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Short range intervortex force coefficients
No full textWe present the coefficients for the short range expansion of the static vortex interaction from Ginzburg-Landau or Abelian Higgs model. The corresponding expansion of the vortex energy is given in the paper "Short range intervortex forces" by Martin Speight and Thomas Winyard. The columns include the required c's from section 5 to be able to model 2 and 3-body interactions as well as the coefficients q and m for the long-range interaction calculated in section V of Speight, J. M. (1997). Static intervortex forces. Physical Review D, 55(6), 3830
Emergence of signalling - simulation data
No full textThis dataset comprises sample output from simulation codes available at https://git.ecdf.ed.ac.uk/rblythe3/emergence-of-signalling for reproducibility of the results presented in the paper “Exploiting individual differences to bootstrap communication”. The simulation model involves a set of agents who use signals probabilistically to express meanings that are present in the environment, and show over time how a common communication system can emerge in the system, even in the absence of explicit feedback on whether interactions were successful or not.File naming convention and format is outlined in Readme.txt
Full details of how these files were generated and file formats can be found in the git repositor
Berlin (West)
No full textBerlin in the 1980s was in a state of suspension, with the physical trappings of the Cold War still omnipresent but subtly in decay. This collection of images, mostly dating from 1982, gives a vivid snapshot of the city’s multi-liminal character in those years, focusing mainly on the everyday trappings of division, including not only well-known setpieces of ‘The Wall’, such as Potsdamer Platz or Bernauer Strasse, but also lesser-known quirks such as border-straddling transport infrastructure (such as the extraordinary Wollankstrasse S-Bahn station, accessible only through a ‘hole in the wall’, as well as the better-known Friedrichstrasse) or anomalies such as the Steinstücken ‘exclave’. More generally, the S-Bahn network within West Berlin, latterly a quasi-extra-territorial DDR operation widely boycotted by West Berliners, is documented in its final state of truncation and rampant decay, seen most spectacularly in the images of the wildly overgrown Gesundbrunnen station – together with an early 21st-century image (from exactly the same viewpoint) of the latter’s rebuilt state as a bustling, modern national transportation hub. These historic photographs, which are made available in partnership with DOCOMOMO-International - the global network for documentation and conservation of the modern movement - are available as an open-access library of images, free of copyright restrictions. These files, which are divided into West Berlin and East Berlin sites, may be copied, edited and shared on condition that the appropriate citation is used, as per the terms of the attached Creative Commons Attribution licence
Data supporting the manuscript "A dynamical process-based model for quantifying global agricultural ammonia emissions – AMmonia–CLIMate v1.0 (AMCLIM v1.0) – Part 2: livestock farming"
No full textAgricultural ammonia (NH3) emissions are a major pathway of nitrogen loss, which can have significant environmental consequences, such as air and water pollution, ecosystem damage and biodiversity loss. Ammonia emissions related to livestock farming are major sources in the agricultural sector, resulting from animal housing, manure management and land application. This paper is the second part of the description of the AMmonia–CLIMate (AMCLIM) model, presenting the development and application of all three main modules to estimate NH3 emissions from livestock, including pigs, poultry (chicken), cattle, sheep and goats. The AMCLIM model simulates the flows of N species at different stages comprised in livestock agriculture. It incorporates the effects of environmental factors and also provides an adequate level of detail for the representations of human management practices. According to simulations by AMCLIM, it is estimated that NH3 emissions from global livestock farming are about 29.9 Tg N yr-1, accounting for around 30 % of total excreted nitrogen. Cattle and buffaloes systems are estimated to be the largest sources of NH3 emissions, contributing over 60 % of total livestock emissions. Both pigs and poultry systems result in more than 15 % of estimated total emissions, while sheep and goats are responsible for the remaining 7 %. High volatilization rates frequently occur in hot regions, indicating the climate-dependence of NH3 volatilization. It is also shown how AMCLIM can simulate the influence of management practices on NH3 volatilization, e.g., illustrating how fully-enclosed animal houses with heating and forced ventilation can result in higher emissions than naturally ventilated barns, while poorly managed manure leads to much more NH3 emissions
Rules of engagement for condensins and cohesins guide mitotic chromosome formation
No full textData from "Rules of engagement for condensins and cohesins guide mitotic chromosome formation". Kumiko Samejima, Johan H. Gibcus, Sameer Abraham, Fernanda Cisneros-Soberanis, Itaru Samejima, Alison J. Beckett, Nina Pučeková, Maria Alba Abad, Bethan Medina-Pritchard, James R. Paulson, Linfeng Xie, A. Arockia Jeyaprakash, Ian A. Prior, Leonid A. Mirny, Job Dekker, Anton Goloborodko, William C. Earnshaw. bioRxiv 2024.04.18.590027. https://doi.org/10.1101/2024.04.18.590027.
