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Caffeine doses of 3 mg/kg increase unilateral and bilateral vertical jump outcomes in elite traditional Jiu-Jitsu athletes
No full textCaffeine increases vertical jump, although its effects on kinetics and kinematics during different phases of bilateral and unilateral jumps remain unclear. The aim of this study was to identify the effects of 3 mg/kg on kinetic, kinematic and temporal variables in the concentric and eccentric phases of bilateral and unilateral countermovement jumps. A total of 16 Spanish national team traditional Jiu-Jitsu athletes took part in two experimental trials (3 mg/kg caffeine or placebo) in a randomized, double-blind crossover study. Sixty minutes after ingestion, bilateral and unilateral jumps were performed on a force platform. Compared to the placebo, caffeine increased bilateral jump height (p = 0.008; Δ% = 4.40), flight time (p = 0.008; Δ% = 2.20), flight time:contraction time (p = 0.029; Δ% = 8.90), concentric impulse (p = 0.018; Δ% = 1.80), peak power (p = 0.049; Δ% = 2.50), RSI-modified (p = 0.011; Δ% = 11.50) and eccentric mean braking force (p = 0.045; Δ% = 4.00). Additionally, caffeine increased unilateral RSI-mod in both legs (Left: p = 0.034; Δ% = 7.65; Right: p = 0.004; Δ% = 11.83), left leg flight time (p = 0.044; Δ% = 1.91), left leg jump height (p = 0.039; Δ% = 3.75) and right leg FT:CT (p = 0.040; Δ% = 9.72). Caffeine in a dose of 3 mg/kg BM in elite Jiu-Jitsu athletes is a recommended ergogenic aid as it increased performance of bilateral and unilateral vertical jumps. These increases were also accompanied by modified jump execution during the different phases of the countermovement prior to take-off
Lack of Parkinsonian Pathology and Neurodegeneration in Mice After Long-Term Injections of a Proteasome Inhibitor in Olfactory Bulb and Amygdala
Get PDFProteinaceous inclusions, called Lewy bodies (LBs), are used as a pathological hallmark for Parkinson’s disease (PD). Recent studies suggested a prion-like spreading mechanism for α-synucleinopathy where early neuropathological deposits occur, among others, in the olfactory bulb (OB) and amygdala. LBs contain insoluble α-synuclein and many other ubiquitinated proteins, suggesting a role of protein degradation system failure in PD pathogenesis. Therefore, we wanted to study the effects of a proteasomal inhibitor, lactacystin, on the aggregability and transmissibility of α-synuclein in the OB and amygdala. We performed injections of lactacystin in the OB and amygdala of wild-type mice. Motor behavior, markers of neuroinflammation, α-synuclein, and dopaminergic integrity were assessed by immunohistochemistry. Overall, there were no differences in the number of neurons and α-synuclein expression in these regions following injection of lactacystin into either the OB or amygdala. Microglial and astroglial labeling appeared to be correlated with surgery-induced inflammation or local effects of lactacystin. Consistent with the behavior and pathological findings, there was no loss of dopaminergic cell bodies in the substantia nigra and terminals in the striatum. Our data showed that long-term lactacystin injections in extra nigrostriatal regions may not mimic spreading aspects of PD and reinforce the special vulnerability of dopaminergic neurons of the substantia nigra pars compacta (SNc)
Competencias y habilidades para el desarrollo de la práctica docente en escuelas infantiles rurales multigrado. Estudio comparado entre México y España
Get PDFEl éxito de la enseñanza multigrado demanda que los docentes que se desenvuelven en estos centros escolares cuenten con los conocimientos y habilidades que les permitan maximizar las posibilidades pedagógicas que esta modalidad educativa ofrece. En México y España, la existencia de escuelas multigrado en el nivel de Educación Infantil establece la necesidad de contar con docentes capaces de responder a los desafíos contextuales, sociales y culturales que predominan en dichos centros.
El presente estudio explora, a través del método de Educación Comparada, de corte cualitativo, el discurso y la práctica docente de profesores multigrado de Educación Infantil en México y España. Al compartir ambos países características similares en el objeto de estudio, se permite su análisis desde una perspectiva internacional y comparatista. El uso de técnicas e instrumentos de corte cualitativo para la recogida y análisis de datos posibilitaron el desarrollo de un estudio descriptivo e interpretativo, cuyos rasgos se centran en explicar y representar los hechos que acontecen en estos centros, desde su propio contexto.
