Repositorio Digital Universidad Simón Bolívar
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Responsabilidad social de las empresas carboníferas: percepción de los pobladores del municipio Chiriguaná, Colombia
No full textEl propósito de la investigación, fue analizar la responsabilidad social de las empresas
carboníferas según la percepción de los pobladores del municipio Chiriguaná, el Cesar,
Colombia, utilizando el enfoque cualitativo combinando la tradición fenomenológica,
entrevistas no estructuradas y revisión documental, derivando en la hermenéutica de los
resultados, encontrando que en la percepción de los entrevistados las empresas están
desvinculadas de la realidad de la población, así sus acciones de responsabilidad social
no satisfacen las verdaderas necesidades existentes. Se concluye que las empresas
deben realizar un diagnóstico exhaustivo de las necesidades de la población, en materia
de responsabilidad social, y con base a ello implementar acciones que las satisfagan
adecuadamente, mejorando la percepción que tienen los pobladores del municipio
Chiriguaná sobre estas empresasThe purpose of the research was to analyze the social responsibility of the coal
companies according to the perception of the inhabitants of the municipality of Chiriguaná,
Cesar, Colombia, using the qualitative approach combining the phenomenological
tradition, unstructured interviews and documentary review, deriving in the hermeneutics
of the results, finding that in the perception of the interviewees the companies are
disconnected from the reality of the population, thus their actions of social responsibility
do not satisfy the real existing needs. It is concluded that companies must make a
thorough diagnosis of the needs of the population, in terms of social responsibility, and
based on this implement actions that adequately meet them, improving the perception
that the inhabitants of the municipality Chiriguaná have about these companie
Method to identify and predict suicide risk profiles of adolescents using techniques of conglomerate analysis and artificial neural network
No full textEn este trabajo de investigación, se presenta un método para
identificar y pronosticar perfiles de riesgo suicida en adolescentes
a partir del caso de estudio de estudiantes de secundaria
de escuela pública del departamento del Atlántico.
Como fundamento teórico se utilizó la literatura asociada a
la evaluación del riesgo suicida, el análisis de conglomerados
y las redes neuronales artificiales. Para lo anterior, se
tomó información relacionada con los factores de riesgo suicida
desesperanza, ideación, aislamiento y apoyo familiar de
una muestra de 119 estudiantes adolescentes de los grados
noveno al undécimo del departamento del Atlántico. Como
resultado se desarrolló un método para identificar, valorar y
pronosticar perfiles de riesgo suicida en adolescentes. Se
concluye que el análisis de conglomerados mostró condiciones
favorables para clasificar 4 perfiles característicos de
riesgo suicida y las redes neuronales artificiales capacidad
de pronosticar con una probabilidad del 95,5% de clasificación
correcta.This article presents the profiles of suicide risk in 119 adolescent
high school students of public schools of the department
of Atlántico. As a theoretical basis, the literature associated
with the evaluation of suicide risk, the analysis of conglomerates
and the artificial neural networks were used. For the
above, information was taken related to suicidal risk factors,
hopelessness, ideation, isolation and family support. As a result,
a method was developed to identify, assess and predict
suicide risk profiles in adolescents. It is concluded that the
cluster analysis showed favorable conditions to classify 4
characteristic profiles of suicide risk and artificial neural networks
with a capacity to predict with a 95.5% probability of
correct classification
Dynamic Effects of CYP2D6 Genetic Variants in a Set of Poor Metaboliser Patients with Infiltrating Ductal Cancer Under Treatment with Tamoxifen
No full textBreast cancer is a group of multigenic diseases. It is the most common cancer diagnosed among women worldwide and is often treated with tamoxifen. Tamoxifen is catalysed by cytochrome P450 2D6 (CYP2D6), and inter-individual variations in the enzyme due to single nucleotide polymorphisms (SNPs) could alter enzyme activity. We evaluated SNPs in patients from Colombia in South America who were receiving tamoxifen treatment for breast cancer. Allelic diversity in the CYP2D6 gene was found in the studied population, with two patients displaying the poor-metaboliser phenotype. Molecular dynamics and trajectory analyses were performed for CYP2D6 from these two patients, comparing it with the common allelic form (CYP2D6*1). Although we found no significant structural change in the protein, its dynamics differ significantly from those of CYP2D6*1, the effect of such differential dynamics resulting in an inefficient enzyme with serious implications for tamoxifen-treated patients, increasing the risk of disease relapse and ineffective treatment
Gestión energética en el sector salud en Colombia: un caso de desarrollo limpio y sostenible
