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    Breast Lump: A Rare Presentation of Tuberculosis in an Elderly Man

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    Introduction: Chest wall masses are caused by various entities and have diverse aetiologies. A careful history and physical examination are crucial to establish the correct diagnosis. Case report: A 77-year-old man presented with depressive mood, anorexia (weight loss of 20 kg) and a 1-month history of a non-painful breast lump with well-defined contours, which was about 6 cm in diameter. There was no history of trauma. Computed tomography of the thorax revealed a collection of liquid in the left anterior thoracic wall, associated with discontinuity of the 4th left costal cartilage, and upper left lobe cavitation, suggesting pulmonary tuberculosis. The patient was started on quadruple therapy with anti-tuberculosis drugs and discharged after a negative smear. Conclusion: In this case, the indolent onset of unspecific symptoms made it difficult to reach a diagnosis of pulmonary tuberculosis, which was confirmed by positive culture and imaging. A breast lump in an elderly patient with unspecific clinical manifestations is an unusual presentation of pulmonary tuberculosis. It is important to be aware of rib invasion and exclude tuberculosis in a patient with a chest wall mass. As tuberculosis is treatable, early diagnosis is vital as diagnostic delay can lead to contagion

    Erythroderma and Chronic Lichenification Due to Metformin

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    We present the case of a 62-year-old man with a 4-year history of pruritus and erythroderma. The patient had been taking metformin for 5 years, so after contact allergies, contact with toxic products, and autoimmune diseases were ruled out, the condition was treated as erythroderma secondary to metformin. A skin biopsy subsequently confirmed the diagnosis and lichenification of some areas of the patient's skin

    Acquired von Willebrand Syndrome and Chronic Anaemia: A Different Diagnostic Approach

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    Heyde’s syndrome is a form of acquired von Willebrand syndrome that consists of bleeding from intestinal angiodysplasia in the presence of aortic stenosis (AS). An association with obstructive hypertrophic cardiomyopathy, rather than AS, by a similar mechanism has also been described. We report the case of a 78-year-old woman with chronic anaemia and hypertrophic obstructive cardiomyopathy in whom intestinal angiodysplasia with active bleeding was identified by an unconventional method. In this case, the authors describe a different approach to reach the correct diagnosis

    Land Suitability Assessment of Green Infrastructure Development A Case Study of Pendik District (Turkey)

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    Urban green space, an integral part of urban ecosystems, provides important environmental and social services that mitigate environmental problems caused by rapid urbanisation and urban sprawl. Urban planning and policy aim at optimising the benefits obtained from urban green spaces. The analytic hierarch process (AHP) is a commonly used technique for suitability assessment of land uses. The traditional AHP method is criticised for its subjectivity and uncertainty. Considering this, Fuzzy-AHP has been introduced as an advanced methodology in dealing with the uncertainty in the decision making process. In this study, we compared the two methods of AHP and fuzzy-AHP integrated with geographic information systems (GIS) for the suitability assessment of Pendik district, Istanbul regarding green space development. First, criteria and sub-criteria were determined and the corresponding weights were assigned based on literature and experts’ knowledge. This is followed by preparation of spatial maps integrated with the corresponding weights and development of final suitability maps in both methods of AHP and fuzzy-AHP. Our results show that high suitability areas are mainly distributed in the southern part of Pendik district around the existing urban green infrastructure. In both maps obtained from AHP and fuzzy-AHP, more than 30 percent of the study area has the potential for green space development

    A Circular Economy Approach to Fish Oil Extraction

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    Fish oil rich in polyunsaturated omega-3 fatty acids is extracted in high yield from anchovy filleting waste using d-limonene as green biosolvent in a simple solid-liquid extraction performed by mechanically stirring and maceration followed by limonene removal via evaporation under reduced pressure. As limonene is renewably obtained from waste orange peel, this method closes the materials cycle and establishes a circular economy process to obtain high quality fish oil from biowaste available worldwide in several million t/year amount. Significant economic, social and environmental benefits are anticipated

