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Efficient terahertz spin-to-charge current conversion in IrAl compounds
No full textThe interconversion between spin and charge currents is vital for developing spintronics technologies, which require materials with high
spin-to-charge-current conversion efficiency (SCC). The alloy IrAl was shown to exhibit a large spin Hall angle at gigahertz frequencies.
Here, we use spintronic terahertz emission spectroscopy to investigate terahertz SCC in IrxAl1 xjFM heterostructures with a ferromagnetic
layer FM of CoFeB and Ni as a function of the composition ratio x. We observe a strongly x-dependent terahertz-signal amplitude, whereas
no change in the dynamics of the ultrafast in-plane charge current is seen. For x ¼ 0:48, we find that the SCC efficiency in IrxAl1 x reaches
up to 65% of that of Pt. Signals from IrxAl1 xjNi suggest that orbital contributions to the signal are minor. This study highlights the potential
of IrAl alloys for SCC in ultrafast spintronic applications
MLUH-E-168_1, Accipiter gentilis gentilis (Linnaeus, 1758), eggshell
No full textInventory No.: MLUH-E-168_1, Object: eggshell, Species: Accipiter gentilis gentilis (Linnaeus, 1758), Preservation: good preservation, Locality_loc.: Cean bei Straelen/ Kreis Geldern, Locality today: Kleve, Country: GermanyCollector_leg.: L. Geyr von Schweppenburg, Date: 29/04/1925, Collection_coll.: M. Schönwetter, published in Handbuch der Oologie, Schönwetter, Max: Vol. I, p. 157, Identification by: M. Schönwetter, Aquisition: 1941, Aquired from: L. Geyr von Schweppenburg, ex Collection: ex.Coll. L. Geyr von Schweppenburg, Additional Information: extra letter says aquired from Dr. v. Jordan
Short-course radiotherapy versus long-course chemoradiotherapy in total neoadjuvant therapy of rectal cancer : a multicenter analysis of early outcomes and toxicity
No full textBackground and Purpose
Total neoadjuvant therapy (TNT) improves local control and complete response (CR) rates in locally advanced rectal cancer (LARC). CR is associated with favorable local tumor control, allowing non-operative management (NOM). However, it remains unclear whether short-course radiotherapy (SCRT) or long-course chemoradiotherapy (LCRT) is preferable within TNT.
Methods
LARC patients undergoing TNT between 2015 and 2024 were included in this retrospective multicenter analysis (DRKS00033000). The primary endpoint was CR. Secondary endpoints comprised NOM rates, toxicity, and tumor control. Multivariable logistic regression modelling was used to assess the influence of LCRT.
Results
Of 295 included patients with a median age at diagnosis of 62 (Q1-Q3: 54–68) years and 210 (71.2 %) men, 172 (58.3 %) underwent LCRT. CR was achieved in 46 (37.4 %) SCRT and 96 (55.8 %) LCRT patients. Acute toxicity grade ≥ 3 occurred in 24 (20.5 %) of 117 SCRT and in 62 (36.3 %) of 171 LCRT patients. Within a median follow-up of 19.4 months (SCRT) and 19.6 months (LCRT), 23 (19.8 %) of 116 and 30 (19.4 %) of 155 patients experienced recurrence, respectively. Regression modelling revealed an increased likelihood for CR (adjusted odds ratio: 3.11; 95 % confidence interval: 1.37–7.07) and NOM (4.40; 1.46–13.21) with LCRT, whereas no significant associations of LCRT with acute toxicity (0.90; 0.40–2.02), chronic toxicity (1.16; 0.48–2.78), postoperative complications (0.89; 0.62–1.28) or recurrence (0.81; 0.31–2.16) were observed.
Conclusion
LCRT was associated with higher CR and NOM rates. Whether it might be preferred over SCRT for intended NOM remains a relevant question to be answered by ongoing randomized trials
MLUH-E-262_1, Buteo japonicus Temminck and Schlegel 1845, eggshell
No full textInventory No.: MLUH-E-262_1, Object: eggshell, Species: Buteo japonicus Temminck and Schlegel 1845, Preservation: slight damage, Locality_loc.: Oka Kiusshiu Japan, Locality today: [Kyūshū] Japan, Country: JapanCollector_leg.: [Dr. Komar], Date: 23/05/1902, Collection_coll.: M. Schönwetter, published in Handbuch der Oologie, Schönwetter, Max: Vol. I, p. 167, Identification by: M. Schönwetter, Aquisition: 1904, Aquired from: O. Bamberg, ex Collection: ex. Coll. O. Bamberg; ex. Coll. Dr. Komar, Additional Information: Dr. Komars collections dates are to close to each other to be feasabl
MLUH-E-25_1, Falco chicquera chicquera Daudin, 1800, eggshell
No full textInventory No.: MLUH-E-25_1, Object: eggshell, Species: Falco chicquera chicquera Daudin, 1800, Preservation: complete preservation, Locality_loc.: Umbala, Ostindien, Locality today: India, Country: IndiaDate: ?, Collection_coll.: M. Schönwetter, published in Handbuch der Oologie, Schönwetter, Max: Vol. I, p. 192, Identification by: M. Schönwetter, Aquisition: 1910, Aquired from: Dr. Rey, ex Collection: ex. Coll. Dr. Rey, Additional Information: Dr. Rey 1
Behavioral climate change : does thinking about future consequences of climate change affect risk preferences and cooperation?
