Institutional Repository of Institute of Modern Physics, CAS
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金属掩模套版及使用方法
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<span style="text-indent: 24px;"> </span><span style="color: rgb(69, 69, 69); font-family: Arial, Helvetica, sans-serif; line-height: 21px; text-indent: 24px;">本发明涉及一种适用于新材料电子器件制作模板及模板的使用方法。一种金属掩模套版，包括掩模后挡板，还包括有用于测试各向异性材料的霍尔效应和电阻率的第一欧姆接触电极图形掩模板、用于测试各向同性材料的霍尔效应和电阻率的第二欧姆接触电极板、用于分析材料的电容电压特性的绝缘层图形掩模板和用于制作肖特基电极的肖特基接触电极图形掩模板。本发明还提供一种以上所述的金属掩模套版的使用方法。本发明的优点是：金属掩模套版结构简单，操作方便快捷，一次就可以在小尺寸样品上生长一批电极样品器件，同时能够方便高效的获得需要的器件尤其适合于材料辐照改性的研究。</span></div
Genistein Enhances the Radiosensitivity of Breast Cancer Cells via G(2)/M Cell Cycle Arrest and Apoptosis
No full textThe aim of the present study was to investigate the radiosensitizing effect of genistein, and the corresponding mechanisms of action on breast cancer cells with different estrogen receptor (ER) status. Human breast cancer cell lines such as MCF-7 (ER-positive, harboring wild-type p53) and MDA-MB-231 (ER-negative, harboring mutant p53) were irradiated with X-rays in the presence or absence of genistein. Cell survival, DNA damage and repair, cell cycle distribution, cell apoptosis, expression of proteins related to G(2)/M cell cycle checkpoint and apoptosis were measured with colony formation assays, immunohistochemistry, flow cytometry and western blot analysis, respectively. Genistein showed relatively weak toxicity to both cell lines at concentrations in the range of 5-20 mu M. Using the dosage of 10 mu M genistein, the sensitizer enhancement ratios after exposure to X-rays at a 10% cell survival (IC10) were 1.43 for MCF-7 and 1.36 for MDA-MB-231 dcells, respectively. Significantly increased DNA damages, arrested cells at G(2)/M phase, decreased homologous recombination repair protein Rad51 foci formation and enhanced apoptotic rates were observed in both cell lines treated by genistein combined with X-rays compared with the irradiation alone. The combined treatment obviously up-regulated the phosphorylation of ATM, Chk2, Cdc25c and Cdc2, leading to permanent G(2)/M phase arrest, and up-regulated Bax and p73, down-regulated Bcl-2, finally induced mitochondria-mediated apoptosis in both cell lines. These results suggest that genistein induces G(2)/M arrest by the activation of the ATM/Chk2/Cdc25C/Cdc2 checkpoint pathway and ultimately enhances the radiosensitivity of both ER+ and ER- breast cancer cells through a mitochondria-mediated apoptosis pathway
Design study of the SSC-LINAC re-buncher
No full textA re-buncher with spiral arms for a heavy ion linear accelerator named as SSC-LINAC at HIRFL (the heavy ion research facility of Lanzhou) has been constructed. The re-buncher, which is used for beam longitudinal modulation and matching between the RFQ and DTL, is designed to be operated in continuous wave (CW) mode at the Medium-Energy Beam-Transport (MEBT) line to maintain the beam intensity and quality. Because of the longitudinal space limitation, the re-buncher has to be very compact and will be built with four gaps. We determined the key parameters of the re-buncher cavity from the simulations using Microwave Studio software, such as the resonant frequency, the quality factor Q and the shunt impedance. The detailed design of a 53.667 MHz spiral cavity and measurement results of its prototype will be presented
Status of the HIRFL-CSR complex
No full text<span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">The HIRFL-CSR, as an upgrade of the HIRFL, has been put into operation since 2008. Together with a series of improvements of injector cyclotrons, the HIRFL is in a very good state and can provide all ion species from proton to uranium with energy variable from ion source energy to 1 GeV/u (A/q= 2). Present status of the HIRFL-CSR complex is given. Main features realized during the commissioning and operation are described in detail. The progress on physics experiments and cancer therapy are also presented. (C) 2013 Elsevier B.V. All rights reserved.</span
Three dimensional numeric quench simulation of Super-FRS dipole test coil for FAIR project
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Status of Lanzhou Penning Trap for accurate mass measurements
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会议名称</div>
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<span class="FR_label" style="margin: 0px; list-style: none; padding: 0px 4px 0px 0px; font-weight: bold;">会议:</span> <value style="margin: 0px; list-style: none; padding: 0px;">16th International Conference on ElectroMagnetic Isotope Separators and Techniques Related to their Applications (EMIS)</value></p>
