Ardabil University of Medical Sciences
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Psychometrics Properties of Social Well-Being Scale in Iranian Elderly
Get PDFAbstractIntroduction:Today, following the aging population, the elderly have been faced with various social issues. The social well-being and health of the elderly are important but it has been neglected that is closely related to the quality of life. The Social Comfort Scale has notbeen validated in the Iranian elderly. The purpose of this study was to investigate the Psychometrics properties of Social Well-being Scale in Iranian Elderly.Methods:This is a psychometrics properties study. The participants were 550 elderly people living in Tehran who were randomly selected from health centers. The study was conducted on the Social Well-being Scale. The data were analyzed using descriptive statistics and Pearson correlation test, exploratory factor analysis, and Cronbach's alpha via SPSS v.22 software.Results:Participants were 58.9% male and 41.1% female. The mean age was 66.09 ± 6.67. Alpha Cronbach's was 0.94. Structural validity by exploratory factor analysis showed that SWS consisted of five components (social integration, social acceptance, social contribution, social actualization, and social coherence).Conclusions:Social Well-being Scale has good reliability and validity in Iranian elderly. Therefore, it can be used to assess the social well-being and health of Iranian elderly
Insecticide Susceptibility Status of Wild Population of Phlebotomus kandelakii and Phlebotomus perfiliewi transcaucasicus Collected from Visceral Leishmaniasis Endemic Foci in Northwestern Iran
Get PDFBackground: Phlebotomus kandelakii and Phlebotomus perfiliewi transcaucasicus sand flies are the vectors of visceral leishmaniasis in Iran. The aim of this study was to evaluate the susceptibility of Ph. kandelakii and Ph. perfiliewi trans-caucasicus, collected from an endemic focus of visceral leishmaniasis (VL) in the northwest of Iran, to different select-ed insecticides.
Methods: Sand flies were collected from the villages of Meshkinshahr and Germi Counties using light traps and aspira-tors from May to October 2019. The sand flies were identified as Ph. kandelakii and Ph. perfiliewi transcaucasicus us-ing standard identification keys. Susceptibility test was carried out against DDT (4%), Malathion (5%), Propoxur (0.1%) and Lambda-cyhalothrin (0.05%) according to the WHO standard method. MedCalc statistical software was employed to calculate LT50 and LT90 and to compare the chances of sand flies surviving the exposure to the studied in-secticides.
Results: A total of 1,278 female specimens were used for the susceptibility tests. Out of which 1,063 samples were used for the test and 215 for the control group. The estimated LT50 values for DDT (4%), Malathion (5%), Propoxur (0.1%), and Lambda-cyhalothrin (0.05%) for Ph. kandelakii were 15.1, 13.4, 15.4 and 5.8 minutes respectively, and for Ph. per-filiewi transcaucasicus were 11.9, 15.6, 15.9 and 5.8 minutes respectively.
Conclusion: This susceptibility studies revealed different LT50 values for different insecticides efficient against Ph. kandelakii and Ph. perfiliewi transcaucasicus. The regular monitoring for the resistance of Ph. kandelakii and Ph. per-filiewi transcaucasicus sand flies seems necessary in diseases control programs in this area
Seroepidemiological study of toxocariasis using ELISA method in children aged 5-15 years in Ardabil, in 1398
Get PDFBackground and Objective: Toxocariasis is a parasitic disease caused by infection with a group of toxocara nematodes from the roundworm branch. The most common cause is Toxocara canis. The dog is the main host of this worm and the worm eggs enter the environment through the dog's feces. If a human, as a random host, infects the parasite's eggs with contaminated water and food, the eggs open in the intestine and the larvae are released. The larvae can penetrate the intestinal wall and migrate through the blood and lymph vessels to the liver, brain, eyes, and other tissues. These larvae can not mature and remain wandering in different tissues for months. The larvae are metabolically active and cause a severe inflammatory reaction
Aim: Because this disease causes a lot of economic and health damage in the world and it is necessary to know it from a health and economic point of view and also shows that in recent years not only the prevalence of the disease in the world has not decreased but also in many countries, It is spreading in humans and animals, so it was decided to design and conduct a study to investigate the prevalence of this disease.
