Ardabil University of Medical Sciences

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    Evaluation of the efficacy of the Natinal Early Warning Score (NEWS) in predicting the mortality of stroke patiants admitted to intensive care units

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    Background: NEWS is a tool used to identify patients at risk. Scores are based on initial clinical observations, including: heart rate, respiration rate, systolic blood pressure, oxygen saturation, level of consciousness, body temperature, and oxygen support. Few studies on NEWS evaluation have been conducted to date and no study has been conducted in Iran. Aim: This study examines the power of NEWS in predicting the mortality of patients admitted to the ICU who are in fact in a more critical condition. Methods and material: Ninety patients for whom a definitive diagnosis of CVA was presented based on the set of symptoms and paraclinics were included in the study. For patients both male and female and in any age group and with any underlying disease with a definitive diagnosis of CVA at the beginning of admission to the ICU and up to the first 24 hours of admission of all parameters in NEWS measured and evaluated and for each patient according to this measurement Completed. NEWS score was calculated for each patient and patients based on NEWS scores in three groups of high risk (total scores greater than or equal to 7), moderate risk (total scores 5-6 or 3 scores from just one parameter) and low risk (total scores zero or 1-4) Were located. Results: There was a significant relationship between systolic blood pressure, oxygen demand, heart rate and level of consciousness with patients' discharge status (P 0.05). Conclusion: Finally, it was concluded that there is a significant relationship between clinical risk based on NEWS scoring and patients' discharge status, which indicates a significant increase in mortality in patients with higher NEW

    Letter to the editor on: F. Campostrini et al. Association between acute histopathological changes of rectal walls and late radiation proctitis following radiotherapy for prostate cancer

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    We have read with great interest the recent report by Campostrini et al. that prospectively evaluated the effect of acute histopathological changes (HC) of the rectum on development of radiation-induced late clinical proctitis (LCP) following prostate cancer external beam radiotherapy (EBRT) [1]. We would also like to thank the authors for sharing the wonderful work. After a mean follow-up of 10.3 years, the 10-year incidence of grade 2 or greater LCP was 12.9% (20/70 patients). The univariate and Kaplan–Meyer methods indicated that there is a significant association between the gland (or crypt) loss in the anterior rectal wall (ARW) and LCP. Accordingly, the authors concluded that a substantial loss of glands in the mucosa of the ARW with doses ≥60 Gy is a significant predictor of grade ≥2 LCP. As suggested in the study, the mean dose received by the ARW should be ≤48–52 Gy with conventional fractionation (2 Gy/fraction), resulting in reduced LCP. In this context, we would like to point out the following interventions to reduce the ARW dose as much as possible

    Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study

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    Background While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disability that can occur in an injury, and must provide estimates with sufficient demographic, geographical and temporal detail to be useful for policy makers. The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet these criteria. Methods In this study, we report and discuss the methods used in GBD 2017 for injury morbidity and mortality burden estimation. In summary, these methods included estimating cause-specific mortality for every cause of injury, and then estimating incidence for every cause of injury. Non-fatal disability for each cause is then calculated based on the probabilities of suffering from different types of bodily injury experienced. Results GBD 2017 produced morbidity and mortality estimates for 38 causes of injury. Estimates were produced in terms of incidence, prevalence, years lived with disability, cause-specific mortality, years of life lost and disability-adjusted life-years for a 28-year period for 22 age groups, 195 countries and both sexes. Conclusions GBD 2017 demonstrated a complex and sophisticated series of analytical steps using the largest known database of morbidity and mortality data on injuries. GBD 2017 results should be used to help inform injury prevention policy making and resource allocation. We also identify important avenues for improving injury burden estimation in the future

    Patients’ expectations of fixed orthodontic treatment(before treatment) in Ardabil during 2019-2020

