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Are You Flipping Out or Flipping In? The How’s, Why’s, and What’s of the Flipped Classroom Model
Get PDFThere is an intense movement today toward the flipped classroom model, with budgets, technology development, media hype, free and open educational resources, and advances in learning theories experimenting with the flipped classroom. Yet, there remains much debate, resistance and confusion. In fact, many educators are flipping out over all the changes and expectations. In this session, these issues will be addressed by reviewing some of the history leading to flipped classroom models of learning and documenting the benefits in terms of infrastructure, time, pedagogy, and learning. In addition, several examples of flipped classrooms will be provided along with a series of guidelines on use. Across this session, many of the how’s, why’s, and what’s of the flipped classroom will be discussed allowing instructors to envision their own flipped class-room possibilities. Instead of flipping out, they will be flipping in
Literary Activism and The Black Feminist Woman Writer: a Study of Alice Walker and Carolina Maria de Jesus
Get PDFIn this essay I examine the relationship between black feminism, writing, and the possible ways we might interpret black feminist women’s writing as activism. I also explore the cross-cultural development of black feminism in the U.S. as compared to Brazil. The varying works of black feminist women, whose writing often reflects the intersectional places of oppression black women (and women of color) routinely face, perhaps unintentionally, creates safe spaces for black women to identify, reaffirm, and feel supported. Black feminism calls for the equitable treatment of all persons and proffers itself as both ideology and practice. Therefore, the safe visibility of black feminist women writers across the globe, a guarantee that is not always certain for black women, especially those in developing countries, is a necessary feat to combat. Safe visibility advocates for harassment free recognition, due payment for all works and basic respect for writers who help contribute to black feminist thought. Within this essay, a brief discourse about the ability for black feminism to safeguard black feminist writers and their words is of the upmost importance to highlight. Writers such as Alice Walker and Carolina Maria de Jesus, whom are further discussed in this essay, demonstrate the range of black feminist women writers to explore social inequalities and the undeniable ways black feminism, the women, writings and works, help maintain a sisterhood of accountability. It is only because of black feminism that I know of Carolina Maria De Jesus. Through her words, may she be seen, heard and advocated for more ever present
Brazil: a Day-by-Day Slideshow
Get PDFA slideshow of daily locations and activities of the Women\u27s Equality and Empowerment study abroad group, traveling in Brazil. Locations include Porto Alegre, Gramado, and Santa Cruz
Sorbitol Protection Assay Provides Insight into Antifungal Mechanisms of Boron Compounds against Candida albicans and Candida Glabrata
No full textIn order to determine if loss of cell wall integrity contributes to boric acid toxicity towards wild type and drug resistant Candida organisms, yeast growth in osmoprotective-high-sorbitol medium was compared to growth determined by turbidity (A450) in sorbitol-free medium. Initially it was discovered that hyperosmolarity without added boron (sorbitol medium vs Sabouraud’s dextrose medium) reduced turbidity by an average of 42% for 27 yeast strains. The addition of 0.2% boric acid to this test resulted in sorbitol protection equal to an average 6.5-fold increase in turbidity in the presence of sorbitol. We also determined that organoboron compounds obtained from commercial nutritional supplement products also inhibited growth of Candida. Based on this finding we applied the sorbitol protection assay to 16 selected strains of Candida with the result that sorbitol protection was also seen with boron gluconate
Mitigation of stomach dehiscence risk during gastrostomy tube changes - a retrospective analysis of patient outcomes.
No full textINTRODUCTION: Stomach dehiscence from the abdominal wall is a serious and potentially life-threatening complication of gastrostomy tube changes. This retrospective study evaluates gastric aspiration as an inexpensive and safe alternative to endoscopic or radiographic confirmation.
METHODS: From August 1998 to June 2016, 682 patients (301 female, 381 male) underwent 1713 gastrostomy tube changes in the medical setting, with an average age of 7.59years and an average site age of 3.43years. The most common diagnoses were GERD (304), aspiration (168), and failure to thrive (143).
RESULTS: All newly inserted tubes were aspirated to visually inspect for gastric fluid. This procedure as a confirmatory test for intragastric placement was found to have a positive predictive value of 99.5% and negative predictive value of 77.8%, with a sensitivity of 99.8% and specificity of 63.6%. In cases with successful aspiration of gastric fluid, 75.5% of changes resulted in no complications, with intraperitoneal insertion or leak in only 0.48% of cases.
CONCLUSIONS: Positive gastric aspirate is a strong predictor of proper G-tube placement with high sensitivity, eliminating the requirement of specialized equipment and the cost associated with endoscopic or radiographic guidance, and has a comparable or superior risk profile.