No full textEl objetivo del presente artículo es analizar la gestión energética desde la mirada del desarrollo limpio y sostenible en las instituciones prestadoras de servicios de salud en Colombia. El estudio es realizado a través de un enfoque cualitativo con un método de revisión documental de la literatura con información de artículos científicos de los últimos 8 años, ubicados en bases de datos especializadas, esto con el propósito de explorar avances en esta materia a nivel mundial y determinar los aportes que pudiesen ser replicados en el país. Los resultados evidencian la existencia de un respaldo institucional para el desarrollo de la gestión energética, así como, la definición de diversas alternativas y áreas de intervención en función de los diferentes servicios prestados. Se concluye que las fuentes de mayor consumo energético están concentradas en climatización e iluminación, y que las estrategias para reducir costos se relacionan con la optimización de contratos de suministro de energía e instalaciones de centros hospitalarios.The objective of this article is to analyze energy management from the perspective of clean and sustainable development in institutions that provide health services in Colombia. The study is carried out through a qualitative approach with a method of documentary review of the literature with information from scientific articles of the last 8 years, located in specialized databases, this with the purpose of exploring advances in this area worldwide and determine the contributions that could be replicated in the country. Results show that there is evidence of institutional support for the development of energy management, as well as the definition of various alternatives and areas of intervention depending on the different services provided. It is concluded that the sources of greatest energy consumption are concentrated in air conditioning and lighting, and that strategies to reduce costs are related to the optimization of energy supply contracts and hospital facilities
Peripheral Neuropathy and foot ulceration risk according International Working Group on the Diabetic Foot criteria
No full textObjetivo: evaluación de la presencia de Neuropatía Diabética y de riesgo de úlcera en pie según los criterios de la IWGDF. Materiales y Método: se realizó un estudio descriptivo
trasversal multicéntrico en una muestra de 100 pacientes diabéticos en tres centros de salud ubicados en Puerto Ordaz, estado Bolívar, Venezuela, seleccionados mediante
muestro no probabilístico intencional Los datos obtenidos fueron clasificados utilizando la escala de la IWGDF. Los datos obtenidos fueron analizados mediante el Paquete Estadístico para las Ciencias Sociales (SPSS) v.19 (SPSS IBM Chicago, IL). Resultados: el sexo femenino fue más afectado representando un 64% del total de pacientes evaluados. El 54% de la población estuvo en edades comprendidas entre los 61 y 75 años. Solo el 31% eran fumadores y 26% consumían alcohol, con una duración de la diabetes desde su diagnóstico de 13,6 años. El IMC en promedio fue de 29,15 Kg/m2. En relación al riesgo de ulceración según la IWGDF, el 74% presentaron un riesgo alto y 16% un riesgo máximo, que sumados alcanzaron un 90% de toda la población con elevado riesgo de sufrir úlcera en pie. La sensibilidad superficial abolida en riesgo alto fue del 51,4% y 93,8% en los pacientes con riesgo máximo. La Enfermedad vascular venosa se presentó en el 68,9% de los pacientes con riesgo alto y arterial en un 50% de los pacientes en riesgo máximo p˂0,024. La sensibilidad profunda (vibratoria) estuvo ausente en el 85,1% en pacientes con riesgo alto y en el 81,3% de los pacientes con riesgo máximo. p˂0,001 Conclusión: nuestros pacientes diabéticos tienen un elevado riesgo a sufrir úlceras en los pies.Objective: To evaluate the presence of diabetic neuropathy and foot ulcer risk according IWGDF criteria. Materials and Methods: A multicenter in a sample of 100 diabetic patients in three health centers located in Puerto Ordáz, Bolívar State, Venezuela, selected transverse descriptive study using non-probabilistic intentional sampling data obtained were classified using the scale IWGDF. The data obtained were analyzed using the Statistical Package for Social Sciences (SPSS) v.19 (IBM SPSS Chicago, IL). Results: Female sex was more affected 64%. 54% of the population is covered ages of 61-75 years. Only 31% were smokers and 26% consumed alcohol. Duration of diabetes 13.6 years on average, p <0.001. The average
BMI 29.15 p˂0,036. Regarding the risk of ulceration according to IWGDF, 74% are at high risk and 16% maximum risk; combined reach 90% of the population at high risk for foot ulcer. Intermittent claudication and its relationship with risk of ulceration 68.8% maximum risk. P 0.024. Surface sensitivity abolished in high-risk 51.4% and 93.8% ± 0,001 at maximum risk. Venous vascular disease and 68.9% high blood risk by 50% in maximum
risk p˂0,024. Deep sensitivity (vibratory) absent in 85.1% of patients with high risk and 81.3% in patients at highest risk. p˂0,001 Conclusion: our diabetic patients are at high risk to suffer from foot ulcers
Condición física y molestias osteomusculares según el índice de masa corporal de conductores de transporte urbano de Barranquilla, Colombia
No full textIntroduction: Sedentary work activities in urban transport drivers are associated with overweight and obesity, an increase in musculoskeletal discomfort related to work and a decrease in physical fitness.
