Journal for ReAttach Therapy and Developmental Diversities (JRTDD)
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Level of Credit Risk in the Quality of Financial Management
Risk is an uncertain situation in any activity carried out and any natural or legal person is exposed to this phenomenon. In the financial field, it is vitally important to predict the future to make the best possible decision. The study aimed to determine the credit risk in the quality of financial management of Investment Fund Management Companies in Peru. 2019 – 2022. Likewise, the methodology used was based especially on a descriptive model, using a qualitative approach. Data collection was carried out through the survey and a questionnaire, prepared with questions about the variables under study (Level of credit risk and quality of financial management), where a survey was applied aimed at professional operations managers, risk managers and general managers of Investment Fund Management Companies, which with their contributions provided us to clarify our questions. The results found that the level of credit risk and payment capacity significantly affected the quality of financial management of Investment Fund Management Companies in Peru, having an impact on the delinquency of investment fund management companies, because if clients do not generate the adequate level of cash it can affect their level of liquidity. Concluding that in order to properly manage a loan portfolio and make an adequate allocation of resources, Financial Intermediation Entities are in need of measuring credit risk
Podcast as a Therapy on Motivation, Subjective Happiness and Quality of Life among Young Adults
The contemporary landscape of media consumption has seen a remarkable surge in the popularity of podcasts. These audio-based platforms have emerged as dynamic vehicles for the dissemination of informative and engaging content across diverse audiences. This research undertakes a comprehensive exploration into the potential ramifications of motivation derived from podcast listening on the augmentation of subjective happiness and the enhancement of overall quality of life. The study\u27s primary objective is to scrutinize the intricate interplay between motivational factors and their impact on individuals\u27 subjective happiness and quality of life . This study has been done on 160 sample size among which 80 are podcast listeners and 80 are non- listeners. Through a meticulous analysis of patterns in podcast consumption, coupled with a profound investigation into the ensuing psychological outcomes, this research aims to shed light on the significance of motivational triggers in influencing individuals\u27 subjective happiness and the holistic assessment of their own lives. The analysis showed the positive relationship between motivation and its influence on subjective happiness and quality of life among podcasts listeners. By discerning the linkages between podcast motivation and positive psychological states, this study endeavours to provide insights that could contribute to designing interventions aimed at fostering greater well-being and enriching the overall quality of life for individuals who engage with podcast content
Comparative Analysis of Bleeding Frequency and Factor Utilization in Severe Hemophilia A and Hemophilia B Patients: Implications for Clinical Phenotype Variability
In haemophilia A and B, blood coagulants are reduced because of X-linked genetic factors. A study found that severe Haemophilia A (HA) tends to have a higher Hemophilia Severity Score (HSS) than severe Haemophilia B (HB). HA and HB patients were compared in terms of bleeding frequency and factor utilization. The data were collected from the records of our Haemophilia Clinic in a retrospective study conducted within a single institution. Hemophilia A and Haemophilia B were diagnosed in 88 and 16 subjects, respectively. A plasma-derived factor concentrate was administered on-demand to all of the patients. In this study, Chi-square, Man-Whitney U, and one-sample T tests were used. Version 12.1.4 of MedCalc Statistical Software was used for all calculations. Haemophilia A patients were admitted at a rate of 3.125 patients per year, while Haemophilia B patients were admitted at a rate of 0.77 patients per year (P 0.05). For haemophilia A patients, 3731500IU of FVIII (21201.704IU/patient/year) was used, whereas for haemophilia B patients, 611000IU of Factor IX (17457.142IU/patient/year) was used. The factor concentrations did not differ statistically significantly (P = 0.57). This study suggests Hemophilia A and Hemophilia B are inherited coagulation disorders that are clinically distinctive that differs depending on the severity of the disease. A recent study similar to ours also found results that are in agreement with ours
