Ardabil University of Medical Sciences
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Comparison of the Body Image Between Women Seeking Female Genital Cosmetic Surgery and Women Not Interested in FGCS: A Case Control Study
Get PDFObjectives: Although body image has been investigated in a variety of cosmetic surgeries, this study was the first research in Iran to examine the mental image of women seeking female genital cosmetic surgery (FGCS).
Materials and Methods: The participants of this case-control study included a total of 163 women of reproductive age, who referred to the specialized gynecological clinic of Alavi hospital in Ardebil during February 2016 to July 2017. Of these participants, who were selected through convenience sampling, 83 were willing to undergo FGCS while the other 80 were not interested in this kind of surgery. Then, they were evaluated for pelvic organ prolapse. A questionnaire containing demographic questions as well as a body image questionnaire were used to collect the required data.
Results: The total mean (standard deviation) body image score in the case and control groups was 237.2 (22.3) and 241.7 (23.1), respectively, indicating that no significant difference existed between the 2 groups. Regarding the components of body image, no significant difference was observed between the 2 groups in terms of body-self relations (P = 0.101) and body weight perception (P = 0.521). However, a significant difference was observed in terms of the mean body satisfaction score (P = 0.004).
Conclusions: Women interested in FGCS had less body parts satisfaction compared with those not willing to undergo this surgery. This can be useful in providing necessary consultations and trainings regarding the wide range of variation in natural appearance of the female genitalia for women willing to undergo these types of surgeries
Relationship between Medical Therapy Tourism and the Rate of Tourism Attraction in Ardabil Province
Get PDFBackground & objectives: Health tourism is one of the types of health service trades. Iran has high potential in developing this field. The aim of the current study was investigating the relationship between medical curative tourism and the rate of tourism attraction in Ardebil province.
Methods: current study was an applied one with descriptive-analytical method of study. Samples were statistically estimated and study setting included 8 public and 2 private hospitals, mineral spas, residential places (hotels, inns and guest rooms) of Ardebil. Data gathered using a check list prepared by the researcher regarding the terms and regulations of the centers for health tourism, an standard checklist of evaluation of the international patients unit medial institution of Ministry of Health that its face validity approved by the experts. To implement the field research, 3 samples of each hospital with total of 30 check-lists and 99 controls were prepared by health tourism experts of the university, funding department of the hospital and the researcher. For data analysis, Cosmograph-Smirnov test used to determine the normality and multi-variable regression and Pearson Correlation test used to measure the relationship between variables using SPSS Statistical software.
Results: Results of the study indicated that the highest and lowest mean were related with having general qualifications of tourism attraction (1.85) and lower costs and ability to communicate (1.26), respectively. Among variables of medical therapy tourism (country status, condition of hospitals, medical team condition and the mineral spas condition), the general condition of the hospitals and the condition of medical team had no meaningful relationship with the rate of tourism attraction. Therefore, the general hypothesis was confirmed that there was a significant relationship between medical tourism and the rate of tourism attraction in Ardebil province (p<0.01). Variables of country status (0.67) and spa location (0.70) determined the relationship in prediction of medical therapy tourism attraction.
