Ardabil University of Medical Sciences
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Urinary screening for detection of renal abnormalities in asymptomatic pre-school children referred to Ardabil city health centers from 2016 to 2017
Background: Urinary screening for detection of proteinuria, hematuria, and pyuria for early diagnosis curable or preventable renal disease in three decade has been considered. The aim of this study was urinary screening for Detection of renal abnormalities in asymptomatic pre-school children referred to health center in Ardabil city from 2016 to 2017.
Methods: This was a cross-sectional descriptive study that has been done on urine specimens of 350 children who referred to Ardabil city health center to injection DTP vaccine from April 2016 to Sep 2017. In these infants, proteinuria, hematuria, pyuria and urinary casts were examined and abnormal finding were referred to future investigation to nephrologist. Information was collected and analyzed by statistical methods in SPSS version 21.
Results: A total of 350 children were enrolled in the study. There were 196 (56%) boys and 154 (44%) girls. The prevalence of urinary abnormalities in all children was 8.3%. Of all urinary abnormalities, proteinuria and hematuria were detected in 12 children (3.44 %). Of all infants, 9 children (2.57%) had pyuria. Also, 6 children (1.8%) had urinary casts that of them two cases had acid ureic cast and four cases had calcium oxalate cast.
Conclusions: This study showed that the prevalence of urinary abnormalities in Ardabil city children was similar to other studies in other country or cities. The reasons of this may be different in race and ethnic. We suggest that routine urinalysis should be part of screening of children at the school entry in Ardabil
The concern of today’s families: computer games for children and adolescents are Useful or harmful
Assessing quality of life of asthma patients over 12 years old under the supervision of Asthma and Allergy Clinic of Ardabil University of Medical Sciences
Background: Asthma is one of the most common chronic diseases that has a significant prevalence and incidence and in recent years due to the presence of various stressors has increased and despite advances in science, this disease is still a problem in the medical world. Reporting patient health status and assessing patients' quality of life increases clinical data, and integrating it with clinical practice can dramatically improve care outcomes. Therefore, quality of life assessment can be a useful tool for standardizing communication between physicians and patients that potentially improves clinical and functional outcomes.
Aim: To determine the quality of life criteria in asthmatic patients over 12 years old under the supervision of Asthma and Allergy Clinic.
Matherials and Methods: The statistical population was people over 12 years of age with asthma referred to the Asthma and Allergy Clinic of Ardabil University of Medical Sciences. The sampling method was counting or census and the sample size was proportional to the number of referrals and according to similar studies was 200 people. Data collection time was from July to August 2020 and the questionnaire used was SF36 Quality of Life Questionnaire.
Result: 200 patients were included in the study. The mean age of patients was 29.64 years. The highest age group was 15 to 25 years. 103 patients (51.5%) were male and 97 patients (48.5%) were female. Regarding patients' residences, the highest number of residences was related to Ardabil and the lowest number was related to Nir. Regarding the monthly income of patients, the average income of study participants was 3.47 million Tomans per month. The average cost of treatment among study participants was 230.10 thousand tomans. . 105 patients (52.5%) had an allergic type, 47 patients (23.5%) had a non-allergic type and 48 patients (24%) belonged to the samter phenotype. The control level of most patients was good. Statistical analysis showed that the majority of patients were in the fourth stage of treatment. And the economic burden of the disease is heavy in the eyes of the majority of patients. In our study, it was found that patients with allergic phenotype have a better quality of life than other patients, and also the better the level of asthma control, the better the quality of life of patients. Patients with treatment costs less than 250 thousand tomans have a better quality of life than patients with higher treatment costs. Also, patients under 25 have a better quality of life than patients over 35. It was found that the quality of life in steps 1, 2 and 3 is better than higher treatment steps. Gender and place of residence have no effect on patients' quality of life
Conclusion: Quality of life of asthmatic patients is related to asthma phenotype, asthma control status, average cost of treatment, and age and step therapy of the patient
Evaluation of clinical, laboratory and radiographic characteristics of Patients With Alkaptonuria ochronosis in Ardabil Province
Background: Alkaptonuria is a rare recessive autosomal metabolic disease that occurs due to a deficiency of the homogenetic acid oxidase hepatic enzyme. Symptoms usually appear as discoloration of the tissues and degenerative joint disease usually after 1 to 2 years of age.
Aim: evaluate the clinical manifestations and radiographic and laboratory findings of patients with Alkaptonuric Akronosis in Ardabil province.
Patient and methods: In this cross-sectional, descriptive-analytical study, all patients with Alkaptonuronic Acronosis in Ardabil province who referred to rheumatology clinic after obtaining informed consent were enrolled. A questionnaire including demographic information, height, weight, history of smoking and alcohol, educational level, occupation, clinical presentation, laboratory and radiographic findings were completed for each patient. The data were recorded in the relevant checklists and the results were statistically evaluated.
