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Recurrent Haemoptysis Revealing Hughes-Stovin Syndrome
Hughes-Stovin syndrome is a very rare condition with no defined diagnostic criteria. We present the case of a 26-year-old man who had haemoptysis revealing Hughes-Stovin syndrome. We will consider the aetiology, therapeutic and evolutionary aspects of this disease
Blood Culture-negative Endocarditis Caused by Tropheryma whipplei: Whipple’s endocarditis
Case description: A 67-year-old man was admitted with progressive heart failure due to blood culture-negative endocarditis of the aortic valve. Urgent aortic valve replacement was needed. Polymerase chain reaction (PCR) testing of samples of the explanted aortic valve revealed Tropheryma whipplei. The patient received ceftriaxone, followed by long-term co-trimoxazole. Recent arthralgia may have been a diagnostic clue.Conclusion: Whipple’s endocarditis should be considered in patients with arthralgia and blood culture-negative endocarditis (BCNIE)
Efficacy of Cannabinoids on Spasticity and Chronic Pain in a Patient with Co-occurrence of Multiple Sclerosis and Neurofibromatosis Type 1
Neurofibromatosis type 1 (NF1) is a rare autosomal dominant disease involving the skin and central nervous system (CNS), and also characterized by skeletal and spinal schwannomas that may cause chronic neurogenic pain. Furthermore, pain in NF1 is underestimated, even though it has an impact on quality of life. Multiple sclerosis (MS) is the most common acquired demyelinating disease that may in later stages present with refractory spasticity, particularly in the lower limbs. Oromucosal cannabinoid sprays are currently available for spasticity treatment in MS, with encouraging results on MS pain, but few data have been reported regarding the use of cannabinoids in NF1. We report the successful treatment of chronic neurogenic pain and spasticity in a patient with co-occurrence of NF1 and MS after a poor response to standard approaches
Colon Ischaemia Induced by Amoxicillin-related Anaphylactic Shock
Colon ischaemia is the most frequent type of ischaemia of the digestive tract. It is more common among the elderly, especially patients with haemodynamic disturbance. In young patients, it is associated with particular drugs such as oral contraceptives and ergotamine derivatives. Anaphylaxis is characterized by acute onset and skin and mucosal involvement together with cardiovascular involvement. Gastrointestinal symptoms are common in anaphylaxis, but gastrointestinal bleeding and acute colon ischaemia are rarely described. Here, we present the case of a 52-year-old woman with acute ischaemic colitis associated with an anaphylactic reaction to amoxicillin
Antiche e moderne tecnologie: l’applicazione delle tecniche di rilevamento tridimensionale per la rappresentazione e l’analisi dei manufatti litici
In the past few years, the application of digital techniques to archaeology has strongly increased, including 3D recording of lithic artefacts for purposes of documentation and analysis. In this paper, the main acquisition techniques are reviewed focusing on their application to lithics, and on the cost-benefit analysis which largely depends on the research objectives. The introduction of the main functions of the virtual approaches to lithics comes from the new possibilities offered in the area of graphic documentation. In fact, 3D models could gradually replace the archaeological drawing thanks to the data objectivity and to the ability to undergo remote analysis. Indeed, in virtual models complex metric data and technological information are easily recorded. Furthermore, 3D models allow the application of quantitative and statistical analysis for different aims, such as reduction intensity estimation and geometric morphometrics, especially thanks to the landmark-based approach. All these potentials have been already explored in recent years, some of them have produced a considerable number of publications. However, this diversification needs the sharing of Open Data protocols in order to evaluate the methods, as well as the application of integrated approaches. Some examples of integration between traditional and 3D analyses derive from traceology and refitting studies, where the virtual tool is not considered as replacing but complementary. Finally, the options in the fields of data storage and cataloguing have been addressed, besides the free circulation of 3D models for academic and museological purposes, including 3D printing
Archaeological survey of the western boundary strip of Iran through using remote sensing techniques