We used Hi-C, imaging, proteomics and polymer modeling to define rules of engagement for SMC complexes as cells refold interphase chromatin into rod-shaped mitotic chromosomes. Firstly, condensin disassembles interphase chromatin loop organization by evicting or displacing extrusive cohesin. Secondly, condensin bypasses cohesive cohesins, thereby maintaining sister chromatid cohesion as sisters separate. Studies of mitotic chromosomes formed by cohesin, condensin II and condensin I alone or in combination reveal new models of mitotic chromosome conformation. In these models, loops are consecutive and not overlapping, implying that condensins stall upon encountering each other. The dynamics of Hi-C interactions and chromosome morphology reveal that during prophase loops are extruded in vivo at ~1-3 kb/sec by condensins as they form a disordered discontinuous helical scaffold within individual chromatids
Feasibility Study of the CT Clock for Estimating Onset Time of Ischaemic Stroke
No full textIschaemic stroke is a devastating disease with high rates of death and disability affecting around 100,000 people annually in the UK. Effective treatments are only offered when the time of stroke onset is known and within specific limits. For the 20% where onset time is unknown or delayed, advanced imaging methods can identify people for safe and effective treatment. However, this advanced imaging is not always available. We have developed a method for identifying patients who can still be treated even without advanced imaging. The CT Clock uses only the non-enhanced CT brain scan that most patients with stroke receive upon arrival at hospital, to determine whether patients are eligible for treatment.
This project provides the first prospective clinical testing of the CT Clock in a single-centre (Royal Infirmary of Edinburgh, RIE) feasibility analysis. Between October 2023 and October 2024, we recruited 35 patients presenting to RIE with ischaemic stroke. We invited treating clinicians to apply our CT Clock method in real time, but we did not alter routine care pathways or otherwise involve patients. Participating clinicians including stroke physicians and radiologists provided 130 CT Clock assessments for the 35 recruited patients in their care.
This dataset includes all non-imaging data collected during the study and includes: anonymised patient demographics, baseline clinical data, date-time of stroke onset and CT, details of participating clinician, clinician's assessment of CT, clinician's experience of using the CT Clock method, expert assessment of CT at 14-day follow-up, final diagnosis.CT_Clock_Baseline_210325.csv - 35 participants: Age, sex, date & time of CT scan, date & time of symptom onset/wake-up/last known well, stroke severity (National Institutes of Health Stroke Scale, NIHSS), stroke sub-type.
CT_Clock_Clinician_ Assessments_210325.csv - 130 clinician assessments of 35 participant CT scans acquired at baseline: Clinician specialty & grade, location of visible ischaemic lesion OR expected side of brain affected, presence of dense artery, CT angiography/perfusion reviewed, if dense artery/CTA/CTP helped identify ischaemia on CT, attenuation measurements of ischaemic & normal brain, ease of finding & measuring ischaemia, ease of estimating location of ischaemia, time spent using CT Clock method.
