128119 research outputs found

    Learning: adult education, training, and new technologies

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    Lifelong learning (LLL) is an essential tool for addressing the challenges posed by the complexity of modern life. However, it is crucial to reflect on what knowledge, skills, attitudes, and values are necessary to navigate today's world, and to clarify what we mean by "learning" and its objectives. Answers to these questions require a pedagogical reflection aimed at defining an ed- ucation that enables learning as an active and generative process of constructing and transforming knowledge and skills. Furthermore, the impact of technologies and artificial intelligence on what and how we learn must be acknowledged, as they significantly influence the educational process

    Coronary CT Angiography in the Emergency Department: State of the Art and Future Perspectives

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    About 5% of annual access to emergency departments (EDs) and up to 25–30% of hospital admissions involve patients with symptoms suggestive of acute coronary syndrome (ACS). The process of evaluating and treating these patients is highly challenging for clinicians because failing to correctly identify an ACS can result in fatal or life-threatening consequences. However, about 50–60% of these patients who are admitted to the hospital because of chest pain are found to have no ACS. Coronary computed tomographic angiography (CCTA) has emerged as a proposed new frontline test for managing acute chest pain in the ED, particularly for patients with low-to-intermediate risk. This narrative review explores the potential of adopting an early CCTA-based approach in the ED, its significance in the era of high-sensitivity troponins, its application to high-risk patients and its prognostic value concerning atherosclerotic burden and high-risk plaque features. Additionally, we address clinical and technical issues related to CCTA use for triaging acute chest pain in the ED, as well as the role of functional testing. Finally, we aim to provide insight into future perspectives for the clinical application of CCTA in the ED

    Improving the quality of whole-plant corn silage in the top layer of a silo by using an inoculant in combination with sodium benzoate

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    The aim of this study was to determine the effect of a commercial bacterial inoculant in combination with sodium benzoate on aerobic spoilage of whole-plant corn silage (WPCS) in the upper layer of a bunker silo. More specifically, we compared control silage (CTR) that was treated with water alone and experimental silage (OS) that was inoculated with SiloSolve® OS (a combination of Enterococcus faecium [DSM 22502/1k20602], Lactococcus lactis [DSM 11037/1k2081], and Lactiplantibacillus plantarum [DSM 16568/1k20720]) in combination with sodium-benzoate. After harvest, 1000 kg of freshly chopped corn was divided into two equal groups (OS and CTR), followed by homogenization with a pitchfork. For each group, 12 silo-NET bags (SNBs; high density polyethylene, 27 ×120 cm, 200 μm mesh pores) were filled with approximately 5.5 kg of freshly chopped forage, and then buried at a depth of 0.30 m in different regions of a bunker silo (26 m long, 8.5 m wide, 3.5 m high) for 98, 142, or 217 days. The bunker silo was divided lengthwise into two equal parts, and a 2-m buffer zone separated the CTR group and the OS group. After application of each treatment, the SNBs were removed from the ensiled mass, weighed, and mixed thoroughly, followed by measurement of chemical, fermentative, and microbiological parameters. The OS group had a decreased loss of dry matter (5.3 ± 4.72 vs. 12.5 ± 4.72 g/kg DM, P < 0.05), greater aerobic stability (302.0 ± 64.5 vs. 225.7 ± 64.5 h, P < 0.05), a lower count of yeasts (2.33 ± 0.84 vs. 3.74 ± 0.84 log10[CFU/g], P < 0.05), and a lower count of molds (2.24 ± 0.50 vs. 3.12 ± 0.50 log10[CFU/g], P < 0.05). During the feed-out phase, the temperature of the core and top layer of the bunker and the amount of WPCS waste were determined for the two groups. The temperature was consistently lower in the OS group, and the total amount of waste (2.01 % of total WPCS) was 43 % lower in the OS group. We conclude that treatment of the top layer of WPCS in a bunker silo with a commercial inoculant and sodium benzoate can decrease spoilage and increase the economic value of silage

