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Hong Kong April 2024 - images of new estates
No full text### DOCOMOMO INTERNATIONAL MASS HOUSING ARCHIVE ### The provision of healthy modern housing for all was one of the foremost ideals of the Modern Movement, and inspired a vast wave of planning and building across the world during the 20th century. In the last quarter of the century, even as the foundational programmes of Europe and America lost their impetus, the baton was passed on to other countries, especially in eastern Asia, where the narrative of Modern mass housing was reinvigorated for the next century - a unique example of a key Modernist project that actually continues and thrives today, and which thus forms a principal focus of interest for DOCOMOMO – the leading international organisation promoting the documentation and conservation of buildings, sites and neighbourhoods of the Modern Movement. As heritage, the built legacies of this diverse and multi-generational adventure are almost always too controversial to qualify for conservation strategies. Instead, therefore, recording and inventorisation must dominate the heritage interest in this field. In the recognition of that fact, DOCOMOMO’s International Specialist Committee on Urbanism and Landscape, in partnership with the Scottish Centre for Conservation Studies at the University of Edinburgh, has launched the International Mass Housing Archive, whose aim is to provide an open-access library of images of significant housing projects in each working-group territory, free of copyright restrictions. These files may be copied, edited and shared on condition the appropriate citation is used, as per the terms of the attached Creative Commons Attribution licence. ### Structure ### The International Mass Housing Archive is subdivided under geographical headings corresponding to the constituent working groups of DOCOMOMO, and the individual housing projects are searchable under city and project name. Initially, the Image Archive will be managed and augmented centrally by DOCOMOMO and the SCCS, in partnership with University of Edinburgh Information Services, commencing with pilot city surveys sourced from our own photographic records in the first instance. The archive is related to several existing mass housing documentation initiatives. These include one concerning Britain, namely the online version of the 1994 book, Tower Block: http://towerblock.org/TowerBlock.pd
Cryptic dataset
No full textThe Cryptic dataset is constructed using from A Dataset of Cryptic Crossword Clues by George Ho (available at https://cryptics.georgeho.org)
This database consists of cryptic clues from multiple different sources, incuding the New York Times, The Guardian, The Times and The Hindu.
Each row in the database stores the clue (normally a cryptic sentence or two along with the length of the answer), the answer (normally a word or two), the definition (one or a few words, almost always either the start of the clue or the end).
We have extracted each clue that consists of 6 words from the database, and encoded the words with the BERT encoder to 6 word embeddings of dimension 768.
The task is to determine whether the cryptic clue contains the definition at the beginning or end of the clue. This makes a binary classification problem. The labels are as follows {beginning: 1, end: 0}.
The shape of the input data is (n, 1, 6, 768), and the labels are binary (0 or 1).
The extracted data is split into three sets, the test set consists of clues from The Times, the validation set from The Hindu, and the train set from all other sources
Pilot crossflow absorber hydrodynamic and mass transfer data
No full textThis data was generated during a comprehensive set of experimental runs of a pilot-scale crossflow absorber. The absorber is described in the PhD thesis titled "Crossflow absorber characterisation for the direct air capture of carbon" completed by MennatAllah Labib. The data includes hydrodynamic and effective mass transfer area measurements for six Mellapak 250Y.PP structured packings of slightly different geometries
Decolonised Transformations
No full textThis work is being conducted within the context of the UN International Decade for People of
African Descent (2015-24) and in the wake of calls by grassroots communities of reparatory justice interest, students-led
organizations and scholar-activists for higher education institutions (HEIs) to begin repairing the harms caused by
institutional ties to the enslavement of African peoples and colonial oppression, and their legacies today. Each HEI is
taking a different approach to their reparative justice programmes. Edinburgh is therefore at a critical point, and in a
unique position, to do something different. Restoring the dignity of racially minoritized peoples from multiple Black
(including African, African-descended, Caribbean) and Asian communities and other First Nation peoples requires an
action plan designed to both recognize the past while providing a vision for institutional and cultural development in the
future. The dataset comprises raw and anonymised responses from two questionnaires, cleaned and anonymised data,
data analyses and results, the documents used to obtain ethical approval for the questionnaires, and files used to recruit
participants for the questionnaires
Blood-based epigenome-wide association study and prediction of alcohol consumption
No full textThis dataset corresponds to the study “Blood-based epigenome-wide association study and prediction of alcohol consumption”. Files within this dataset include summary statistics for two Epigenome-wide association studies (EWASs) of alcohol consumption in Generation Scotland. One EWAS was conducted on only participants who's answer to alcohol consumption questionnaire reflected their normal drinking pattern. The other EWAS was performed on all participants with data available.
