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Application of TiO2 in Photocatalytic Bacterial Inactivation: Review
No full textPhotocatalytic pathogen inactivation is gaining increasing importance due to the rising number of microbial species resistant to conventional antibacterial agents. Titanium dioxide (TiO2)-based photocatalysts have emerged as a promising solution, being not only potent antibacterial agents but also environmentally friendly and capable of simultaneously degrading organic pollutants. This review summarizes recent advances in the antibacterial performance of different TiO2 modifications, including commercial nanopowders, nanoparticles with various morphologies, thin films, composites, and polymer-supported nanostructures, all primarily activated under UV light. Given the limited ability of pristine TiO2 to harvest solar radiation, we also highlight the most recent strategies for designing visible-light-responsive TiO2, such as doping, incorporation of plasmonic metal nanoparticles, formation of heterostructures, and interfacial charge transfer complexes. In addition, we discuss the fundamental structural features of TiO2, the mechanisms of reactive oxygen species (ROS) generation involved in bacterial inactivation, and kinetic models describing antibacterial efficiency. These insights aim to advance the understanding and development of eco-friendly, cost-effective, and sustainable photocatalytic disinfection technologies
Experimental research of the lignite drying process in packed bed
No full textOne of the biggest challenges is the development of low-carbon technologies for coal utilization. Clean coal technologies are a group of measures aimed at reducing carbon dioxide emissions by increasing the energy efficiency of coal-fired power plants. Experimental studies were carried out on the convective drying of lignite. The drying process was investigated under the packed bed conditions. The effects of sample size, temperature and coal grain size on the drying rate were investigated. Temperature was recognized as the most influential parameterIOC2025 : 56th International October Conference on Mining and Metallurgy; October 22-25, 2025, Bor Lake, Serbia
Reactive oxygen species (ROS) and late-stage cancer (Cancer metastasis)
No full textReactive oxygen species (ROS) play a crucial role in cancer development, from the earliest to the latest stages, including the formation of metastases at distant sites. Elevated ROS levels have been shown to facilitate metastasis by modulating various cellular signaling pathways involved in cell proliferation, invasion, migration, angiogenesis, cell survival, and resistance to therapy. However, only those cells that have adapted to oxidative stress and excessive ROS production can successfully undergo the process of metastasis. Therefore, understanding the role of oxidative stress in the progression of cancer and targeting this process through therapeutic approaches are of great importance in combating various types of cancer. Here, we provide an overview of the latest findings on the molecular mechanisms of ROS interplay in metastasis formation with a particular reference to their role in liver, colorectal, and breast cancer
Solvothermal synthesis of hematite (α-Fe2O3) nanoparticles: Influence of surfactants on morphology, magnetic anisotropy, MRI relaxivity and biocompatibility
No full textRecent advancements in synthesis of hematite (α-Fe2O3) nanocrystals have enabled precise control of particle size and shape, thereby enhancing their use in catalysis, photonics, magnetic devices, electronics, medical diagnostics, magneto-mechanical actuators, solar cells and sensors. This study emphasizes the role of surfactants in the solvothermal synthesis of α-Fe2O3 nanoparticles, uncovering a novel connection between particle morphology and functional properties. By precisely adjusting surfactant concentrations (sodium hydroxide and acetic acid), the hematite particle morphology transitions from irregular shapes to uniform, plate-like structures. This transformation significantly enhances magnetic anisotropy, resulting in high coercivity (HC = 1725 Oe, above the Morin transition TM = 263 K) in the plate-like hematite nanoparticles, whereas irregularly shaped hematite nanoparticles exhibit coercivities of 235 Oe and 256 Oe (above the Morin transition TM = 251 and TM = 239 K, respectively). Furthermore, the study establishes a clear relationship between hematite nanoparticle shape and MRI relaxivity. The MRI results indicated that hematite nanoplates had superior transverse relaxivity rates (r2 = 8.68 mM−1 s−1) compared to the irregular hematite nanoparticles (r2 = 5.28 mM−1 s−1). Conversely, the irregular hematite nanoparticles displayed better longitudinal relaxivity (r1 = 0.304 mM−1 s−1) than the hematite nanoplates (r1 = 0.041 mM−1 s−1). Furthermore, the hematite nanoparticles demonstrated low cytotoxicity, indicating they are safe for cells. These findings suggest that controlling iron oxide nanoparticle morphology is crucial for enhancing their applications in magnetic materials and in biomedicine. © 2025 Elsevier B.V.Peer-reviewed version available at: [https://vinar.vin.bg.ac.rs/handle/123456789/14797
Chronic Oral D-Galactose Induces Oxidative Stress but Not Overt Organ Dysfunction in Male Wistar Rats