LEVELS OF EVIDENCE: Study of diagnostic test level II
Effect of Cutaneous Local Axon Reflexes, Perfusion Pressure, and Ischemia on Exogenous Cholinergic-Induced Eccrine Sweating in Humans
No full textHuman skin blood flow (SkBF) and sweating increase similarly during increases in skin sympathetic nerve activity, implicating common control and regulation. Previous studies have blocked sweating without affecting SkBF, but few have altered SkBF without affecting sweating because standard methods such as introducing an α-adrenergic agonist decrease SkBF but also engage receptors on the eccrine sweat gland. Thus, this study was designed to utilize mechanical perturbations to decrease SkBF during intradermal perfusion of a cholinergic agonist. Three intradermal microdialysis fibers were placed in dorsal forearm skin of 1 woman and 3 men (age 24±1 years, BMI 23±3 kg/m2) to perfuse 2 doses of pilocarpine nitrate (0.01 and 1.66 mg/ml, corresponding to the ED50 and EMAX from previous dose-response modeling) or the vehicle (lactated Ringer’s). Forearm SkBF (laser-Doppler flowmetry) was decreased by engaging the venoarteriolar response (arm lowered ~30 cm from heart level; CVAR), venoarteriolar response plus a decrease in perfusion pressure (venous occlusion by proximal cuff inflation; CVAR with DPP), and ischemia (arterial occlusion by proximal cuff inflation) and sweat rate was measured by perfusing anhydrous medical air through a ventilated capsule (capacitance hygrometry). Decreased SkBF was observed with CVAR (58±10, 59±4, and 63±8%), CVAR with DPP (30±13, 22±14 and 37±3%), and ischemia (98±1, 100±2 and 91±3% for the pilocarpine ED50, pilocarpine EMAX, and vehicle control, respectively). Despite these significant decreases in SkBF, changes in eccrine sweat rate were minimal (CVAR = 5±5, 9±4, and 8±6%; CVAR with DPP = 6±8, 1±5, and 7±6%; and ischemia = 5±7, 5±4, and 6±5% for the pilocarpine ED50, pilocarpine EMAX, and vehicle control, respectively). These preliminary data suggest that acute decreases in SkBF do not proportionally decrease cholinergic-induced sweating in human forearm skin. One interpretation of this is independent control and regulation of cutaneous blood vessels and eccrine sweat glands in humans
Effect of Decreasing Peripheral Skin Blood Flow Via Local Axon Reflexes, Decreases in Perfusion Pressure, and Ischemia during Systemic Thermal-Induced Eccrine Sweating in Humans
No full textIn humans, skin blood flow (SkBF) and sweating are tightly coupled, suggesting common neural control and regulation. This study was designed to separate these two sympathetic nervous system end-organ responses via SkBF-decreasing mechanical perturbations in the presence of a strong sudomotor drive. Two women and 4 men (age 26±1 yrs and BMI 24±4 kg/m2) were tested in normothermia and heat stress conditions by pumping neutral (34°C) and hot (46-50°C) water through a high-density tube-lined suit to either maintain internal temperature (pill telemetry) or increase it by ~1.0°C. Arm and leg SkBF (laser-Doppler flowmetry) was decreased by engaging the venoarteriolar response (limb lowered ~30 cm from heart level; CVAR), venoarteriolar response plus a decrease in perfusion pressure (venous occlusion by proximal cuff inflation; CVAR with DPP), and ischemia (arterial occlusion by proximal cuff inflation). Decreased SkBF was observed with CVAR (30±7 and 60±15%), CVAR with DPP (44±12 and 86±11%), and ischemia (96±1 and 99±1% for the arm and leg, respectively) during normothermia. Despite these significant decreases in SkBF, there were no significant effects on transepidermal water loss (TEWL). Heat stress increased intestinal temperature from 37.1±0.1 to 38.0±0.1°C, heart rate (ECG) from 65±5 to 93±4 bpm, arm cutaneous vascular conductance (SkBF/Mean arterial pressure*100) 52±12 to 473±85 units, and forearm sweat rate (capacitance hygrometry) from 0.0 to 0.6±0.1 mg/ml/min. During heat stress, decreased SkBF was also observed during CVAR (20±7 and 17±6%), CVAR with DPP (39±9 and 52±13%), and ischemia (99±1 and 100±1% for the arm and leg, respectively). Despite these significant decreases in SkBF, eccrine sweat rate was not significantly affected. These data indicate that a wide range of acute changes in SkBF do not appear to affect TEWL or eccrine sweating in peripheral skin, indicating that there is independent neural control and regulation of these two sympathetically controlled end-organs
Msgr Raymond T. Bosler at the Second Vatican Council, 1962-1965, and After
Get PDFThis manuscript analyses the investigative efforts of Raymond T. Bosler in providing a journalistic analysis of all four sessions of the Second Vatican Council, as published in The Criterion.
William Doherty is Professor Emeritus within the Department of History and Social Sciences, teaching from the Fall of 1963 to December 2000
Using Heterologous COS-7 Cells to Identify Semaphorin-Signaling Components.
No full textSemaphorins are a family of membrane-bound and secreted type of proteins which were initially identified as chemorepulsive axon guidance molecules. Plexins and neuropilins are two major receptor families of semaphorins, and their common downstream targets are the actin cytoskeleton and cell-to-extracellular matrix adhesions. Semaphorins promote the collapse of growth cones by inducing rapid changes in the cytoskeleton and disassembly of focal adhesion structures. When transfected with appropriate receptors, non-neuronal COS-7 cells exhibit a similar cell collapse phenotype upon semaphorin stimulation. This heterologous system using COS-7 cells has been developed and widely used to investigate semaphorin-signaling pathways. In this chapter, we describe a COS-7 collapse assay protocol used to identify semaphorin-signaling components and a method to produce recombinant class 3 semaphorin proteins