Abstract:
Alcohol consumption is an important risk factor for multiple diseases. It is typically assessed via self-report, which is open to measurement error through recall bias. Instead, molecular data such as blood-based DNA methylation (DNAm) could be used to derive a more objective measure of alcohol consumption by incorporating information from cytosine-phosphate-guanine (CpG) sites known to be linked to the trait. Here, we explore the epigenetic architecture of self-reported weekly units of alcohol consumption in the Generation Scotland study. We first create a blood-based epigenetic score (EpiScore) of alcohol consumption using elastic net penalised linear regression. We explore the effect of pre-filtering for CpG features ahead of elastic net, as well as differential patterns by sex and by units consumed in the last week relative to an average week. The final EpiScore was trained on 16,717 individuals and tested in four external cohorts: the Lothian Birth Cohorts (LBC) of 1921 and 1936, the Sister Study, and the Avon Longitudinal Study of Parents and Children (total N across studies > 10,000). The maximum Pearson correlation between the EpiScore and self-reported alcohol consumption within cohort ranged from 0.41 to 0.53. In LBC1936, higher EpiScore levels had significant associations with poorer global brain imaging metrics, whereas self-reported alcohol consumption did not. Finally, we identified two novel CpG loci via a Bayesian penalized regression epigenome-wide association study (EWAS) of alcohol consumption. Together, these findings show how DNAm can objectively characterize patterns of alcohol consumption that associate with brain health, unlike self-reported estimates
Creative Music Practice PhD - "Framing Freedom : Bandleading in Jazz and Improvised Music"
No full textThese are the non-commercially available audio and video recordings of the band Anthropods, which were used as part of the thesis "Framing Freedom : Bandleading in Jazz and Improvised Music". The thesis uses the concept of group language to examine the bandleader's role in creating the sound world of an ensemble in jazz and improvised music. As part of the thesis submission, a body of creative musical practice was generated systematically through the author's own practice-led enquiry on the development of group language within Anthropods.
Rehearsal and concert audio and video recordings from Anthropods. This is a collection of unreleased material from the band Anthropods(Susanna Gartmayer - bass clarinet, Irene Kepl - violin, Jakob Gnigler - tenor sax, Clemens Sainitzer - cello, Mark Holub drums/bandleader/composer).The files feature one rehearsal audio recording and two video recordings of concerts at the Porgy & Bess in Vienna, Austria.Forest Capers 20.10.2020.wav - Anthropods rehearsal recording of Forest Capers by Mark Holub, recorded on October 20th, 2020
and played by Anthropods.
Messy to Me - Forest Capers 2.2.2021.mp4 - Anthropods concert recording of Messy to Me and Forest Capers by Mark Holub and played by Anthropods at Porgy & Bess, Vienna, Austria February 2nd, 2021
For Charles - Pumpkin Patch 2.2.2022.mp4 - Anthropods concert recording of For Charles and Pumpkin Patch by Mark Holub on February 2nd 2022 at Porgy & Bess, Vienna, Austri
MND model gene dose proteomics
No full textData Generation: Tandem-mass-tagged mass-spectrometry (TMT-MS/MS) analyses of hippocampal synaptosomes of the Taiwanese mouse model of SMA, generated from n=5 each wildtype (Smn+/+), heterozygous (Smn+/-; SMN2tg/0) and homozygous (Smn-/-; SMN2tg/0) animals, respectively, yielded 6660 raw protein identifications derived from peptide sequences searched against Mus musculus UniProtKB/Swiss-Prot sequences using the MASCOT Search Engine (V2.3.2) through Proteome DiscovererTM software (Version 1.4, Thermo Fisher). Filtering to eliminate protein sequences identified by fewer than 2 or more unique peptides produced 6195 identifications ready for subsequent analysis.
TMT-MS/MS analyses of hippocampal synaptosomes against a novel rat model of ALS 8, generated from n=5 each wildtype (VAPB+/+), heterozygous (VAPB P56S/+) and homozygous (VAPB P56S/P56S), respectively, yielded 7828 raw protein identifications derived from peptide sequences searched against Rattus norvegicus UniProtKB/Swiss-Prot sequences using the MASCOT Search Engine (V2.3.2) through Proteome DiscovererTM software (Version 1.4, Thermo Fisher). Filtering to eliminate protein sequences identified by fewer than 2 or more unique peptides produced 5942 identifications ready for subsequent analysis.