A huge irrigation project is being conducted in the Iranian western border and satellite investigation of the area was initially performed in order to identify archaeological settlement sites before they were threatened by the so-called Garmsiri water project. Because of the diverse geography and the inherited critical war conditions such as mined lands, the investigation of ancient sites in this region is not easy; therefore, satellite-based methods can play an important role in the detection and documentation of archaeological sites. The main hypothesis of this study is that all settlements have internal and external characteristics allowing to detect the presence of archaeological sites. The identification of a series of these characteristics in a spatial area will lead to the discovery of archaeological sites. Three general methods which this study utilizes to identify the location of the site include: 1) Identification using satellite images; 2) Identification using the predictive model based on GIS; 3) Integration of satellite images data applying the prediction model. Thereby, those points having a series of internal and external characteristics related to settlement sites were introduced as potential ancient sites. In the field survey, 57 points were confirmed as settlement sites. The perspective of this study helps archaeologists to explore the surface and subsurface remnants of ancient sites without conventional field-walking survey
The contribution of artificial intelligence to aerial photointerpretation of archaeological sites: a comparison between traditional and Machine Learning methods
On the basis of the research activity carried out as part of the Archeo 3.0 project ‘Integration of key enabling technologies for the efficiency of preventive archaeological excavations’, the authors explore the feasibility and limits of the automated approach for the recognition of archaeological marks. This approach is mainly motivated by the relevance that aerial photographs play in the reconstruction of ancient topography of human settlements. For this aim, a collection of historical aerial photographs of both the city and the necropolis of Vulci has been considered. These photographs, in colour and B/W, have been previously used in a PhD thesis in Ancient Topography in which the traditional methodology (photointerpretation and cartographic restitution) has been fully exploited. In this work, a systematic study is presented in order to compare the results obtained with Machine Learning techniques vs traditional ones. This comparison allows us to discuss the strengths and limits of both methodologies
Misurazioni digitali non invasive di spolia veneziani: innovazioni di metodo e proposte di applicazione
For the first time in the history of Venetian archaeology, this paper presents the innovative potential of the application of a non-invasive digital technique for the extensive measurement of reused sculpture (spolia) preserved in Venice and its lagoon, both in architectural contexts and as freestanding structural elements. The sample measurements were carried out to get precise digital representations of archaeologically and epigraphically meaningful items, such as ancient columns, capitals or inscriptions, which are reused in the facades of palaces on the Grand Canal, as well as inside and outside Venetian churches and bell-towers. In most cases, measurements were taken for the first time; it was also possible to test the functions of the device over considerable distances, even greater than 50 m, thus obtaining the measurement of artefacts that are difficult to access. Finally, the provision of a very detailed dataset made it possible to set up a broader, albeit still embryonic, study of the proportions of ancient artefacts, especially inscriptions
Optical microprofilometry optimized for surface analysis and 3D printing of archaeological objects
In this paper we investigated the application of the optical scanning micro-profilometry based on conoscopic holography sensors for the acquisition and the surface analysis of archaeological objects with a micrometric resolution. The portability of the setup developed and its modularity allow to work in situ with a multi-scale and multi-material approach. In addition, we have developed our own tools to create a mesh from the 2D-arrays of distances collected with the resulting possibility to obtain a replica of the artwork using 3D printing technologies. We test the microprofilometer on two case studies: a fragment of an archaeological amphora, also presenting the workflow to obtain the 3D printed object, and an Etruscan bronze mirror, analyzing its surface
La vita umana come bene disponibile
L'articolo affronta problemi sollevati dalla questione se la vita umana sia o meno un bene disponibile. Descrive quindi le due tesi opposte e le principali ragioni etiche, religiose e giuridiche che le sostengono. Mostra come la tesi dell'indisponibilità della vita comporti un maggior numero di problemi. Indica infine nella tesi disponibilista la formula più adatta per una convivenza democratica fra i due fronti, per un equo bilanciamento fra valori in conflitto e per una maggiore garanzia di stabilità sociale