Results: In this study, 28 patients were eligible for inclusion, 7 of whom were in alkaline phase and the rest had clinical symptoms. The mean age of patients was 49.82 ± 17.2 years and mean age of onset was 42.13 ± 11.51 years. The mean age of patients with clinical symptoms was 57.10 ± 10.21 years and mean age of onset of clinical symptoms was 42.05 ± 11.43 years. The minimum age of onset of clinical symptoms was 20 and maximum 68 years.
The average duration of clinical symptoms to admission was 9/45 ± 6/60 years. Of the 27 patients studied, 12 were male and 16 were female. The most common symptoms in symptomatic patients were back pain and skin symptoms, cartilage involvement (pigmentation and discoloration of the ear), ocular symptoms, pelvic, nail and shoulder involvement respectively. In terms of radiographic findings in patients with clinical symptoms, the most common findings were wafer sign in thoracic and lumbar vertebrae, cervical spine and knee joint involvement, which was observed in 90% of patients.
Conclusion: Investigation of clinical manifestations and radiographic and laboratory findings of patients with Alkaptonuric Akronosis in Ardabil showed that back pain is the most common complaint in these patients and it is necessary to obtain more detailed history and examination in case of low back pain
Determining prevalence of C-shaped canals in mandibular first and second molars using CBCT
Introduction & Objective: C-shaped canal is formed when a fusion or adhesion occurs on the buccal or lingual side of a tooth between its mesial and distal roots. The aim of this study was to investigate the prevalence of C-shaped canals in the first and second mandibular molars using CBCT.
Materials and Methods: This research was a descriptive analytical cross-sectional study. The statistical population of this study consisted of all CBCT stereotypes of Dr. Baser and Rad Radiology Center in Ardabil, which are available in the archives of the mentioned centers from 2017 to 2019, which were selected using random sampling method and sample units. Evaluation of the C-shaped canal in the first and second molar of the mandible was performed based on the classification of Fan.
Results: Finally, 369 patients were studied, of which 199 (53.9%) were male and 170 (46.1%) were female. 36.3% had the highest frequency between 31-40 years and 3.5% had the lowest frequency over 60 years. Of the 182 people who had the first molar, 11 had a C-Shaped canal, all of which had the shape of a C2 canal. Of the 330 patients with second molars, 18 (20 teeth) were C-Shaped, with 4 out of every 4 types, with C2, C3, C1, and C4 being the most common with 9, 6, 3, and 2, respectively. The frequency of C-shaped canals was significantly higher in men and in the first molar (P <0.05).
Conclusion: The results of this study showed that more C-shaped canals were seen in the first molar than the second molar. Also, only C2 was seen in the first molar, but in the second molar there were all 4 types of canals. It was also observed that the frequency of C-shaped canals was significantly higher in men than in women
Frequency of deaths and physical disabilities caused by recorded accidents in student community in Ardabil between 2011 and 2017
Background: Student incidents are incidents that occur in the school environment. Student incidents can include incidents such as traffic accidents, falls, collisions, burns, electric shocks, and conflicts. However, due to the sensitivity of the matter, accurate statistics of student incidents in the city of Ardabil are not available, so examining the frequency of incidents that have caused death and handicap in the student community of Ardabil, can pave the way for providing solutions to reduce these incidents and handicaps and other complications related to incidents in this city.
Aim: To determine the frequency of deaths and physical handicaps caused by incidents registered in the student community of Ardabil between 2011 and 2017.
Materials and Methods: In this retrospective cross-sectional descriptive cross-sectional study, data related to the incidents of 7 to 18 year old students in Ardabil during the years 2011 to 2017 were collected from 750 students who had an incident. The collected data from Teacher Insurance and Fatemi Hospital in Ardabil were analyzed by SPSS25 software and chi-square tests and ANOVA analysis of variance
Results: The total number of incidents registered in the student community between 2011 and 2017 was 750 cases that 475 cases (63.33%) included quarrels and falls, 236 cases (31.47%) included accidents and 39 cases (5.2%) included burns. The mean age of the injured children was 13.04± 3.17. The rate of death and handicap caused by incidents included 22 cases (2.93%) deaths and 18 cases (2.4%) handicaps. Traffic accidents with 13 cases (59.0%) deaths and 6 cases (33.33%) handicap; Conflict and fall were associated with 8 cases (36.4%) death and 4 cases (22.22%) handicap and finally burns with 1 case (4.6%) death and 8 cases (44.44%) handicap . The mortality rate and handicap of children were not significantly related to their age; However, the incidence of accidents and burns increased with age (P <0.05).
