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機械学習を用いた表情解析と医療予測モデルに関する研究
Get PDF信州大学Shinshu University博士（医工学）この博士論文は、次の学術雑誌論文を一部に使用しています。 || ライフサポート 34(3) :83-89(2022); doi:10.5136/lifesupport.34.83 ; 著作物の著作権はライフサポート学会に帰属します。|| Sensors and Materials 37(2) :671-682(2025); doi:10.18494/SAM5184 © MYU K.K. This work is licensed under a Creative Commons Attribution 4.0 International License.doctoral thesi
疎水性ナノスケール細孔中の水分子集団への局所摂動の効果
Get PDF信州大学Shinshu University博士（理学）この博士論文は、次の学術雑誌論文を一部に使用しています。 || Reprinted with permission from J. Phys. Chem. C 2024, 128, 30, 12632–12641. Copyright 2024 American Chemical Society.|| Adsorption 31 :19(2025); doi:10.1007/s10450-024-00576-2 © The Author(s) 2024. This article is licensed under a Creative Commons Attribution 4.0 International License.doctoral thesi
Relationship between Bone Marrow Megakaryocyte Morphology and the Pathophysiology of ITP
Get PDFImmune thrombocytopenia (ITP) is a hemorrhagic disease primarily caused by platelet destruction and reduced platelet production from megakaryocytes due to autoantibodies targeting platelet glycoproteins and other antigens, resulting in thrombocytopenia. While the evaluation of bone marrow megakaryocytes is important for distinguishing different causes of thrombocytopenia, recent ITP treatment guidelines state that bone marrow examination itself is not particularly useful for diagnosing ITP. However, there are only a limited number of studies focusing on ITP, particularly on megakaryocyte morphology, indicating that further research is needed. In this study, we compared the morphology of bone marrow megakaryocytes and their platelet production patterns between ITP and control groups. Bone marrow smear specimens were analyzed to measure megakaryocyte major axis length, area, and nuclear area, as well as the number and rate of platelet attachments on megakaryocyte surfaces. The ITP group exhibited greater megakaryocyte major axis length and a larger megakaryocyte area compared to the control group. Furthermore, the number of platelet attachments on megakaryocyte surfaces was significantly lower in ITP patients. Additionally, megakaryocytes in the pregnancy-complicated group had larger major axis length and areas than those in the non-complicated group. In refractory cases requiring thrombopoietin receptor agonists (TPORAs) for treatment, the cell major axis length, cell area, and nuclear area were all larger. The percentage and number of platelet attachments on megakaryocyte surfaces were also lower in patients with Helicobacter pyloripositive (H. pylori-positive) ITP. The morphology of megakaryocytes in ITP exhibits characteristics related to its pathology. Therefore, focusing on the size of megakaryocytes and the appearance of platelet attachments on megakaryocyte surfaces in bone marrow smears may be useful for differentiating ITP.journal articl
Teacher Awareness and the Challenges of Implementing Financial Consumer Education: Results and Analysis of a Survey of Teachers on Financial Consumer Education
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Impact of tailored message notifications for frailty prevention in older adults : a quasi-randomized controlled study using a regression discontinuity design （高齢者におけるフレイル予防のためのテーラーメードメッセージ通知の影響：回帰不連続デザインを用いた準ランダム化比較試験）
Get PDF信州大学Shinshu University博士（保健学）次の雑誌に発表。 /Journal of Physical Therapy Science 36(10) :647-655(2024); doi:10.1589/jpts.36.647 © 2024 by the Society of Physical Therapy Science. Published by IPEC Inc. This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.doctoral thesi
LGR5 expression and clinicopathological features of the invasive front in the fat infiltration area of pancreatic cancer（膵臓癌の脂肪組織への浸潤部におけるLGR5の臨床病理学的特徴）
Get PDF信州大学Shinshu University博士（医学）次の雑誌に発表。 /Diagnostic Pathology 17(1) :21(2022); doi:10.1186/s13000-022-01203-w © The Author(s). 2022. This article is licensed under a Creative Commons Attribution 4.0 International License.doctoral thesi
Associations Between Morphological Phenotypes of COPD and Clinical Characteristics in Surgically Resected Patients with COPD and Concomitant Lung Cancer（COPD合併肺癌の外科的切除患者におけるCOPD形態学的フェノタイプと臨床的特徴の関連）
Get PDF信州大学Shinshu University博士（医学）次の雑誌に発表。 /International Journal of Chronic Obstructive Pulmonary Disease 17 :1443-1452(2022); doi:10.2147/COPD.S366265 © 2022 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, 3.0) License.doctoral thesi
Associations between prenatal exposure to per- and polyfluoroalkyl substances and wheezing and asthma symptoms in 4-year-old children: The Japan Environment and Children’s Study（妊婦の有機フッ素化合物（PFAS）ばく露と生まれた子どもの4歳時におけるぜん鳴・ぜん息症状の有無との関連：子どもの健康と環境に関する全国調査）
Get PDF信州大学Shinshu University博士（医学）次の雑誌に発表。 /Environmental Research 240(1) :117499(2024); doi:10.1016/j.envres.2023.117499 © 2023 Elsevier Inc. All rights reserved.doctoral thesi