CT_Clock_Expert_Follow-up_210325.csv - Expert review of imaging for 35 participant scans: Location of visible ischaemic lesion on baseline CT, presence of dense artery, chronic brain changes at baseline (old stroke lesions, small vessel disease), presence of relevant abnormalities on baseline CT angiography/perfusion, whether follow-up imaging helped identify ischaemia on baseline CT, attenuation measurements of ischaemic & normal brain, final diagnosis
Copper precipitation and carbon analysis
No full textQuantitative ICP-OES and ICP-MS data for all precipitation and solvent extraction experiments, infrared spectroscopic data, powder X-ray diffraction data, X-ray fluorescence data, life cycle inventory, nuclear magnetic resonance (NMR) spectroscopic data and matrix assisted laser desorption/ionisation mass spectrometry (MALDI-MS) data.Excel workbook: Raw_Data_Vance_Chatzisymeon_Morrison_Love comprising ICP, FTIR, PXRD and XRF raw data
Excel workbook: Life_Cycle_Inventory_Vance_Chatzisymeon_Morrison_Love comprising inventory data used for life-cycle analysi
Time-resolved 2D and 3D Imaging of Hydrogen and Brine Displacement Processes in Clashach Sandstone
No full textThis dataset contains: 1) Time-resolved (4D) tomographic images of steady state H2 and brine injections into untreated Clashach sandstone at 5 MPa pore fluid pressure, ambient temperature and a total flow rate of 20 µl min-1. Time-resolved imaging of the H2 and brine displacement processes was achieved by means of a 65 keV monochromatic beam with a bandwidth of 2×10-3 and the beamline’s scintillator-coupled PCO edge 5.5 imaging camera (‘Module 2’ with a 7.91 x 7.91 μm/pixel size and a field of view of 20 mm x 12 mm). A total of 900 projections with 20 milliseconds exposure time were recorded for each time-resolved µCT scan. Provided are reconstructions of the whole rock volume and H2- segmented subvolumes. 2) 2D-radiography of unsteady state hydrogen injection into a brine-saturated Clashach sandstone at 5 MPa pore fluid pressure and ambient temperature and a flow rate of 5 µl min-1. 2D-radiography used an exposure time of 25-milliseconds per frame and 900 frames per acquisition, with consecutive acquisitions running for 78 minutes. Provided are enhanced 2D images and a slow motion video, made from the same files
Steroid profiling by mass spectrometry in DexFem subjects
No full textThis dataset is mass spectrometry data from LC-MS/MS analysis of plasma and endometrial tissue from dexamethasone and untreated DexFem subjects. We previously published the DexFEM trial which showed in women with heavy menstrual
bleeding oral dexamethasone reduces menstrual blood loss. Here, we report pharmacodynamic
analysis exploring the likely mechanism for this effect. We studied oral dosing with
dexamethasone during the mid-luteal phase of two menstrual cycles (1.5 mg daily, 5 days) in
5 women with HMB (6 recruited aged 41-50 years, 1 withdrew before treatment). Steroid
hormones were profiled in serum and endometrium by liquid chromatography tandem mass
spectrometry (LC-MS/MS). We found that following oral dosing, dexamethasone reached the
endometrium, and that compared to preceding control cycle, cortisol (active), cortisone
(inactive), and intermediate 11-deoxycortisol, were reduced in all samples assessed, both
endometrial (n=4) and serum (n=5). Concentrations of androgens, androstenendione and
testosterone, were reduced in serum but not in all tissue samples. This proof-of-concept
pharmacodynamic study supports the inference that dexamethasone is effective in HMB by
altering endometrial glucocorticoid concentrations
CaFeFeNbO6 – an iron-based double double perovskite
No full textOrdering of cations is important for controlling properties of ABO3 perovskites, and CaFeFeNbO6 is the first example of an Fe-based AA’BB’O6 double double perovskite, with Ca2+/Fe2+ ordered on A-site columns, and Fe3+/Nb5+ at the octahedral B-sites. Substantial (37%) antisite disorder of the latter cations leads to spin glassy magnetism below a freezing transition at 12 K. The CaMnFeNbO6 analogue also shows substantial cation disorder and spin glassy behaviour. Comparison of synthesis pressures for ordered materials based on different A-site transition metals, suggests that pressures of at least 14-18 GPa will be required to discover the expected plethora of double double perovskites based on A’ cations smaller than Mn2+Files are magnetic and powder neutron diffraction data for the two samples shown in the publication Ji, K., Bedward, J.R., Li, Q., Manuel, P., Ritterc, C. and Attfield, J.P. (2023), "CaFeFeNbO6 – an iron-based double double perovskite", Chemical Communications 59, 6371 - 6374 ( https://doi.org/10.1039/D3CC01115A )