Methods: 472 samples from health centers were collected and evaluated by ELISA test. The test results were read by ELISA reader and the results above 0.43 were considered positive and values below 0.43 were considered as negative.
Results: The mean age of these individuals was 11.47±2.84 years. There was a statistically significant relationship between the age of the participantes and the incidence of toxocariasis. There was a statistically significant relationship between gender and the incidence of toxocariasis. There is a direct link between where people live and how they get toxocariasis. There was a significant relationship between contact with dogs and their incidence of toxocariasis. (P=0.001). In the study of clinical symptoms of the subjects, in individuals whose light absorption rate was above 0.43 and positive, a statistically significant relationship was observed between the clinical symptoms and the result of ELISA test (P = 0.001). In individuals with a positive result, the relationship between vegetable consumption and the result of ELISA test was statistically significant.
Conclusion: In our studies, the results showed that there is a direct relationship between the age of the subjects and the incidence of toxocariasis. The incidence was higher in boys than girls. Toxocariasis had a direct and significant relationship and also a statistically significant relationship was observed between the consumption of vegetables in the subjects and the incidence of toxocariasis
Comparison of sexual function and some factors affecting in women with and without breast cancer
Get PDFBackground: Breast cancer is the most common cancer among women and has the highest mortality rate among women worldwide. Among the problems that arise with the progress of treatment in breast cancer are issues related to quality of life. This disease can be an important factor in causing sexual problems due to the weakening of physical strength, reduced ability to perform daily activities, hospitalization of the patient and the resulting depression. Because breast cancer is the most common cancer in women and affects one of the most important female genitals. Therefore, the study of sexual and marital problems in breast cancer patients is extremely important. Therefore, this study was designed to determine the extent and type of sexual dysfunction and some factors affecting it in these patients and compare it with healthy women.
Aim: To determine sexual function and some factors affecting it in women with and without breast cancer.
Methods and material: A total of 80 healthy women and 80 women with breast cancer treated were included in the study. Data were collected using Demographic Information Questionnaire, Female Sexual Function Index (FSFI) and Post-Breast Body Image Questionnaire (BIBCQ).
Results: 160 people were included in the study who were divided into two groups of 80 people (healthy and sick). The mean age of the healthy group was 38.41 years with a standard deviation of 7.29 years and the mean age of the patient group was 39.46 years with a standard deviation of 5.46 years. Of sexual function variables; Sexual desire, psychological stimulation, moisture, satisfaction and sexual pain showed a significant difference between the affected and healthy groups (P <0.05). There was no significant difference between orgasm index between the two groups (P <0.05).
