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Antioxidation, Antimicrobial, and Cytotoxic Activities of Some Mangrove Plants
No full textTwenty-three samples of mangrove plants were refluxed with methanol, then their activities were evaluated. Surprisingly, sample 6 (%SC50 = 5.00 ± 0.08 μg/mL) had the best antioxidation activity among candidates and L-ascorbic acid. Sample 19 was the second, with %SC50 = 5.15 ± 0.15 μg/mL. Both presented the availability of flavonoids and tannins, which was confirmed by phytochemical screening. The antimicrobial assay was done parallelly with the DPPH-free radical scavenging assay. Sample 19 exhibited the highest bacteriostatic activities against S. aureus, A. baumannii, P. aeruginosa (MIC = 62.50 μg/mL), and E. faecalis (MIC = 500 μg/mL) due to the presence of terpenes. In the MTT assay, it was found that sample 19 displayed specific toxicity against KB (%IC50 = 18.51 ± 5.49 μg/mL) and HeLa (%IC50 = 160.68 ± 39.36 μg/mL). Samples 2, 4, and 20 also demonstrated selective toxicity against cancer cells. This is the first report of sample 19, which is the most effective and potent cytotoxic agent against KB, and sample 4, which is the specific and most potent cytotoxic agent against HeLa. This is the first time mangrove plants have been evaluated for their potential to be alternative
natural sources of medicine
Kepercayaan Masyarakat Desa Bono Kabupaten Tulungagung Terhadap Pitungan Weton Dalam Pembuatan Keputusan Waktu Pernikahan: Perspektif Psikologi Budaya
No full textDalam tradisi budaya Jawa, pernikahan dipandang sebagai momen sakral sehingga untuk menentukan waktu pernikahan diperlukan perhitungan cermat melalui “pitungan weton”. Penelitian ini bertujuan untuk mengeksplorasi kepercayaan masyarakat Desa Bono, Kabupaten Tulungagung, terhadap “pitungan weton” dalam pengambilan keputusan waktu pernikahan dari perspektif psikologi budaya. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus, melibatkan dua partisipan yang dipilih melalui teknik purposive sampling. Data dianalisis secara tematik untuk menggali pemahaman mendalam terkait praktik ini. Hasil penelitian menunjukkan bahwa kepercayaan masyarakat terhadap “pitungan weton” tetap kuat hingga saat ini, dipengaruhi oleh nilai-nilai budaya, tradisi leluhur, dan keyakinan religius yang terinternalisasi dalam kehidupan sehari-hari. Temuan ini menyoroti bagaimana pitungan weton memberikan rasa aman psikologis dan menjadi mekanisme penguatan identitas budaya di tengah modernisasi. Implikasi
penelitian ini menggaris bawahi pentingnya menghormati kearifan lokal sebagai bentuk adaptasi budaya yang dapat dipertimbangkan dalam studi lintas budaya dan intervensi berbasis komunitas
Chat AI LLM (Large Language Model) di Universitas: Tinjauan Sistematis terhadap Variabel Pendorong Adopsi, Kerangka Teoritis, dan Tren Global
No full textKeberadaan chat AI berbasis Large Language Models (LLM) seperti ChatGPT telah banyak mempengaruhi pembelajaran mahasiswa di pendidikan tinggi. Penelitian terkait niat adopsi terhadap teknologi terus berkembang, namun tinjauan sistematis yang meneliti secara global mencakup variabel, kerangka teoritis, tren global masih terbatas. Maka dasar ini penulis membuat tinjauan sistematis dengan menggunakan PRISMA. Sebanyak 384 artikel di awal diambil menggunakan software publish & perish dari database Google Scholar, Scopus, Web of Science, dan PubMed (2020–2025). Kemudian disaring berdasarkan kriteria inklusi dan eksklusi menjadi 20. Kemudian di ekstrak, hasilnya menyoroti variabel yang sering dipelajari seperti intention to use, social influence, perceived usefulness, perceived ease of us, performance expectancy, effort expectancy, actual use, facilitating conditions, attitude, hedonic motivation, habit, enjoyment maupun trust. Faktor moderating yang sering dipakai yakni jenis kelamin, usia, dan tingkat pendidikan. UTAUT dan TAM adalah kerangka teoritis yang paling banyak digunakan. Studi dalam disiplin ilmu non-STEM jumlahnya lebih banyak daripada STEM, dengan Asia menyumbang publikasi terbanyak. ChatGPT mendominasi sebagai aplikasi Chat AI LLM utama yang diteliti. Analisis bibliometrik mengungkap empat kelompok kata kunci, dengan istilah yang sering digunakan oleh “chatgpt”, “student”, “use” dan “study”. Selain itu juga ditemukan 4 kluster pada network visualization. Tinjauan ini memberikan wawasan untuk penelitian mendatang terkait Chat AI LLM dalam pendidikan mahasiswa
The Role of Marketing Strategies for Improving Retail Coverage in West Bandung
No full textRetail coverage refers to the distribution range of retail products to various outlets or stores within a specific geographical area according to the determined target market. Retail coverage is a crucial aspect for companies to ensure their products are available in numerous stores and easily accessible to consumers. The objective of this research is to explain the role of marketing strategies in improving retail coverage in the West Bandung area. The impact of marketing strategies on retail coverage is evident through significant increases in the number of stores and sales. The research object is PT. Borwita Citra Prima's Bandung branch, specifically focusing on the West Bandung region. This study employs a qualitative descriptive research method with a case study approach. Data collection techniques employed in this research include observation, interviews, and documentation, while data analysis methods involve data reduction, data registration, conclusion drawing, and final verification of research validity through credibility tests. The results of this study demonstrate a significant impact on PT. Borwita Citra Prima's Bandung branch, particularly in the West Bandung area. This strategy can be implemented in other regions to improve retail coverage and reduce business burdens on wholesale stores
