Ardabil University of Medical Sciences
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Redefining and comparing family structure in different theories
Get PDFIn the divine system, by addressing family authenticity in future manuscripts and explaining it in a space devoid of negative affectors, a long-term view of the family structure not only in the world but in the spaces ahead is one of the places to consider. By explaining the structure of the family in the best position in the Qur'an, God has made it clear in the Qur'an that the pattern of the family can be continued in various situations, including worldly life and the stages ahead. In this article, in addition to addressing family issues in order to continue and redefine the family structure in various theories, we will analyze this structure in the Qur'an
A comprehensive review of clinical studies with herbal medicine on polycystic ovary syndrome (PCOS)
No full textBackground
Polycystic ovary syndrome (PCOS) is a frequent medical condition characterized by both metabolic and reproductive disorders. Different pharmaceutical treatments have been proposed for PCOS. However, side effects of long-term treatments and their probable low efficacy have made complementary and alternative treatments a valuable option. Recent reports have indicated the increased use of complementary treatments. Herbal medicine, as part of complementary medicine, was find introduced in traditional Persian and Chinese medicine. Medicinal herbs have used for a long time in the treatment of gynecological and infertility problems of PCOS patients. In this study, we aimed to review herbal medicines used for PCOS worldwide.
Methods
PubMed, Embase, Cochrane, and Scopus databases were searched for clinical trials and Randomized Controlled Trials based on related keywords. Data were collected from 1990 to 2019.
Results
According to a multitude of studies, a wide spectrum of herbs can be used to improve various aspects of PCOS. Herbs such as Cinnamomum verum, Trigonella foenum-graecum L., and Vitex agnus-castus can impact on menstrual and ovulatory dysfunctions, obesity, insulin resistance, lipid-metabolism dysfunction, and androgen excess-related conditions.
Conclusion
Some plants as natural remedies may have beneficial effects on improving different aspects of PCOS; but further studies are needed to investigate their mechanisms and safety
Effect of Hydroalcoholic Extract of Truffle (Terfezia Boudieri) on Serum Level of Thyroid Hormones in Male Rats
Get PDFBackground and Aim Thyroid gland makes Thyroxine (T4) and Triiodothyronine (T3) hormones. These hormones
are really effective in regulating and control of basal metabolism. The purpose of this study was to
assess the effect of hydroalcoholic extract of Terfezia Boundary (TB) on the serum level of thyroid hormones.
Methods & Materials In this experimental study, 30 male Wistar rats (weighing 200±10 g) were selected and
divided into five groups of 6 including control, sham (received normal saline) and three experimental groups
received TB with 75, 150 and 300 mg/kg doses via intraperitoneal injection for 14 days. Samples from all
groups were collected at the end of the 14th day directly from the heart to evaluate thyroid hormone. The data
were statistically analyzed in SPSS V. 12.
Ethical Considerations This study was approved by the Research Ethics Committee of Ardabil University of
Medical Sciences (Code: IR.ARUMS.REC.1396.48).
Results The results of this study showed that the T3 and T4 levels in the experimental groups 2 (150 mg/kg)
and 3 (300 mg/kg) increased significantly compared to the control group (P<0.001 and P<0.01, respectively).
The Thyroid Stimulating Hormone (TSH) level in the experimental groups 1 (75 mg/kg), 2 (150 mg/kg) and 3
(300 mg/kg) decreased significantly compared to the control group (P<0.05, P<0.001, P<0.001, respectively).
Conclusion Hydroalcoholi
Hydatid Cyst with Multiple Organ Involvement in Northwest of Iran, Ardabil Province
Get PDFBackground & objectives: Hydatid cyst is a major hygiene problem in Iran. In 80% of cases, only one organ is involved. However, multiorgan involvement has also been rarely reported. But it seems, the prevalence of hydatid cyst with the involvement of more than one organ in Iran is more than other world. The aim of this study was to evaluate the patients with hydatid cyst multi organ involvement in Ardabil province in northwest of Iran.
Methods: In this retrospective study, 34 patients with hydatid cyst with involvement in more than one organ were included. For each patient, a pre-designed questionnaire including name, age, education level, occupation, place of residence, cyst location, clinical manifestations and serologic test results were completed. Patients, who had previously a history of treatment due to hydatid cyst, were excluded from the study.
Results: The mean age of patients was 36.41 years. 61.8% of the patients were housewives and 64% were rural residents. The most commonly involved organs was liver and simultaneous involvement of liver and lung was observed in 38.2% of patients and was more in women. The association of the right lung cyst with the liver cysts was greater than that of the left lung. Only in 43% of the patients, the serologic test was positive for hydatid cyst, and the relationship between serologic test and type of involvement was not significant.
Conclusion: Regarding the high incidence of hydatid cyst involvement in more than one location in our region, in all patients, especially women with liver hydatid cyst, other organs, especially the lungs, should be investigate
Pulmonary Alveolar Microlithiasis
Get PDFA 65-year-old male visited our clinic with complaints
of progressive shortness of breath on exertion that
persisted for the last 4 years and dry mouth. He had
no known pulmonary disease and was 20 pack-year
smoker. Physical exam was normal except for bilateral
wheeze and coarse crackles on auscultation. Laboratory
results were normal, and pulmonary function test
showed moderate restrictive lung disease. Chest X-ray
images showed diffuse alveolar nodular pattern (sandstorm)
(Fig. 1); chest computed tomography results
revaled diffuse bilateral calcification with septal thickening
and black pleural sign indicative of pulmonary
alveolar microlithiasis (PAM) (Fig. 2).
PAM is a rare hereditary diffuse lung disease characterized
by widespread sand-like intra-alveolar calcifications.