Conclusion: Results of the study indicated that among different factors of country status, condition of hospitals, medical team and the mineral spas, the factor of hospital condition due to the lower gradation and standards of the Ardebil hospitals and the factor of medical team condition due to poor understanding and awareness of the medical team of the regulations and their poor ability in obtaining the required skills, no significant relationship found between medical tourism and the rate of tourism attraction in Ardebil province. Therefore, it is suggested that the authorities in the field of health and tourism help in more development of this industry by providing the necessary substructures of this sector and execution of macro politics
The Relationship between Organizational Innovation and Organizational Performance with the Mediating Role of Intellectual Capital in the Civil Registration Office of Ardabil Province
Get PDFAbstract:
The importance of registry and the rapid environmental changes have forced the above organization to consider innovation in the delivery of services as an important task to preserve survival. Accordingly, the present study is investigating the relationship between organizational innovation and organizational performance with the mediating role of intellectual capital in registry office of Ardabil province. Based on the purpose, the method used in the present study is applied. In terms of collecting and executing method, it is descriptive and in terms of the type of collected data, the present study is of quantitative type. The statistical population consists of all 190 employees of registry office in Ardabil province. Using Morgan formula, ,101 people was selected. They were randomly categorized and the elements within each class were selectedin the same way. In this research, standard questionnaires of organizational innovation of Hang et al., organizational performance questionnaires of Hersey and Goldsmith and intelectual capital questionnaires of Bontis was used. Also, descriptive analysis was done using SPSS software and in order to test research hypothesis, Lisrel software was used. The results indicate that organizational innovation and intellectual capital through the mediating variable of intelectual capital have positive and significant effect on organizational performance
Investigating the Role of Organizational Identity in the Organizational Transparency and Financial Performance of Rural Cooperatives in Ardabil Province
Get PDFThe purpose of this research is to investigate the role of organizational identity on organizational transparency and financial performance of rural co-operatives in Ardebil province. It is a field research and is of descriptive and correlational type. The statistical population of this study includes all employees of rural cooperatives in Ardebil province that were over253 people that from which a sample of122 people was selected using Morgan method by applying stratified random sampling method. In this study, organizational transparency questionnaires, financial performance questionnaires, organizational identity questionnaires were used. The data were analyzed using SPSS21 software and the multivariate and simple regression analysis was used to discover the relationship between the data and rate of it. It should be noted that in this research, the index of curvature has been used to determine the normality of the data. Generally, according to the results of the study, it was found that organizational identity had a significant effect on organizational transparency and financial performance. The results also showed that the dimensions of employee membership and employee loyalty had a significant effect on organizational transparency and performance of employees. The component of employee similarity did not have any significant effect on organizational transparency, also staff membership and staff similarity have no meaningful effect on financial performance
Using intravenous acetaminophen in the reduction of opioids in spinal cord surgeries by patient-controlled analgesia
Get PDFBackground: Proper management of postoperative pain results in improved quality of patient's' life, early postoperative recovery, reduced hospitalization period and decreased treatment costs. Regarding significant efficacy and higher pain relief functions, opioids are amongst the best pain relief drugs. However, use of theses narcotics as pain killers is somehow controversial. Current study investigated the effects of IV acetaminophen in reduced use of opioids in surgeries of spinal cord by PCA method.
Methods: Current double blinded clinical trial study performed upon 86 patients of 20-70 years of age who candidate for spinal CD implant with ASA class I or II. Patients randomly divided into two groups of IV Acetaminophen therapy (N=43) and placebo group (N=43) and each group were put equally under general anesthesia in which both received pain pump containing Fentanyl during recovery. Patients were examined regarding pain score, amount of opioid use and request for extra narcotics and the related complications including nausea, vomiting, dizziness, allergy, gastrointestinal bleeding and Ileus every 6 hours for 24 hours and the obtained results were recorded.
Results: Regarding VAS, pain was significantly lower during 24 hours of study in IV Acetaminophen group (p<0.05). Mean use of opioid via pain pump was significantly lower in IV Acetaminophen group compared with placebo group (p=0.00). Request for extra doses of narcotics was higher in placebo group while regarding demand for extra pain relief, there was no significant difference between both groups. Regarding other results, no significant difference observed between both study groups.
Conclusions: Results of the study indicated that use of a combination of IV acetaminophen along with opioids would be much more effective than use of narcotics alone in postoperative pain control of CD implant surgery of spinal cord and that leads to lower pain score and decreased use of opioids and its related complications
The role of Helicobacter pylori eradication therapy in matrix metalloproteinase 9 inhibiting in gastric cancer
Get PDFIntroduction and Objective: Gastric cancer is the second common malignancy and is one of the major causes of cancer death. Helicobacter pylori infection is a risk factor for this cancer. The tissue damage caused by Helicobacter pylori in the stomach increases the level of MMP9, which by the proteolysis of many extracellular matrix compounds plays an important role in inducing cancer and metastasis. This study aimed to investigate the role of Helicobacter pylori eradication therapy in reducing MMP9 levels.
