Res Medica (E-Journal)
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    Editorial

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    Ask an etymologist or even a schoolboy with the Latin still tingling in his ears about the word hospital. You might glean more meanings subsumed under the word than bargained for; but care for the homeless is one interpretation that has fallen by the wayside. This is as well when the scene of the overcrowded, understaffedHealth Service is surveyed. Yet how much in fact is the care for the homeless (a matter of community health) the province of the medical profession

    Mutation Research and Human Welfare

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    From an address to the Society in November  1968.GENETICAL RADIATION DAMAGEKnowledge gained from mutation research can be put to various uses for the benefit of mankind. One of them is assessment of genetical hazards from ionizing radiations. Before the war, this meant almost exclusively X-rays used in diagnosis and therapy.  H. J. Muller, who in 1927 discovered the mutagenic action of X-rays, almost at once entered upon a campaign against the reckless use of radiation in medical practice. Especially in the USA , it was fashionable for the G.P. to have in his surgery a fluoroscope with, usually, an unknown and, often, a very high output of radiation and to use it indiscriminately even where less dangerous methods of diagnosis were available. There was also a practice of temporarily sterilizing men by radiation; when these men later on became fertile again they produced children from sperm that had been heavily irradiated as spermatogonia. In women, similarly high X-ray doses were used to produce fertility by follicle rupture. Until the war, the medical profession took very little notice of Muller. This careless attitude changed when fall-out and nuclear accidents became a major concern. Nowadays many national and international organisations, in all of which geneticists play an important role, are engaged in monitoring the amount of radiation to which we are exposed, in assessing its genetical consequences and in fixing “permissible” levels of radiation

    Assessment of the Psychological State

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    THE MENTAL STATENumerous of the clinical signs characterizing the mental state of the patient will have become apparent during history taking. The clinician then has the opportunity to study any aspect of the psychological state which calls for special further evaluation.1. General appearance and behaviour: The patient is described tersely but vividly, to provide a record which will suffice to call him to mind as he looked when in the examination room : his posture, his expression, his clothes, his mannerisms, his reactions to the clinician, and his mode of presenting himself. In the case of a mute or stuperose patient this aspect of the mental state may be among the most revealing.2. Thought processes: Talk is externalized thought, thus the clinician notes how ideas are handled and the manner in which the patient arranges and expresses his concepts. The major pathology may be in this psychological sector, and be disclosed in disordered syntax : as when a schizophrenic patient juxtaposes apparently unrelated references to a portion of his body and the river he lived close to as a child : “This is my arm and the Couch is in Essex”

    Posterity’s Inheritance Mechanised?

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    Research ProjectPractically anything written in medical journals at present concerning computers may quite safely be considered ‘topical’ or ‘exciting’ or ‘relevant to the future’. The term ‘computer revolution’ is bandied about and we are told time and again that every practising doctor will have to acquire considerable knowledge of computers in order to make full use of their services.1But in every ointment there is a fly. We must not get carried away in our enthusiasm to throw all our information at some unsuspecting programmer and say, “feed it in”.  The fear of being “dazzled by optimistic claims" has been lately expressed2 but it is doubtful that much attention will be payed to it in this, the Poseidon nickel rash of medicine in the seventies.There is great need for all medical people to fully realize the potential of this not too awesome omnivorous machine and to budget carefully and after considerable thought.3 Medical records is a bit of a latecomer to this field, and only recently has money been placed at the disposal of experts to work this one out.  It is often thought that medical records breed.  They are certainly multiplying at a great rate and their retention and storage for indefinite periods of time pose great problems.

