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Unusual Presentation of Complicated Relapsing Fever With Spontaneous Hemoperitoneum Mimicking Surgical Acute Abdomen: A Case Report
No full textBackground: Louse-borne relapsing fever (LBRF) is a prevalent disease in Ethiopia, affecting malnourished and impoverished populations. Historically fatal, mortality has decreased to less than 5% with antibiotics. Symptoms include high fever, rigors, myalgia, hepatosplenomegaly, jaundice, and petechial rash. Diagnosis is challenging due to Giemsa-stained blood films and PCR in resource-limited settings. Case Presentation: A 29-year-old Ethiopian patient experienced abdominal pain, vomiting, diarrhea, and high fever for 3 days. Physical examination revealed low blood pressure, oxygen saturation, tachycardia, decreased air entry, and a tender abdomen. A bedside ultrasound revealed bilateral pleural collection, dense B lines, an air bronchogram, and abdominal collection. The patient had thrombocytopenia, leukocytosis, acute kidney injury, elevated transaminase levels, and Borrelia spirochetes in her blood. The patient recovered fully within 8 days after respiratory failure. Discussion: This case highlights the importance of recognizing relapsing fever (RF) as a critical mimic of surgical abdomen, preventing unnecessary surgical interventions in hemorrhagic abdominal emergencies. Conclusion: A life-threatening Borrelia-induced hemoperitoneum in Ethiopia was successfully managed, despite complications of surgical acute abdomen with hemoperitoneum, severe thrombocytopenia, and multiorgan involvement, highlighting the importance of infectious consideration in acute abdomen
InTouch Week of January 13, 2025
Full text linkNYMC Administers First Novel Inhaled mRNA Therapy for Cystic Fibrosis in the U.S. NYMC Students Set Their Resolutions for 2025 Research Highlights Deadly Combination of COVID-19 and Chronic Liver Disease Dr.P.H. Program Now Includes Fully Remote Option Dr. Xiu-Min Li\u27s Advances in Medicinal Herbal Research Holocaust Remembrance Day and Black History Month: The Segregated U.S. Military and the Liberation of a Concentration Camp Faculty Spotlight: From Pupil to Professor: Alumni Lighting the Way at NYMChttps://touroscholar.touro.edu/in_touch/1347/thumbnail.jp
The Impact of Childhood Sexual Abuse on Resilience and Empathy in Adulthood: Exploring Psychological Outcomes and Interrelationships Among Adult Survivors
No full textBackground: Childhood sexual abuse (CSA) is a traumatic experience that can have lasting psychological impacts on its survivors. Resilience and empathy are crucial for the recovery and social functioning of CSA survivors. However, the relationship between CSA and these constructs remains complex and not fully understood. Purpose: This study aimed to determine whether significant differences exist between individuals who have experienced CSA and those who have not. Additionally, the study also investigated the relationship between empathy and resilience. Methodology: A cross-sectional study was conducted with 36 adult participants, including CSA survivors and non-CSA participants. The Connor-Davidson Resilience Scale was used to assess resilience, while the Empathy Quotient was used to assess the participants\u27 empathy. Results were analyzed using the Mann-Whitney U test, independent-samples t-test, and simple linear regression. Results: The results indicated no statistically significant differences between CSA survivors and non-CSA survivors regarding resilience (U = 310.5, z = -.716, p = .474) and empathy (p = .763). However, simple linear regression showed a moderate positive and significant relationship between empathy and resilience, F (1, 32) = 73, p = .009, R2 = .193. Conclusion: The findings highlight the dynamic nature of resilience and empathy, suggesting that multiple factors beyond the experience of CSA alone may influence these constructs. Future research should incorporate larger sample sizes and qualitative approaches to better understand the complex interplay between resilience, empathy, and external support systems in CSA survivors
Global, Regional, and National Burden of Pulmonary Arterial Hypertension, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021
No full textMeta-Analysis of Phase II/III Randomized Controlled Trials (RCTs) to Evaluate the Incidence of Hand-Foot Skin Reaction (HFSR) or Palmar-Plantar Erythrodysesthesia (PPE) Syndrome in Patients with Gastrointestinal (GI) Cancers Treated with Fruquintinib
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InTouch Week of June 2, 2025
Full text linkNYMC Celebrates the Class of 2025 at 166th Commencement SOM Awards Ceremony Honors Excellence SHSP Dean’s Awards Recognize Rising Health Leaders GSBMS Honors Excellence in Biomedical Science at Annual Awards Ceremony TCDM Celebrates the Class of 2025 Noninvasive Method for Early Intraventricular Hemorrhage Detection in Preemies Revealedhttps://touroscholar.touro.edu/in_touch/1366/thumbnail.jp
Pre-Treatment Seizures and Cognition at the Time of Focal Epilepsy Diagnosis
No full textObjective: People with focal epilepsy experience one or more seizures prior to diagnosis. The Human Epilepsy Project (HEP) was a prospective study enrolling people with newly diagnosed focal epilepsy. It collected information including cognitive testing at the time of enrollment. This was completed utilizing a computerized test battery called the Cogstate Brief Battery (CBB). A prior analysis found that enrollment CBB test scores were below that of age matched controls and that performance on testing was not independently associated with the longer-term development of treatment resistance over the course of the HEP study. The present study assesses the impact of pretreatment seizures on cognition at time of diagnosis, considering time-to-treatment initiation in relation to seizure onset, pre-treatment seizure frequency, and pretreatment seizure classification. Methods: Participants with newly diagnosed focal epilepsy and no other major medical comorbidities or intellectual disability (estimated IQ \u3e 70) were enrolled between June 29, 2012, and September 1, 2019. A subset of the 448 enrolled participants (N = 183) were over 18 years old, had complete HEP enrollment data that included pre-treatment seizure histories, and complete enrollment CBB testing for analysis in this study. Performance on enrollment CBB testing was modeled using multiple linear regression with pre-treatment seizure characteristics including seizure type and duration between seizure onset and treatment initiation, controlling for other key baseline participant characteristics. Results. There were no independent associations between cognitive measures on the CBB at the time of enrollment and pre-treatment seizures after correcting for potentially confounding variables. Z-scores for the attention composite on CBB (an average of Identification and Detection tests) were not associated with a global pre-treatment seizure score that quantified time with seizures (days) and seizure count by seizure type (motor, non-motor, bilateral tonic clonic) (p = 0.29). Similarly, z-scores for the memory composite (an average of the One Card Learning test and One Back tests) were not associated with the pre-treatment seizure score (p = 0.1). No additional independent associations were found to be significant between z-scores for attention or memory composites and other potential explanatory variables. Significance: This study highlights an important finding for people who develop focal epilepsy and otherwise are in good health: pre-treatment time-limited seizures do not have an independent impact on cognition early on, as measured by a brief validated cognitive screening test. This suggests that that cognition at the time of epilepsy diagnosis may be more strongly related to underlying etiology, chronic disease, and comorbidities