Materials and Methods: This interventional study was conducted on 60 patients with positive anti-Helicobacter pylori antibodies by ELISA method were selected in Ardabil city, Iran. After obtaining written consent, general information was collected from each patient using a validated and reliable questionnaire. The standard treatment for Helicobacter pylori eradication, including amoxicillin, clarithromycin, omeprazole and metronidazole, was prescribed. After 6 weeks, Helicobacter pylori eradication was confirmed by fecal antigens. 3 cc Fasting blood samples were taken from all of the patients for testing of MMP9 level at the beginning and end of the study. Then data were analyzed.
Results: Findings showed that 55 % of patients were female. The mean age of patients was 48±2 (mean ± SD) years. The serum level of MMP9 decreased signifi¬cantly in the patients (p<0.05).
Conclusion: Helicobacter pylori eradication therapy may inhibit gastric cancer induction by modulating serum MMP9 levels
Evaluation of anti leishmanial effect of Paraquat on Leishmania major promastigote by MTT assay
Get PDFBackground & objective: Leishmaniosis is a group of infectious diseases that are caused by various species of Leishmania, and its clinical manifestations include: cutaneous, mucocutaneous, visceral and diffused cutaneous leishmaniasis. The prevalence of disease is high, and 12 million people are involved by leishmaniasis, 350 million people are being threated around the world, and it is estimated that there are 2 million new cases, annually. Cutaneous leishmaniasis is common in Iran. The first-line drugs used for leishmaniasis treatment are pentavalent antimonials (Glucantime) which have multiple side effects such as drug toxicity. Moreover, parasite resistance to this drugs is rising around the world. Second-line drugs including Amphotricine B and Miltefosine have also side effects and expensive for patients. According to the cytotoxic effects of paraquat, this study was conducted to evaluate the anti leishmanial effect of paraquat, in comparison Glucantime on Leishmania major promastigotes by MTT assay.
Methods: Leishmania major was cultivated in BHI medium. A number of 2.5×106 promastigotes in BHI medium in stationary phase were added to each well of the 96 well culture plate. Paraquat was added at different concentrations (39, 58.6, 78.1, 117.2, 156.2, 234.3, 312.5, 468.7, 625, 937.5 and 1250 µg/ml). As a control group, Glucantime was used in different dilutions. The parasites were incubated for 48 hours in 24 ° C. The plate centrifuged for 10 minutes at 4 ° C and supernatant were discarded, 50 μl MTT was added into each well and, after three hours of incubation at 24 ° C, 100 μl of DMSO was added and OD was measured by a microplate ELISA reader (nm570). In addition, Trypan blue assay was performed to evaluate paraquat effect on Leishmania major promastigotes.
Results: MTT results showed that increasing concentrations of paraquqt could significantly reduce cell viability and number of Leishmania major promastigots compared to the control group (p<0.05). In concentrations of 468 µg/ml, all promastigotes were killed. In this study, the IC50 was 272/46 µg/ml. Trypan blue assay confirmed results of MTT assay.
Conclusion: Paraquat has strong inhibitory effect on Leishmania major promastigots. More expended studies are needed to evaluate its effect in “in vivo” conditions
The Effect of Zinc Gluconate in Treatment of Children Aged 2-23 Months with Acute Bronchiolitis Admitted to the Infectious Ward of Bo-Ali Hospital of Ardabil City in 2018
Get PDFBackground and objective: Acute viral bronchiolitis is the most common infection of the lower respiratory tract in infants under 2 years and is one of the reasons for their admission all around the world. The aim of this study was to investigate the effect of zinc gluconate in treatment of children aged 2-23 months with acute bronchiolitis admitted to the infectious ward of Bo-Ali hospital of Ardabil city in 2018.
Methods: Thid study was a randomized clinical trial in which 100 infants aged 2- 32 months with the diagnosis of bronchiolitis were included in the study considering inclusion and exclusion criteria. 50 patients received zinc gluconate and 50 patients received placebo. The symptoms and sign of the disease at baseline and then at 24, 72, and 7 days after starting treatment and duration of hospitalization were compared between the two groups.
