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    The First Day’s Sun by Rabindranath Tagore, translated by Reza Haq

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    The First Day’s Sun: poem by Rabindranath Tagore, translated by Reza Ha

    Mortality and Memory in Kazuo Ishiguro’s Never Let Me Go

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    This article offers a reading of Kazuo Ishiguro’s Never Let Me Go as a meditation on human mortality. Set in an alternate England in the 1990s, the tragic love story revolves around the relationship between three human clones. The novel depicts the trio’s growing awareness of their fate and the way they cope with the pressure and anxiety consequent on understanding what lies before them. The article investigates how the situation reflects human beings’ confrontation with mortality. The discussion places an emphasis on the link between mortality and memory, which is posited as a function of the mind that can help assuage the psychic trauma of mortality in the story

    Novel missense mutation in the bZIP transcription factor, MAF, associated with congenital cataract, developmental delay, seizures and hearing loss (Aymé-Gripp syndrome)

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    This is an open access article. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated

    The barriers and facilitators that indigenous health workers experience in their workplace and communities in providing self-management support: a multiple case study

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    This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Background The inequality in health outcomes between Indigenous (Throughout the paper, the term Indigenous will be used to represent both Aboriginal Australians and Torres Strait Islander Australians.) and non-Indigenous Australians continues to be a major public health issue. Chronic conditions are responsible for the majority of the gap in life expectancy for this population. Evidence suggests that chronic condition management models focusing on self-management have led to improved health outcomes in Indigenous populations. The Flinders Closing the Gap Program (FCTGP) is a chronic condition care planning tool which aims to engage Indigenous people in self-managing their chronic conditions. Indigenous health workers (IHWs) can provide culturally appropriate self-management support; however there is paucity in current literature describing specific barriers and facilitators that they may experience when attempting to deliver this support. This study aimed to explore IHWs’ perceptions of the effectiveness and appropriateness of the FCTGP, as an evidence-based example of self-management support, and to explore the barriers and facilitators that IHWs experience in their workplace and communities in providing self-management support. Methods In-depth interviews were undertaken with five IHWs, drawn from five different states in Australia. Their selection was aided by key informants from the FCTGP training unit. Interviews were recorded and transcribed verbatim, and were analysed using thematic analysis. Results The following themes were identified. IHWs reported that the FCTGP was appropriate, flexible and acceptable in their communities. Facilitators included factors improving client and worker empowerment, and activities around sharing knowledge. Barriers included competing priorities that clients experience relating to social determinants of health, and negative experiences within mainstream health services. IHW burnout from time pressures, lack of support, and high staff turnover were also considered important barriers. Conclusions This study contributes an insight into the experiences of IHWs who are considered important stakeholders in implementation and sustainability of chronic condition management programs, including the FCTGP. Recommendations focus on supporting and supplementing the role of IHWs and identify the FCTGP as a facilitator in providing self-management support to a population with complex needs

    University lecturers' perspectives on initial teacher education for mental health promotion in schools

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    Copyright ©2017 Sense Publishers Reproduced with permission of the publisher

    Life at school and mental health from students' points of view: A study from Malta

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    Copyright © 2017 Sense Publishers Reproduced with permission of the publisher

    Role of the pharmacist for improving self-care and outcomes in heart failure

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    The final publication is available at Springer via http://dx.doi.org/10.1007/s11897-017-0323-2 This author accepted manuscript is made available following 12 month embargo from date of publication (Feb 2017) in accordance with the publisher’s archiving policyPurpose of Review This review highlights the current and emerging approaches for the role of the pharmacist for improving self-care and outcomes in heart failure management. Recent Findings Pharmacists are contributing to heart failure management in a variety of settings, including hospitals, clinics, and communities. Different interventions which may be mediated by the pharmacist include drug adherence, discharge counseling, medication reconciliation, telephone follow-up, and recommendation of evidence-based medicines. Summary Pharmacist engagement in heart failure management has demonstrated improved drug adherence, readmission rates, medication management, self-care ability, patient satisfaction, and heart failure knowledge. Some findings are mixed, especially for readmission rates. Improved medication management was reported in nearly all studies, despite significant heterogeneity in the models of care, patient populations, and study designs. This review highlights the requirement for large randomized trials with extended follow-up to confirm the impact of the role of the pharmacist in HF self-care, particularly through multidisciplinary-based interventions

    The excess burden of severe sepsis in Indigenous Australian children: can anything be done?

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    Schultz R. The excess burden of severe sepsis in Indigenous Australian children: can anything be done? Med J Aust 2017; 207 (1): 45. © Copyright 2017. The Medical Journal of Australia - reproduced with permission

    Urinary Extracellular Domain of Neurotrophin Receptor p75 as a Biomarker for Amyotrophic Lateral Sclerosis in a Chinese cohort

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    Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.To comprehensively assess whether p75ECD in urine could be a candidate biomarker for ALS evaluation. Urine samples were collected from 101 ALS patients, 108 patients with other neurological disease (OND) and 97 healthy controls. 61 ALS patients were followed up with clinical data including ALSFRS-r every 6 to 12 months, 23 ALS patients died and 17 ALS patients lost touch during follow up period. Enzyme-linked immunoassay was employed to determine urine p75ECD concentration. The ALSFRS-r was employed to assess the severity of ALS. The concentration of p75ECD in ALS was significantly higher than that of OND and CTRL (p < 0.001). Additionally, urine p75ECD concentrations in ALS-definite grade patients were significantly higher than that in ALS-probable grade and ALS-possible grade patients (p < 0.001). Higher urine p75ECD concentrations were correlated with increased clinical stage (p = 0.0309); urine p75ECD concentrations and ALSFRS-r were negatively correlated (p = 0.022); and urine p75ECD concentration in the fast-progressing ALS group was significantly higher than that in slow-progression (p = 0.0026). Our finding indicates that urine p75ECD concentration provides additional evidence for patients with clinically suspected ALS, and can be employed to evaluate ALS-severity

    Characteristics of active seawater intrusion

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    © 2017 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This author accepted manuscript is made available following 24 month embargo from date of publication (Aug 2017) in accordance with the publisher’s archiving policyThe inland migration of seawater in coastal aquifers, known as seawater intrusion (SWI), can be categorised as passive or active, depending on whether the hydraulic gradient slopes downwards towards the sea or the land, respectively. Despite active SWI occurring in many locations, it has received considerably less attention than passive SWI. In this study, active SWI caused by an inland freshwater head decline (FHD) is characterised using numerical modelling of various idealised unconfined coastal aquifer settings. Relationships between key features of active SWI (e.g., interface characteristics and SWI response time-scales) and the parameters of the problem (e.g., inland FHD, freshwater-seawater density contrast, dispersivity, hydraulic conductivity, porosity and aquifer thickness) are explored for the first time. Sensitivity analyses show that the SWI response time-scales under active SWI situations are influenced by both the initial and final boundary head differences. The interface is found to be steeper under stronger advection (i.e., caused by the inland FHD), higher dispersivity and hydraulic conductivity, and lower aquifer thickness, seawater density and porosity. The interface movement is faster and the mixing zone is wider with larger hydraulic conductivity, seawater-freshwater density difference, and aquifer thickness, and with lower porosity. Dimensionless parameters (Peclet number and mixed convection ratio) from previous steady-state analyses offer only limited application to the controlling factors of passive SWI, and are not applicable to active SWI. The current study of active SWI highlights important functional relationships that improve the general understanding of SWI, which has otherwise been founded primarily on steady-state and passive SWI

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