Ardabil University of Medical Sciences
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Factors Affecting Fatigue in Patients with Type II Diabetes Mellitus Referring to Ardabil Diabetes Clinic
Get PDFBackground & objectives: Fatigue is a common complaint in patients with type 2 diabetes, which can affect self-care behaviors and people's efforts to control diabetes. This study was conducted to determine the severity of fatigue and its related factors in patients with type 2 diabetes.
Methods: In this descriptive-correlational study, 218 patients with type 2 diabetes mellitus who were referred to diabetes clinic of Imam Khomeini Hospital in Ardabil in 2017 were selected by available sampling. Data were collected by five questionnaires including: socio-demographic form, Fatigue Questionnaire, Pittsburgh Sleep Quality, Beck Depression, and Visual Analogue Scale. Data analysis was done by using descriptive (mean, standard deviation and frequency) and Inferential statistics (Pearson correlation coefficient, simple and multiple regression model) in SPSS software v22.
Results: The mean fatigue score of the participants was 57.07±17.16, which indicated moderate fatigue. Pearson correlation test revealed a significant correlation between fatigue and pain (r=0.440 p<0.01), depression (r =0.590, p<0.01), Number of complications of the disease (r=38.0, p<0.01), Duration of diabetes (r=0.21, p<0.01), duration of exercise (r=-0.305, p<0.01), and sleep quality (r=0.390, p<0.01). However, no significant correlation was found between fatigue and glycosylated hemoglobin and BMI. Data analysis using multivariate linear regression showed that four factors of pain, depression, duration of disease, and duration of exercise were predictors of fatigue in patients with type II diabetes.
Conclusion: The present study showed that fatigue was a relatively common problem in patients with type 2 diabetes and factors such as pain, depression, duration of disease and duration of exercise were factors that affect fatigue. Health care providers need to pay special attention to fatigue assessment in patients with diabetes and proper interventions be taken to reduce pain and diagnosis and control depression in these patients
The Correlation between Educational Services Quality and Responsibility from the Viewpoint of the Students of Ardabil Nursing and Midwifery Faculty
Get PDFBackground & objectives: A desirable quality of educational services and training of responsible human resources are two tasks of the educational system. The current study aimed to determine the relationship between the quality of educational services and responsibility in students of Ardabil nursing and midwifery faculty.
Methods: A correlative study was conducted on 329 students of Ardabil nursing and midwifery faculty, 2017. Data were collected using the SERVQUAL and standard questionnaires for educational services quality and responsibility, respectively. Data were analyzed statistically using independent t-test and one-way ANOVA by SPSS-15 software.
Results: The mean age of students was 21±3.06 years. The majority of students were female (54.7%), mostly studying nursing (32.5%) and in the second year of education (35.8%). The mean and standard deviation of educational services quality and responsibility scores were 3.07±0.25 and 3.97±0.05, respectively. Pearson correlation coefficient showed a significant statistical relation between educational services quality score and responsibility (p<0.0001, r=0.013).
Conclusion: Considering the direct and significant relationship between the quality of educational services and responsibility, paying attention to these items through improving the educational services quality and training of responsible studentscan increase the efficacy of students in clinical environments
Treatment Effect of Ergocalciferol on Bone Metabolism Indexes and Parathyroid Hormone in Hemodialysis Patients
Get PDFIntroduction. Vitamin D deficiency is a common problem in end-stage renal disease patients under hemodialysis. Both active and nutritional vitamin D supplementation have been recommended for its treatment. In this study we aimed to evaluate the effects of treatment with ergocalciferol on bone metabolism indexes in hemodialysis patients.
Materials and Methods. In a randomized controlled trial, 40 hemodialysis patients were randomly allocated to the intervention (n = 20) and placebo (n = 20) groups. During the study, 4 patients in the placebo and 1 in the intervention group were excluded. Patients received calcitriol, 0.25 mg/d, with ergocalciferol, 50 000 IU, or placebo weekly for 3 months. Serum levels of 25-hydroxyvitamin D, calcium, parathyroid hormone, and alkaline phosphatase were measured before and after treatment.
Results. 25-hydroxyvitamin D levels were significantly improved in the intervention group (12.00 ± 4.90 ng/mL versus 29.89 ± 9.48 ng/mL, P .05). There was no significant changes in serum calcium, parathyroid hormone, or alkaline phosphatase levels in each group. Eight patients (42.1%) in the intervention compared to zero cases in the placebo group had normal 25-hydroxyvitamin D levels after treatment (P = .004). No cases of hypercalcemia were seen in the studied patients.