Conclusion: According to the results, it seems that male students are more prone to accidents than female students. Involvement and conflict compared to other factors can play a role in the occurrence of accidents. Finally, traffic accidents can play the largest role in student death, but conflicts and falls, and burn incidents can play the largest role in student handicap
The situation of domestic violence in married women with addicted and non-addicted spouses in Urmia
Domestic violence The physical abuse perpetrated by a family member against another member or members, often perpetrated by men against women. Although violence against women is banned in many countries of the world and people are prevented from committing it, the reality is that violence against women is hidden behind rituals, cultural customs, social norms and beliefs. Addiction is one of the problems that not only endangers the lives of millions of people today, but also makes their families face many problems. In this descriptive and comparative study, 300 women were abused, 39 of whom had an addicted spouse.
Materials and Methods: The required information was collected using a questionnaire containing demographic characteristics by face-to-face interview. The questionnaire also contained information on physical, sexual, economic, and psychological-verbal violence.
Results: 39 women (13%) had an addicted husband. The rate of physical, sexual and economic violence in women who had addicted husbands was 92.3% (36 women), 79.5% (31 women) and 76.9% (30 women), respectively, and in women who did not have addicted husbands. They were 88.9 (232 women), 71.6% (187 women) and 88.9 (232 women), respectively. It was found that the difference between the overall mean scores of addicted and non-addicted spouses in violence experienced and also its sub-tests is significant. This study also showed that physical violence (P = 0.042) and economic violence (P = 0.036) against women with addicted husbands are significantly higher. However, there was no significant relationship between husband addiction and sexual violence (P = 0.35).
Discussion and Conclusion: Due to the high level of violence experienced in the spouses of addicted people, it is necessary to try to prevent addiction in married people, including accuracy in premarital tests and eliminating the causes of addiction, including poverty and unemployment. Other effective interventions for reducing addiction, including training and supportive and intervention counseling, are recommended
Assessment of soft and hard tissue around Single-implants based on gingival biotype in the posterior region of the mouth
Due to the growing acceptance of patients for the use of dental implants, today the use of dental implants to replace missing natural teeth is a standard treatment option with well-developed components. Achieving beauty in an implant depends on three factors: the proper position of the implant, the amount of bone on the buccal surface of the implant, and the condition of the soft tissue around the implant. Today's knowledge states that maintaining the health of soft tissue in the maintenance and long-term success of implants is as important as osteointegration and the presence of sufficient bone around the implant. Based on gingival biotypes.
Materials & Methods: In this study, 48 single-unit implants from a private office center, one year after implant placement, were selected for this study, and then the gingival biotype status was evaluated using the Transplant Probe Transplantation (TRAN) method. If the probe was seen from beyond the gums, the patient's biotype was considered Thin, and if the probe was not observed, the patient's gingival biotype was considered Thick. Then we divided the patients into two groups of patients with Thin gingival type and patients with Thick gingival biotype. After classifying the patients, the periodontal status around the posterior dental implants was evaluated for BOP, PPD, GI in each of the Thin and Thick gingival biotype groups, and then the extent of bone resorption around the implant (Bone Loss) using radiography. Parallel PA, we measured the rate of bone resorption from the implant platform to the site of the first implant-bone contact by using Remexis radiology software and We examined hard tissue, soft tissue and periodontal tissue of patients in both groups by using T-test and Chi-Square test.
Results: In terms of statistical comparison, the relationship between gingival biotype and bone loss (Bone Loss), BOP, PPD, GI was significant, while the relationship between gingival biotype and PI was not significant.
Conclusion:Hard tissue condition, soft tissue around implants with Thick biotype is better than Thin
The immune response and immune evasion characteristics in SARS-CoV, MERS-CoV, and SARS-CoV-2: Vaccine design strategies
The worldwide outbreak of SARS-CoV-2, severe acute respiratory syndrome coronavirus 2 as a novel human coronavirus, was the worrying news at the beginning of 2020. Since its emergence complicated more than 870,000 individuals and led to more than 43,000 deaths worldwide. Considering to the potential threat of a pandemic and transmission severity of it, there is an urgent need to evaluate and realize this new virus’s structure and behavior and the immunopathology of this disease to find potential therapeutic protocols and to design and develop effective vaccines. This disease is able to agitate the response of the immune system in the infected patients, so ARDS, as a common consequence of immunopathological events for infections with Middle East respiratory syndrome coronavirus (MERS-CoV), SARS-CoV, and SARS-CoV-2, could be the main reason for death. Here, we summarized the immune response and immune evasion characteristics in SARS-CoV, MERS-CoV, and SARS-CoV-2 and therapeutic and prophylactic strategies with a focus on vaccine development and its challenges