerjaan membership in informal workers in Lhokseumawe City. The type of research used is qualitative research combining two analysis techniques, SWOT analysis and Systematic Literature Review (SLR). Data collection is in the form of observation, interviews and documentation. Survey conducted among informal workers. Data analysis was applied through SWOT Space Matrix and QSPM analysis. The selection of strategies that are in accordance with the analysis is that BPJS Ketenagakerjaan can take advantage of the MLT program for scholarships for workers children to register the increasing number of informal numbers in increasing the membership of the informal program.105 PagesTesis Magiste
Analysis of Financial Statements to Measure Financial Performance Based on Profitability Ratios at PT. Bank Mandiri Tbk in 2022-2024
No full textThis study aims to analyze the financial performance of PT Bank Mandiri Tbk during the 2022–2024 period using profitability ratios, including Net Profit Margin (NPM), Return on Assets (ROA), and Return on Equity (ROE). The analysis was conducted to determine how efficiently the company generates profits through its management of revenue, assets, and equity. The method used is descriptive quantitative, utilizing secondary data obtained from the company’s annual financial statements published on the official website and the Indonesia Stock Exchange. Profitability ratios were calculated for each year to assess the financial performance trend over three consecutive years. The results show that the NPM and ROA ratios are categorized as excellent based on industry standards, with average values of 40.7% and 2.52%, respectively. This reflects strong operational efficiency and effective asset management. However, ROE remains in the poor category with an average of 19%, despite a temporary increase in 2023. Overall, PT Bank Mandiri Tbk demonstrates positive financial performance, particularly in operational efficiency and asset utilization. Nevertheless, improvements are still needed in the effective use of equity to optimize returns for shareholders.51 PagesKertas Karya Diplom
Manufacture of Semi-Mechanical Palm Processing Tools to Become CPO (Crude Palm Oil)
No full textAt the moment, the demand for fried oil in the global market is very high, as
is Indonesia, where the demand is growing every day and the fried petroleum
market in Indonesia is dominated by palm coconut oil. The plantations that this
individual owns usually produce only the raw fruit of the palm tree without any
processing. Therefore, the purpose of this research is to make a semi-mechanical
palm processing device into a crude palm oil (CPO) where this tool functions to
crushed the palm with a knife inside it that is driven by a propulsion motor which
will produce CPO. The results indicate that the effective capacity of the palm oil
processing equipment is 127.40 kg/hour. The average yield obtained when using
this equipment is 16.22%. Fuel consumption is 2.56 l/hour. For the economic
analysis, the Break-Even Point (BEP) value obtained 11,964.71 kg/year. The NPV
at an interest rate of 6% is 15,411,655.45 IDR/ year, and at an interest rate of 20%,
the NPV is -646,364.07IDR. The IRR obtained is 19.44%, This tool is very helpful
for palm oil farmers in producing crude oil, as it has a higher economic yield
compared to just selling fresh fruit bunches or raw palm fruit.114 PagesSkripsi Sarjan
Bio-Oil Characteristics of Three Types of Mangrove Branches
No full textMangrove wood is known to have a high calorific value; therefore, it has
traditionally been used as a source of firewood by our ancestors. Continuous
exploitation has caused mangrove forests to degrade and their ecological functions
to diminish. For this reason, this study utilizes only the branch parts of mangrove
wood to ensure that mangrove forests remain preserved and sustainable.
Furthermore, this research focuses on diversifying energy sources. Previous studies
have produced briquettes, pellets, charcoal, and charcoal briquettes from
mangrove wood branches. A byproduct of charcoal conversion is bio-oil, which can
also be used as an energy source. In this study, three types of mangroves, namely
black mangrove (Rhizophora mucronata), tancang (Bruguiera gymnorrhiza), and
mata buaya (Bruguiera sexangula), were pyrolyzed to produce charcoal and bio
oil. The bio-oil was characterized to evaluate its contents and subsequently
recommend potential uses. Characterization results included yield, viscosity, pH,
and chemical properties using GC-MS analysis. The results showed that R.
mucronata had the highest viscosity of 1.9 and contained the most variations of
compounds, with 12 chemical components. B. gymnorrhiza had the highest pH of
3.94 and contained 8 chemical components. B. sexangula had a viscosity of 1.9 but
only contained 2 compound components. Further research should be conducted for
the feasibility as energy source.44 PagesSkripsi Sarjan
Analysis of Freshwater Biota Growth in an Aquaponic Ecosystem
No full textThis study examines the impact of ammonia levels on the development of freshwater biota, with a special focus on snakehead fish (Channa striata) and spinach (Amaranthus sp.) in an aquaponic ecosystem. The experiment was conducted using a closed circulation aquarium, where several environmental parameters, namely pH, water temperature, air temperature, air humidity, dissolved oxygen (DO), electrical conductivity (EC), and total dissolved solids (TDS) were monitored using a sensor fusion system. The values of these parameters were then correlated with the concentration of ammonia in the aquarium. Ammonia in the aquarium comes mainly from fish metabolic waste, such as feces and urine, as well as rotting food waste and other organic materials. Ammonia is useful as a nutrient for plants in the form of nitrate (NO₃⁻), but interferes with development and is harmful to fish in the form of nitrite (NO2⁻). Fish were fed twice a day, in the form of pellets in the morning and maggots in the afternoon. Growth responses were measured based on the length and weight of the fish, as well as the height and number of leaves of the plants. Using Pearson Correlation Coefficient, the correlation values between ammonia concentration and pH, DO, EC, TDS, air humidity, air temperature, and water temperature were sequentially 0.50, 0.09, 0.14, -0.07, -0.01, -0.20, and -0.22. Meanwhile, the K-means algorithm was used to detect data anomalies. The results showed that snakehead fish (Channa striata) and spinach (Amaranthus sp.) can thrive in an environment with an ammonia concentration of 1 mg/L or below.83 PagesTesis Magiste
Association Between Neutrophil-Lymphocyte Ratio in Coronary Artery Bypass Grafting and Acute Kidney Injury at H. Adam Malik General Hospital Medan
No full textBackground: Acute Kidney Injury (AKI) is a notable postoperative complication in patients undergoing Coronary Artery Bypass Grafting (CABG). The Neutrophil-Lymphocyte Ratio (NLR) is an inflammatory marker that may be associated with postoperative AKI. This study aimed to evaluate the relationship between NLR and AKI in CABG patients at H. Adam Malik General Hospital Medan.
Methods: This retrospective cohort study included 60 patients who underwent on-pump or off-pump CABG. Preoperative NLR and postoperative AKI were obtained from medical records, and AKI was assessed using AKIN criteria. Statistical analysis was performed to evaluate the association between NLR and AKI, with a significance level of p<0.05.
Results: Most patients had normal NLR values (83.3%), and AKI occurred in 15% of cases. The mean NLR was 2.36 in the on-pump group and 2.47 in the off-pump group. There was no significant association between NLR and AKI (p=0.417). There was also no significant association between surgical technique and AKI (p=0.723).
Conclusion: There was no significant relationship between NLR and AKI in CABG patients, and the type of surgical technique did not influence AKI incidence.64 PagesTesis Magiste