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The cost of resetting discrete-time random walks
No full textThis submission contains 4 files (2 Julia programs, 1 Mathematica notebook and 1 .zip file) relevant to an upcoming publication, "The cost of resetting discrete-time random walks".
Julia Programs:
(i) Monte Carlo simulation to calculate the total cost distribution associated with resetting and jumps for a discrete-time random walker with stochastic resetting.
(ii) Numerical inverse Laplace transform algorithm based on "A Unified Framework for Numerically Inverting Laplace Transforms" by J. Abate and W. Whitt (INFORMS Journal on Computing, 2006). This is used to compare analytical results with Monte Carlo simulations.
Mathematica Notebook:
(i) The Mathematica notebook contains the derivation of the solution for the discrete-time random walker with a Laplace jump distribution and linear jump and resetting costs.
Simulation_data.zip file
(i) The .zip file includes simulation data, numerical inversion results, and a GNUplot script for visualization
Dataset for lift and trailing-edge deflection of passively morphing aerofoils
No full textThis dataset provides the results of the time-resolved force and trailing-edge deflection measurements for NACA0012 aerofoils undergoing periodic plunging motions. These experiments are conducted at the water channel facility at the University of Edinburgh. The aerofoil has a chord of c = 0.15 m and a span of 0.3 m. The flexible part of the aerofoil is made of glass-fibre composite, which has Young’s (tensile) modulus E = 1.86 GPa and density ρm = 2600 kg m^−3. The length of the flexible skin-section is 2/3 that of the chord. The trailing-edge surfaces have thickness b = 0.6 mm, giving a second moment of area of I = 5.4 × 10^−12 m^4. The reduced frequency is fixed at k = 0.2
Dataset for Impedance Spectroscopy of Hafnium Oxide: Memristive and Memcapacitive Switching with Annealing
No full textIn this study, we report binary resistive and capacitive switching in Hafnium oxide HfOx memristors. Given that annealed devices are widely recognised in the literature for exhibiting improved switching properties, we compared the behavior of as-deposited and annealed samples. Both devices exhibit pinched hysteresis with bipolar switching; however, annealed devices show significantly enhanced ON/OFF ratios for both resistive (1:100) and capacitive (1:3) states. The enhanced performance is attributed to post-deposition annealing at 400 °C, which induces monoclinic phase and hence results in a film that exhibits mixed amorphous and crystalline phase. To investigate the dynamic, frequency-dependent characteristics of these devices, we performed impedance spectroscopy analysis to get Bode and Nyquist plot. The Bode plot indicates that these devices function as tuneable low-pass filters, with as-deposited devices providing a bandwidth of 0.82 MHz and annealed devices exhibiting a significantly expanded bandwidth of 9.43 MHz. The Nyquist plots reveal the presence of a constant phase element (CPE) in both devices, with a stronger presence in annealed devices. The modeled parameters align well with experimental data within acceptable error margins. Additionally, LTspice simulations verify the model and the presence of non-ideal parameters. Our comprehensive study underscores the potential of HfOx memristors as reliable and tuneable memcapacitors, exhibiting improved performance for annealed devices
WeightGait Dataset
No full textHere we introduce the WeightGait dataset: a dataset developed for the purposes of facilitating vision-based gait assessment methodologies with more realistic conditions comparable to real world use. The motivation for this dataset is to create a testing environment for gait assessment algorithms that is closer to the realities of application. To accomplish this, unlike other similar datasets, we do two main things uniquely: We simulate overlapping abnormalities, for a total of 9 different combinations of abnormality detailed below. The background and equipment used are imperfect and noisy to simulate the similar hardship experienced when trying to install a gait monitor into someone's home. This means cheap recording equipment for scalability resulting in relatively low-frames per recording. It also means slight feet/head clipping at times, only a single camera view to detect depth and no curation to the background or the clothing/walking speed of the participants. The original 2D joint positions are estimated on the original videos using a lightweight implementation of the algorithm given in the paper 'HigherHRNet'
Comparative mutant analyses reveal a novel mechanism of ARF regulation in land plants
No full textAdditional data associated with the publication "Comparative mutant analyses reveal a novel mechanism of ARF regulation in land plants" Nature Plants, 2025.
Abstract:
The plant hormone auxin regulates a wide variety of transcriptional responses depending on the cell type, environment, and species. How this diversity is achieved may be related to the specific complement of auxin signalling components in each cell. The levels of activators (class-A AUXIN RESPONSE FACTORS) and repressors (class-B ARFs) are particularly important. Tight regulation of ARF protein levels is likely key in determining this balance. Through comparative analysis of novel, dominant mutants in maize and the moss Physcomitrium patens, we have discovered a ~500-million-year-old mechanism of class-B ARF protein level regulation mediated by proteasome degradation, important in determining cell fate decisions across land plants. Thus, our results add a key piece to the puzzle of how auxin regulates plant development.
