Ardabil University of Medical Sciences
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knowledge of dental specialists of Ardabil about civil liability in 2018 and for producing educational content in this regard
Full text linkIntroduction: One of the problems that dentists and physicians face in their profession is patients' complaints against them in the judiciary, so it is necessary that this segment of society be aware of the relevant occupational laws and legal principles governing medical issues. The purpose of this study The study of dentists' awareness of civil liability due to negligence in diagnosis and treatment and ultimately the production of educational content in this field.
Method: In the present study, which is an analytical cross-sectional study, the knowledge of 51 dentists in Ardabil about civil liability due to negligence in diagnosis and treatment was assessed by presenting a questionnaire. Knowledge in terms of age, gender, work experience, local university Education, faculty member and grievance history were reviewed and analyzed. In the final stage, by producing an electronic training file in the form of a compact disc, the concepts related to the subject of civil liability and the pillars of civil liability of dentists were explained by considering the results of the awareness survey and emphasizing the cases where there is less relative awareness.
Results: Using the obtained information and analysis, it was found that the average level of knowledge of all dentists about civil liability is 2.97. In this way, with increasing age, the level of awareness increases (p = 0.001) and with increasing work experience, the level of awareness increases (p = 0.001). Those who had a history of complaints had a higher level of awareness. (p = 0.001) and also the level of awareness of those who were faculty members was higher (p = 0.001) and gender and university of study had no significant effect on the level of awareness of civil liability (p> 0.05).
Conclusion: The level of knowledge of specialist dentists about civil liability due to negligence in diagnosis and treatment is moderate that there is a need to increase lagal knowledge in this group
Plantar Fasciitis Treatment; Efficacy of Extracorporeal Shock Wave Therapy
Full text linkEfficacy of extracorporeal shock wave therapy (ESWT) in the treatment of plantar fasciitis (PF) is under debate in spite of applying in treatment. We aimed to investigate the efficacy of extracorporeal shock wave therapy in decreasing plantar fasciitis heel pain. Methods: Eighty patients fulfilled the inclusion criteria; 77 agreed to participate the study. Patients randomly divided into 2 groups of treating with NSAID alone and NSAID+ESWT and assessed in to periods of 4 and 8 weeks with a focus on ESWT effectiveness. Results: Visual analog score decreased significantly after eight weeks of treatment with ESWT+NSAID in comparison with NSAID group alone. (p<0.05) Conclusion: ESWT reduced pain of PF in our study. So it could be used as treatment options
A case of hydatid cyst in biceps femoris
No full textIntroduction
Hydatid cysts primarily involve the liver and lung, but could be presented in any site of the body including the muscles which is very rare.
Presentation of case
We report a 50-year-old woman with hydatid cyst in biceps femoris presenting as growing painful mass. There was also a small cyst in the liver. The cyst was completely excised and patient was treated with albendazole 15 mg/kg daily before and after surgery. The patient was symptom free during the three months follow-up.
Discussion
Hydatid cyst should be considered as differential diagnosis of any growing mass or cyst in the body in the endemic areas
Evaluation of the causes and therapeutic results of traumatic upper limb amputation in patients referred to Fatemi Hospital in Ardabil in 2018-2019
Full text linkBackground: Injuries are one of the important health problems that are important to control and prevent in epidemiology and public health. Skeletal organs are an important part of the body. Although a defect or loss may not endanger a person's life, it has serious negative effects on his quality of life and can cause problems in his daily work, work and economy.
Aim: To determine the causes and treatment outcomes of traumatic upper limb amputation in patients referred to Fatemi Hospital in Ardabil
Matherials and Methods: The statistical population included all patients referred to Fatemi Hospital in Ardabil with traumatic amputations. The number of samples was 230. All admitted patients due to amputation were extracted from the hospital information system in a total number over a period of two years and each case was studied and entered into the data extraction sheet based on the objectives of the data study. Gradually, the data entered the computer and were analyzed.
Results: The result was that men are significantly more prone to accidents. Most accidents occur in the workplace and during working hours. Sensory disturbance and infection are significantly greater in stump repair. There was no significant difference in motor limitation and deformity. Generally, the complications were less in V-Y plasty method.
Conclusion: Our study preferred to the V-Y plasty method
Investigating the predictive components of the HBM model (health belief model) in performing protective behaviors against Quaid 19 in the patients with breast cancer in Ardabil 2020
Full text linkBackground &Objective: Coronavirus disease 2019, which is currently the most common human infectious disease with a high incidence and mortality rate in the world, has affected various aspects of each person's life. This study aims to investigate the predictability of HBM model components (Health Belief Model) in performing protective behaviors against Covid 19 in patients with breast cancer in Ardabil.
