Ardabil University of Medical Sciences
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A Case Report of Cerebellar Hemangioblastoma in Dr.Fatemi Hospital of Ardebil
Get PDFA case report of cerebellar hemangioblastoma in Dr.Fatemi Hospital of Ardebil Introduction: Hemangioblastoma is one of the vascular benign tumors of the central nervous system, which is most commonly seen in the cerebellar hemispheres, but Other much less common sites of primary CNS tumors include brainstem and spinal cord.
Case report:A 57-year-old male without any family history of hemangioblastoma presented with headache, diminishing vision and increased intracranial pressure.
Funduscopy showed bilateral papilloedema. MRI imaging techniques confirm the existence of a tumor in the posterior cranial cavity and cerebellum. The patient's
MRI report shows a solid cystoid mass in the left hemisphere of the cerebellum and a vasogenic edema around the mass compressing the fourth ventricle.The patient was
undergoing surgery and the tumor was removed and sent to the pathology for final diagnosis. Pathologic results indicate cerebellar hemangioblastoma.
Conclusion:The cerebellar Hemangioblastoma is benign tumor, detected by imaging techniques, such as MRI.Surgical resection is the choice treatment for
Hemangeoblastoma
Hepatotoxicity After Exposure to Tebuconazole: A Case Report and Brief Review
Get PDFA 48-year-old man was admitted to our hospital with complaints of productive cough, anorexia, and sweating from two weeks ago. Laboratory studies revealed an increased level of liver enzymes. The work-up of serological markers was negative for both infectious and non-infectious causes of hepatitis. He denied smoking, alcohol consumption, occupational exposures, and illicit drug use. Interestingly, he had a history of contact with an antifungal toxin called tebuconazole about 15 days before admission. In toxicological examinations using gas chromatography with a nitrogen-phosphorus detector, the cause of poisoning was revealed to be fungicide tebuconazole. To confirm the causal relationship between toxin and hepatitis, exposure avoidance and repeated testing were considered. Complete recovery was achieved in all clinical symptoms and laboratory findings. We suggest that tebuconazole-induced hepatitis should be considered in farmers exposed to this fungicid
Relationship between migraine and hypertensive disorders of pregnancy
Get PDFAim: Preeclampsia is a pregnancy-specific syndrome associated with vascular spasm and endothelium dysfunction that leads to reduced organ blood flow. Migraine is a syndrome of benign recurrent headaches, nausea, vomiting, or other signs of neurologic dysfunction. Some studies have shown that women who have a history of migraines during pregnancy are at high risk of preeclampsia.
The aim of this was determine the relation between migraine and hypertensive disorders of pregnancy.
Material and Methods: In this case- control study, cases consisted of 100 women with preeclampsia, and controls were 100
normotensive women. All women were hospitalized in Ardabil city hospital and all of them were evaluated for any history of migraine.
The two groups were matched for confounding factors. The data were collected by questionnaire including demographic, medical, obstetrics, and migraine assessment sections. Data were analyzed by statistical methods using SPSS version 19.
Results: The mean age of women in study group was 28.12±6.50 and in control group was 25.2±5.75. Majority of persons in the study, were in age group16 to 35 years old and their education levels were high school graduates and they were housewives. The
mean of BMI was 24.8. Of people, 11% were suffering from migraine. The history of migraine in the study group was 16% and in the control group was 6% and the difference was significant between two groups (p=0.001). History of migraine headaches in patients with hypertensive disorders was 2.65 times more than women in control group.
Conclusion: Results showed that migraine headaches to be associated with gestational hypertension and history of any migraine could be as a risk factor for PE /gestational hypertension (GH) in future
Relationship between Serum Vitamin D Level, Interferon Alpha and Psychological Disorders in Patients with SLE (Systemic Lupus Erythematosus
Get PDFBackground: In different studies, the correlation between systemic lupus erythematosus (SLE) and disease activity with vitamin D has been shown. Also, low level of vitamin D and interferon alpha was associated with psychological disorders but there wasn’t more evidence about the relationship between vitamin D deficiency and psychological disorders.