These datasets are in addition to those included in the supplmentary materials in the paper, the raw sequence data provided in the NCBI GEO deposit, and the github pages (https://github.com/ThePlantShapeLab/Truffula )
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The raw sequence data associated with the project is available to download at GEO accession numbers GSE293375, GSE293431, GSE293432Please see README_Comparative mutant analyses reveal a novel mechanism of ARF regulation in land plants.txt file for information on each datase
Effect of deliberate physical damage and repair on the icephobicity of oil-infused elastomer coatings
No full textOil-infused elastomers have shown promise as anti-icing coatings, but their softness has led to durability concerns. The effect of damage is investigated to study the resilience of the icephobicity of silicone elastomer coatings with and without oil-infusion. Physical damage is applied to specimens by abrading with grit paper or cutting with a scalpel. Surface characterization reveals morphological changes in the coatings due to damage and de-icing on the surfaces, along with changes in the static water contact angle. Abrasion of the surfaces does not overwhelmingly or universally worsen the ice adhesion strength. Some damage even lowers the ice adhesion strength, possibly due to Cassie-Baxter wetting. However, it decreases the average freezing time. Cutting causes accelerated deterioration to ice adhesion strength and worsens freezing time. Though damage to the oil-infused coatings is greater, changes in icephobicity are similar to coatings without oil-infusion. Re-coating is an effective method of repairing even severely damaged surfaces and recovering icephobicity. We show oil-infused elastomers have durable icephobicity and are effective anti-icing coatings
Metagenomic analysis of dietary fiber-induced modulations in the caecal microbiota of chickens (ANI 99% MAGs: ENA project PRJEB77488)
No full textDietary fibers offer a potential solution to rising feed costs and feed–food competition. They are known to impact the health of birds by shaping their gut microbiota. Understanding of how dietary Fibers (soluble and insoluble) modulate caecal microbiota can help in devising targeted manipulation strategies to improve Fiber fermentation and ultimately enhance chicken productivity. Birds were divided into five different dietary groups (1) basal diet (CG): corn/soya-based diet; (2) GA: basal diet + 1% inulin; (3) GB: basal diet + 4% inulin; (4) GC: basal diet + 1% ARBOCEL; (5) GD: basal diet + 4% ARBOCEL. DNA from caecal contents was isolated, and shotgun metagenomic sequencing was performed. Raw sequencing files, primary assemblies, bins, and metagenome assembled genomes (MAGs) that were dereplicated at the species level (95% ANI) have been uploaded to the European Nucleotide Archive (project PRJEB77488). This dataset contains all MAGs produced from this project, dereplicated at the strain level (99% ANI)
Cardiovascular profile of Cushing Syndrome in mice
No full textCushing Syndrome, reflecting endogenous overproduction of ACTH or exogenous exposure to glucocorticoid medication, increases cardiovascular risk. Hypertension is a major factor but underlying mechanisms are not clearly defined. We modelled Cushing Syndrome in male C57BL/6J mice with prolonged ACTH infusion and measured blood pressure on control diet and following high salt intake. In a separate group we assessed renal function and salt excretion, the in vivo pressure natriuresis response and ex vivo artery function. We found that ACTH infusion impairs sodium excretion and causes a transition to non-dipping and salt-sensitive BP. Renal hemodynamic and tubular abnormalities impair the pressure natriuresis response. Our findings provide a landscape of the complex physiological response to ACTH excess that may contribute to poor cardiovascular health in Cushing Syndrome
The Stab Resistance of Bombyx Mori Silk Cocoons (Data)
No full textData related to the paper "The Stab Resistance of Bombyx Mori Silk Cocoons", the abstract for which follows: This study considers the mechanical response of Bombyx mori silk cocoons to knife stabbing, a simple but controlled way of simulating predaceous penetration. Here, we stab test both entire cocoons (EC) and cocoon wall segments (CWS) statically and dynamically, and note that the process can be broken down in three stages. The first stage involves material deflection, the second is knife penetration, and the third is knife perforation. It is found that ca. 95 % of the kinetic energy is lost during the penetration stage. There are noticeable differences in strain between the equatorial (
= 13 %) and meridional (
= 1.5 %) directions before and after the stabbing of EC specimens (p <0.001). The apparent area of the cocoon is noted to be on average 7 % lower after stabbing than it is prior to being stabbed (p <0.01). It is found that while compression of the cocoon from stabbing results in equatorial expansion (with a Poisson's ratio, ν = 0.25), in the meridional direction the cocoon contracts (ν = -0.05) thus displaying auxetic behavior. Force-deflection curves are different in CWS specimens as compared to EC specimens, and this is attributable to natural curvatures in CWS specimens remaining even after a being flattened for mounting and testing. Differences between EC and CWS specimens are also noticeable in the sizes of the stab footprints, with EC samples exhibiting 33 % smaller footprints than CWS samples (p < 0.001). It is concluded that testing whole cocoon structures provides a more accurate understanding of their properties as compared to cut and flattened structures. This is because flattening cocoon wall specimens induces delamination and multiple failure zones, reducing the natural stab resistance of the material.Excel file containing stress-strain data from tensile testing of the Bombyx mori cocoon wall:
Stress-strain data.xls
Excel file containing raw data for the dimensional changes in Bombyx mori cocoons along with their standard deviations and changes in normalised area of full cocoons:
Dimensional changes.xls
Excel file containing data for the stab force comparison of Bombyx mori cocoon wall and the entire cocoon:
Stab force comparison.xls
Excel file containing continuous force-displacement data from the Instron testing, presenting a comparison of the Bombyx mori cocoon wall and the entire cocoon:
Stab force against displacement.xls
Excel file containing data for the comparison of knife stab footprint for the static and dynamic testing:
Stab footprint area EC vs CWS.xl
CLAW: a Phase Differentiation and Biomechanical Modeling Software for Animal Claws
Full text linkCLAW is a software that provides an integrated platform for the high-resolution phase differentiation (material differentiation), and biomechanical modeling of animal claws. The workflow begins by converting two-dimensional (2D) DICOM slices from computer tomography (CT) scans into a three-dimensional (3D) volumetric model. From this 3D volume, users can perform segmentation to differentiate between regions of alpha-keratin, beta-keratin, and bone. Based on the segmented volume, the software enables the creation of single-material and composite-material meshes using 3D Delaunay tetrahedralization, based on machine learning to generate accurate surface, voxel, and volumetric meshes. After meshing, users can assign material properties (currently limited to a single material) to the whole claw, and perform finite element–based stress analysis under different loading conditions. The workflow ensures high geometric fidelity and supports the reproducible modeling of complex biological structures