Conclusions. Treatment with ergocalciferol could significantly improve vitamin D deficiency with no significant effects of serum calcium or parathyroid hormone levels
Relationship between Spiritual Health and Happiness of Students
Get PDFBackground and Aim: Spiritual health and happiness both are of the most important aspects of the psychology and have a significant role in the development of educational purposes. The objective of this research is examination of relationship between spiritual health and happiness among students of Ardabil Nursing Midwifery Faculty.
Materials and Methods: This descriptive- analytical study was done in 2017 in Ardabil Nursing Midwifery Faculty. The sample size was 90 respondents based on Cochran formula. Data was collected by using Ellison spiritual health and Oxford happiness questionnaires. The results were analyzed by spss18 and descriptive (frequency and percentage) and analytical (person correlation coefficient, independent t- test, ANOVA) statistics methods.
Findings: There was a significant positive relationship between spiritual health of students with their happiness (p≥0.001, r= 0/543).The score men of spiritual health got 64.41±5.90 in students and score men of happiness got 86.98 ±14.22. Also, All dimensions of spiritual health had significant relationship with happiness.
Ethical Considerations: After explanation about the study objectives and ensuring confidentiality of information, the participants' consent was obtained.
Conclusion: With regard to direct relationship between spiritual health and happiness, instructional managers with planning for students' spiritual health, can provide settings to increase students' happiness
Evaluation of evolutionary status of children with congenital hypothyroidism treated with levothyroxine
Get PDFBackground and objective: Congenital hypothyroidism is one of the most common preventative evolutionary disorders in newborns and children, which, if not treated promptly, leads to mental retardation and developmental disorders. The aim of this study was to investigate evolutionary status of children with congenital hypothyroidism treated with levothyroxine.
Methods: In a historical cohort study, 78 infants (44 boys and 34 girls) with congenital hypothyroidism under treatment with were evaluated by the ASQ questionnaire for their developmental status.
Results: Out of the total number of subjects examined, 32 were impaired and 46 were healthy in ASQ questionnaire. The results showed that 11 children had temporary congenital hypothyroidism and 67 had permanent congenital hypothyroidism. The results showed that there was no significant difference among the studied children in terms of height, weight, birth weight, maternal age, number of tests performed each year, average TSH is the first year of treatment, gender, place of residence, education and parental relationship. There was a significant correlation between number of visits at age 2 only in children 3 years old, the outcome of the ASQ test and the age of diagnosis and treatment initiation, the evolutionary status of the children in terms of the initial dose of treatment showed a significant difference between the two groups.
Conclusion: According to the findings of this study, it can be concluded that neonatal screening is one of the most successful health programs in the country, and the detection and initiation of hypothyroidism in neonates as soon as possible leads to a reduction in the evolutionary disorder in these children
Awareness and attitudes towards epilepsy in Ardabil medical and non-medical university students
Get PDFBackground: Epilepsy is a common neurologic disease that caused many problems such as more costs and social problems due to negative attitudes to disease for patients. This study aimed to evaluate the knowledge and attitudes of medical and non-medical students toward epilepsy in Ardabil city, Iran.
Materials and Methods: A cross-sectional descriptive survey was conducted in Ardabil city (Northwest of Iran) in 2017. 150 students selected randomly from all medical and non-medical students that completed the self-administered questionnaire which provided for this study. Collected data analyzed by statistical methods in SPSS version 19.
Results: Of all students, 30% were girls and rests of them were boy. Of all students, 47.3% had moderate knowledge and 44.7% had well attitudes about epilepsy. Most of boys with 51.1% and most of girls with 45.7% had moderate knowledge but no significant difference between two sexes. Most of boys with 43.8% and most of girls with 46.7% had moderate attitudes towards epilepsy but no significant difference between two sexes.
Conclusion: Results showed that most of students in this study had moderate knowledge and good attitudes towards epilepsy
Data of adsorption of Basic Blue 41 dye from aqueous solutions by activated carbon prepared from filamentous algae
No full textFor this data article the adsorption of Basic Blue 41 (BB 41) dye by activated carbon derived from filamentous algae (AAC) of available in agriculture waste as cheap adsorbents were examined. Activated carbon has been widely used as an adsorbent regard to its massive specific surface area, high porosity, reusability and thermal stability for the removal of pollutants from effluent. These filamentous algae grow widely in irrigation streams, causing decreasing speed of water flow and are not even eaten by livestock so are considered agricultural wastes. They can be used as precursors for activated carbon preparation and as adsorbent for the dye removal. The data of initial dye concentration (50–200 mg//L), pH of dye solution (3–9), adsorbent dosage (0.25–2 g/L), and contact time (5–200 min), were assessed. The structure of AAC was characterized by X-ray diffraction and Fourier transforms infrared spectroscopy. Activated carbon with a 94% removal of dye at concentration of 100 mg/L, pH 9, and adsorbent dose 1 g/L after 90 min. The data of isotherms and Kinetics indicated that the experimental data are fitted to Langmuir and second-pseudo-order models. Under the optimum conditions, maximum adsorption capacity of the AAC in Langmuir model enhanced to amount of 125 mg/g. According to the experimental data, filamentous algae are a suitable raw material for activated carbon production
The Effect of Bone Marrow Mesenchymal Stem Cells on the Granulocytic Differentiation of HL-60 Cells
Get PDFObjective: Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into a variety of cell types. They control the process of hematopoiesis by secreting regulatory cytokines and growth factors and by the expression of important cell adhesion molecules for cell-to-cell interactions. This investigation was intended to examine
the effect of bone marrow (BM)-derived MSCs on the differentiation of HL-60 cells according to morphological evaluation, flow cytometry analysis, and gene expression profile.