    Domenico e Ugo d'Ostia

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    Vengono riconsiderate le testimonianze circa gli incontri tra Domenico e il cardinale Ugo d'Ostia tra 1215 e 1221, al fine di mettere in luce la stretta collaborazione presto instauratasi tra Domenico e la curia romana. Egli seppe infatti dare una risposta alla questione della regolarizzazione della vita religiosa femminile e, con la scelta di dedicarsi alla predicazione, offrì il modello per l'istituzione di predicatori a sostegno dell'episcopato, come pure il IV concilio lateranense aveva stabilito. Il forte legame instauratori tra DOmenico e il cardinale Ugo fu suggellato dalla presenza di quest'ultimo a Bologna sia durante la malattia di Domenico sia addirittura in occasione delle sue esequie.The evidence concerning the meetings between Dominic and Cardinal Hugo of Ostia between 1215 and 1221 is reconsidered in order to highlight the close collaboration that soon developed between Dominic and the Roman Curia. He was able to provide an answer to the question of the regularisation of female religious life and, with his decision to devote himself to preaching, he offered a model for the establishment of preachers in support of the episcopate, as the Fourth Lateran Council had established. The strong bond established between Dominic and Cardinal Hugh was sealed by the latter's presence in Bologna both during Dominic's illness and even at his funeral

    Generalization and enhancement of the effects of an active placebo nasal spray on sadness

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    Introduction: The placebo effect, i.e., the psychobiological response arising from administering an inert treatment, influences various domains, such as pain perception and emotional regulation. Positive framing might enhance this effect. This study tested whether the effect of an active placebo (mimicking drug side effects to enhance treatment credibility) on is generalized between two different contexts of sadness induction and if positive framing of side effects enhances this effect. Methods: Ninety-six healthy participants were randomly assigned to one of three groups: Placebo+positive +positive framing (PPF), Placebo+standard +standard information (PSI), or no treatment control (NTC). Participants underwent a sadness induction protocol during an in-person lab session and a 20-min online follow-up at home six hours later. Primary outcome was self-reported sadness, secondary outcome was self-reported side effects. Results: Both the PPF and PSI groups showed a significant decrease in sadness compared to the NTC group after placebo administration during the lab session (p p < 0.001) and at follow-up (p p < 0.05). At follow-up, only the PPF group did not experience a significant increase in sadness. Positive framing did not improve side effect tolerability. Limitations: Self-reported measures introduce subjective bias. The sample restriction to healthy volunteers limits generalizability. The six-hour period may not capture clinically relevant long-term effects. Conclusions: The active placebo nasal spray effectively reduced sadness, with effects persisting for six hours and across different contexts. Positive framing did not enhance side effect tolerability but may have helped maintain effectiveness at follow-up. Further research is needed in clinical populations and to explore long-term effects

    EXPLORING SUPPLY CHAIN RESILIENCE ENHANCERS: A MULTI-LEVEL STUDY THROUGH SYSTEMIC REVIEW, CASE STUDIES, AND QUANTITATIVE ANALYSIS

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    The research thesis explores the complex and multifaceted concept of supply chain resilience (SCRES) through three research papers. The first paper assesses the current state of knowledge on SCRES enhancers and develops a comprehensive framework that includes three clusters of SCRES enhancers: SCRES capabilities, factors determined at the organizational level, and contingency factors. Additionally, it examines the role of supply chain management decisions in fostering a resilient supply chain. The second paper, using a case-based descriptive research approach, deepens the understanding of SCRES enhancers that effectively mitigate supply and demand risks, particularly within the agri-food sector. The third paper empirically investigates the relationship between SCRES and sustainability, evaluating the mediating role of investments in sustainability.La tesi di ricerca esplora il complesso e sfaccettato concetto di resilienza della supply chain (SCRES) attraverso tre articoli di ricerca. Il primo articolo indaga gli elementi che rafforzano la resilienza (SCRES enhancers) e sviluppa un framework articolato in tre categorie: le proprietà della resilienza (SCRES capabilities), i fattori determinati a livello organizzativo e i fattori contingenti. Inoltre, esamina il ruolo delle supply chain management decisions nello sviluppo di una supply chain resiliente. Il secondo articolo, attraverso un approccio di ricerca descrittivo basato su casi studio, approfondisce la comprensione dei fattori che potenziano la SCRES e che permettono di mitigare i rischi di approvvigionamento e domanda (supply and demand risks) nel settore agroalimentare. Il terzo articolo analizza empiricamente la relazione tra SCRES e sostenibilità