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    Introduction: It is very crucial to understand patients’ expectations of the method of treatment, the related problems, treatment period, and the frequency of visiting sessions. This study attempted to determine the patients’ expectations of fixed orthodontic treatment (before treatment) in Ardabil in 2019-2020 Materials and methods : This cross-sectional study was carried out at the clinic of Dentistry Faculty of Ardabil University of Medical Sciences and several private orthodontic clinics in Ardabil. The data was collected using the standard questionnaire by Mirzaei et al. (2018). Moreover, the data was analysed using Chi-squared, Mann-Whitney, and Kruskal-Wallis tests on SPSS version 22 with P less than 0.05 considered significan Results: The results of this study showed that patients’ expectations of the first orthodontic treatment session were oral hygiene, explanation of the treatment plan, and dental radiography, respectively. The highest expectations of orthodontic patients were malocclusion, jaw disorders, and bracket attachment; the least expectations were jaw surgery and tooth extraction. Correct positioning of teeth a beautiful smile were the patients’ main expectations of orthodontic treatment. Most of the patients expected that the treatment period would be about one year or one and a half years and examination sessions would be every six weeks. Furthermore, the results showed that there was no significant difference based on gender in patients’ expectations of orthodontic treatment, treatment period, and frequency of examination sessions (P>0.05). In addition, there was no significant difference based on age and income in patients’ expectations of orthodontic treatment period (P>0.05). However, there was a significant difference based on age and income in some questions about patient’s expectations of orthodontic treatment and frequency of examination sessions. Nonetheless, there was no significant difference in most of the questions (P>0.05). Conclusion: : It was concluded that the correct positioning of teeth and a beautiful smile were the patients’ main expectations of orthodontic treatment and there was no significant difference based on gender, age, and income in most of the questions

    Association Between Oxidative Stress, Serum Antioxidant Status and Vitamin D in Asthmatic Children

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    Introduction: The role of vitamin D in prevention of many diseases have been confirmed by many studies recently. The aim of this study was to determine the levels of oxidative and anti-oxidative markers after administration of vitamin D in asthmatic children. Methods: This randomized clinical trial study has been done on 60 asthmatic children who randomly divided into two groups. One group group received a single dose of vitamin D (5000 ng/ml) and another group received placebo with the same dose in the form of prescribed vitamin D. The levels of 25 (OH) D were measured at the baseline and also levels of vitamin D, glutathione peroxidase 1 (GPx1) and Total Oxidative Capacity (TOC) were measured 10 days after prescription single dose of vitamin D. Results: The amount of Vitamin D at baseline in two drug and placebo groups were similar but at the end of 10 days in the drug group with 54.8±20.92 significantly higher than placebo group with 30.73±12.98. The GPx1 levels at the end of 10 days in the drug group with 44.2±30.9 significantly more than placebo group with 29.5±12.9. Overall TOC amount at the end of 10 days in the drug group with 15.29±3.38 IU was similar to placebo group with 15.06±3.53 IU. The levels of vitamin D in rural children was significantly more than urban children. Conclusion: The results showed that, vitamin D could significantly increase the amount of GPx1, hence it can be used as an appropriate drug in the treatment of asthmatic children

    Job Safety Risk Assessment in the Printing Industry using Job Safety Analysis method and offering control recommendations

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    Background: Nowadays, one of the most important problems in various industries is work-related accidents that put a lot of costs on the industry. Aim: To assess the risk of duties of employees of a printing house by occupational safety analysis method (JSA) also, to provide appropriate control solutions. Methods: This descriptive cross-sectional study was conducted in one of the printing industries in Iran in 2020. Information was collected in the JSA checklist through visits, observations, and interviews with staff. Then the stages of the work were determined, and the existing or potential hazards (ergonomic, electric, chemical, and mechanical) related to each stage were identified and determined. The risk level of each activity was determined according to the MIL-STD-882E standard. Results: In these eight stages, twenty-three risks were identified, of which ten risks were undesirable, and eleven risks were acceptable with the need for revision. Also, two risks were acceptable while no revision was required for it. The stage of transporting cargo to the warehouse with four hazards was the highest. Besides stapling and working with the sewing machine, each with two hazards gained the lowest number of hazards in risk assessment. Conclusion: The main hazards identified in this study are mechanical hazards that teaching ergonomic principles to individuals, using the safety and ribbed shoes, carrying two people, and observing the principles of manual handling can be useful to reduce or control these types of hazards

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