Understanding Threats to Campus Security in Baguio City and La Trinidad
Campus security continues to be an evolving field and keeping up with new information is as imperative as following the latest research in academic feat. Present day schools are faced with a multifarious issues and problems and no school is an exemption. In the study, the perceived threats to campus security of higher educational institutions along internal threat and external threat were considered. The data needed were gathered through the conduct of interview and themes were derived from the responses of the interviewee. In the study, it was found out that threats relating to campus security were encountered but has limited recognition from respondent schools. It was concluded that the administrators, faculty members and security guards does not have concrete understanding of the different threats to campus security. Organizational factors influence over security has obvious bearing on the appreciation of security threats and the mechanics on how to handle them effectively. If these factors are addressed, experiences of campus goers will virtually increase and experiences improve
The Nature of Execution Regarding the Object of Fiduciary Security: (Judicial Review of the Gorontalo District Court Judge\u27s Decision)
This research aims to: find out, analyze, explain and discover the essence of the execution of fiduciary collateral objects. Juridical analysis of the Gorontalo District Court Judge\u27s decision. The type of research in the results of this research uses empirical normative legal research methods. This research is a combination of a normative legal approach with the addition of various empirical elements. The normative-empirical research method focuses on the implementation of normative legal provisions (laws) in action on each particular legal event that occurs in a society. The research results show that the essence of the execution of fiduciary collateral objects is a guarantee of legal certainty and certainty of rights for creditors. The problems that occur must of course be based on the principles of justice and proportionality giving something in proportion. If you look at the many fiduciary cases that occur in the Gorontalo area, they are resolved more unilaterally by directly executing property rights against the debtor by the party. Creditors without going through a judge\u27s decision at the Gorontalo District Court, namely litigation in court, the results can be accounted for before the law because the court\u27s decision has valid legal force
Can Urethral Stricture be Treated Under Local Anesthesia?
Objectives : to evaluate the ability to treat mid urethral stricture under local anesthesia.
Material and Methods
A total of 15 patient aged 19 to 72 years old with lower urinary tract symptoms (LUTS) mainly poor stream and incomplete emptying , High post void residual urine on Ultra sound (Mindray DC30 hospital type) and low Q max (uroflow metery) , diagnosed as urethral stricture by urethrogram less than 1.5 cm were included in this study. Starting by insert 10-15 ml of lidocaine gel 5% in side urethra and waiting for 20 minutes then Checking cystoscopy done by C Mack karl stroz to diagnosis the urethral stricture and identifying urethral stricture then to passed hyderophilic guide wire ( indovasive nano glide straight tip size 0.032) to bladder and confirm its position in bladder with Ultra sound (Mindray DC30 hospital type) then gradually dilated the urethra with flexible dilators ( indovasive from 6 fr to 24 fr ) then rescope the patient to ensure potency of urethra with C Mack and finally inserted foley catheter 16 -18 fr keep it for 10 -14 days, and follow up patient with International Prostate Symptoms Score, PVR assessment by Us and Q max by flowmetery.
The study was approved by the ethical committee of the Iraqia Med school ….Written informed consent was obtained from all patients participating in the study. Patients were provided with a direct phone number to call in case of any bothersome adverse effects during the post operative period after dilation.
Data were entered and analyzed using SPSS version 25.
The IPSS symptoms score, PVR values and Q max were compared the study group before and after dilation Student paired-samples t-test using Numbers version 10.1 for MacBook pro2020.
Results
There were significantly decrease in overall PVR before and after ( mean PVR before dilation 218.6 ± cc ….and after dilation 12.8±cc…. p < 0,000000000027 ) and IPPSS before and after (mean IPSS before 20.5± cc …. IPSS after 9.33±cc… p < 0,000000000000031) . And significantly increase in Q max before and after ( mean Q max before 7.43±cc … after 20.2±cc…..p< 0,0000000000055) . All patient tolerate the dilation with no complication apart from little discomfort from foley which vanished with time.