Its etiology is unknown; however, it has autosomal recessive
pattern. Dry cough, shortness of breath, and
nonspecific chest pain are common symptoms, but the
patients could remain asymptomatic for years. The only
definite treatment for PAM is lung transplantation (1, 2)
Seroepidemiological prevalence of HAV Antibody in Ardabil in 2018
No full textBackground and objective: Recently, the epidemiology of hepatitis A virus (HAV) infection has been changing due to lifestyle-related variations. To our knowledge, there are no published data about the seroepidemiology of this infection in Ardabil, by which decisions on the commissioning of a vaccination program could be made. This study aimed to assess the seroprevalence of HAV immunoglobulin G (IgG) antibody at the Ardabil northwest Iran
Methods: In this cross-sectional study, 700 serum samples from Subjects referred to Gastroenterology and Liver Disease Research Center in both urban and rural areas of Ardabil, during 2018 tested for HAV IgG antibody using enzyme-linked immunosorbent assay (ELISA). The data analyzed was using the Descriptive statistics methods, Pearson chi-square test, Independent T-test and Mann-Whitney U in SPSS version 24 used.
Results: It was found of the remaining 665 (50.08%), 333 were men and 332 (49.9%) were women. The mean age of the subjects was 34.40±19.74 Also, 401 (60.30%) were positive for HA virus, 259 (38.95%) were negative and 5 (0.75%) were visual. Also in the present study were analyzed with parametric analysis.
Conclusion: The results of our study showed that the prevalence of hepatitis A virus was higher in patients referred to Ardabil Research Digestive and Liver Center. We recommend that population of the province are vaccinated against HAV
Operating Room Safety Status Based on Patient Safety Friendly Hospitals Standards at Ardabil University Hospitals
No full textIntroduction Patient safety is an important global concern in all areas of health care services. The purpose of safety in the operating room is to provide the safety of the operating staff and the safety of the disease undergoing surgery. Considering the special importance of patient safety in the operating room, this study was conducted with the aim of Operating Room Safety Status Based on Patient Safety Friendly Hospital Standards at Ardabil University Hospitals.
Methods: This cross-sectional study was carried out with the participation of all 57 operating room personnel of three university hospitals in Ardabil in 1396. The data collection tool was a standard questionnaire of the WHO Patient Safety Friendly Hospital. Validity and reliability of this questionnaire has been confirmed in numerous studies. Data were statistically analyzed using the SPSS 18 software program.
Results: According to the Patient Safety Friendly Hospital Standards, IMAM KHOMEINI Hospital with a score mean %82, ALAVI with a score %84 and FATEMI with a score %77 were in good condition.
Conclusion: given the importance of the subject, although the safety conditions of the hospitals studied were good, it seems, it should be continually included in the managers' plans, trying to achieve higher levels of Patient Safety Friendly Hospital Standards
Investigating the Effects of Phenytoin, Phenobarbital, Topiramate, Carbamazepine and Sodium Valproate on the Neurotransmitter Speed in Treated Seizure Children
Get PDFAnticonvulsants such as phenytoin, phenobarbital, topiramate, carbamazepine and valproate due to their beneficial effects and economic benefits in compare to new drugs are used more but these drugs are not harmless and sometimes had dangerous, safe and reversible side effects. Reduction of the nervous conduction velocity (NCV) is the common side effect of these drugs and it is of clinically importance if it is severe especially in treated children. Therefore, it is necessary to evaluate and compare the effect of each drug on NCV. The aim of this study was to investigate the effects of antiepileptic drugs on NCV. In this quasi-experimental study, 125 children with seizure were randomly selected and divided into six equal size groups which received phenytoin, phenobarbital, topiramate, valproate, carbamazepine and one group as control which no received anti-epileptic drug. Sensory and motor neural conduction velocity were measured and recorded for all children in groups. Collected data were analyzed by statistical methods in SPSS version 19. All of anticonvulsants were reduced the NCV in children but among all drugs, phenobarbital and phenytoin had the least and most impact on the NCV. The changes in NCV were not related to the age and gender of children. Results showed that the anticonvulsants had similar impact on NCV in generally but future studies are recommended by considering the other effective variables on response to drug
FNDC5 expression in purkinje neurons of adult male rats with acute spinal cord injury following treatment with methylprednisolone
No full textSpinal cord injury (SCI) is a serious and complex medical condition that can happen to anyone. At present, therapy mainly focuses on rehabilitation and pharmacological treatment, such as methylprednisolone. Supra-spinal changes in certain structures, such as the cerebellum, that receive many afferents from the spinal cord might be one reason for unsuccessful therapeutic outcomes. Recently, the expression of FNDC5 was reported in cerebellar purkinje cells as a possible neuroprotective agent. In the present study, we considered the expression of FNDC5 in purkinje cells following SCI with and without MP administration in adult rats with SCI. Thirty-five adult male rats were used in this study. The animals were randomly allocated into five groups, including SCI, spinal cord injury with methylprednisolone treatment (SCI + MP), operation sham, control, and operation sham with MP. Induction of SCI was achieved by using special clips to compress the spinal cord at a determined level. After a certain interval time, the animals underwent study for FNDC5 expression, apoptosis by using immunohistochemistry, western blotting, and TUNEL and Nissl staining. Our results showed a significant decrease in the number of purkinje cells following SCI. Therapy with MP inhibits apoptosis in irFNDC5 purkinje cells and restores them. Expression of FNDC5 significantly increased in SCI and decreased following MP therapy. We also showed other cerebellar cells with FNDC5 immunoreactivity in the two other cerebellar layers that were previously reported. Since irisin is known as a plasma product of FNDC5, we think it might be a plasma marker following therapeutic efforts for SCI; however, it needs further research. In addition, it is possible that changes in FNDC5 expression in purkinje cells might be related to neurogenesis in the cerebellum with unknown mechanism