La aplicación de entrevistas estructuradas y la realización de observaciones a jornadas educativas durante los cursos escolares 2017/2018 y 2018/2019, en ocho centros educativos en México y ocho unidades de dos Centros Rurales Agrupados en España, permitieron explorar la percepción y la práctica de 16 profesores multigrado, ocho por cada país, en torno a la formación docente inicial y continua recibida para su desempeño docente multigrado.
Se analizó también el discurso del profesorado sobre los conocimientos con los que cuentan para la organización de los elementos que conforman la didáctica multigrado y el uso que de estos hacen (enfoques de enseñanza y agrupación, uso del tiempo, de los recursos didácticos y del espacio escolar). Asimismo, a partir del análisis de contenido, se estudiaron los lineamientos curriculares, legales, nacionales e institucionales de las licenciaturas en Educación preescolar y en Educación preescolar bilingüe en México y del Grado de Magisterio infantil en España, permitiendo identificar la medida en que las autoridades educativas han considerado la formación del profesorado en el ejercicio de su función para el desempeño docente en el contexto multigrado.
El cruce de la información obtenida de las observaciones y las entrevistas, así como del análisis documental de los lineamientos curriculares legales, nacionales e
institucionales del grado de Magisterio infantil, permitieron identificar las necesidades formativas del profesorado y las áreas de oportunidad pendientes de abordar desde la formación docente en ambos países. Una vez concluido el estudio, se plantean una serie de aspectos prácticos que los sistemas educativos de ambos países podrían implementar para posibilitar la organización efectiva de los procesos educativos en relación con los aspectos culturales y sociales que la escuela multigrado representa
“Prólogo y selección” en 'Aquí termina y aquí empieza una historia de amor. Antología poética (2019/1968)'
No full textMi trabajo presenta una selección de la poesía del merideño Enrique Hernández D’Jesús, de sus 22 libros más significativos, comenzando en 1968 con “Muerto de risa” y finalizando en 2017 con un texto inédito. En el prólogo demuestro que el autor prefiere la estructura en analepsis y que juega a visiones conectadas, tiempos paralelos, flashbacks y simultaneidades entre presente y pasado. El estudio aborda esta original poética en diálogo con André Breton, la Generación Beat, la Vanguardia Hispanoamericana y esa magnética tradición de la poesía venezolana que invoca neobarroco, telurismo y realismo mágico. El análisis revela también ritmos, estéticas y temáticas precolombinas, junto a elementos del simbolismo europeo
Impacto del estado funcional del Core en la prevención y readaptación de lesiones de hombro y el rendimiento en nadadores. Revisión sistemática
No full textAl igual que el estado
funcional del Core es una pieza fundamental
en determinadas lesiones más distales al
Core en el los Miembros Inferiores y en la
mejora del rendimiento en numerosos
deportes, ¿Por qué no se extrapolan estos
beneficios a los deportes que involucran
constantemente los Miembros Superiores, en
concreto la natación y la implicación del
hombro en éste deporte?.
Por tanto en los últimos años han surgido
nuevas investigaciones que tienen en cuenta
esta relación causal.
La siguiente revisión sistemática recoge los
proyectos de investigación que estudian el
estado funcional del Core respecto a la
presencia de lesiones en el complejo del
hombro y respecto al rendimiento en
natación
Therapeutic Drug Monitoring of Antifungal Drugs: Another Tool to Improve Patient Outcome?
Get PDFIntroduction: This study aimed to examine the relationship among adequate dose, serum concentration and clinical outcome in a non-selected group of hospitalized patients receiving antifungals.
Methods: Prospective cross-sectional study performed between March 2015 and June 2015. Dosage of antifungals was considered adequate according to the IDSA guidelines, whereas trough serum concentrations (determined with HPLC) were considered adequate as follows: fluconazole > 11 µg/ml, echinocandins > 1 µg/ml, voriconazole 1-5.5 µg/ml and posaconazole > 0.7 µg/ml.
Results: During the study period, 84 patients (65.4% male, 59.6 years) received antifungals for prophylaxis (40.4%), targeted (31.0%) and empirical therapy (28.6%). The most frequent drug was micafungin (28/84; 33.3%) followed by fluconazole (23/84; 27.4%), voriconazole (15/84; 17.9%), anidulafungin (8/84; 9.5%), posaconazole (7/84; 8.3%) and caspofungin (3/84; 3.6%). Considerable interindividual variability was observed for all antifungals with a large proportion of the patients (64.3%) not attaining adequate trough serum concentrations, despite receiving an adequate antifungal dose. Attaining the on-target serum antifungal level was significantly associated with a favorable clinical outcome (OR = 0.02; 95% CI 0.01-0.64; p = 0.03), whereas the administration of an adequate antifungal dosage was not.