Legal Regulations on Gold Banks Post-UUP2SK and POJK17/2024: Normative Review and Comparison with International Practices
No full textThis article analyzes the legal framework for Indonesia’s bullion bank following the enactment of the Financial Sector Development and Strengthening Act of 2023 (UUP2SK No. 4/2023) and the Financial Services Authority Regulation No. 17/2024 (POJK17/2024). It also comparatively reviews gold banking regulations and practices in other countries to derive lessons for Indonesia. The research employs a normative juridical method, relying on primary legal sources (legislation and official regulations) and secondary sources (academic literature). The study indicates that UUP2SK formally recognizes bullion banking as a financial business activity related to gold, mandating Financial Services Authority (OJK) licensing for any institution engaging in such business. In response, POJK17/2024 establishes a comprehensive regulatory framework governing bullion bank operation, including the scope of activities (gold deposit-taking, financing, trading, custodial services, etc.), licensing procedures, capital requirements, and prudential principles. Internationally, countries like Turkey and Malaysia have successfully integrated gold banking into their financial systems—Turkish banks offer digital gold deposit accounts, and Malaysian banks provide online gold investment services under central bank oversight. Indonesia can learn from these experiences by enhancing public literacy, ensuring regulatory transparency, and building trust in gold-based financial products. With a robust legal framework in place and the first bullion bank licenses granted to state-owned Pegadaian and Bank Syariah Indonesia, Indonesia’s nascent gold banking sector holds significant promise. However, further refinement (i.e., clarifying tax treatment and strengthening consumer protection) is needed to optimize the implementation of the national bullion bank and to harness its potential for financial inclusion and economic growth
The Aspect of Restitution for Restitution and/or Compensation for Victims of Online Gender-based Violence in Indonesia’s Existing Regulation
No full textThe 2023 Annual Report of the Indonesian National
Commission on Women records that sexual violence is the dominant form of
violence against women, 2,228 cases or 38.21%. From this figure, a total of
1,697 complaints of Online Gender-Based Violence cases were received. The
overwhelming number of cases reflects the gloomy reality of law
reinforcement, specifically on cases of online gender-based violence in
Indonesia. This article aims to discuss the aspect of restitution and/or
compensation for victims of online gender-based violence in Indonesia
existing regulation. Several existing regulations on the handling of genderbased
violence are explored, then pinpointing the existence of restitution
and/or compensation within those regulations. This article argues that there
should be a synchronisation of articles among several interrelated regulations
in order to further and strongly signify the importance of restitution and/or
compensation for victims of online gender-based violence
Terobosan Baru Prediksi Heart Failure dari Single-Lead ECG: Masa Depan Skrining Jantung di Ujung Jari
No full textCustomer Trust, Engagement, and Swift Guanxi on TikTok Live Streaming
No full textWith the rapid advancement of social media, there has been a significant transformation, particularly among customers who interact with certain brands, exemplified by the phenomenon of live-streaming on TikTok. The interactions within this medium reflect a dynamic relationship between broadcasters and customers, in which mutual trust is essential to sustaining customer engagement. The present research examines the influence of customer trust on customer engagement. Furthermore, it analyzes the role of swift guanxi in strengthening relationships among TikTok live-streaming users in Indonesia. A quantitative approach was used, with a population comprising TikTok users who had made purchases and interacted with other community members, and a sample of 205 respondents selected via purposive sampling. Respondent data were analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM) to evaluate the measurement and structural relationships of the proposed model. The results showed that customer trust had a positive and significant effect on customer engagement, and swift guanxi also contributed to enhancing customer engagement. These findings indicate that interpersonal relationships between broadcasters and customers play an essential role in strengthening customer engagement on TikTok live streaming