    The MEV project: A new high-resolution telescope for the Muography of Etna Volcano

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    The Muography of Etna Volcano (MEV) project aims at developing a high-resolution muon telescope for the muography of the summit area of the Etna volcano. A muon tracking telescope, based on plastic scintillation strips with WLS fibers embedded and photomultipliers readout, was built and tested during 2017. The telescope is composed of three 1 × 1 m2 position sensitive planes and the total angular aperture is about ±45◦, with an angular resolution not exceeding 0.4 msr. During the design of the detector, a special effort was devoted to mechanics and electronics in order to build a detector able to face the harsh conditions at the top of a high mountain. This paper summarizes the features of the first telescope prototype already operating at the top of the Etna volcano and the results of the test phase which lasted from January to July 2017

    First characterization of the detector system for the XAFS beam-line of the synchrotron light source SESAME

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    A Fluorescence Detector System for X-ray Absorption Fine Structure (XAFS), composed of 8 monolithic arrays of Silicon Drift Detectors (SDDs), each having 8 cells of 9 mm2 area, is being realized within the INFN ReDSoX Collaboration. It will be used for X-ray absorption spectroscopy at the Jordanian synchrotron light source SESAME, which provides a photon beam with an energy range between 3 and 30 keV. Detailed characterization tests at Elettra Sincrotrone Trieste have demonstrated an energy resolution at the Mn 5.9 keV Ka line, for the monolithic array, below 170 eV FWHM at room temperature

    The Cerenkov Telescope Array project status

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    The Cherenkov Telescope Array (CTA) represents the next generation ground-based observatory for gamma-ray astronomy at very-high energies. It will be capable of detecting gamma rays in the energy range from 20 GeV to more than 300 TeV with unprecedented precision in energy and directional reconstruction. CTA will be located in the northern hemisphere at La Palma, Spain, and in the southern hemisphere at Paranal, Chile, and will comprise more than 100 telescopes of three different types. CTA will be one of the largest astronomical infrastuctures in the world with open data access and it will address questions in astronomy, astrophysics and fundamental physics in the next decades. In this contribution we will present the status of the CTA construction, discuss the telescope prototypes, highlight the scientific perspectives and the instrument performances

    Flavor mixing, neutrino oscillations and neutrino masses

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    We discuss mass matrices with four texture zeros for the quarks and leptons. The three flavor mixing angles for the quarks are functions of the quark masses and can be calculated. The results agree with the experimental data. The texture zero mass matrices for the leptons and the see-saw mechanism are used to calculate the matrix elements of the lepton mixing matrix as functions of the lepton masses. The neutrino masses are calculated: m1 ≈ 1.4 meV, m2 ≈ 9 meV, m3 ≈ 51 meV. The neutrinoless double beta decay is discussed. The effective Majorana neutrino mass, describing the double beta decay, can be calculated - it is about 5 meV. The present experimental limit is 140 meV

    Search for vector-boson resonances decaying to a top quark and a bottom quark with the ATLAS experiment at LHC

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    A recent search for heavy resonances, namely W bosons, decaying to a top quark and a bottom quark with a lepton and missing transverse momentum plus jets in the final state is presented. The analysed data come from proton-proton collision and correspond to an integrated luminosity of 36.1 fb−1 collected with the ATLAS detector at the Large Hadron Collider at √s = 13 TeV. No significant excess of data over the Standard Model prediction is found and the results are expressed as upper limits on the W → t¯b production cross-section times branching ratio as a function of the W boson mass. The production of right-handed W bosons is excluded at 95% confidence level for masses below 3.15 TeV. A prospect for this search at the high luminosity LHC is also reported, showing the expected sensitivity for an integrated luminosity of 3000 fb−1 and a centre-of-mass of √s = 14 TeV

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