Generation of ratios comparing heterozygous and homozygous expression compared to wildtype of filtered proteins enabled normalised measurement of expression alterations for subsequent analyses. Expression of each protein at wildtype is therefore equivalent to 1 (ie. wildtype: wildtype), while values >1 at heterozygote or homozygote indicate a relative increase in expression, and values <1 indicate a relative decrease in expression.
Application of Markov Clustering algorithm set to a Pearson correlation coefficient of 0.98 to each >2 peptide dataset, inputted as an identifier column of UniProt/Swiss-Prot Accession Number and expression ratio values at wildtype, heterozygous and homozygous in each condition produced discrete clusters based on the sole parameter of similarity in expression profile alteration through genotype. Isolated clusters correlating with levels of full-length Smn expression (SMA model) or mutant VapbP56S expression (ALS 8 model), constituting n=3802 proteins in SMA model and n=3168 in ALS 8 model were mapped to human gene identities in the Ingenuity Knowledge Database (Qiagen).
Ethics: Animals and tissue harvesting
All animals used in this project were treated in accordance with the guidelines outlined by the UK Animal Scientific Procedures Act (1986), adhering to the three principles of Reduction, Refinement and Replacement.
Description of data files:
-Supplementary Table 1_Analysis-Ready_Mapped Clusters_SMA
-Supplementary Table 2_Analysis-Ready_Mapped Clusters_VAPB
Datasets (each in two formats_.xls & .xlsx) contain all biologically relevant alterations identified through expression cluster analysis. 1 for each condition. Alteration of protein expression by >20% in homozygote synapse compared to through colourisation in green (decrease relative to wildtype) or red (increase relative to wildtype). Intensity of colour corresponds to magnitude of change.-Supplementary Table 1_Analysis-Ready_Mapped Clusters_SMA
-Supplementary Table 2_Analysis-Ready_Mapped Clusters_VAPB
Datasets (each in two formats_.xls & .xlsx) contain all biologically relevant alterations identified through expression cluster analysis. 1 for each condition. Alteration of protein expression by >20% in homozygote synapse compared to through colourisation in green (decrease relative to wildtype) or red (increase relative to wildtype). Intensity of colour corresponds to magnitude of change
Attachment-related anxiety and social anxiety: the mediating role of self-esteem
No full textThe dataset includes a unique reference number for each participant. It includes participants' responses to a 'consent to participate' question. It includes participant data, namely: gender, age group, relationship status, and ethnicity.
Participants responded to a shortened version of the Anxiety Subscale of the Experiences in Close Relationships Revised Scale (ECR-R). Reponses to the items of this questionnaire are listed under AA_1 : AA_9. The nine items chosen were those that load most strongly on the Anxiety subscale (see Sibley, Fischer & Liu, 2005).
Participants also responded to the Social Interaction Anxiety Scale. Responses to the items of this questionnaire are listed under SA_1 : SA_20.
Participants also responded to the Rosenberg Self-Esteem Scale. Responses to the items of this questionnaire are listed under SEst_1 : SEst_10
Thin Film Composite Mixed-Matrix Membranes based on Matrimid and Zeolitic Imidazolate Frameworks for CO2/N2 separation performance
No full textMembrane-based gas separation processes are a technology in continuous evolution. Various types of polymer membranes have been developed, many exhibiting high CO2 permeability and selective properties over competing gases such as N2 and CH4. In order to be competitive, membranes must be cheaper, more stable, more efficient and their production must be scalable. One solution is to develop thin film composites with mixed matrix membranes (TFC_MMM) that have the potential to boost productivity while maintaining low costs. In this work, TFC_MMMs containing Matrimid(r) mixed with 12%wt of ZIF-94 were prepared by kiss coating on a porous support. The SEM analysis showed that defect-free membranes with a 3 mm selective layer have been obtained. At 1 bar, the addition of ZIF resulted in the improved the separation performance for the CO2/N2 pair, with CO2 permeance of 4 GPU and CO2/N2 selectivity of 40, surpassing neat TFC-Matrimid (CO2 permeance~3 GPU, CO2/N2 selectivity~29). The use of ZIF-94 also had a stabilising effect on the membranes against CO2 plasticisation at high pressure
BioAsteroid_metabolomics
No full textMetabolomics analysis of the liquid fractions of samples from the BioAsteroid experiment, performed onboard the International Space Station between 2020 and 2021. It includes both ground and space samples