Conclusion: Sexual function is higher in healthy individuals than in patients with breast cancer. In terms of body image, this finding had a higher score in people with higher education, which indicates a higher level of concern about body image in this group of people. Also, in the patients who were employed, a higher score was obtained than the unemployed and housewives, and showed that the employed patients were more concerned about their body image
Synthesis and biological assessment of ciprofloxacin-derived 1,3,4-thiadiazoles as anticancer agents
No full textThe quinolone-3-carboxylic acid scaffold is essential structure for antibacterial activity of fluoroquinolones such as ciprofloxacin. Modification of 3-carboxylic functionality in this structure can be used for switching its activity from antibacterial to anticancer. Accordingly, a series of C-3 modified ciprofloxacin derivatives containing N-(5-(benzylthio)-1,3,4-thiadiazol-2-yl)-carboxamide moiety was synthesized as novel anticancer agents. Most of compounds showed significant activity against MCF-7, A549 and SKOV-3 cancer cells in the MTT assay. In particular, compounds 13a-e and 13g were found to be as potent as standard drug doxorubicin against MCF-7 cell line (IC50s = 3.26–3.90 µM). Furthermore, the 4-fluorobenzyl derivatives 13h and 14b with IC50 values of 3.58 and 2.79 µM exhibited the highest activity against SKOV-3 and A549 cells, being as potent as doxorubicin. Two promising compounds 13e and 13g were further tested for their apoptosis inducing activity and cell cycle arrest. Both compounds could significantly induce apoptosis in MCF-7 cells, while compound 13e was more potent apoptosis inducer resulting in an 18-fold increase in the proportion of apoptotic cells at the IC50 concentration in MCF-7 cells. The cell cycle analysis revealed that compounds 13e and 13g could increase cell portions in the sub-G1 phase, inducing oligonucleosomal DNA fragmentation and apoptosis confirmed by comet assay
The Relationship of General Health Condition with Safety Attitudes and Demographical Specifications in Workers of Car after-Sale Services Workshops Iran 2019
No full textBackground: Health condition of workers affects their productivity. The relationship between general
health and safety attitudes is not quite clear.
Objective: The present paper is an attempt to examine the relationship of general health condition with
safety attitude and demographical specifications of workers at car after-sale services workshops in Ardabil-
Iran.
Materials and Method: The study was carried out as a descriptive-analytical cross-sectional study. The
sample group consisted of 650 workers in small car after-sale services workshops located in Ardabil City.
Three questionnaires including a demographical form, the General Health questionnaire (GHQ-28), and the
safety attitude inventory were used for data gathering. The collected data was analyzed in SPSS19.
Results: The mean score of safety attitude was 71.05±2.3 and the mean score of general health was
24.96±3.35. The score of general health had a significant relationship with age group, work experience,
marital status, education level, and history of work incident. The mean scores of safety attitude was
significantly different depending on age group, work experience, workshop ownership status, marital status,
education level, income, and history of work accident.
Conclusion: The subjects had a low safety attitudes score and high probability of general heath disorders.
General health condition was directly related to safety attitude of the participants. Therefore, providing
applied educations based on the workers’ needs to increase awareness and improve safety attitudes of
workers can lead to a decrease in the rate of work accidents and a higher general health in the workers
Assessment of Health and Safety Hazards in Hospitals using five methods and comparing the results with the FMEA method
No full textPsychometric Properties Of The Pieper-Zulkowski Pressure Ulcer Knowledge Test among Nurses Working In Medical- Educational Centers Of Ardabil City,2018
Get PDFObjective: To evaluate the psychometric properties of the Pieper-Zulkowski Pressure Ulcer Knowledge Test (PZ-PUKT) in Iranian nurses.
Methods: The present study is a methodological study. A convenience sample of 323 nurses and 161 nursing students from Ardabil University of Medical Sciences, Ardabil, Iran were entered to the study. To determine the psychometric properties of the PZ-PUKT content and differential validity, item analysis (difficulty and discriminative indices), internal consistency and test-retest were performed. SPSS ver.15 was used for data analysis.
Results: As the total score of PZ-PUKT in critical care nurses (39.84±7.10) was higher compared to general nurses (37.01±8.47) and nursing students (24.59±12.95) the differential validity of the tool was confirmed. The mean difficulty indices of questions with and without considering the option of “I don't know” were 0.53 and 0.65, respectively. Also they were 0.27 and 0.13 for discriminative index. Cronbach's alpha coefficient was 0.92 for the 72-item PZ-PUKT. Correlation coefficient between test and retest in 30 nurses was 0.81.
Conclusions: This study showed that Persian version of PZ-PUKT is valid and reliable for using in Iranian society. It can be used in education and research to assess nurses' knowledge as well as to evaluate the effectiveness of training programs on prevention and care of pressure ulcers
Need, seeking and utilization of health services among elderly in Ardabil -2019
Get PDFBackground: The increase in the elderly population in future years in Iran, the country's health system will face a serious challenge that can be managed in part by improving the function of service delivery based on benefit studies in the elderly population.