Materials and Methods: The BM-MSCs were cultured in Dulbecco’s modified Eagle’s medium supplemented with 10% fetal bovine serum (FBS). After the third passage, the BM-MSCs were irradiated at 30 Gy. To compare how the HL-60 cells differentiated in groups treated differently, HL-60 cells were cultured in RPMI-1640 and supplemented with 10% FBS. The HL-60 cells were seeded into six-well culture plates and treated with all-trans-retinoic acid (ATRA), BM-MSCs, or BM-MSCs in combination with ATRA, while one well remained as untreated HL-60 cells. The expression levels of the granulocyte subsetspecific genes in the HL-60 cells were assayed by real-time polymerase chain reaction. Results: Our results revealed that BM-MSCs support the granulocytic differentiation of the human promyelocytic leukemia cell line HL-60. Conclusion: Based on the results of this study, we concluded that BM-MSCs may be an effective resource in reducing or even preventing ATRA’s side effects and may promote differentiation for short medication periods. Though BM-MSCs are effective resources, more complementary studies are necessary to improve this differentiation mechanism in clinical cases
Fourth Update on the Iranian National Registry of Primary Immunodeficiencies: Integration of Molecular Diagnosis
No full textThe number of inherited diseases and the spectrum of clinical manifestations of primary immunodeficiency disorders (PIDs) are ever-expanding. Molecular diagnosis using genomic approaches should be performed for all PID patients since it provides a resource to improve the management and to estimate the prognosis of patients with these rare immune disorders.
Method
The current update of Iranian PID registry (IPIDR) contains the clinical phenotype of newly registered patients during last 5 years (2013–2018) and the result of molecular diagnosis in patients enrolled for targeted and next-generation sequencing.
Results
Considering the newly diagnosed patients (n = 1395), the total number of registered PID patients reached 3056 (1852 male and 1204 female) from 31 medical centers. The predominantly antibody deficiency was the most common subcategory of PID (29.5%). The putative causative genetic defect was identified in 1014 patients (33.1%) and an autosomal recessive pattern was found in 79.3% of these patients. Among the genetically different categories of PID patients, the diagnostic rate was highest in defects in immune dysregulation and lowest in predominantly antibody deficiencies and mutations in the MEFV gene were the most frequent genetic disorder in our cohort.
Conclusions
During a 20-year registration of Iranian PID patients, significant changes have been observed by increasing the awareness of the medical community, national PID network establishment, improving therapeutic facilities, and recently by inclusion of the molecular diagnosis. The current collective study of PID phenotypes and genotypes provides a major source for ethnic surveillance, newborn screening, and genetic consultation for prenatal and preimplantation genetic diagnosis
Data Quality Assessment in Emergency Medical Services: What Are the Stakeholders’ Perspectives
Get PDFIntroduction: Emergency care is usually conducted within limited time and with limited resources. During emergency care processes, data quality issues should be taken into account. The aim of this study was to assess the quality of emergency care data from the perspectives of different data stakeholders.
Method: This survey study was conducted in 2017. In this research, the viewpoints of three groups of data stakeholders, including data producers, data collectors, and data consumers, were collected regarding data quality in emergency care services. Data were collected by using a standard information quality assessment questionnaire.
Results: The mean values for each dimension of data quality were as follows: sound data (6.23), dependable data (6.28), useful data (6.30), and usable data (6.35), with 0 being the lowest possible score and 10 being the highest. The role gap analysis suggested a clear gap between data producers and data customers at the university level.
Conclusion: Overall, data quality in emergency medical services was not at a high level. Although data quality was improving, the levels of data completeness, compatibility, and usability were low. To improve the usability of emergency medical service data, more attention should be paid to the dimensions of accuracy, completeness, and consistency of data sources