Publications scientifiques de l'Université de Reims Champagne-Ardenne
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Le défi de la mobilité interne à l’hôpital public: L’exemple d’un projet piloté par le management intermédiaire
No full textInternational audienceLa mobilité interne est devenue un dilemme récurrent pour les cadres de santé : source de tensions, parfois vécue comme une forme de maltraitance managériale, elle apparaît essentielle à la continuité des soins. Dans l’étude présentée, une cadre supérieure de santé s’est saisie de la question en considérant à la fois le bien-être des soignants et la qualité des soins
Strong earthquakes on the French-Italian Mediterranean Riviera
No full textInternational audienceWe present a joint analysis of all available seismological, geodetic and geological data to assess seismic hazard along the vulnerable French-Italian Riviera. This is achieved by discussing the most likely scenario and quantifying recurrence times for strong earthquakes. The most destructive earthquake known in the area (1887, Mw ~ 6.8) occurred offshore on the Ligurian Fault. This event is typical of strong but sporadic earthquakes that can provide valuable insights into the behavior of low-slip-rate faults. Given the uncertainties on each type of data, the results of the different approaches indicate a wide range of recurrence times for such an earthquake, from 607 to 15,969 yr. Considering the most probable values refines this range to 2353-9484 yr. Variations in seismicity rate associated with changes in geodynamic and environmental conditions are also discussed. Since the 1887 earthquake only ruptured the central part of the Ligurian Fault, the largest future hazard is posed by the adjacent fault segments, which could generate an event of similar magnitude
Improving CTVboost delineation after preoperative systemic therapy in breast cancer using deformable PET/CT registration
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Integration of experimental protocols in Galaxy platform to facilitate the FAIRification of data
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Targeted Photodynamic Therapy for Pancreatic Cancer: Recent Innovations from Fundamentals to <i>In Vivo</i> and Clinical Applications (2020-2025)
No full textInternational audiencePhotodynamic Therapy (PDT) is a clinically-approved medical modality to treat different types of localised conditions such as cancer, infections or skin conditions. Pancreatic cancer (PC) is a deadly cancer displaying a dramatic overall prognosis that has barely improved in decades as the majority of PC patients are diagnosed at a locally advanced or metastatic stage and cannot benefit of surgical resection which is the only curative treatment, the overall 5-year survival rate remains extremely low. Thus, finding new therapies for non-metastatic PC to improve local control as a bridge to surgical resection and improve survival outcomes remains a huge challenge. In this context, PDT could be an interesting option. This review will focus on the use of PDT with targeted photosensitisers or nanoparticles to treat PC in recent studies (2020-2025) from in vitro to in vivo experiments and clinical applications
Crises et Reconstruction : Reims pendant la Troisième République, la Grande Guerre et l’entre-deux-guerres
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Modeling and analysis of high-resolution H<sub>2</sub><sup>12</sup>CO spectra in the range 4450-5000 cm<sup>-1</sup>
No full textInternational audienceThis study presents modeling and analysis of the line positions and intensities of H₂CO in the 4450-5000 cm⁻¹ spectral region, recorded at a low temperature (160-166 K) at various pressures using a high-resolution Fourier transform spectrometer. The calculations are based on a series of numerical block-diagonalization procedures applied to the nuclear-motion Hamiltonian, which was constructed from our ab initio potential energy and dipole moment surfaces, resulting in a new effective model for successive rovibrational polyads. Over 4600 assigned transitions were included in the empirical optimization of the model parameters using observed line positions. The fitting process for line intensities involved about 3300 transitions. The root-meansquare (RMS) deviation for line positions in the studied range is 0.00094 cm-1, while the RMS deviation for the line intensities is 10.18%. New theoretical predictions for the isotopic species H213C16O, H212C18O, for the band origins are reported. The improved line list contains 25725 transitions, including both experimentally measured and calculated lines. Validations of the new list are discussed, using comparisons of the transmittance simulation versus our high-resolution experimental spectra at T = 160-166 K and of cross-section simulations at T = 296 K versus medium-resolution PNNL observations
Outcomes of Second Breast-Conserving Surgery Without Reirradiation for Breast Tumor Recurrence
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La place de l’UE dans le commerce mondial de produits agricoles et agroalimentaires
No full textInternational audienceWorld trade in agricultural and agri-food products has been growing steadily for several decades under the influence of increasing food demand, particularly in Asia and Africa, and an unequal territorial distribution of agronomic and productive potential. With a trade balance of 39 billion euros in 2024, the European Union (EU-27) has become a major player in this trade. Using information from two databases (Baci and Comext), this article presents an analysis of the main trade dynamics observed in this sector over just over two decades.Le commerce mondial des produits agricoles et agroalimentaires connaît un développement soutenu depuis plusieurs décennies sous l'influence d'une demande alimentaire en croissance, notamment en Asie et en Afrique, et d'une répartition territoriale inégale des potentiels agronomiques et productifs. Avec un solde commercial de 39 milliards d'euros en 2024, l'Union européenne (UE-27) est devenue un acteur majeur de ce commerce. En utilisant les informations issues de deux bases de données (BACI et COMEXT), cet article présente une analyse des principales dynamiques commerciales observées dans ce secteur sur un peu plus de deux décennies
L’impact des changements climatiques sur la pathogénèse bactérienne en France
No full textLe système Terre subit des changements climatiques depuis sa création, en passant par des périodes glacières froides et chaudes. Cependant, depuis les années 1950 et le début de l’industrialisation, la pollution induite par l’Homme a conduit à une modification du climat et a un impact sur les populations humaines, animales et microbiotiques. Plusieurs bactéries tels que Salmonella spp., Vibrio spp. et Legionella spp., qui sont sensibles à ces changements, vont alors subir des modifications de leurs pathénogénèse. Elles vont s’adapter et peuvent alors entrainer une augmentation des infections et de leurs gravités. Pour limiter ces infections, la France et les pays du Monde tentent d’adopter des solutions de santé publique dans le but de freiner ces changements climatiques et donc leurs impacts sur les bactéries mises en causes dans la montée des infections