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CSRm内靶实验中的轻离子束流寿命模拟研究
No full text建立了内靶对兰州冷却储存环主环束流影响的单粒子跟踪模拟程序,对pellet小丸靶和碳靶对束流带来的负面影响进行了模拟研究,主要讨论CSRm内靶实验中的束流存活率和束流寿命状态。结果显示利用厚度为1×1016atoms.cm-2小丸内靶时,2.6 GeV质子束流寿命在100 s量级,而对于目前技术水平下的碳膜靶(厚度为5×1017atoms.cm-2),质子束流寿命为s量级;束流寿命和束流能量基本成正比关系,束流寿命和内靶厚度近似成反比关系
~(12)C~(6+)重离子辐照胡麻种子初步研究
No full text本文研究了6×108cm-2、1.8×109cm-2和3.6×109cm-2的12C6+重离子束辐照对胡麻种子M1代生物学性状和DNA分子多态性等方面的影响。6×108cm-2辐照处理可引起胡麻发芽率提高,促进植株株高,增强花粉活力。同时辐照处理使胡麻种子千粒重和含油量有不同程度提高,辐射剂量越高,两者数值越大,3.6×109cm-2辐射剂量的胡麻种子千粒重和含油量与对照组的相比分别高出了16.5%和19.9%,此外在此剂量处发现了花粉发生了形态变化。辐照处理对胡麻DNA分子也产生了影响,筛选出的14个随机引物可以扩增出清晰、稳定、重复性好的DNA片段,有52个是多态性DNA片段,比率为52.5%
核子-核子碰撞截面对同位素标度参数α的介质效应
No full text核子能量在40—60MeV能区范围,对在两对重离子中心碰撞系统40Ca+48Ca和60Ca+48Ca以及112Sn+112Sn和124Sn+124Sn的反应中就同位素标度参数α对于核子-核子碰撞截面σmNeNd(αm)的介质效应进行了研究.结果发现,核子-核子碰撞介质效应对同位素标度参数α具有明显的影响.就产生这种介质效应的机理进行了分析和讨论
Design and simulation of charge sensitive preamplifier with CMOS FET implemented as feedback capacitor C-fp
No full textIn this paper, to design a new preamplifier for optimum performances with charged-particle or heavy-ion detectors, the CMOS FET is implemented as a feedback capacitor C-fp, so that the entire system should be built only with MOSFET. This work is a revolution design because to realize an ASIC for a preamplifier circuit, the capacitor will also be included. We succeed after a simulation to maintain a rise time less than 3 ns, the output resistance less than 94 Omega and the linearity almost good.Third World Academy of Sciences
Institute of Modem Physics
Chinese Academy of Sciences
NSFC 1067515
NADPH oxidase-mediated generation of reactive oxygen species: A new mechanism for X-ray-induced HeLa cell death
No full textOxidative damage is an important mechanism in X-ray-induced cell death. Radiolysis of water molecules is a source of reactive oxygen species (ROS) that contribute to X-ray-induced cell death. In this study, we showed by ROS detection and a cell survival assay that NADPH oxidase has a very important role in X-ray-induced cell death. Under X-ray irradiation, the upregulation of the expression of NADPH oxidase membrane Subunit gp91(phox) was dose-dependent. Meanwhile, the cytoplasmic subunit p47(phox) was translocated to the cell membrane and localized with p22(phox) and gp91(phox) to form reactive NADPH oxidase. Our data Suggest, for the first time, that NADPH oxidase-mediated generation of ROS is an important contributor to X-ray-induced cell death. This suggests a new target for combined gene transfer and radiotherapy.National Natural Science Foundation of China 10675151
30870586
Postdoctoral Foundation of China 20070410232
Lanzhou Prajna Union Biology Technique Co., Lt
V5+-doped Bi3.4Yb0.6Ti3O12 fatigue resistant ferroelectric thin films
No full textIn this paper, a serial of Bi3.4Yb0.6Ti3-xVxO12 (BYTV) thin film with different V5+ contents were deposited on Pt/Ti/SiO2/Si substrates by chemical solution deposition (CSD). The crystallized phase and electrical properties of the films were investigated using X-ray diffraction, polarization hysteresis loops, leakage current-voltage, and fatigue test. From our experimental results, it can be found that the ferroelectric properties can be improved greatly using V5+-doped in Bi3.4Yb0.6Ti3O12 (BYT) thin film, compared with the reported BYT thin film. The remanent polarization was enhanced and excellent leakage current characteristic with 10(-11)A at the bias voltage of 4V, which is much lower than the BYT thin film or some reported bismuth layer-structure ferroelectric films. Fatigue test shows that the fabricated films have good anti-fatigue characteristic after 10(10) switching cycles. (c) 2008 Published by Elsevier B.V
Cross sections for transfer ionization in ion-helium collisions
