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Case Report: Todd’s Paralysis In A Patient With An Extensive Stroke History
Full text linkHere we present the case of a 70-year-old patient who presented to the emergency department with altered mental status, left-sided gaze preference, left-sided hemineglect, and inability to follow commands. He had a past medical history of seizure activity and cerebrovascular accident (CVA) with residual dysarthria and was on apixaban. His symptoms began after seizure activity and improved gradually. He was ultimately diagnosed by stroke neurology as having had an episode of Todd’s Paralysis. The differential diagnosis for patients for altered mental status with neurological deficits can be vast, but, in general, Todd’s Paralysis can be an ischemic stroke mimic upon presentation to the emergency department
Maternal Health and Nutrition: Combating Maternal Mortality Through Proper Nutrition
Full text linkMaternal mortality is an increasing concern in the United States. According to the WHO, from 2018-2022 the Maternal Mortality Rate (MMR) was 23.3 deaths per every 100,000 live births. New Jersey\u27s MMR exceeded this average at 26 per 100,000 during the same period, with 91% of cases deemed preventable. While medical care plays a crucial role, research shows that non-medical determinants such as food insecurity, lack of nutritional education, limited access to transportation, and systemic barriers to health care contribute significantly to maternal health outcomes. Among these factors, proper nutrition plays a critical role before and during pregnancy, particularly in low socioeconomic populations. Existing global efforts, such as the HEAR her campaign and the expansion of telemedicine, aim to address maternal mortality through professional support and improved communication. However, many individuals remain unaware of these resources or are unable to access them due to systemic and logistical barriers. At the local level, organizations like Nurture NJ, The Cooperative, and Baby’s Best Start strive to reach underserved populations and provide essential support. A group of students in The Health Careers Opportunity Ambassador Program (HCOP), federally funded to prepare disadvantaged students for serving vulnerable populations, has partnered with Baby\u27s Best Start to enhance their curriculum with an emphasis on prenatal nutrition education as a strategy to combat maternal mortality
Advances in and Applications of Capillary Scale Liquid Chromatography
Full text linkAnalytical-scale high performance liquid chromatography (HPLC) is one of the most widely used analytical techniques in the world. Efforts have been made to reduce the mobile phase consumption of HPLC by reducing the inner diameter (I.D.) of the column. By using capillary-scale columns (\u3c 0.5 mm I.D.), separations can be performed with orders of magnitude less solvent consumption. This work describes advances made to capillary scale instrumentation as well as applications enabled by these advances. A compact capillary-scale LC was used for the analysis of numerous pharmaceutical and illicit drug compounds for point of need analysis. A miniaturized mass spectrometer was coupled to this instrument for on-line reaction monitoring within a standard chemical fume hood. Kinetic profiles of commercially available capillary columns were developed in order to provide guidance to others during column selection. The implementation of a column oven improved the analysis of large biopharmaceuticals. Several critical quality attributes of monoclonal antibodies including fragmentation, charge variants, and glycosylation profiles were able to be determined on the capillary scale. These results will help to make capillary-scale liquid chromatography a more viable solution for chromatographic analysis
NEW STUDENT ORIENTATION PROGRAMS: UNDERSTANDING THE PERCEPTIONS AND EXPERIENCES OF FIRST-GENERATION COMMUNITY COLLEGE STUDENTS
Full text linkThis study examines first-generation community college students\u27 perceptions of New Student Orientation programs. The research questions focus on specific aspects of students\u27 experiences and transitions to gain an understanding of their perspectives. The objective is to see if there is a connection between what researchers ascertain are the most valuable experiences for new students and what students feel and perceive while enrolled in their first semester of college. Qualitative data was collected to provide targeted insights for improving orientation programs and practices. The research questions focused on understanding specific aspects of students’ orientation experiences and their impact on their college transition. Key findings highlighted the value of several program components, including: student-to-student connections and advice for navigating common challenges; interactions with faculty; training on academic resources such as the learning management system; and access to campus support services (counseling, advising, and tutoring). These findings offer critical information for identifying gaps in orientation programs. This study empowers college administrators and faculty to critically examine their campus programs, assessment practices, and learning strategies, prioritizing student input in this process
Lecture Capture Transcripts: Use and Perceptions on Utility
Full text linkThis project focuses on student use and perceived utility of the transcripts created for all recorded lectures in the Synergistic Guided Learning (SGL) curriculum track. This poster will present our findings from a survey conducted with first year Osteopathic Medical Students (OMS-1) in Spring 2025
Teaching Students to Provide Effective Feedback with the Situation-Behavior-Impact (SBI) Framework
Full text linkWe often ask medical students to provide feedback to each other and the faculty. However, we do not necessarily teach them to provide effective, actionable feedback. This research focused on the impact of providing students with a 1-hour session training them to utilize the Situation-Behavior-Impact (SBI) feedback model
DEVELOPMENT AND PILOT EVALUATION OF A MATH INTERVENTION PROGRAM TO INCREASE NUMBER SENSE PROFICIENCY OF SECOND GRADE STUDENTS
