Mount Kenya University Institutional Repository
Not a member yet
    5772 research outputs found

    Factors Affecting Revenue Growth in County Governments; Case study of Machakos County

    No full text

    Determination of errors that compromise the quality of clinical chemistry laboratory service delivery at Kenyatta National Hospital

    No full text
    The study established the level of pre-analytical, analytical, and post analytical errors found in the analysis of Clinical Chemistry Laboratory specimen at Kenyatta National Hospital, Kenya. This study adopted a descriptive survey design as the main approach and targeted 346 sampled specimens and request forms received. All the laboratory request forms, specimens/samples and dispatch of results were scrutinized and errors documented as per the different variables in the different phases, over a period of three months in the Clinical Chemistry Laboratory. The study aimed at establishing the levels of laboratory errors in all the phases. Results of the study showed that Preanalytical errors were most common with a frequency of 148(42.8%), statistically significant (P < 0.0001),followed by analytical errors 114 (32.9%), statistically significant difference (Chi-square, 155.5; df, 1; P < 0.0001), and post analytical errors 84 (24.3%), There was a statistically significant difference (Chi-square, 198.4; df, 1; P < 0.0001) . Preanalytical errors found included request forms lacking address, tests not done in clinical chemistry laboratory, specimen drawn in wrong tube and specimen without request forms , while analytical errors found include reagent out of stock , inadequate sample during test runs , haemolyzed samples and double registration of specimen, and lastly is the post analytical errors found the following uncollected results, critical values not communicated results lost and unreviewed results. Clinical Laboratory error reduction, prevention and high quality laboratory service delivery requires team work, involving collaboration, coordination and effective communication among all health care workers. The study concludes that the development and adherence to standard operating procedures will minimize this errors, forecasting of reagents and critical results to be communicated immediately to the respective clinics or ward Team leaders for prompt action, the study also recommends that there is need for routine, schedule Clinical laboratory audits and implementation of Laboratory information system towards quality laboratory service delivery

    Immunotherapeutic treatment of HIV-1: review of safety and efficacy

    No full text
    Background: For over two decades, the treatment of HIV-1 patients has relied on antiretroviral (ART). These drugs have had a great deal of achievement in not only controlling the viral load but also partly reconstituting the immune system in HIV-1 infected persons. However, the misfortune is that ART is a lifelong treatment because it cannot achieve complete eradication of HIV-1 virus, yet with its side effects like many other drugs. Scientists have hence introduced immunotherapy in an effort toward complete eradication of HIV-1 in HIV/AIDS patients. Objective: The aim of this paper was to determine the effectiveness and safety of the various immunotherapy formats used in the treatment of HIV-1 infection. Method: We reviewed a number of peer-reviewed published articles to determine the effectiveness and safety of the different immunotherapy formats tested in randomized clinical trials and animal model experiments. Results: Majority of immunotherapy regimens used in combination with ART to treat HIV-1 positive human or animals were found to be effective in boosting the cell-mediated immune responses in HIV-1 infection but achieved insignificant results in controlling the viral load in these experiments. Most of the immunotherapy formats were also well tolerated recording minimal to no adverse effects on HIV-1 patients. Conclusion: Most immunotherapy agents are relatively effective and safe when used in combination with ART in modulating immune response to HIV-1. These immunotherapy agents do not significantly reduce the viral load and hence cannot eliminate HIV-1

    An investigation on causes of low transition of girls from primary to secondary school in Kaasala location, Ikutha sub-county

    No full text
    Studies in Kenya and elsewhere have shown that generally there is low transition rate of girls from primary to secondary schools especially in arid and semi arid areas.Kasaala location lies in the arid and semi arid class according to government geographical data available. studies have also shown that areas with few economic activities, low or no rainfall are more affected by this trend of low transition rate of girls from primary to secondary school . Most residents of Kasaala location are poor owing to lack of enough rain.Many are times when crops have failed to produce due to inadequate necessary water for growth of plants. The purpose of the study was to investigate causes of low transition rate of girls from primary to secondary school. The specific objectives of the study was to find out the role of parental attitude, parental level of education, cultural beliefs and the distance from home to the nearest school on low transition of girls from primary to secondary school. The cost of secondary education and teacher characteristics also contribute to the low transition rate of girls form primary to secondary school. The study adopted the ex post facto research design that assisted the researcher to show how the above factors explain the low transition rate of girls from primary to secondary school. The target population of this study included the standard seven and eight pupils and their head teachers, secondary school students and their principals in Kassala location. Through purposive sampling technique at least 20% of public primary and secondary schools were selected . The students and pupils for study were selected by random sampling .The head teachers and principals were purposively sampled . The main instrument of data collection was a questionnaire. Descriptive statistics such as frequency distribution , percentages, means and standard deviations was calculated and data presented in form of tables, graphs and charts. The data was analyzed using computer programming. The descriptive and inferential statistics was used to analyze the data disaggregated by gender. The data which was collected was recorded in tables. The tables contained columns for category of questions which showed the respondents answers . The tables answer entering frequency . Each of the answers was worked also showed columns for in percentages and recorded. After all the responses formed the questionnaires made comments, which was treated as analysis of information. All the information from the tables was presented in graphs and charts

    1,113

    full texts

    5,772

    metadata records
    Updated in last 30 days.
    Mount Kenya University Institutional Repository
    Access Repository Dashboard
    Do you manage Open Research Online? Become a CORE Member to access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard! 👇