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<span class="FR_label" style="margin: 0px; list-style: none; padding: 0px 4px 0px 0px; font-weight: bold;">会议地点:</span> <value style="margin: 0px; list-style: none; padding: 0px;">RIKEN Nishina Ctr Accelerator Based Sci, Matsue, JAPAN</value></p>
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<span class="FR_label" style="margin: 0px; list-style: none; padding: 0px 4px 0px 0px; font-weight: bold;">会议日期:</span> <value style="margin: 0px; list-style: none; padding: 0px;">DEC 02-07, 2012</value></p>
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<span class="FR_label" style="margin: 0px; list-style: none; padding: 0px 4px 0px 0px; font-weight: bold;">会议赞助商:</span>High Energy Accelerator Res Org; Chinese Acad Sci, Inst Modern Phys; Fuji Daimond Int Co Ltd; Hamamatsu Photon K K; IDX Co Ltd; NEC Tokin Corp; REPIC Corp; Shimadzu Corp; Tecno Elect Ind Co Ltd; Thamway Co Ltd</p>he Lanzhou Penning Trap (LPT) is an ion trap facility that aims at accurate mass measurements on fusion-evaporation residues possibly including heavy isotopes and is presently under construction at the Institute of Modern Physics, Chinese Academy of Sciences. The progress and status of the LPT system, including the RFQ cooler and buncher RFQ1L, the Penning trap system, and the 7 T home-made superconducting magnet, are reported. (C) 2013 Elsevier B.V. All rights reserved
Conceptual design of LEST and RFQ for the HIAF linac
No full textIn this paper, we present conceptual design and beam dynamics analysis of the Low Energy Beam Transport (LEBT) and Radio Frequency Quadrupole (RFQ) for the linac section of a heavy ion accelerator facility, high intensity Heavy Ion Accelerator Facility (RAF) project, which is promoted by the Institution of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS). A novel scheme is prompted that a Multi-Ham monic-Buncher (MHB) is used for bunching the continuous beam up-stream of the RFQ. The modulation in and synchronous phase psi of the RFQ do not start from 1.0 and -90 degrees but 1.05 and -45 degrees instead. The results indicate that it is possible to keep transverse emittance growth within tolerable limits while the longitudinal emittiance is much smaller than the design without an external bundler (C) 2013 Elsevier EN. All rights reservedNational Natural Science Foundation of China ;Strategic Priority Research Program of the Chinese Academy of Science
Target Z dependence of Xe L x-ray emission in heavy ion-atom collision near the Bohr velocity: influence of level matching
No full text<span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">X-ray yields for the projectile L-shell have been measured for collisions between Xe20+ and thick solid targets throughout the periodic table with incident energies near the Bohr velocity. The yields show a very pronounced cyclic dependence on the target atomic number. This result indicates that Xe L x-ray emission intensity is greatly enhanced either in near-symmetric collisions or if the binding energy of the Xe M-shell matches the L- or N-shell binding energy of the target.</span
Focusing giga-electronvolt heavy ions to micrometers at the Institute of Modern Physics
No full text<span style="color: rgb(51, 51, 51); font-family: arial, helvetica, sans-serif; font-size: 13px; line-height: 22px; background-color: rgb(248, 248, 248);">To study the radiation effect of cosmic heavy ions of low fluxes in electronics and living samples, a focusing heavy ion microbeam facility, for ions with energies of several MeV/u up to 100 MeV/u, was constructed in the Institute of Modern Physics of the Chinese Academy of Sciences. This facility has a vertical design and an experiment platform for both in-vacuum analysis and in-air irradiation. Recently, microbeam of C-12(6+) with energy of 80.55 MeV/u was successfully achieved at this interdisciplinary microbeam facility with a full beam spot size of 3 mu m x 5 mu m on target in air. Different from ions with energy of several MeV/u, the very high ion energy of hundred MeV/u level induces problems in beam micro-collimation, online beam spot diagnosis, radiation protection, etc. This paper presents the microbeam setup, difficulties in microbeam formation, and the preliminary experiments performed with the facility. (C) 2013 AIP Publishing LLC.</span