Objective: This study aimed to investigate Relationship between serum vitamin D level, interferon alpha and psychological disorders in patients with SLE.
Methods: In this cross-sectional descriptive study, 50 SLE patients were recruited. Serum 25-OH Vitamin D concentration and IFN-α levels and also, levels of SLEDAI were measured. Statistical methods were used to determine the correlation between vitamin D and IFN-α and also the correlation between INF-α with Depression, Stress and Anxiety scores in SLE patients.
Results: Vitamin D deficiency (<40 nmol/L) was detected in 20% of SLE patients. The mean Vitamin D and INF-α in SLE patients was 23.94 ± 11.93 and 396.60 ± 54.73, respectively. There was significantly negative correlation between vitamin D and depression (r=-0.479, p=0.001) and Anxiety (r=-0.34, p=0.01) but the relation between vitamin D and stress wasn’t significant. Of all SLE patients, 56% had depression, 64% had anxiety and 66% had stress in very severe level.
Conclusion: Results showed that the level of vitamin D was negatively correlated with depression and anxiety of patients. Also, it seems that, by increasing the QOL of patients and decreasing the rate of depression and anxiety in SLE patients we could improve the vitamin D level and then SLEDAI
Clinical and Histopathological Features of Pediatric Space Occupying Central Nervous System Tumors in the Ardabil Bou’Ali Hospital, Northwest of Iran in a 12 -Year Period
Get PDFBackground and Objectives: Pediatric central nervous system (CNS) tumors are the second most common childhood malignancy after leukemias and the most common solid tumor. The incidence rate of childhood primary CNS tumors in the United States is approximately 5.67 per 100,000 person-years. Their comparative prevalence among other cancers in one hand, the potentially threatening nature of involving a developing system and quite vague symptoms particularly in younger children in the other hand make them more noteworthy.
Methods: We performed a case series study of space occupying tumors with the neuronal origin in Ardabil Bou’ Ali children’s hospital, north west of Iran. A total of 20 confirmed cases according to the revised WHO histological types since the foundation of our hospital for 10 years were collected. All the cases were then classified and analyzed for the relative frequency, the initial symptoms, and detailed location of tumors.
The primary manifestations were placed in the 3 main categories: symptoms suggesting raised intracranial pressure, focal neurological deficits, and nonspecific ones. Evidences of abducent nerve palsy and hospitalization for chemotherapy adverse effects were the other instances.
Results: The most frequent type of CNS tumors was optic glioma, followed by medulloblastoma, and neuroblastoma beside 5 PNETs. The two cases, one brain and one spinal tumor had not been confirmed pathologically for the parental dissent to biopsy. 8 out of 10 intracranial tumors had revealed intracranial hypertension and the all 6 cases of optic gliomas had signs of 6th cranial nerve palsy. Cytopenia, pneumonia and oral ulcers were the commonest causes of hospitalizations without chemotherapy.
Conclusion: The relative frequency of our tumors corresponded to international reports. Moreover, symptoms due to intracranial hypertension and esotropia representing abducent palsy were predominant which warns carful evaluating for a child with these signs or symptoms specially in the youngers who cannot probably communicat
The Relationship Between Social Support and Depression in Patients with Breast Cancer
Get PDFIntroduction: The relationship between social support and depression can have implications for the outcome of breast cancer treatment. Therefore, the aim of this study was to examine social support and its relation to depression in women with breast cancer.
Methods: In this descriptive-correlational study performed in Tabriz in 2018. A total of 240 patients with breast cancer who met the inclusion and exclusion criteria were included in the study. The Multidimensional Scale of Perceived Social Support (MSPSS) and Beck Depression Inventory were used for research purposes. The Spearman correlation test was used to determine the relationship between the two variables. A P value of < 0.05 was considered significant.
