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Primary Versus Secondary Psychosis in a Patient With Congenital Liver Disease
No full textIn this article we report the case of a man with congenital liver disease who later developed psychotic illness and was diagnosed with schizophrenia. We illustrate how decompensation in liver function was associated with the exacerbation of psychotic symptoms. We discuss differential diagnostic challenges, and the possible overlapping neuropathology in these two conditions that may converge on glutamate/N-methyl-D-aspartate dysfunction. This patient\u27s case underscores the need for further research to elucidate the possible underlying mechanisms linking congenital liver disease and psychosis
Antibiotic-Induced Changes in Efflux Transporter Expression: A Key Factor in Pseudomonas aeruginosa Biofilm Resistance
Get PDFListed by WHO as an antibiotic-resistant priority pathogen, Pseudomonas aeruginosa(P.A.) is a serious threat in nosocomial infections. Its high antibiotic resistance is attributed to major mechanisms that can be categorized into intrinsic, acquired, and adaptive resistance. This study tests the ability of three commonly used antibiotics to inhibit new biofilm formation and eradicate mature biofilm growth, as well as investigate changes in the expression levels of selected genes coding for multidrug efflux pumps in P.A. planktonic cells and biofilms before and after treatment with antibiotics to provide a conceptual estimate of the activity of the efflux transporters that work to extrude antibiotics leading to a reduction in their effectiveness. Antimicrobial susceptibility testing was conducted with Ofloxacin (OFLX), Tobramycin (TOB), and Ceftazidime (CAZ) to determine Mean Inhibitory Concentration (MIC) and Mean Bactericidal Concentration (MBC) using microtiter plate-based biofilm assay and spectrophotometric quantification. Extraction of total RNA was performed from planktonic cultures, inhibition phase, and eradication phase P.A. biofilms. Real-time quantitative reverse transcriptase PCR was utilized to analyze the changes in expression of the mexAB, mexXY, and oprM genes. Three (3) antibiotics that have proven to show less resistance are OFLX, TOB, and CAZ when tested against overnight cultures of P.A. strain PA01. Results showed that OFLX is best for bactericidal properties, which is also supported by the viability assay data obtained from Propidium Iodide staining. Our study showed that the PAO1 strain is susceptible to OFLX for both inhibition and eradication of mature biofilms. TOB was most effective at higher concentrations in the eradication phas
Navigating Hypoglycemia in Diabetes Care: Clinical Management Strategies and Glucagon Treatment Options
No full textSummer 2024 SOM Alumni Connections
Get PDFKenneth Theobalds To Be Honored at NYMC’s Annual Golf Tournament NYMC Honors the Class of 2024 at 165th Commencement Ceremonies NYMC Opens New Online Store Founder\u27s Dinner 2024 Days of Giving Raises 2.6M FDA Grant for Infant CMV Infection Research NYMC and Regeneron Debut Neighborhood Science Seminar Series Department of Surgery Hosts 20th Annual Louis R.M. Del Guercio Distinguished Visiting Professorship and Research Day NYMC Students’ Altruism Shines with Woodfield Cottage Youth Initiative NYMC Reflects on the Legacy of Medicine During the Holocaust for Yom Hashoah Students Pay Tribute to Their First Patients During Convocation of Thanks NYMC Hosts TB in the Hudson Valley Symposium Medical Students Join Lifesaving Organ Transplant Procurements Department of Radiation Medicine Enrolls First Patient in Nation in Prostate Cancer Clinical Trial Faculty Spotlight: Rebecca A. McAteer Martin, M.D. \u2708, Shares Her Mission in Healing Faculty Spotlight: From Classical Music to Hi-Tech Apps, Eric L. Altschuler, M.D., Ph.D., Shares His Passion for Neuroscience and Rehabilitation Medicine Student Spotlight: Study Reveals Concerning Link Between Growth Hormone Therapy and Growth Plate Fractures in Children Student Spotlight: Miriam Katz, M.P.H., Shares Her Research on Digital Hypertension Management Tools Alumni Spotlight: Ashley Sacks, M.D. \u2724, Embarks on OB/GYN Residencyhttps://touroscholar.touro.edu/nymc_som/1022/thumbnail.jp
Spring 2024 SHSP Alumni Connections
Get PDFNYMC Annual Days of Giving Set for March 26 and 27 CDM Provides Hands-On Training for First Responders D.P.T. Class of 2025 Present Community Service Projects NYMC NSSLHA Chapter Hosts Fundraiser for Smile Train Students Shine at 2023 Multidisciplinary Community Outreach NYMC Celebrates Faculty Authorship at 30th Annual Recognition NYMC Hosts “Ninety Minutes: The Medical Magazine of the Web” Student Spotlight: Dr. P.H. Candidate Advocates for Long Term Care Through the Media Alumni Spotlight: SLP Alumna Opens Local Private Practice in Honor of Late Sister Alumni Spotlight: D.P.T. Alumnus Finds Solace in Writing After Cardiac Eventhttps://touroscholar.touro.edu/nymc_shsp/1024/thumbnail.jp