No full textD-galactose (d-gal) plays numerous roles in the organism as an energy-providing nutrient and also an important constituent of the complex glycoconjugates. However, excessive amounts of d-gal activate alternative metabolic pathways that can lead to the development of a pro-oxidative environment. This feature is used in numerous aging studies which implied intraperitoneal (i.p.) or subcutaneous (s.c.) administration of d-gal for a prolonged time. The present study aims to investigate the systemic effects of orally administered d-gal (200 mg/kg and 500 mg/kg, dissolved in tap water, for 6 weeks) by analyzing oxidative stress parameters in the liver, kidney, and heart. For comparison with natural aging, the effects were studied in rats aged 12, 18, 24, and 30 months. In addition, histopathologic analyzes and serum biochemical measurements were performed to investigate the potential structural and functional organ damage induced by d-gal administration. Our findings show that chronic oral administration of d-gal induces oxidative stress in rat organs and mimics some aspects of natural aging similar to those of 30-month-old rats. Consistent with its primary role in galactose metabolism, the liver exhibited the most pronounced oxidative damage. However, despite the increased oxidative stress, only minor histopathological changes were observed, while organ function remained largely unaffected. Oral intake of d-gal was found to have milder effects compared to i.p. or s.c. injections, suggesting that this model may induce some features of natural aging but without overt organ dysfunction
Nanocomposite enhanced molecularly imprinted polymer for electrochemical detection of naringenin in plant-based samples
No full textA novel molecularly imprinted polymer (MIP)-based electrochemical sensor has been developed for the selective detection of naringenin (NAR) in various real-world samples, including plant extracts, wine, and herbal supplements. To enhance the active surface area and porosity of the glassy carbon electrode (GCE), a 2D/0D nanocomposite composed of graphene oxide (GO) and cobalt ferrite (CFO) nanoparticles, CFO_GO, was incorporated into the sensor design. 4-aminobenzoic acid (4-ABA) was selected as the functional monomer to prepare the MIPs. The polymerization process was performed using ethylene glycol dimethacrylate (EGDMA) as the crosslinking agent, 2-hydroxyethyl methacrylate (HEMA) as the basic monomer, and 2-methylpropiophenone as the initiator. The developed MIP-based sensor was designed for the electrochemical detection of NAR in real samples such as Solanum lycopersicum L. (tomato) fruit, Citrus × limon (L.) Osbeck (lemon), oak (Quercus) bark, red wine, and herbal supplements demonstrate their potential for practical applications in analyzing food and herbal products. Morphological and electrochemical characterizations of the designed NAR/CFO_GO/4-ABA@MIP-GCE sensor were performed using scanning electron microscopy (SEM), cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). The linear range for the determination of NAR using the indirect method (5.0 mM [Fe(CN)6]-3/-4) was found to be 1.0 × 10-13 M-1.0 × 10-12 M, and the limit of detection (LOD) and limit of quantification (LOQ) for standard solutions were 2.84 × 10-14 and 9.47 × 10-14 M, respectively. As a result of the study, the developed MIP-based electrochemical sensor was suitable for detecting NAR with high specificity, selectivity, and sensitivity. Additionally, recovery studies were performed to determine the practical applicability of the sensor, and the results were satisfactory. The developed sensor platform can be considered a reliable and sensitive analytical tool for determining NAR
Crystal structure of bis(μ2-1,5-bis[(E)-1-(2-hydroxyphenyl)ethylidene] thiocarbonohydrazide)-bis(dimethylformamide)-dizinc(II) dimethylformamide solvate, C40H46N10O6S2Zn2×C3H7NO
No full textC40H46N10O6S2Zn2⋅C3H7NO, orthorhombic, Pbca (no. 61), a = 15.2562(4) Å, b = 20.5310(6) Å, c = 29.7848(6) Å, V = 9329.3(4) Å3, Z = 8, R gt (F) = 0.0576, wR ref (F2) = 0.0870, T = 180 K
Advances in solid-state kinetics models: Case studies of pyrophyllite dehydroxylation and doped MgH2 dehydration
No full textPyrophyllite (Al2[Si4O10](OH)2) is material widely used in ceramics production, while MgH2 is often part of glass-ceramic electrolyte composites. The aim of this study is to investigated kinetics of pyrophyllite dehydroxylation and MgH2 dehydration, which are process important for above- mentioned applications. Pyrophyllite ore was mixed with 2 10 wt.% of AgNO3 and subjected to mechanochemical activation for varying milling durations. MgH2 was synthesized with the addition of 2 5 wt.% of W and Mo, also at different time intervals. All materials were characterized using X-ray diffraction, FTIR spectroscopy, dynamic light scattering, and scanning electron microscopy. For the pyrophyllite/AgNO3 composite, thermogravimetric analysis was performed, while for the doped MgH2, temperature-programmed desorption curves were used to investigate the reaction kinetics. Kinetic curves were modeled using several approaches. The classical kinetic model failed to describe either process accurately, suggesting that both exhibit dispersed kinetics. Mass loss during non-isothermal heating of pyrophyllite was described using a linear combination of two Weibull functions. In contrast, the dehydration of doped MgH2 required Brouers Sotolongo functions, which are more general representations of fractal kinetics. The kinetic parameters calculated from the modeled curves were correlated with the structural and morphological features of the materials.Advanced Ceramics and Application : 13th Serbian Ceramic Society Conference : Program and the Book of Abstracts; September 8-10, 2025; Belgrade
Superparamagnetic iron oxide nanoparticle clusters with porous silica shell as a highly biocompatible theranostic platform
No full textAdvanced Ceramics and Application : 13th Serbian Ceramic Society Conference : Program and the Book of Abstracts; September 8-10, 2025; Belgrade
Colossal permittivity of sintered BaFe12O19 doped with SiO2 in the very low frequency region
No full textAdvanced Ceramics and Application : 13th Serbian Ceramic Society Conference : Program and the Book of Abstracts; September 8-10, 2025; Belgrade