Conclusions: With the standard antifungal dosage, a considerable proportion of patients have low drug concentrations, which are associated with poor clinical outcome.
Keywords: Antifungals; Azoles; Clinical outcome; Echinocandins; Invasive fungal infections
Impulsivity and the Experience of Desire in the Choice of Erotic Stimuli
Get PDF(1) Background: the relationship between erotic desire and personality factors is still relatively understudied. (2) Objective: to study the influence of the experience of desire, as well as impulsivity in the choice of videos, as the behavioral variable in the experimental trial. (2) Method: the sample consisted of 48 adult subjects, who took part in an experimental study that involved watching videos. (3) Results: the linear regression analysis revealed that the behavior involved in choosing videos is predicted by the sexual desire felt at the time of the trial, and not by stable personality factors, such as impulsivity or general self-report levels of sexual desire. (4) Conclusion: it is observed that the specific moment or situation and the behavior have a bigger impact on the erotic desire experienced at the time of the test than certain personality traits, as well as the previous and habitual levels of erotic desire of which an individual reports
Individual differences in anger and displaced aggression: the role of metacognitive beliefs and anger rumination.
No full textMetacognitive model is a theoretical approach aimed to explain emotion dysregulation and others emotion-related issues, such anger, and aggressive behavior. From this model, people having higher maladaptive metacognitive beliefs (e.g., “I can't control my thoughts”) are more likely to activate and maintain anger rumination and, in turn, to experience higher levels of anger and to act aggressively. Preliminary evidence shows the role of metacognitive beliefs on anger rumination and anger levels, whereas no studies have examined its association with aggressive behavior. This study first examined the associations between metacognitive beliefs, anger rumination, anger levels, and the propensity to engage in displaced aggression, and second, the mediation role of anger rumination in the relations among metacognitive beliefs and anger and displaced aggression. Participants were 947 students and non-students from general population recruited in two different countries (Australia and Spain). Correlational analyses revealed a similar pattern of results in the Australian and Spanish sample, with participants having dysfunctional metacognitive beliefs also showing higher anger rumination, higher levels of anger and a higher tendency to act aggressively. Structural equation analyses revealed the associations of metacognitive beliefs with anger levels and displaced aggression was fully mediated by anger rumination in both samples. These results suggest that metacognitive beliefs should be considered in comprehensive models and in the therapy of anger problems and aggression
Emotional regulation processes: influence on pain and disability in fibromyalgia patients
No full textObjectives: Fibromyalgia (FM) is a chronic syndrome characterised by widespread musculoskeletal pain associated with other symptoms, including psychological distress. While negative mood (anxiety, depression, and anger) has been widely explored in FM, few studies have investigated emotional dysregulation. Our purpose was to evaluate problems in the processes of emotional regulation and to explore their influence on the severity of pain and disability.
Methods: Emotional regulations, anxiety, depression, anger, pain and disability were evaluated in 47 FM patients and 47 healthy subjects. Regression analyses were performed to evaluate the role that emotional regulation processes have on pain severity and disability of FM patients.
Results: Results showed that although FM patients do not differ in terms of the attention paid to their emotional states, FM patients had greater difficulties in the emotional regulation process. In addition, emotional rejection and interference are two variables that influence the pain severity and disability.
Conclusions: FM patients need to be trained in strategies for regulating their emotions, in order to achieve a reduction in negative mood states, as well as their impact in pain and disability
Proyecto de Nutrición 7ª Grado
Get PDFReconociendo las conexiones entre la salud y el
rendimiento académico, así como la importancia de
las prácticas escolares basadas en evidencia, el
colegio SEK Ciudalcampo se asoció con Stephen
Heppell, UCJC y Catergest en un proyecto de interés
mutuo: establecer hábitos alimenticios saludables
que tengan un efecto positivo en el aprendizaje.
Un grupo de estudiantes apasionadas por el proyecto
lanzó el Brain Food Group y trabajó en varias
iniciativas para correr la voz sobre la alimentación
saludable, específicamente al agregar 20 "alimentos
para el cerebro" a nuestras dietas. Este libro de recetas
fue desarrollado por ellas para que pudieran
promover hábitos alimenticios saludables.
¡Esperamos que disfrutes el libro!
Bajo el liderazgo del Dr. Juan Carlos Segovia de la UCJC y
el Proyecto NARA, el Grupo de “Brain Food” elaboró 20
“Alimentos Cerebrales” con evidencia científica de poseer
un efecto positivo en el cerebro y el aprendizaje. Basándose
en la revisión de la literatura, que se puede encontrar en el
apéndice, los siguientes alimentos fueron acuñados como
"Alimentos para el cerebro"Fundación Felipe Segovi