No full textA simple model has been developed within the independent-particle model (IPM) based on the Bohr-Lindhard model and classical statistical model. Cross sections for transfer ionization of helium by ions A(q+) (q = 1-3) are calculated for impact energies between 10 and 6000 keV/u. The calculated cross sections are in good agreement with the experimental data of helium by He(1-2)+ and Li(1-3)+
Beam dynamics design of an RFQ for a planned accelerator, which uses a direct plasma injection scheme
No full textTo meet the requirements of providing high-intensity heavy ion beams the direct plasma injection scheme (DPIS) was proposed by a RIKEN-CNS-TIT collaboration. In this scheme a radio frequency quadrupole (RFQ) was joined directly with the laser ion source (LIS) without a low-energy beam transport (LEBT) line. To find the best design of the RFQ that will have short length, high transmission efficiency and small emittance growth, beam dynamics designs with equipartitioning design strategy and with matched-only design strategy have been performed, and a comparison of their results has also been done. Impacts of the input beam parameters on transmission efficiency are presented, too. (C) 2008 Elsevier B.V. All rights reserved
Symmetry energy and isovector giant dipole resonance in finite nuclei
No full textWe study the relationship between the properties of the isovector giant dipole resonance of finite nuclei and the symmetry energy in the framework of the relativistic mean field theory with six different parameter sets of nonlinear effective Lagrangian. A strong linear correlation of excited energies of the dipole resonance in finite nuclei and symmetry energy at and below the saturation density is found. This linear correlation leads to the symmetry energy at the saturation density at the interval 33.0MeV <= S(po) <= 37.0 MeV. The comparison to the present experimental data in the soft dipole mode of (132) Sn constrains approximately the symmetry energy at p = 0.1 fm(-3) at the interval 21.2MeV similar to 22.5 MeV. It is proposed that a precise measurement of the soft dipole mode in neutron rich nuclei could set up an important constraint on the equation of state for asymmetric nuclear matter
Survivin expressions in human hepatoma HepG2 cells exposed to ionizing radiation of different LET
No full textSurvivin is a member of the inhibitors of apoptosis (IAP) protein family that interferes with post-mitochondrial events including activation of caspases. To examine the regulation of survivin expression in response to irradiation with different linear energy transfer (LET), human hepatoma HepG2 cells were irradiated in vitro with X-rays and carbon ions. Cellular sensitivities to low- and high-LET radiation were determined by colony formation. Survivin expression at mRNA and protein level were measured with RT-PCR and Western blot analyses, respectively. Radiation-induced cell cycle arrest and apoptosis were investigated with flow cytometry. We found that low-LET X-rays induced dose-dependent increases in survivin expression. After exposure to high-LET carbon ions, survivin expression gradually increased from 0 to 4 Gy, and then declined at 6 Gy. More pronounced survivin expression, stronger G(2)/M phase arrest was observed after exposure to carbon ions in comparison with X-rays at doses from 0 to 4 Gy. These observations indicate that there is a differential survivin expression in response to different LET radiations and the cycle arrest mechanism may be associated with it. In addition, our data on induction of apoptosis are compatible with the assumption that survivin expression induced by low-LET X-rays radiation may play a critical role in inhibiting apoptosis. However, after irradiation with ions, an anti-apoptotic function of survivin is not evident, possibly because of the serious damage produced by densely ionizing radiation