Full text linkStudents continue to function below grade level proficiency in math and thus, the need for effective intervention. The purpose of this study was to develop and examine the efficacy of a targeted number sense intervention for second grade students. Specifically, the study examined the benefits of an intervention, analyzed number sense as an essential foundational skill, and determined if proficiency in number sense leads to math proficiency. Employing a quasi-experimental design, an intervention was implemented in 14 weeks for students who demonstrated a deficit in number sense and outcomes were assessed using multiple measures. Primary findings indicated that students who completed the intervention showed a significant improvement in number sense proficiency. Moreover, students demonstrated higher proficiency in number and operations and measurement data compared to their non-intervention peers. In terms of math attitude, students had relatively higher levels of positive attitude in math before and after the intervention. Qualitative findings from the focus group interview of teachers indicated that students demonstrated active engagement with the math lessons and activities throughout the intervention. The findings of the study were discussed in light of current literature and evidence-based practices in teaching and learning basic math skills. Policy recommendations and study limitations were also addressed
Recruitment and Retention of Men of Color in a Higher Education Initiative Program
No full textThis thesis is on the recruitment and retention of men of color in higher education initiative programs. The study focuses on the Project Educate Men program at Mid-Atlantic University. The purpose of the study was to understand how recruitment and retention could be improved in programs like Project Educate Men and what makes students who enter through such programs successful and unsuccessful. This study also discusses mentorship relationships between mentors and their mentees and what makes for strong relationships and communication amongst the individuals. The findings in this multiple methods study yielded that a program like Project Educate Men is effective and needed, but having a male of color do the recruiting for the program could help increase the recruitment numbers and lead to increased numbers in retention numbers. This was also suggested as a recommendation for the program. In addition to the latter being a recommendation from the findings, another recommendation was to evaluate the scholar and mentor relationship at the end of each academic year, because every relationship is different
The Effect of Birthweight and Gestational Age on Cognitive Function in Midlife: the Bogalusa Heart Study
No full textBACKGROUND: Although the relationships between birthweight, gestational age (GA), and cognitive function (CF) before midlife have been demonstrated, the relationships after midlife and potential racial disparities remain inconclusive. This study examined the association between birthweight, GA, and midlife CF stratified by race.
METHOD: 1,032 subjects from the Bogalusa Heart Study (67% Whites, 33% Blacks, mean age 48.1 ± 5.3 years) were studied. Cognition was assessed with tests measuring verbal episodic memory, working memory, attention, graphomotor information processing speed, and global CF. Each test was standardized by sex and age, then averaged. The global CF was computed by averaging all cognitive test scores. Standardized scores from the Wide Range Achievement Test-IV (WRAT- IV)-Reading subtest and the Wechsler Adult Intelligence Scale- IV (WAIS-IV)-Vocabulary subtest measured achieved education. Multivariate linear regression was used to estimate the association.
RESULTS: A 100-gram increase in birthweight was associated with an increase of 0.007 standardized units in global CF (SE: 0.003; p = 0.016), 0.007 in working memory (SE: 0.003; p = 0.041), and 0.012 in graphomotor processing speed (SE: 0.004; p = 0.010). Stratified by race, the associations between birthweight and global CF and CF subdomains were not statistically significant in either race, likely due to reduced power, as the estimates in both races showed similar effect sizes to those in the total sample. No differences were observed in CF subdomains among small for GA, appropriate for GA, and large for GA groups. GA, analyzed as a continuous variable, was not associated with CF. However, in preterm births, it was associated with better global CF, working memory, and graphomotor information processing speed, while there was no association in term-born births.
CONCLUSIONS: The impact of birthweight on the global CF remained in middle age, while the impact of birthweight adjusted for GA did not. GA as a continuous variable was not associated with CF, except in preterm individuals, where it was associated with better CF. These results suggest that birthweight may influence CF in midlife, and GA may play a role, particularly in those born preterm
Case Report: Solitary Adrenal Metastasis from Esophageal Adenocarcinoma
No full textINTRODUCTION: Solitary adrenal metastasis from a primary esophageal malignancy is relatively rare. While there are case reports of aggressive treatment with esophagectomy and adrenalectomy providing long-term survival, the treatment paradigm is not well defined. Complications from esophageal adenocarcinoma and its treatment can significantly impact the patient\u27s quality of life and prognosis.
CASE PRESENTATION: Our patient was treated with systemic therapy and, although he initially had a complete response, he later experienced local disease progression along with the development of additional metastatic sites. The patient began FOLFOX, a standard chemotherapy regimen for esophageal/gastric cancer. He experienced side effects such as fever, malaise, and constipation, which were symptomatically managed. Given these side effects, the patient\u27s FOLFOX regimen underwent a 25% dose reduction of the 5FU bolus. A PET/CT scan after three months showed a marked response to chemotherapy, with complete resolution of detectable disease. The patient reported fatigue, bone pain managed with Neulasta, nausea controlled with antiemetics, and neuropathy in his feet. The patient then began a new chemotherapy regimen with Taxol/Ramucirumab with dose modifications in response to side effects. Continued adjustments to the treatment and dosages were made for progressive side effects and the patient elected to receive palliative radiation to the esophagus, along with holistic supportive care. The treatment plan shifted to palliative care, focusing on quality of life, rather than curative, due to the complexities of his cancer.
CONCLUSION: While aggressive treatments may offer hope for a cure in select patients with isolated adrenal metastasis from esophageal cancer, the general approach should remain cautious, with systemic therapy as the first line of defense. This case highlights the need for careful selection to identify patients who may benefit from aggressive surgical treatment. Ongoing research and clinical trials are needed to better define treatment protocols and improve outcomes for this challenging patient group