Results: 63% of women had moderate to severe depression, and mean ± SD of total social support score was 40.29 ± 11.99. Spearman’s correlation results indicated a negative relationship between depression and social support (r = -512, P < 0.001).
Conclusion: The prevalence of moderate to severe depression in the current study sample was high (63%), which is consistent with similar studies. On the other hand, women with below average depression had higher perceived social support score, and the correlation between these variables was statistically significant
Evaluation of addition of spearmint in common diet of patients with PCOS that Referred to Ardabil's women's diseases clinic
Get PDFBackground and Objective: Polycystic Ovary Syndrome (PCOS) is a common and complicate endocrine disorder which it's prevalence in fertility age is 4 -20 percent. Although different treatment has been undertaken, no cure has ever found for PCOS. One of the common drugs taken by most patients is Metformin. Having numerous side effects preventives taking this medication. Spearmint is a complementary approach in order to treat this disorder which can effectively control clinical symptoms in PCOS like Hyper androgenism, Acne and hirsutism.
Materials and Methods: This study is a clinical trial. The targeted women population aged 16-40 with PCOS. The mentioned clinical trial was conducted on 62 persons of women during the age of fertility in 16 up to 40 and randomly was chosen to be divided in two groups of 31 persons. One group was treated by 1500 mg of Metformin as TDS. Metformin was started a quarter (1/4) daily and was reached to 3 tablets as TDS and this approach was continued up to 3 months. The second group was treated by 1500 mg of Metformin as TDS along with 3 Spearmint soft gels (60 mg/day) in 3 months. The sample people were followed in 3 months treatment period from the beginning of the study and prescribing the medication. The pursuance of patients was carried on by taking the basic information and demographic of both groups and then Sonography was observed and clinical checkup was done and afterwards, women were checked up monthly in 3 later months and check list which was already provided previously, were filled out. When the 3 month period was over, the second Sonography was taken from the same women and was examined by different categories like having or not having cysts, regular menstruation and any hirsutism and clinical symptoms. Collected data was coded and analyzed in SPSS 23rd edition software which descriptive statistics, graphs, charts and tests were illustrated by. Obtained results from both groups were compared in order to get a better medication with lower side effects to cure PCOS.
Results: outcomes indicated that in both groups, menstruation was more regular and the number of cysts was decreased which was clear in sonography results. No significant difference was observed in the Ferriman-Gallway Score. The comparison between the obtained results cleared that statistically no difference existed between two groups which, it meant adding the complimentary herbal Spearmint didn't make any considerable change in curing with a common treatment of Metformin
Effects of Motivational Interviewing on Adherence to Treatment Regimens Among Patients With Type 1 Diabetes: A Systematic Review
Get PDFBackground. Motivational interviewing (MI) is a strategy for promoting adherence to treatment regimens among patients with diabetes. However, limited evidence exists regarding its effectiveness in reducing A1C.
Objective. To identify and synthesize evidence about the effectiveness of patient, provider, and health system interventions to improve diabetes care
among patients with type 1 diabetes.
Design. This was a systematic review of randomized controlled trials.
Methods. A search was conducted of the scientific databases MEDLINE, Elsevier, CINAHL, Google Scholar, ProQuest, Ovid, and PubMed without imposing any time limit. Only four documents met the inclusion criteria and were included in the final analysis. The methodological quality of these
four articles was reviewed by three reviewers using the Jadad Scale. The main
intervention and the primary outcome in this study were MI or motivational enhancement therapy and A1C, respectively.
Results. The retrieved studies reported that MI promotes self-monitoring of blood glucose and reduces A1C.
Conclusion. MI is effective in enhancing patients’ adherence to the treatment regimen and thereby decreasing A1C. Given the fact that the reviewed studies had not eliminated the effects of confounding factors, further studies
are needed to assess the pure effects of MI on adherence to treatment regimens and A1C level