No full textHuman-made climate change is one of the most pressing challenges of the 21st century. This paper examines how thinking about future consequences of climate change influences decision-making. Using priming experiments, we address ambiguity preferences, risk preferences, and willingness to cooperate among farmers, students, and representatives of the general population of Germany. The results show that farmers (who were asked specifically about the consequences for their profession) – but not students or representatives of the general population – increase their investments in uncertain assets. There are also common patterns across the subject pools, most notably willingness to cooperate remains largely unchanged
Bleomycin electrosclerotherapy (BEST) of slow-flow vascular malformations (SFVMs) in children
No full textRationale and objectives
Bleomycin electrosclerotherapy (BEST) is a promising treatment for slow-flow vascular malformations (SFVMs). Due to limited paediatric data, this study aimed to assess the safety, effectiveness, and patient-reported outcomes of BEST in children with SFVMs.
Material and methods
This monocenter cohort study included patients <18 years with symptomatic SFVMs treated by BEST. Patient records were analysed for procedural details and complications. Symptom severity was objectively classified before and after BEST. A treatment-specific, patient-reported questionnaire assessed mobility, aesthetic concerns, swelling, social participation, pain using a visual analogue scale (VAS), and post-procedural skin discoloration. Outcomes were compared between simple and infiltrative lesions.
Results
Overall, 68 BEST sessions were performed in 45 children. Total complication rate was 10/68 (14.7 %), most commonly pes equinus deformities (5/68, 7.4 %) after treating SFVMs in calf muscles. Physician-rated overall symptom severity improved significantly (p < 0.001). Treatment-specific, patient-reported questionnaire revealed improved mobility in 14/41 (34.1 %) and symptom-free patients in 10/41 (24.4 %). Outcome in both aesthetic measure and social participation was mostly rated as improved or perfect (33/41, 80.5 %; 35/41, 85.4 %). Median VAS pain scale improved significantly (2.0 vs. 0.0, p < 0.001). Postprocedural swelling occurred in all children, in 26/41 cases (64.4 %) persisting for 2–4 weeks. Postprocedural skin discoloration (41/41, 100 %) was mostly (25/41, 61.0 %) reported to fade over time. No differences between simple and infiltrative lesions were revealed in all outcome parameters.
Conclusion
BEST is effective for paediatric SFVMs by objective and subjective measures while maintaining low complication rates. Notably, BEST achieves therapeutic success even in infiltrative SFVMs expanding the range of available treatment options
MLUH-E-250_1, Buteo hemilasius Temminck and Schlegel, 1845, eggshell
No full textInventory No.: MLUH-E-250_1, Object: eggshell, Species: Buteo hemilasius Temminck and Schlegel, 1845, Preservation: complete preservation, Locality_loc.: Amur, Locality today: Russia/China, Country: Russia/ChinaDate: ?, Collection_coll.: M. Schönwetter, published in Handbuch der Oologie, Schönwetter, Max: Vol. I, p. 164, Identification by: M. Schönwette
MLUH-E-54_1, Falco columbarius Linnaeus, 1758, eggshell
No full textInventory No.: MLUH-E-54_1, Object: eggshell, Species: Falco columbarius Linnaeus, 1758, Preservation: complete preservation, Locality_loc.: [?Lappland], Locality today: [Russia/Finland/Sweden/Norway], Country: [Russia/Finland/Sweden/Norway]Collection_coll.: M. Schönwetter, published in Handbuch der Oologie, Schönwetter, Max: Vol. I, p. 191, Identification by: M. Schönwetter, Additional Information: Marked with a 16; with a microfisure/crack; Label in box says "Lappland" for both egg
Multiparametric MRI-based biomarkers in the non-fluent and semantic variants of primary progressive aphasia
No full textBackground:
The non-fluent (nfPPA) and semantic (svPPA) variants of primary progressive aphasia exhibit distinct clinical features. We investigated whether diffusion tensor imaging (DTI) and atlas-based volumetry (ABV) could reveal divergent patterns of longitudinal changes in brain white matter microstructure and gray matter volumes.
Methods:
MRI datasets from 29 nfPPA, 27 svPPA, and 39 controls were analyzed. White matter fractional anisotropy (FA) differences were assessed using unbiased Whole Brain-based Spatial Statistics (WBSS) and Tract-Wise Fractional Anisotropy Statistics (TFAS). Gray matter volumetric differences were calculated by Atlas-Based Volumetry (ABV). A subset of 10 nfPPA and 6 svPPA patients underwent longitudinal MRI at 12 months. FA maps were correlated with disease severity (FTLD-CDR sum of boxes). A random forest classifier validated tracts of interest (TOI) and structures of interest (SOIs) selection as a proof-of-concept.
Results:
At baseline, nfPPA showed frontal, callosal, and temporal white matter degeneration, while the left inferior longitudinal fasciculus (ILF) was predominantly involved in svPPA. Longitudinally, nfPPA exhibited frontal, callosal, and posterior temporal progression, while svPPA showed localized antero-posterior ILF progression. ABV aligned with the DTI analyses, demonstrating volumetric reductions in the frontal lobe for nfPPA and in temporal lobe and subcortical limbic structures in svPPA. Sub-clusters of white matter damage progression correlated with worsening FTLD-CDR scores. Random forest analysis identified the most discriminative TOIs and SOIs.
Conclusions:
Distinct degeneration patterns emerged across nfPPA and svPPA, supporting early differential diagnosis and correlating with disease worsening. These findings support the utility of combined DTI and ABV in tracking disease progression