Results: The treatment and placebo groups were similar in respect to mean age (5.82±4.13 vs 5.94±4.46, respectively, and P=0.889) and gender distribution (31 male vs 28 male, respectively, and P=0.542). There was no significant difference between the two groups in terms of clinical symptoms and signs at the time of admission. Bronchiolitis recovery was better in the treatment group than in the placebo group; This positive effect was statistically significant for vising (P = 0.023) and rhinorrhea (P = 0.027) 72 hours after starting treatment. Significantly, more patients in the treatment group were improved within 72 hours after starting treatment (74% vs 46% and P=0.004) and the mean duration of hospitalization was significantly less in the treatment group than in the placebo group (4.14±1.21 versus 4.64±1.2 days and P = 0.016).
Conclusion: The findings of this study showed that the use of zinc gluconate as a zinc supplement in infants aged 2 to 23 months with acute bronchiolitis admitted to hospital could improve clinical symptoms and signs and decrease the duration of hospitalization. However, given the limited studies in this area, further research is needed to provide appropriate recommendations for zinc use in the treatment of bronchiolitis in other populations
Aesthetic outcome of immediately restored single implants placed in extraction sockets and healed sites of the anterior maxilla
Get PDFIntroduction: Immediately restored single implants placed in extraction sockets and healed sites, is a newer method than other implant surgery methods. Considering this point is important that the use of this technique in the interior is a newer approach. According to this content, this study was designed and evaluated the aesthetic outcome of immediately restored single implants placed in extraction sockets and healed sites of the anterior maxilla.
Materials and Methods: In this case-series study, 18 patients were selected from two private clinics that needed to place an anterior single tooth implant including one canal to a maxillary canine. The maxillary premolar teeth were considered as candidates when they were in a beautiful area during a smile, to assess the status of aesthetics, the IBOI Pink & White Esthetic Score questionnaire was used; finally after collecting data, SPSS version 22 was analyzed by questionnaire and data entry.
Results: In general, the results of this study showed that the Status of mesial papilla, distal papilla, curve of the facial soft tissue, level of the facial peri-implant mucosa, root convexity soft tissue of the anterior maxilla of immediately restored single implants placed in extraction sockets and healed sites of the anterior maxilla At the optimal level (P <0.05); Also, the results showed that there was a significant difference in soft tissue aesthetics in 6 months and 12 months (P <0.05).
Conclusion: Considering the optimal position of implant placement and subsequent implantation in the anterior maxilla and its confirmation in this study and previous studies, it is recommended for dentists to use this metho
A novel antigen of Mycobacterium tuberculosis and MPLA adjuvant co-entrapped into PLGA:DDA hybrid nanoparticles stimulates mucosal and systemic immunity
No full textBackground
Due to initiation of Mycobacterium tuberculosis infection via the mucosal tissue of the respiratory tract, intranasal administration of new tuberculosis vaccines is highly regarded to enhance mucosal immunity. Our outline was evaluation of mucosal and systemic immune responses in BALB/c mice after nasal delivery of HspX/EsxS fused antigen of Mycobacterium tuberculosis along with MPLA adjuvant entrapped in PLGA:DDA hybrid nanoparticles.
Methods
In this study, the double emulsion solvent evaporation method (w/o/w) was used to prepare different nanoparticle formulations containing HspX/EsxS protein and MPLA. Three weeks after the last nasal immunization of BALB/c mice, IgA antibody levels in nasal lavage and IFN-γ, IL-4, IL-17 and TGF-β cytokines in supernatant of cultured splenocytes and also serum IgG1 and IgG2a titers were evaluated using ELISA method.
Results
Our results indicated that nasal vaccination with PLGA:DDA nanoparticles loaded with HspX/EsxS protein±MPLA, both with and without a prime dose of BCG could provide efficient Th1, Th17, IgA, IgG1 and IgG2a immune responses.
Conclusion
These findings demonstrate that both PLGA:DDA hybrid nanoparticles as carrier/adjuvant and MPLA as adjuvant, could efficiently induce mucosal and systemic immune responses against HspX/EsxS antigen, alone or as a booster for BC