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Two Cases of Pasteurella Multocida Infection of the Lung that Required Differentiation from Mycobacterial Infections
Full text linkCase 1 : A 62-year-old woman underwent pre- and post-operative chemotherapy and mastectomy for right breast cancer. After treatment, she experienced a chronic cough. Chest computed tomography (CT) showed exacerbation of bronchiectasis and centrilobular nodules in the right middle lobe and a new appearance of centrilobular nodules in the right lower lobe. As pulmonary tuberculosis was suspected, bronchoscopy was performed and Pasteurella multocida was isolated. Long-term erythromycin therapy proved effective and was maintained,whereas adding a 14-day amoxicillin course to ongoing erythromycin yielded minimal clinical impact.Case 2 : A 66-year-old man underwent Chest CT for follow-up of rheumatoid arthritis and chronic bronchitis,which showed an enlarged cavity in the right upper lobe. Pulmonary mycobacteriosis was suspected. Bronchoscopy was performed and P. multocida was isolated. Finally, amoxicillin treatment was effective.P. multocida infection is a well-known skin and soft tissue infection triggered by trauma caused by pet animals,such as dogs and cats ; however, it is also known to cause respiratory infections. P. multocida pulmonary infections present with centrilobular nodules accompanied by bronchiectasis on imaging in some cases, and may require differentiation from pulmonary mycobacteriosis, such as M. tuberculosis and non-tuberculous mycobacterial infections, although this is not well known. In recent years, the incidence of P. multocida has increased,and differentiating between pulmonary mycobacteriosis and P. multocida pulmonary infections is important.Herein, we report two cases of pulmonary infection with P. multocida that required differentiation from pulmonary mycobacteriosis. Shinshu Med J 73 : 241―244, 2025journal articl
Hypertensive disorders of pregnancy increase the incidence of febrile seizures in offspring（妊娠高血圧症候群と子の熱性けいれんとの関連）
Full text link信州大学Shinshu University博士（医学）次の雑誌に発表。 /Reproduced with permission from Springer Nature. Pediatric Research 96(1) :223-229(2024); doi:10.1038/s41390-024-03057-y © The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc 2024.doctoral thesi
Pulmonary metastases from malignant melanoma showing ground-glass opacity nodules（すりガラス濃度結節を呈する悪性黒色腫の肺転移に関する検討）
Full text link信州大学Shinshu University博士（医学）次の雑誌に発表。 /Japanese Journal of Radiology 43(6) :949-957(2025); doi:10.1007/s11604-025-01745-1 © The Author(s) 2025. This article is licensed under a Creative Commons Attribution 4.0 International License.doctoral thesi
Early Prediction of Acute Kidney Injury after Pediatric Cardiac Surgery
No full textBackground : Cardiac surgery-associated acute kidney injury (CS-AKI) following pediatric cardiac surgery is associated with increased postoperative mortality and prolonged pediatric intensive care unit (PICU) stay. Early diagnosis and intervention are therefore essential. We retrospectively evaluated whether CS-AKI could be predicted using perioperative blood parameters, cardiopulmonary bypass (CPB) data, and postoperative furosemide responsiveness. Methods : This retrospective study included 238 patients admitted to the PICU of Nagano Children’s Hospital between April 2020 and March 2024. Age, body surface area (BSA), preoperative and postoperative serum creatinine (sCr), blood urea nitrogen (BUN), sodium, potassium, chloride, albumin, postoperative bicarbonate, lactate, serum osmolality, CPB time, and postoperative furosemide responsiveness were compared between AKI and non-AKI groups. Variables showing significant differences were analyzed to identify predictors of AKI onset. Results : Significant differences between the AKI and non-AKI groups were observed in age, BSA, ΔCr (postoperative sCr-preoperative sCr), ΔK, CPB time, time to furosemide administration, and urine volume in response to furosemide. Logistic regression analysis identified CPB time, ΔCr, and furosemide-induced urine output as the most relevant predictors. In contrast, furosemide administration timing, BSA, ΔK, and age were less predictive. Highly relevant data were assigned a score of 2, and others a score of 1. A total score ≥ 6 predicted AKI onset with 90.8 ％ sensitivity and 90.5 ％ specificity. Conclusion : Perioperative clinical and laboratory parameters can predict CS-AKI within 24 hours after pediatric cardiac surgery. Integrating these findings with established AKI biomarkers may further enhance prediction accuracy. Shinshu Med J 73 : 399― 406, 2025journal articl
接合伝達性プラスミドRP4及びSAP1の伝達機構解明【本文の要旨】
No full text信州大学Shinshu University博士（医工学）この博士論文は、次の学術雑誌論文を一部に使用しています。 || Bioscience, Biotechnology, and Biochemistry 89(1) :133-140(2024); doi:10.1093/bbb/zbae159 © The Author(s) 2024. Published by Oxford University Press on behalf of Japan Society for Bioscience, Biotechnology, and Agrochemistry.|| Bioscience, Biotechnology, and Biochemistry 89(9) :1349-1356(2025); doi:10.1093/bbb/zbaf090 © The Author(s) 2025. Published by Oxford University Press on behalf of Japan Society for Bioscience, Biotechnology, and Agrochemistry. All rights reserveddoctoral thesi
Study on hydrovoltaic effect-based devices for energy harvesting and storage from microdroplet capture(微小液滴捕獲によるエネルギー収集・貯蔵のためのハイドロボルタイック効果に基づくデバイスに関する研究)
No full text信州大学Shinshu University博士（工学）この博士論文は、次の学術雑誌論文を一部に使用しています。 || Advanced Materials Technologies 8(19) :2300638(2023); doi:10.1002/admt.202300638 © 2023 The Authors. Advanced Materials Technologies published byWiley-VCH GmbH. This is an open access article under the terms of theCreative Commons Attribution License|| Chemical Engineering Journal 480 :148125(2024); doi:10.1016/j.cej.2023.148125 © 2023 Elsevier B.V. All rights reserved.|| Chemical Engineering Journal 496 :154164(2024); doi:10.1016/j.cej.2024.154164 © 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.doctoral thesi
2輪自動車のモデルベース開発に向けた実時間走行シミュレーションモデルの研究
No full text信州大学Shinshu University博士（工学）この博士論文は、次の学術雑誌論文を一部に使用しています。 || 日本機械学会論文集 90(932) :23-00226(2024); doi:10.1299/transjsme.23-00226 © 2024 The Japan Society of Mechanical Enginee 学会より許諾済み この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。|| Mechanical Engineering Journal 11(6) :24-00297(2024); doi:10.1299/mej.24-00297 © 2024 The Japan Society of Mechanical Engineers 学会より許諾済み This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.|| Mechanical Engineering Journal 12(5) :24-00135(2025); doi:10.1299/mej.25-00135 © 2025 The Japan Society of Mechanical Engineers 学会より許諾済み This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.doctoral thesi