Materials and Methods: This descriptive-analytical study was performed on 92 patients with breast cancer who are part of the list of outpatients and hospitalized in Imam Khomeini Hospital in Ardabil and registered in Ardabil Cancer Registration Center since 1999. 98. Data collection was done with a questionnaire and data analysis was performed using SPSS 24 software.
Results :The mean age of the subjects was 48.34 ±10.082. to do so, the Mann-Whitney test showed significant correlation between the position of the people and the model components of the health belief model.using the variance analysis test to compare the mean of scores of the above variables, the breakdown of marital levels was determined, where scores of scores between the married levels of individuals studied were not statistically significant differences.There were no significant differences between average scores of research units in terms of spouses.The tests conducted by Kruskal-wallis test showed between the average scores of model components according to the treatment type received by patients with a significant correlation of perceived sensitivity (0.01 = p).the effectiveness of effective factors on increasing awareness is television (5 per cent) (6 per cent)and the least effect of advertising signs (4.5 %). Conducting the logistic regression on the effectiveness of model components in carrying protective behaviors showed that self - efficacy perceived self - efficacy is a predictor of behavior.
Conclusion :The results showed that the perceived value of perceived benefits, perceived benefits, self - efficacy, motivation for health and the use of protective methods to carry out protection and perceived sensitivity and perceived obstacles to the working group were superior to each other
Effectiveness of rectal displacement devices in managing prostate motion: a systematic review
No full textPurpose To determine whether rectal displacement devices (RDDs) have a prostate-stabilizing effect during prostate
external beam radiotherapy (EBRT).
Methods A systematic literature search using the PubMed database from January 1, 2000 to December 30th, 2019 was
conducted. The effect of RDDs on inter- and intra-fractional prostate displacements was extracted.
Results From 356 articles identified via the PubMed database and hand search, 21 articles were included in the systematic
review. There was no randomized study. Twelve studies evaluated the role of the endorectal balloon (ERB) in managing
prostate motion. Four studies reported the effect of hydrogel spacer on prostate motion. Four studies examined the effect
of the rectal retractor (RR) on intra-fractional prostate motion, and only one study assessed the impact of ProSpare
(Nottinghamshire, UK) in reducing prostate motion.
Conclusion Using an ERB significantly reduces intra-fractional prostate motion. This prostate-stabilizing effect of the
ERB can translate into reduced planning target volume (PTV) margins and additional rectal dose sparing. Even with an
ERB in place, inter-fractional prostate displacements are seen. As a consequence, ERB application does not obviate daily
verification; however, this is not a crucial topic because pretreatment imaging is always done nowadays. As compared with
ERB, the hydrogel spacer significantly reduces rectal dose and toxicity without influencing prostate immobilization. The
RR can increase prostate and rectal inter- and intra-fractional stability without a clear influence on the reduction of rectal
toxicity. Finally, it is unclear whether ProSpare is a suitable device reducing prostate motion. Further study will be required
to clarify whether the prostate-stabilizing effects of the ERB and RR can result in a safe reduction of PTV margins and
further sparing of organs at risks, especially the rectum
Studying the Relationship of Mental Health and Other Factors with Preference of Delivery Method in Women Referred to Qamar Bani Hashem Hospital, Khoy, Iran
No full textBackground: Childbirth is a fundamental physical and emotional struggle. This study is an attempt to investigate the psychological factors related to the first delivery, and its relationship with the preference of the type of subsequent deliveries in women. Materials and Methods: This is a descriptive-analytical study in which 380 pregnant mothers referred to Qamar Bani Hashem Hospital in Khoy, Iran, who were hospitalized for childbirth, were selected by simple random sampling. Participants were first asked about their preference for the next type of delivery. Afterwards, the Individual and Social Profile Questionnaire, the Edinburgh Depression Questionnaire, the overt and covert anxiety of Spielberger, and the Wake-Forest questionnaire in the interview method were completed. All data were analyzed using SPSS software version 22.0. Results: There was no significant statistical relationship between psychological variables and the preferred type of delivery. Age, spouse's education level, and income were among the predictors of preference for delivery. These factors had a statistically significant relationship with confidence in the physician in participating women. Apart from income, there was a statistically significant relationship between other social factors with preference of the type of delivery. There was also another significant relationship between complications during childbirth and postpartum with a preference for the type of the next delivery (P<0.05). Conclusion: Based on the results, there was a relationship between socio-individual factors and complications during and/or after childbirth with a preference for the next type of delivery in women. Further studies are needed
