19043 research outputs found
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InTouch Week of August 25, 2025
No full textEnhancing Campus Operations Celebrating NYMC and Metropolitan Hospital New Speech-Language Pathology Students Begin Their Academic Journey Historical Hahnemann Hospital Clock Adorns Sunshine Cottage Lobby Psoriasis and Cardiovascular Disease Link Not Clearly Recognized by Patients Student Spotlight: SOM Student Helps Develop Innovative Anesthesia App for WMC Residentshttps://touroscholar.touro.edu/in_touch/1372/thumbnail.jp
The Role of Palliative Care in Cardiovascular Disease
No full textThe American Heart Association has recommended that palliative care be integrated into the care of all patients with advanced cardiac illnesses. Notwithstanding, the number of patients receiving specialist palliative intervention worldwide remains extremely small. This review examines the nature of palliative care and what is known about its delivery to patients with cardiac illness. Most of the published literature on the subject concern advanced heart failure; however, some data also exist regarding patients with heart transplantation, pulmonary hypertension, valvular disease, congenital heart disease, indwelling devices, mechanical circulatory support, and advanced coronary disease. In addition, outcome data, certification requirements, workforce challenges, barriers to implementation, and a potential caveat about palliative care will also be examined. Further work is required regarding appropriate means of implementation, quality control, and timing of intervention
Low-Dose Oral Minoxidil for Androgenetic Alopecia Is Not Associated With Blood Pressure Changes in Patients Also Taking Other Antihypertensive Medications: A Multicenter Cohort Study Using Trinetx
No full textLetter to the FDA Proposing Major Changes in the US Clozapine Package Insert Supported by Clozapine Experts Worldwide. Part II a Review of Fatal Outcomes in US Pharmacovigilance Data and Proposed Changes
No full textPurpose/Background: This is the second part of a 2-part article that proposes improving the United States (US) clozapine package insert. Part II focuses on fatal outcomes and the 5 boxed warnings, 4 specifically for clozapine: severe neutropenia, seizure, orthostatic hypotension and myocarditis, and 1 for all antipsychotics (elderly with dementia). Methods: US reports to the World Health Organization\u27s global pharmacovigilance database were analyzed from clozapine\u27s introduction to January 15, 2023. Findings/Results: The US was the top reporter worldwide for clozapine with 56,003 reports and 9587 associated fatal outcomes. The 4 clozapine boxed warnings were associated with 534 fatal outcomes (218 with severe neutropenia, 131 with seizures, 125 with orthostasis, 36 with myocarditis, 24 with cardiomyopathy, and 0 with mitral valve prolapse). With no boxed warnings, pneumonia was associated with 674 fatal outcomes and increased white blood cell count (a sign of infection) with 596 fatal outcomes. After considering overlaps, pneumonia and increases in white blood cell count explained 900 fatalities, or 9.4% of 9587 fatal outcomes. The Food and Drug Administration continues to focus on severe neutropenia which was associated with only 218 or 2.3% of fatal outcomes, whereas 97.7% of fatal outcomes reported in US clozapine-treated patients had another cause. Implications/Conclusions: To help prevent future deaths in clozapine-treated patients, the clozapine package insert should focus on fatal outcomes during infections. Part II offers detailed solutions regarding current boxed warnings and lack of a warning for pneumonia and other infections. The Supplementary Material includes letters of support from 124 non-US clozapine experts from 44 countries/regions who support Parts I and II
Excellent Long-Term Survivorship, Radiologic and Functional Outcomes of Operatively Treated Tibial Plateau Fractures
No full textPurpose: Long-term reports of operative tibial plateau fractures are scarce. This study aimed to define long-term knee survivorship with total knee arthroplasty (TKA) as the primary endpoint, assess radiographic and functional outcomes, and the relationship between reduction and functional outcomes. Methods: Over 21 years, 170 patients were identified with operatively managed tibial plateau fractures treated by two orthopaedic trauma surgeons (109 unicondylar, 61 bicondylar). Survivorship analysis was performed to identify TKA conversion risk factors. Final follow-up radiographs were assessed for osteoarthritis severity, and clinical and functional outcomes were analyzed (KOS-ADLS, SF-12, and NRS-Pain). Results: In unicondylar fractures, survivorship free of TKA was 93.6% (95% CI 88.7%–98.5%) at 10- and 15-years. Survivorship free of TKA for bicondylar fractures was 88.5% (95% CI 80.5%-96.5%) at 10-years and 84.3% (95% CI 73.1%–95.5%) at 15-years. Bicondylar involvement and non-anatomic reduction were independent risk factors for TKA (HR 2.7, HR 3.7; respectively). Bicondylar fractures demonstrated severe osteoarthritis more frequently than unicondylar (p = 0.043). At average 10-year follow-up (2–24 years), mean KOS-ADLS was 68.7 ± 12.5. Unicondylar patients had increased mean KOS-ADLS compared to bicondylar (71.4, 63.1, respectively; p = 0.005). Mean SF-12 was similar between groups. Conclusion: Approximately 10% of operative tibial plateau fractures underwent TKA at 15-years; this rate approached 15% in bicondylar fractures. Bicondylar fractures had 2.7X higher TKA risk. In unicondylar fractures, non-anatomic reduction was associated with 3.7X higher TKA conversion risk. While both groups had similar SF-12 scores, bicondylar had significantly lower KOS-ADLS scores. Anatomic reduction is critical to prevent TKA conversion in unicondylar fractures
Efficacy and Safety of Bictegravir Plus Lenacapavir: 48-Week Outcomes in People With HIV-1 Who Are Virologically Suppressed on Complex Antiretroviral Regimens at Baseline
No full textARTISTRY-1 is a phase 2/3 trial of bictegravir (BIC; 75 mg) plus lenacapavir (LEN; 25 mg or 50 mg) versus complex antiretroviral therapy regimens in 128 virologically suppressed people with HIV-1. At 48 weeks, BIC + LEN (at either LEN dose) was highly effective at maintaining virologic suppression and was well tolerated
Occupational Therapy Student Guide to Range of Motion and Manual Muscle Strength Testing
No full text2025
This Open Educational Resource (OER) is designed to enhance your understanding of Range Of Motion (ROM) and Manual Muscle Testing (MMT), two foundational skills for occupational therapy practitioners. These assessments are critical for evaluating a client’s movement and functional abilities during occupational performance, guiding intervention planning, and clinical decision-making.
The goal of this supplemental lab manual is to provide clear, affordable, accessible content that supports hands-on learning and supplements classroom teaching. Occupational therapy students can use this OER to assist with practical application. This resource helps students build competence and confidence in performing ROM and MMT assessments accurately as they prepare for their class lab practicals. This OER allows students the ability to access the information through digital access anytime.
This OER site reinforces content taught in the lab portion of the OTHN 334 class, with step-by-step instructions, visuals, and embedded YouTube videos.https://touroscholar.touro.edu/opentextbooks/1016/thumbnail.jp
InTouch Week of January 20, 2025
Get PDFNew Study Reveals Obese Children Face Higher Risks in Vehicle Strikes Inaugural Drs. Joel and Judith R.F. Kupersmith Endowed Lecture Set for January 28 Pet the Stress Away Brings Comfort to Campus Student Spotlight: D.P.T. Student Shares Research on Robotic Technology Faculty Spotlight: From Pupil to Professor: Alumni Lighting the Way at NYMC Faculty Spotlight: Dr. Rossi Helps Others Move Forwardhttps://touroscholar.touro.edu/in_touch/1348/thumbnail.jp
