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Effect of nutritional management on immune status, gastrointestinal parasite infection and productivity in sheep
Get PDF酪農学園大学修士（酪農学）Thesismaster thesi
The Transition from the Human and Farmland Plan to Regional Plan and the Development of New Entrants
Get PDFBulletin本論文の目的は，農業政策である人・農地プランが地域計画に移行するなかで，新規参入者の受け入れおよび育成方針を考察することである。人・農地プランと地域計画の相違は農地の受け手の明確化である。地域計画においてはいつ現れるとも分からない新規参入者を農地の受け手として位置付けることが困難になる可能性がある。しかし，事例分析では第三者継承の活用や新技術の導入によって新規参入者を位置付けることが可能となっていた。そうした状況を実現するには地域での徹底した話し合いが必要であると考えられる。This study aims to examine the policy of accepting and nurturing new entrants as an agricultural policy, the Human and Farmland Plan, and transitions to the Regional Plan. The key difference between the Human and Farmland Plan and Regional Plan is the clarity about who will take over the farmland. In the Regional Plan, positioning new entrants as recipients of farmland can be challenging since it is uncertain when they will appear. However, case studies have shown that new entrants can be positioned by employing third-party succession and introducing new technologies. To achieve this, a thorough discussion within the community is necessary.departmental bulletin pape
Mary Magdalene, First Witness of Jesus' Resurrection : Tradition and Redaction in John 20 : 11-18
Get PDFBulletindepartmental bulletin pape
Is motilin a physiological regulator of rabbit gastrointestinal motility?
Get PDFBulletinIt has been 50 years since motilin was discovered from porcine duodenal mucosa. To understand functional roles of motilin, many physiological/pharmacological studies have been done using synthetized motilins. In addition, distribution of motilin in tissues and change in plasma motilin level were investigated using specific motilin antibodies. Furthermore, analysis of motilin precursor gene was conducted using a molecular biological approach, and it has been reported that motilin is present in many vertebrates including mammals. However, mice, rats, and guinea pigs, commonly used in physiological/pharmacological studies, do not express the motilin/motilin receptor genes and do not respond to motilin. This is one of the reasons for delay of motilin research. Since motilin is a gastrointestinal (GI) motility stimulating hormone, the physiological roles of motilin for regulation of GI motility have been examined mainly in mammals. The responses of motilin varied markedly depending on the experimental conditions (in vivo, in vitro), animal species and GI regions, but it has been found that motilin is an endogenous mediator of the phase 3 of migrating motor complexes (MMCs) originating from stomach during the fasting period at least in humans, dogs, suncus, monkeys, and opossums. MMCs transport a hunger signal from stomach to the brain and sweep up the GI lumen as a housekeeper. Rabbits have been used for in vitro studies and contributed to a field of motilin research such as the discovery of receptors, agonists and antagonists, and the establish of structure-activity relationship. Although rabbits GI tracts reveal the intestinal MMCs, they eat small amounts of food frequently (different feeding pattern from humans and dogs) and there are no clear fasting periods. Therefore, the characteristics of MMCs are different from those of humans and dogs. Involvement of motilin in the regulation of MMCs in rabbit upper GI tracts are not cleared at present. On the other hand, the concentration of motilin receptor in the colon is the highest among the GI tract and it is possible that motilin regulates the colonic motility, such as giant migrating contractions in rabbits. However, the answer has not been obtained yet. Further functional studies and simultaneous measurement of plasma motilin level are required to understand physiological role of motilin in rabbits. Motilin is an interesting peptide but there are still unknown functions in some species. We are looking forward to performing further extension of motilin research in next 50 years.departmental bulletin pape