Conclusion Mild urethral stricture can be treated under local anesthesia successfully with frequent dilation can avoid patient GA or Spinal anesthesi
Oral Health-Related Quality of Life in Children with Autism in Western Maharashtra
This study delves into the often overlooked realm of oral health-related quality of life in children with autism in Western Maharashtra. Autism, characterized by distinctive strengths and challenges affecting social interaction and communication, is a spectrum disorder with varying support needs. The overarching objective of this research is to comprehensively assess the oral health status and gauge the impact on the quality of life of children with autism, with a specific focus on parental perceptions. Conducted as a cross-sectional survey in June 2023, the study engaged 79 parents of children clinically diagnosed with autism. Employing a one-on-one interview format, participants responded to 20 questions addressing various aspects of oral health. The shortened version of the Parental-Caregiver Perceptions Questionnaire (P-CPQ) was utilized to measure oral health quality of life, encompassing domains such as oral symptoms, functional limitations, emotional well-being, and family distress. Results unveiled a nuanced landscape, with 40.5% of parents reporting their child\u27s oral health as average. Notably, 62% of parents expressed their child experiencing occasional oral pain, while 43% reported instances of bleeding gums. Significantly, 38% of parents admitted being upset due to their child\u27s oral health condition. These findings underscore the multifaceted challenges faced by families of children with autism, with oral health exerting a substantial impact on the physical, mental, and emotional well-being of both the child and their caregivers. In conclusion, this study contributes valuable insights into the intricate interplay between autism and oral health, shedding light on the broader implications for the quality of life of these individuals and their families. The research underscores the necessity for targeted interventions to address oral health issues and enhance the overall well-being of children with autism in Western Maharashtra
Study to Assess the Knowledge, Attitude and Practices of Additive Manufacturing Technology by Dental Practitioners in Dentistry across India- A Survey
This cross-sectional study aims to evaluate the awareness, understanding, and application of Additive Manufacturing Technology, specifically Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM), among dental professionals in India. The research involves 270 participants, comprising undergraduate and postgraduate students, dental practitioners, and dental lab technicians. The study reveals a notable 73.6% awareness of CAD/CAM technology among participants, emphasizing its potential applications across various branches of dentistry. However, a gap is observed between awareness and practical implementation, with only 39.7% of participants incorporating CAD/CAM systems into their clinical practices. Participants express a positive attitude toward CAD/CAM technology, with 90.5% indicating interest in installing such systems in their practices. Perceived limitations, including high-cost equipment and the need for extended training, are identified as key factors influencing the adoption of this technology. Comparisons with global studies highlight both similarities and variations in the knowledge and attitudes of Indian dental professionals regarding CAD/CAM technology. The study acknowledges its limitations, notably the small sample size, and recommends further research with larger populations and diverse variables across different regions of India. In conclusion, this survey provides valuable insights into the current status of CAD/CAM technology in Indian dentistry, offering a foundation for future research and potential strategies to bridge the gap between awareness and practical implementation in dental practices
Metabolic Reprogramming in Cancer: Targeting Energy Dysregulation
Cancer metabolism, a hallmark of tumorigenesis, signifies a fundamental shift in cellular energy utilization and biosynthesis. The altered metabolic phenotype in cancer cells, characterized by distinct adaptations in glucose, lipid, and amino acid metabolism, fuels the uncontrolled proliferation and survival of tumors. This review delineates the intricate interplay between metabolic reprogramming and oncogenesis, spotlighting pivotal mechanisms such as the Warburg effect, mitochondrial dysfunction, dysregulated lipid metabolism, and amino acid utilization.
Understanding these metabolic alterations offers insights into the intricate signaling networks and adaptations that sustain tumor growth, providing a foundation for novel therapeutic strategies. Targeting metabolic vulnerabilities emerges as a promising avenue, with potential interventions aimed at disrupting specific metabolic pathways in cancer cells. Additionally, the integration of metabolic profiling into precision medicine holds promise for tailoring therapies based on individual tumor metabolic phenotypes, thereby improving treatment efficacy and patient outcomes.
This review synthesizes current knowledge on cancer metabolism, elucidating its multifaceted implications in tumorigenesis and therapeutic interventions. Keywords: cancer metabolism, Warburg effect, mitochondrial dysfunction, lipid metabolism, amino acid utilization, targeted therapy
The Microbiome-Immune System Crosstalk: Impact on Overall Health
Human microbiome, a broad assortment of bacteria in diverse body regions, greatly affects immune responses and health. This study summarizes current knowledge of the microbiome-immune system interaction and human health. It shows how genetics, environment, and lifestyle shape the microbiome. Focus is on how the microbiome affects immune system development and function, highlighting the bidirectional relationship between microbial populations and immune cells. Dysbiosis is linked to inflammatory bowel illness, allergies, autoimmune disorders, and metabolic syndromes in the review. Probiotics, prebiotics, and fecal microbiota transplantation are discussed to modulate immune responses and treat related disorders. Finally, precision interventions, multi-omics integration, and ethical considerations are discussed as future promises and problems. This comprehensive analysis highlights the microbiome-immune system axis\u27s importance in human health and focused therapies