    Disabilità intellettiva e metacognizione

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    Indicazioni per sostenere gli alunni con disabilità intellettiv

    Have HR strategic partners left the building? The (new) role of HR professionals from a social-symbolic perspective

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    PurposeThis manuscript explores the evolving roles of HR professionals amidst global megatrends and organizational transitions, focusing on the Italian context, which has experienced disruptive adoption of new forms of work such as remote and hybrid work. In this challenging scenario, our research aims to uncover if and how HR professionals are transforming their roles or maintaining the status quo in navigating organizational changes, dealing with the upcoming working scenario, and challenging conventional perceptions of HR practitioners.Design/methodology/approachThe study employs the social-symbolic work lens, that contributes to a deeper understanding of how HR professionals work to construct organizational life, the identities of employees, and the societal norms and assumptions that provide the context for organizational action. This perspective highlights HR professionals' personal efforts, consisting of the emotional labor entailed in steering organizational transformations and, eventually, maintenance in a context where remote work has become prevalent. Data was collected through 16 online focus groups involving 76 HR professionals from Italian organizations.FindingsOur research offers two interrelated contributions to HR literature. First, we provide pieces of evidence on how HR practitioners act as agents of change in two emerging roles: the "Wannabe Hero" and the "Ordinary Hero". This challenges the prevailing rhetorical discourse about the so-called HR business partner. Secondly, we delve into the persistent obstacles that hinder HR professionals from making a substantial impact in addressing radical changes. These findings will provide useful insights into effectively engaging HR practitioners as agents of change in organizational transformation, shedding light on praxis, structures, and their emotional work.Originality/valueThe paper analyzes HR professionals' social-symbolic work, which offers an original contribution to the comprehension of the activities they carry on in practice and the emotions they have been experiencing. These influence both the way HR professionals play their role and the organizational and institutional environment

    Untargeted Salivary Metabolomics and Proteomics: Paving the Way for Early Detection of Periodontitis

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    Periodontitis is a chronic inflammatory disease that affects the supporting structures of the teeth and is a major cause of tooth loss worldwide. Early detection is critical to prevent disease progression and avoid irreversible tissue damage. Saliva, a non-invasive, easily accessible biological fluid, has emerged as a promising diagnostic tool for the early detection of various diseases, including periodontitis. This narrative review explores the potential of untargeted salivary metabolomics and proteomics in identifying biomarkers for the early diagnosis of periodontitis. Unlike traditional targeted approaches, untargeted analyses allow for the comprehensive exploration of a wide range of metabolites and proteins, without predefined hypotheses. This approach provides a deeper understanding of the disease’s biochemical landscape and can reveal novel biomarkers associated with the inflammatory processes of periodontitis. Besides making an early diagnosis, detecting specific biomarkers of periodontitis may enable the clinician to make an extremely personalized treatment plan. The review highlights key findings in the field, discusses the challenges and limitations of these techniques, and presents future perspectives on how salivary metabolomics and proteomics could revolutionize early diagnostic strategies in periodontal management

    Introduzione

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    Si tratta del decimo volume della collana voluta nel 2016 dall’Ufficio Nazionale per le comunicazioni sociali della Conferenza Episcopale Italiana e dal Centro di Ricerca sull’Educazione ai Media, all’Innovazione e alla Tecnologia (Cremit) dell’Università Cattolica del Sacro Cuore, in cui ogni anno sono pubblicati commenti di natura interdisciplinare al messaggio del Papa per la Giornata mondiale delle Comunicazioni Sociali. A condividere le loro suggestioni sul tracciato del testo della Giornata 2025, intitolato "Condividete con mitezza la speranza" sono accademici, studiosi, teologi, giornalisti, comunicatori, poeti, scrittori e quest’anno anche un Premio Nobel

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