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    Intraovarian Platelet-Rich Plasma (PRP) Infusion Appeared to Benefit Low Prognosis IVF Patients; However, When Compared to Controls, No Significant Benefit Could Be Confirmed

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    Purpose: To assess whether in-office intraovarian PRP injections among patients with a history of a low euploid embryo yield following freeze-all PGT-A IVF cycle improves transferable embryo yield when compared to controls. Materials and methods: A retrospective case–control study, between March 2022 and December 2024 where all poor outcome patients who underwent in-office intraovarian PRP injection prior to a repeat freeze-all PGT-A IVF cycle were compared to controls with no intervention between cycles. The primary outcome was transferable embryo yield. Secondary outcomes included: blastocyst yield, aneuploidy rate, and euploid yield. Results: Thirty-two patients met the inclusion criteria and were compared to 309 controls. Mean age for the PRP and control group were 38.3 ± 3.1 and 38.4 ± 3.7 (p = 0.91) respectively. Mean AMH for the PRP group was 1.6 ± 1.1 ng/mL as compared to 1.5 ± 1.0 ng/mL (p = 0.34). Following PRP the blastocyst, euploid and transferable embryo yield increased; however, when compared to controls, there were no differences in IVF outcomes. For patients with an AMH ≥ 1, the euploid yield and transferable embryo yield increased by fivefold; however, there was no difference when compared to the control. For patients with an AMH \u3c 1, there were no differences in euploid or transferable embryo yield following PRP. Conclusion: Although there was an improvement in transferable embryos yielded following PRP, no difference was observed compared to the control group, as the control with a poor initial cycle experienced regression to the mean which may also be a source of bias in the PRP group

    From Childhood to Adult Cognitive Health: Analyzing Adverse Experiences and Subjective Cognitive Decline using BRFSS 2020-2023 Dataset

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    The chronic impact of early-life experiences on long-term health is a critical area of investigation, especially regarding cognitive health in adulthood. Adverse childhood experiences (ACEs) have been linked to an increased risk of developing various health issues in adulthood, including mental health disorders, substance abuse, and chronic diseases. The connection between ACEs, substance abuse and cognitive health, particularly subjective cognitive decline (SCD), remains relatively underexplored. The aim of this study is to examine the intricate relationships between ACEs, alcohol abuse, and SCD in adulthood. This study draws on trauma theory and the biopsychosocial model to conceptualize the long-term impact of childhood adversity on cognitive functioning and alcohol dependence in adulthood. This is a retrospective, cross-sectional study that includes 41,687 U.S. adults aged 45 years and above from the BRFSS dataset from 2020 to 2023 who responded to the ACE and SCD modules. The primary variables were ACEs exposure and adult alcohol abuse. The outcome variable was SCD in adulthood. Covariates included demographic and socioeconomic factors such as age, sex, race/ethnicity, education level, and employment status. A survey-weighted chi-square test was used for bivariate analysis, and survey-weighted logistic regression models were employed to assess the effect of ACEs and adult alcohol abuse on SCD, controlling for each covariate. ACEs and adult alcohol abuse were each strongly associated with SCD in adulthood (High ACEs = aOR: 3.43, 95% CI: 2.95–3.98, p \u3c 0.001; Low ACEs = aOR: 1.69, 95% CI: 1.49–1.91, p \u3c 0.001; adult alcohol abuse = aOR: 1.22, 95% CI: 1.04–1.42, p = 0.013). Their interaction did not show a statistically significant combined effect on SCD (p = 0.414). Employment status and education level had a protective role in iideveloping SCD in adulthood among the participants. The public health impact of childhood adversity is evident in the very strong association between childhood adversity and cognitive decline. Any type of childhood adverse events and all forms of substance abuse have a negative impact on cognition, be it at an older age or a younger age. Keywords: adverse childhood experiences, adult alcohol abuse, subjective cognitive decline, BRFSS

    Reproductive Health Literacy Scale: A Tool to Measure the Effectiveness of Health Literacy Training

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    BACKGROUND: Refugee women\u27s reproductive health (RH) outcomes have been impacted by several factors, including experiencing war, lack of access to healthcare, and possible gender-based violence. After resettlement, low health literacy, financial difficulties, cultural and linguistic barriers, and unfamiliarity with the healthcare system also add to the preexisting barriers. Although several efforts have focused on health education and improving health literacy among refugee women, there has not been a validated tool to measure the effectiveness of these trainings and their possible impact. This study aims to adapt a culturally and linguistically appropriate survey that helps address this gap. METHODS: We conducted a literature review to identify the existing tools and identified possible domains and items supporting RH literacy measures. The identified items were collected and adapted as a single scale with three domains: (a) general health literacy, measured with HLS-EU-Q6, (b) digital health literacy, measured with eHEALS, and (c) reproductive health literacy, measured through a composite of the Cervical Cancer Literacy Assessment Tool (C-CLAT) and the Refugee Reproductive Health Network (ReproNet) postpartum literacy scale. After content validity and face validity of the adapted scale, it was translated into Dari, Arabic, and Pashto and was administered to participants of RH literacy training sessions. RESULTS: A total of 67 Dari, 53 Arabic, and 64 Pashto-speaking refugee women completed the survey. The mean scores obtained between the three language groups were similar in the domains of digital health literacy and reproductive health literacy (p \u3e 0.05), whereas the scores for general health literacy were not (p \u3e 0.05). The inter-item reliability score for the domains of general health literacy, digital health literacy and RH literacy across all three language groups was above α = 0.7. CONCLUSION: This scale addresses the need for validated tools to measure reproductive health literacy. It has the promise to provide a tool for assessing the effectiveness of health interventions on health literacy. Future applications can utilize this scale to investigate the differences in health literacy in refugee populations speaking Dari, Pashto, and Arabic

    InTouch Week of March 3, 2025

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    Fawaz Al-Mufti, M.D., Leads Stroke Trial Exploring Cognitive Benefits of Thrombectomy Faculty Spotlight: From Pupil to Professor: Adam Karp, M.D. \u2719 Student Spotlight: Janice Fung’s Quest to Combat Plague Through Vaccine Innovation Alumni Spotlight: The Extraordinary Life of Donald Doyle, M.D. ‘67https://touroscholar.touro.edu/in_touch/1354/thumbnail.jp

    InTouch Week of March 24, 2025

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    NYMC Students Shine on Match Day 2025 LaShari Valentin, Ph.D., M.B.A., Named Designated Institutional Official Predatory Journals on the Rise: How the Phillip Capozzi, M.D., Library Can Help You Publish Safely Pet the Stress Away Brings Comfort to NYMC NYMC Annual Days of Giving Set for March 25-26 Student Contest Winner’s Designs are Now Available Faculty Spotlight: NYMC Faculty Member and Alumna Appointed to Public Health Director for Sullivan County Student Spotlight: Justinian Michaels Aspires to Bring Athletes Back to the Gamehttps://touroscholar.touro.edu/in_touch/1357/thumbnail.jp

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