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Evaluation of in vitro and in vivo activities of flavophospholipol against conjugative transfer of antimicrobial resistance genes
酪農学園大学獣医学Thesisdoctoral thesi
書籍紹介 : 『SDGsな野生動物のマネジメント狩猟と鳥獣法の大転換』羽澄俊裕著 : 2022年2月 地人書館発行 237頁 定価 3,520円(本体3,200円+税)
Articlejournal articl
北海道岩見沢市において発生したアカエリヒレアシシギの集団死
Article2010年9月,北海道岩見沢市にて,アカエリヒレアシシギ Phalaropus lobatus が集団で死亡しているのが見つけられた.栄養状態は良好で,剖検所見から何らかの衝突事故であることが示唆された.A mass mortality event involving 13 Red-necked Phalarope Phalaropus lobatus occurred in a suburb of Iwamizawa, Hokkaido, northern Japan, in September, 2010. Gross postmorterm examinations revealed that they were in good condition with healthy levels of subcutaneous fat, but they had sustained injuries suggesting that they died from a fatal collision.journal articl
Relationship between Escherichia coli virulence factors, notably kpsMTII, and symptoms of clinical metritis and endometritis in dairy cows
journal articleAlthough Escherichia coli is a commensal bacterium of the bovine vaginal microbiota, it is an important pathogenic bacterium that causes diseases of the reproductive tract and sub-fertility. Recent studies have focused on virulence factors (VFs) of intrauterine E. coli; however, actual endometrial VFs have not been clearly identified. The purpose of this study was to identify the VFs of E. coli associated with clinical metritis and endometritis. Thirty-two strains of E. coli and four mixed Trueperella pyogenes (TP) strains were detected in the uterus of 19 Holstein dairy cows with obvious clinical signs (between 8 and 66 days postpartum). The presence of six E. coli VFs (fimH, fyuA, kpsMTII, hra1, csgA, and astA) was examined by PCR, and clinical signs and reproductive performance (mixed TP, the percentage of polymorphonuclear neutrophils [PMN%], days to uterine involution, etc.) were evaluated. Four VFs (fimH, hra1, csgA, and astA) were detected in all E. coli strains, whereas fyuA and kpsMTII were detected in 94% and 50% of strains, respectively. Cows with E. coli strains harboring kpsMTII exhibited significantly severe clinical scores (vaginal discharge score, PMN%, uterine involution), suggesting that kpsMTII is a key VF for progression of clinical metritis and endometritis. In the present study, we clearly identified six VFs associated with clinical metritis and endometritis. In addition, E. coli strains with kpsMTII probably play a crucial role in the progression of clinical metritis and endometritis.journal articl