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Ha-Tov v’ha-Meitiv: Contemporary Scholarship in Jewish Studies—Essays In Honor of the 50th Anniversary of Touro University
Out of Print Books We Love: The Last Attachment: The Story of Byron and Teresa Guiccioli by Iris Origo
The Psychometric Properties of the Modified Fear of Falling Avoidance Behavior Questionnaire in Parkinson’s Disease and Older Adults
Enhancing Safety and Independence with Transfers: A Guide to Transfer Devices for Case Managers
Vertical Transmission of SARS-Cov-2 Delta-Variant in a Preterm Infant
BACKGROUND: As SARS-CoV-2 continues to be relevant and cause illnesses, the effect of emerging virus variants on perinatal health remains to be elucidated. It was demonstrated that vertical transmission of SARS-CoV-2 is a relatively rare event in the original SARS-CoV-2 strain. However, very few reports describe vertical transmission related to the delta-variant. CASE PRESENTATION: We report a case of a preterm male neonate born to a mother with positive SARS-CoV-2 and mild respiratory complications. The neonate was born by cesarean section due to fetal distress. The rupture of the amniotic membrane was at delivery. The neonate had expected prematurity-related complications. His nasopharyngeal swabs for RT-PCR were positive from birth till three weeks of age. RT-ddPCR of the Placenta showed a high load of the SARS-CoV-2 virus with subgenomic viral RNA. RNAscope technique demonstrated both the positive strand of the S gene and the orf1ab negative strand. Detection of subgenomic RNA and the orf1ab negative strand indicats active viral replication in the placenta. CONCLUSIONS: Our report demonstrates active viral replication of the SARS-CoV-2 delta-variant in the placenta associated with vertical transmission in a preterm infant