Aim: In the present study, we evaluated the types of elderly needs and how to address and solve the problems related to them in the city of Ardabil and evaluated the type of needs and effective factors in addressing them in detail.
Methods: The study population of the elderly in Ardabil was covered by the comprehensive health centers of Ardabil, which according to the latest national census in 2016, the elderly population of Ardabil is about 15 thousand people. The final sample size was 553 = 0.6 * 331, which finally entered the final stage of analysis after 291 incomplete questionnaires were dropped. Cluster random sampling method was used for sampling. From the comprehensive urban health center and rural bases of Ardabil city, 20 urban units were randomly selected and from the elderly population covered by each center and base, 15 elderly people (two clusters) were selected and the questionnaire was completed by referring to the door.
Results: In our study that was performed on 291 elderly people in Ardabil. 222 (76.3%) were male and 69 (23.7%) were female. In terms of age distribution, the highest number with 126 people (43.3%) belonged to the age group of 65 to 69 years. More than 70% of the elderly in our study in the past month mentioned the need for outpatient health services, which was higher among men (73.4% vs. 62.3% in women) and with age. It was more. The highest sense of need was mentioned in the group with armed forces insurance (82.4%). The elderly who had supplementary insurance felt significantly more in need than those without supplementary insurance (75.1% vs. 63.2%). In terms of the need for inpatient services during the past year, the highest sense of need was observed in men (48.2% vs. 27.9% of women). The results showed that men felt more need for inpatient services (P = 0.029, OR = 4.41) and outpatient services (P = 0.018, OR = 3.955) than women. The results also showed that having insurance other than health insurance increases the search and benefit of services (P = 0.002, OR = 0.283).
Conclusion: The aim of this study was to investigate the feeling of need, search and benefit of outpatient and inpatient services by the elderly in Ardabil. Finally, the present study showed that more than 70% of the elderly felt the need for outpatient services, of which more than 98 Percentage went to receive services and about 84% had benefited from the services. The study showed that obstacles such as lack of insurance coverage, belief in self-medication, etc. prevented full use of services. Based on this, it was found that older men with insurance other than health insurance felt more in need than other groups, and in terms of using services, men showed a better chance of using services than women. Accordingly, it is necessary to consider special policies for the elderly in order to remove the barriers to the use of services based on variables such as facilitating access to services and increasing insurance coverag
Challenges and Strategies for Implementing Evidence-Based Practice in Nursing: a Systematic Review
Get PDFIntroduction: Many nurses are incapable of implementing evidence-based practice as a problem-solving approach in the field of health care. Therefore, the purpose of this study was to summarize and report structurally the results of various studies conducted in this field to identify challenges and strategies for implementing evidence-based practice in nursing to develop effective and efficient guidelines.
Methods: In this systematic review study, using the internal database: Magiran, SID, Iranmedex and foreign: CINAHL, ProQuest, Ovid, PubMed, Scopus, Science Direct, Google Scholar all articles published in Iran in 2010 to 2020 in the field of Evidence-based practice were explored. The result of this research was the achievement of 39 articles and a research project related to the subject, which eventually 19 completely related studies are included in the research.
Results: Among the studies reviewed, 3 articles (16%) were published in foreign journals and 16 articles (84%) in domestic journals. The results represent four main concepts include: "Evidence-Based Practice Features", "Evidence-Based Practice Barriers", "Evidence-Based Practice Strategies" and "Evidence-Based Practice Instructions".
Conclusion: According to the results, most nurses are not familiar with the concept of evidence-based practice and there are several barriers in the way of nurses in implementing evidence-based practice. To address the clinical challenges of nursing, health care managers and policymakers should plan to use nursing professors and graduate students with the support of nursing managers to guide nurses in the implementation of evidence-based practice and the development of protocols