Objective: To determine physical fitness and musculoskeletal discomfort in urban transport drivers from Barranquilla, Colombia, based on their body mass index (BMI). Material and Methods: Cross-sectional study conducted in 231
urban transport drivers. Healthy physical fitness and presence of musculoskeletal symptoms were measured using the AFISAL-INEFC
test battery and the Nordic Questionnaire developed by Kuorinka, respectively. Results: There were significant differences between drivers with normal
BMI and overweight/obese drivers in abdominal strength and endurance (21.4±8.9 vs. 19.6±8.8 stooped, p=0.04), flexibility (36.1±7.3 cm vs.
33.6±7.1 cm, p=0.02), and aerobic capacity (1537.5±704.8 meters vs. 1249.1±346.6 meters, p=0.0001). Increased frequency of musculoskeletal
discomfort was observed in subjects with BMI >25 kg/m2. Conclusions: Overweight and obesity are associated with poor physical fitness and the perception of musculoskeletal discomfort,
which has negative implications for the personal and occupational well-being of these workers, generating a burden for companies and the Colombian health system.Introducción. Las actividades laborales sedentarias de los conductores de transporte urbano están asociadas a sobrepeso, obesidad, incremento de molestias osteomusculares relacionadas con el trabajo y disminución de la condición física. Objetivo. Determinar la condición física y las molestias osteomusculares de conductores de transporte urbano de Barranquilla, Colombia, según
su índice de masa corporal (IMC). Materiales y métodos. Estudio transversal realizado en 231 conductores de transporte urbano. Se midió la condición física saludable y la presencia de síntomas musculoesqueléticos con la Batería AFISAL
INEFC y el Cuestionario Nórdico de Kuorinka, respectivamente. Resultados. Existen diferencias significativas entre los conductores con
IMC normal y aquellos con sobrepeso/obesidad en los valores de fuerza y resistencia abdominal (21.4±8.9 vs. 19.6±8.8 encorvadas, p=0.04), flexibilidad (36.1±7.3cm vs. 33.6±7.1cm, p=0.02) y capacidad aeróbica
(1537.5±704.8m vs. 1249.1±346.6m, p=0.0001). Se observó mayor frecuencia de molestias musculoesqueléticas en los sujetos con IMC >25
kg/m2. Conclusiones. El sobrepeso y la obesidad están relacionados con la baja condición física y la percepción de molestias osteomusculares, lo cual
tiene implicaciones negativas en el bienestar personal y laboral de estos trabajadores y constituye una carga para las empresas y el sistema de salud
Environments of deterritorialization and counter-hegemony: an existential look at the Pedagogy of meetings from the image-cinema
No full textSe pretende abrir la mirada a una construcción pedagógica que subvierta el aparente orden escolar que conmina tanto a los sujetos como a los saberes a ejercicios de transmisión donde la decisión del aprendiz esta reglado de antemano por una naturaleza hegemónica que controla el trámite de las enseñanzas. Por tanto, proponemos una pedagogía de los encuentros que mediada por la imagen-cine oriente praxis creativas que apelen a los sentidos inciertos e intempestivos de una experiencia desbordada estética y políticamente para privilegiar procesos existenciales de creación y resistencia. Así, damos curso a una expresión pedagógica siempre abierta que no restrinja, sino que estimule y comunique el tránsito de las diferencias.It is intended to open the eye to a pedagogical construction that subverts the apparent school order that brings both, subjects and knowledge to transmission exercises where the learner's decision is regulated beforehand by a hegemonic nature that controls the teaching process. Therefore, we propose a pedagogy of meetings, in which mediated by the image-cinema orientates creative praxis that appeals to the uncertain and untimely senses of an aesthetically and politically overflowed experience to privilege existential processes of creation and resistance. Thus, we give way to an always-open pedagogical expression that does not restrict but stimulates and communicates the transit of differences
Theory of the mind and cognitive functioning in people in reintegration processes in Colombia
No full textObjetivo: evaluar la Teoría de la Mente (ToM) y el funcionamiento cognitivo como componente de la cognición social en las personas en proceso de reintegración de la Agencia Colombiana
para la Reintegración (ACR) en el grupo territorial
Cesar-Guajira. Método: diseño de comparación multicaso, con una muestra de 3 hombres y 2 mujeres, con edades entre 23 y 43 años. Instrumentos aplicados: Addenbrooke’s Cognitive Examination Revisado – ACE R; Test de la Mirada (TdlM) de Baron-Cohen para Adultos; Escala de Ansiedad Manifiesta – AMAS Forma A en adultos y; Escala de Trauma de Davidson (DTS).