    The R.M.S. Abroad

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    When Ted Duvall asked me to write a description of the Leiden trip, I went away and scribbled down the events as they occurred, in chronological order, right down to the last cup of coffee, the last Bokma. I did this because I was afraid that the events, put out of focus, even at the time, by the action of various euphoric agents, would in due course shift themselves beyond recall. Dutch Geneva, and another beverage which went down well with us — Trapiste Triple (Trapiste because made by Trappist monks, triple because about three times stronger than normal beer) — these were not solely responsible for the dreamlike quality of our eight days in Holland. In fact, by our last day, we were all helpless with fatigue. It had all started on the night train from Edinburgh to King\u27s Cross — not a sleeper, of course; that would have been contrary to the essential character of the trip. Most of us didn\u27t sleep at all. We played Bridge till four and then stared disconsolately out into the grey murk, jealous of the slumbering Ailsa and her valium. (Although, to be fair, she did offer us all a fix.) It was even worse in London because we had to spend three hours of the early morning hanging around in Liverpool St. Station, shivering and looking more and more haggard. Finally, some of the party chose to live apart for the duration of the voyage from Harwich to the Hook of Holland. It was becoming clear that there were to be only two big disgraces on this trip — sleeping, and vomiting. (The rest of us relaxed on deck or in the bar, charmed, along with our cosmopolitan fellow passengers, by the colourful and extrovert behaviour of some of our fellow countrymen — who seem to turn up wherever you go — entertaining us with their stirring songs and quaint partisan chants

    Syllabus for the 242nd Session (1978-79)

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    Wednesday        Dissertation25th April           Mr. Alan Boyd, B.Sc.Wednesday        Annual Extraordinary General Meeting2nd MayFriday                President\u27s Valedictory Address11th May           Dr. Edward Duval

    Book Reviews

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    PRACTICAL STUDENT OBSTETRICS Bende, S & Tindall, VR Heinemann, 1980 pp; 435. £12.50ESSENTIALS OF DERMATOLOGY J.L. Burton, Churchill Livingstone. 1980. pp. 196. £3.95ESSENTIAL PAEDIATRICS Hull, D. & Johnston, D.l. Churchill Livingstone, 1981 pp.305. £10.00PRACTICAL PROCEDURES IN CLINIC AL MEDICINE Michael J. Ford and John F. Munro Churchill Livingstone 1980 pp. 128. £4.25LECTUR E NOTES ON CLINICAL ONCOLOGY: Hancock, B.W. & Bradshaw, J.D.Blackwell, 1981.pp. 176. £5.50INTRODUCING ANATOMY J.D. Lever London: William Heinemann Medical Books Ltd. 1980.pp. 288. £7.95

    Panel Discussion

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    The Management of the Patient with Angina PectorisChairman: I thought that we might concentrate this discussion on the more controversial aspects of treating angina but I realise that almost the only uncontroversial aspect is the use of short term nitrites. It is a tribute to Lauder Brunton that this seems to be the only form of treatment on which we would probably all agree. Much more controversial is the use of long-action nitrites. Should one employ these clinically?Dr. Friesinge

    The Investigation of a Patient Believed to Have a Blood Disorder

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    Much has been said in the first part of this article about the important points to note in taking the history, and various possible physical signs have been considered.  In many instances, however, further investigations are necessary before a diagnosis can be made or confirmed. These cannot be considered in great detail in an article of this nature, since complete consideration would involve writing a full textbook of haematology, but some of the more important investigations can be outlined under three headings according to the degree of complexity or specialisation

    Study of the Inhibitory Action of Marboran on the Replication Cycle of Cowpox Virus

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    Research ProjectThe project undertaken involved a study of the effects of the inhibitor N-methyl isatin thiosemicarbazone (Marboran) on the replication cycle of cowpox virus in monolayers of baby hamster kidney cells (BHK).The cytotoxic effects of Marboran on the BHK cells were studied and were found to be directly related to the time of exposure to the inhibitor with a maximum tolerated dose of Marboran of 30/UM/ml. after 7 days. This drug concentration was subsequently used to avoid the occurrence of a cytotoxic effect of Marboran masking any cytopathic effect (CPE) of the virus when both inhibitor and virus were used in conjunction

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