Challenges of managing diabetes in Iran: meta-synthesis of qualitative studies
No full textBackground: Although several diabetes management and control programmes are introduced in Iran, many patients do not achieve diabetes-related clinical goals as recommended. The aim of this study was to identify the qualitative evidence for the challenges regarding diabetes management. Methods: A systematic review of qualitative studies following PRISMA guidelines was undertaken. Scopus, PubMed, Science Direct, and Web of Knowledge were searched as well as Persian databases including Magiran, Irandoc and SID from inception to August 2019. The included Studies were either in English- or Persian-language qualitative studies reporting the perspectives of patients, their relatives, or healthcare service providers. Content of the findings were analysed and organized according to Chronic Care Model framework. Results: Twelve studies met the inclusion criteria. Six main themes were identified including holistic understanding of patients, leadership and governance difficulties, service delivery, workforce, financing, and information and research. Conclusion: Challenges regarding the management of diabetes in Iran is multifaceted. Reforming the health care system or developing complementary strategies is essential to improve suitable health care model for patients with chronic conditions such as diabetic patients
RIPK3–MLKL–mediated neutrophil death requires concurrent activation of fibroblast activation protein-a
No full textCytokine-primed neutrophils can undergo a non-apoptotic type of cell death using components of the necroptotic pathway, including receptor-interacting protein kinase-3 (RIPK3), mixed lineage kinase-like (MLKL) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. In this report, we provide evidence for a potential role of serine proteases in CD44-mediated necroptotic death of GM-CSF-primed human neutrophils. Specifically, we observed that several inhibitors known to block the enzymatic function of FAP-α were able to block CD44-mediated ROS production and cell death, but not FAS receptor – mediated apoptosis. To understand how FAP-α is involved in this non-apoptotic death pathway, we performed immunoblotting experiments in the presence and absence of inhibitors of RIPK3, MLKL, p38 mitogen-activated protein kinase (MAPK), phosphatidylinositol 3’-kinase (PI3K) and FAP-α. The results of these experiments suggested that FAP-α is active in parallel with RIPK3, MLKL and p38 MAPK activation, but proximal to PI3K and NADPH oxidase activation. Interestingly, neutrophils isolated from the joints of patients suffering from rheumatoid arthritis (RA) underwent a GM-CSF - independent necroptosis following CD44 ligation; this effect was also blocked by both FAP-α and MLKL inhibitors. Taken together, our evidence shows that the RIPK3 – MLKL pathway activates NADPH oxidase, but requires, in addition to p38 MAPK and PI3K, a serine protease activity, whereby FAP-α is the most likely candidate. Thus, FAP-α could be a potential drug target in neutrophilic inflammatory responses to avoid exaggerated non-apoptotic neutrophil death leading to tissue damage
The Neuroprotective Effect of Mesna on Cisplatin‑Induced Neurotoxicity: Behavioral, Electrophysiological, and Molecular Studies
No full textPeripheral neuropathy and cognitive impairments following cisplatin administration may interfere with the clinical usage of the drug. Mesna is a chemoprotective agent with anti-inflammatory and anti-oxidant effects. Our study aimed to investigate the protective effects of mesna against cisplatin-induced neurotoxicity. Neurotoxicity was induced by the administration of 2.5 mg/kg cisplatin twice a week for four consecutive weeks in male Wistar rats. The neuroprotective effect of mesna (150 mg/kg/day) was evaluated through behavioral, electrophysiological, and molecular studies. Cisplatin treatment caused passive avoidance memory impairment, increased anxiety-like behaviors, altered thermal sensitivity, and decreased muscle strength in a grip strength test. Our electrophysiological studies indicated that administration of cisplatin induced peripheral sensory neuropathy and decreased the amplitudes of the compound action potential of sensory nerves. Cisplatin administration increased MDA and 4-HNE levels and decreased anti-oxidant (SOD and GPx) enzymes. Proinflammatory cytokines (IL-1β and TNF-α) and metalloproteinase-2 and 9 (MMP-2/9) were increased by cisplatin treatment. Morphological alterations were observed in the dorsal root ganglion (DRG) of cisplatin-treated rats. Cognitive impairments, anxiety, muscle strength, and thermal sensitivity changes induced by cisplatin were improved with mesna treatment. The reduced conduction velocity in sensory nerves was recovered in the cisplatin + mesna group. Mesna partially alleviated redox imbalance, reduced the proinflammatory cytokines, and MMP-2/9 levels. Mesna administration also relieved the morphological changes in DRG of cisplatin-treated rats. In conclusion, our results revealed that mesna can alleviate cisplatin-induced central and peripheral nervous system toxicity. These results support the concept that chemotherapy-induced neuropathy can be partially inhibited via mesna