Resultados: se identificó que los sujetos presentaron déficit en ToM, ya que tuvieron dificultades para el reconocimiento de estados emocionales básicos y diferenciar estados emocionales complejos con distinta tonalidad afectiva. Conclusiones: se estableció que se requiere estudiar a profundidad el grado de relación entre alteraciones cognitivas, funcionamiento cognitivo, ToM y trauma para estimar gradualmente relaciones directas o nulas.Objective: to evaluate the Theory of the Mind (ToM) and cognitive functioning as a component of social cognition in people in the process of reintegration of the Colombian Agency for Reintegration (ACR) in the territorial group Cesar-Guajira. Method: multicase comparison design, with a sample of 3
men and 2 women, aged between 23 and 43 years. Applied instruments: Addenbrooke’s Cognitive Examination Revised - ACE R; Baron-Cohen Test of the Look (TdlM) for Adults; Manifest Anxiety Scale - AMAS Form A in adults and; Davidson Trauma Scale (DTS).
Results: it was identified that the subjects presented deficit in ToM, since they had difficulties for the recognition of basic emotional states and to differentiate complex emotional states with different affective tonality.
Conclusions: it was established that it is necessary to study in depth the degree of relationship between cognitive disorders, cognitive functioning, ToM and trauma to gradually estimate direct or null relationships
Testing GeoGebra as an effective tool to improve the understanding of the concept of limit on engineering students
No full textThe impact GeoGebra on the teaching of the concept of limit was analyzed. Two
groups of engineering students, studying differential calculus, served as control and test groups.
The traditional teaching, based on examples solved by hand, was given to the control group
while a series of activities involving the usage of the mathematical software GeoGebra were
applied in an attempt of improving the degree of assimilation on the concept of limits
Integrated analysis of microRNA regulation and its interaction with mechanisms of epigenetic regulation in the etiology of systemic lupus erythematosus
No full textThe aim of this study was to identity in silico the relationships among microRNAs (miRNAs)
and genes encoding transcription factors, ubiquitylation, DNA methylation, and histone
modifications in systemic lupus erythematosus (SLE). To identify miRNA dysregulation in
SLE, we used miR2Disease and PhenomiR for information about miRNAs exhibiting differential
regulation in disease and other biological processes, and HMDD for information about
experimentally supported human miRNA–disease association data from genetics, epigenetics,
circulating miRNAs, and miRNA–target interactions. This information was incorporated
into the miRNA analysis. High-throughput sequencing revealed circulating miRNAs associated
with kidney damage in patients with SLE. As the main finding of our in silico analysis of
miRNAs differentially expressed in SLE and their interactions with disease-susceptibility
genes, post-translational modifications, and transcription factors; we highlight 226 miRNAs
associated with genes and processes. Moreover, we highlight that alterations of miRNAs
such as hsa-miR-30a-5p, hsa-miR-16-5p, hsa-miR-142-5p, and hsa-miR-324-3p are most
commonly associated with post-translational modifications. In addition, altered miRNAs that
are most frequently associated with susceptibility-related genes are hsa-miR-16-5p, hsamiR-
374a-5p, hsa-miR-34a-5p, hsa-miR-31-5p, and hsa-miR-1-3p