Publications scientifiques de l'Université de Reims Champagne-Ardenne
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"Requalification d’une vente à prix fictif en donation déguisée" comm. sous Avis du Comité de l'abus de droit fiscal, Séance n° 3/2024
No full textInternational audienc
Bilan de la surveillance épidémiologique SAGIR sur l’espèce Busard de maillard (Circus maillardi), La Réunion, 2016-2024
No full textLe Plan national d’actions (PNA) en faveur du Busard de Maillard Circus maillardi (2022 – 2031), également appelé localement « papangue », est coordonné par la Direction de l’Environnement, de l’Aménagement et du Logement (DEAL) de La Réunion, qui en a confié l’animation à la Société d’Etudes Ornithologiques de La Réunion (SEOR). SAGIR, le réseau de surveillance de la santé de la faune sauvage terrestre vertébrée coordonné par l'OFB, s’appuie sur un réseau d’observateurs (SEOR, Parc national de La Réunion...), sur le Laboratoire Départemental d’Analyses (LDA, Département Réunion) et sur des laboratoires spécialisés si besoin. Ce réseau participe à l’action 2.5 du PNA : Assurer une épidémiosurveillance sanitaire. L’objectif de cette action est d’assurer une veille sur les mortalités de busards endémiques et d’identifier, par une approche diagnostique, la ou les causes de la mort (effet morbide et co-morbidité). Le présent rapport dresse le bilan de la surveillance menée sur cette espèce
Improved Full Control of Variable-Pitch Wind System Based on the DFIG using Third Order Sliding Mode Control in All Operating Zones
No full textInternational audienceThis paper suggests full control of a variable-pitch wind system (VPWS) based on a doubly fed induction generator (DFIG); by using the maximum power point tracking (MPPT) and pitch angle control strategies by employing a third order sliding mode controller (TOSMC) to ensure a better performance against stochastic wind variations. Knowing that the TOSMC constitutes an effective and promising solution regarding the minimization of the chattering caused by the first and second order sliding mode controllers on the one hand and on the other to ensure fast and good tracking. In this context, the MPPT strategy has been designed with the TOSMC to ensure maximum exploitation from the VPWS on the one hand, on the other hand, the pitch angle control strategy has been designed to limit the power extracted to its maximum value as well as to ensure the stability of the VPWS against high wind speeds. To test the robustness of the proposed controller, a comparative study between the other controllers was performed. Simulation results are validated using two different wind speed profiles (step and random change of wind speed) under Matlab/Simulink environment. The results obtained demonstrated the robustness of the proposed controller compared to other conventional controllers
Le verre de l'amitié: Alcool et droit dans la série Amicalement vôtre
No full textInternational audience« Une gorgée de rhum blanc, ajoutez un peu de citron, du vermouth frais non glacé et une petite dose de grenadine. Agitez longuement. Ajoutez la glace pilée. J’insiste. Agitez et servez dans une coupe. Et mettez une olive ».Cette recette de cocktail, le créole crème, est donnée par Lord Brett Sinclair dans le premier épisode d’Amicalement vôtre. Dans cette série, Roger Moore incarne un aristocrate britannique et Tony Curtis joue le rôle d’un homme d’affaires américain, Danny Wilde.À côté d’une dimension juridique, les intrigues sont l’occasion de revenir sur la place de l’alcool dans une société donnée, à un moment de son histoire. La mise en images du droit de l’alcool invite le spectateur à étudier les réglementations en la matière, la marque ou l’appellation. La richesse des scénarios apparaît aussi dans leur arrière-plan symbolique, l’alcool constituant un prisme inattendu pour analyser l’identité et les relations contractuelles
Milton in Veneto. The Circulation of the First Illustrated Italian Translation of 'Paradise Lost'
No full textInternational audience'Paradise Lost' is a good example of the circulation of texts and books in 18th century Europe, as the work progressively became a majorreference in the epic tradition. The paper focuses on the first illustrated Italian edition of the text, as part of a wider project on Milton on the continent. In the history of this translation, cultural intermediaries, such as Paolo Rolli, the translator, but also a variety of actors (English travellers, Italian dilettanti, the Veronese publisher) play a major part as well as the will to establish Milton as a literary masterpiece. The form of the book, an in-12o and a folio edition, conceived together and illustrated (which is unusual for a first launch) is as significant as the critical paratext included in the volume. They both advocate for the literary status of Paradise Lost. Although banned by the Vatican, the folio edition was present in most convent libraries in Veneto. In some of these copies traces of reading or interventions on the images give a concrete testimony of appropriation practices
La barbe du sapeur n'est pas celle du pompier ?
No full textInternational audienceNote sous CE, ord., 18 octobre 2024, no 492819 (inédit au Lebon
A summer in the greater Paris: trophic status of peri-urban lakes shapes prokaryotic community structure and functional potential
No full textInternational audienceWith more than 12 million inhabitants, the Greater Paris offers a "natural laboratory" to explore the effects of eutrophication on freshwater lake's microbiomes within a relative restricted area (~ 70 km radius). Here, a 4-months survey was carried out during summertime to monitor planktonic microbial communities of nine lakes located around Paris (Île-de-France, France) of comparable morphologies, yet distinct trophic statuses from mesotrophic to hypereutrophic. By thus minimizing the confounding factors, we investigated how trophic status could influence prokaryotic community structures (16S rRNA gene sequencing) and functions (shotgun metagenomics). These freshwater lakes harbored highly distinct and diverse prokaryotic communities, and their trophic status appears as the main driver explaining both differences in community structure and functional potential. Although their gene pool was quite stable and shared among lakes, taxonomical and functional changes were correlated. According to trophic status, differences in phosphorus metabolism-related genes were highlighted among the relevant functions involved in the biogeochemical cycles. Overall, hypereutrophic lakes microbiomes displayed the highest contrast and heterogeneity over time, suggesting a specific microbial regime shift compared to eutrophic and mesotrophic lakes.</div
Development and Validation of a Liquid Chromatography High‐Resolution Mass Spectrometry Method for Blood Desmopressin Quantification and Its Application in Hemophilia A Patients
No full textInternational audienceDesmopressin (DDAVP), which indirectly increases Coagulation Factor VIII concentrations in the blood, is a common treatment for bleeding disorders such as von Willebrand disease or hemophilia A. However, DDAVP exhibits significant variability in response due to interindividual differences in pharmacokinetics. Consequently, exploring its pharmacokinetics is of primary importance to better understand the relationship between DDAVP administration and therapeutic outcomes. To that end, the measurement of DDAVP concentration is essential. This article describes the development and validation of a liquid chromatography method coupled with high‐resolution mass spectrometry detection for quantifying DDAVP in human plasma. After sample pretreatment involving protein precipitation followed by solid‐phase extraction, quantification was based on the four most intense isotopes, utilizing targeted single ion monitoring, with a method range of 20–2000 pg.mL−1. For the four QC levels, accuracy and precision for both inter‐ and intra‐assay measurements were below 11.6% and 13.8%, respectively, meeting FDA recommendations. After validation, this method was applied to a cohort of 10 patients with a deficiency in Coagulation Factor VIII, who received 0.3 μg.kg−1 of desmopressin acetate. The mean volume of distribution at steady state was 18.8 L (CV% 26.7), the mean clearance was 7.8 L.h−1 (CV% 25.1), and the mean half‐life was 1.8 h (CV% 14.7). Offering valuable insights into the pharmacokinetics of DDAVP, this method will be useful for further studies and holds promise for optimizing treatment regimens in this patient population
