Sultan Zainal Abidin University

UniSZA Institutional Repository
Not a member yet
    8142 research outputs found

    Prevalence of eating disorder risk and its associated factors among high school adolescents in Terengganu, Malaysia

    No full text
    Eating disorder is most commonly occur among adolescents due to weight concern and body dissatisfaction. Screening for eating disorders based on early identification of an eating disorder risk factor can lead to early treatment, thereby reducing serious complication and psychological complications. This study aimed to determine the prevalence of eating disorder risk and its associated factors among high school adolescents. A cross-sectional survey was conducted among 620 school-adolescents aged between 14 and 18 years from 11 secondary schools in Terengganu. Cluster sampling was applied and a self-administered questionnaire was used to assess 4 main components of the study: Eating Disorder Risk, Sociodemographic Factors, Substance Misuse Index and Psychological Factor. Eating Attitude Test (EAT-26) is used to assess risk of eating disorder as it has 3 subscales to assess an individual’s behaviours, thoughts on dieting, bulimia and food preoccupation and oral control. Substance Misuse Index drug is divided into 2 main categories licit and illicit drugs. Psychological factors was measured using validated Malay version of strength and difficulties questionnaires (SDQ). Prevalence of eating disorder risk among schoolgoing adolescents were 32.3%. The prevalence of eating disordered risk was higher among girls (18.4%) as compared to boys (13.9%). It was independently associated with emotional problem (p=0.028, Adjusted OR 1.15, CI 1.02, 1.30) and peer problem (p=0.004, Adjusted OR 1.23, CI 1.07, 1.42) identified using SDQ after adjusting other variables. Increasing age also increased the risk for eating disorder (p=0.014, Adjusted OR 1.20, CI 1.04, 1.38). It was not significantly associated with body mass index (BMI), or any history of any form of previous abuse. Adolescents with emotional and peer problems are at risk for eating disordered. It is crucial to screen adolescents identified with these problems for eating disorders in order to evade or reduce the potential harmful complications associated with it

    Kegagalan Penguasaan Bahasa Inggeris Bagi Murid Di Sekolah Luar Bandar

    No full text
    Kertas kerja ini dijalankan untuk meninjau faktor kegagalan murid tahap satu sekolah-sekolah rendah di luar bandar dalam menguasai Bahasa Inggeris. Hal ini kerana pengenalan program Common European Framework of References (CEFR) masih baharu dalam sistem pendidikan Malaysia. Program ini menuntut guru-guru dan murid untuk mencapai standard penguasaan tertentu agar selaras dengan negara-negara lain di peringkat antarabangsa. Kajian ini dijalankan menggunakan pendekatan kualitatif melalui analisis deskriptif dengan merujuk sumbersumber bacaan yang diperolehi daripada kajian terdahulu. Faktor-faktor yang mendorong kepada masalah ini di kaji secara teliti untuk mendapatkan punca kegagalan penguasaan murid di luar bandar. Kajian ini mendapati bahawa guru-guru dan murid masih belum menguasai CEFR dengan sepenuhnya. Selain itu, kajian ini juga turut menemukan bahawa program CEFR memberikan kesan yang kurang memberangsangkan kepada murid yang kurang menguasai kemahiran asas literasi Bahasa Inggeris. Oleh itu, kajian yang lebih komprehensif diperlukan di masa akan datang untuk mendapatkan hasil kajian yang lebih tepat dan mendalam terhadap permasalahan ini dan meningkatkan penguasaan murid di luar bandar khasnya

    Analysis of the effect of career planning, training and career development on employee job performance

    No full text
    Career Planning, Training and Career Development is one of several factors that affect Employee Job Performance. This paper aims to examine and analyze Career Planning, Training and Career Development influencing Employee Job Performance at PT. Pos Indonesia (Persero) Tbk Regional V Bandung. Analyzes were performed using multiple linear regression models with the help of SPSS version 16 software to analyze data. The results of hypothesis testing and analysis show that Career Planning, Training and Career Development has a significant positive effect on the Employee Job Performance of PT. Pos Indonesia (Persero) Tbk Regional V Bandung

    Tahap Kepuasan Mahasiswa Unisza Dalam MEnjalani Latihan Industri

    No full text
    Istilah latihan industri menerangkan tentang pengalaman pendek yang diperolehi tanpa melibatkan pembayaran oleh pihak industri. kajian ini dijalankan untuk mengetahui tahap kepuasan mahasiswa Universiti Sultan Zainal Abidin Kampus Gong Badak, Terengganu dalam menjalani latihan indsutri. pelbagai kemahiran yang boleh dikuasai oleh mahasiswa semasa menjalani latihan industri. oleh itu, kajian ini dijalankan untuk mengetahui tahap kepuasan mahasiswa dalam menjalani latihan industri. pengkaji melakukan kajian berbentuk kajian lapangan yang bersifat kuantitatif dan kualtatif. seramai 30 orang dipilih untuk menjadi respondan bagi kajian kajian in dan 5 orang daripada sesi protokol temubual. pengkaji menggunakan kaedah borang soal selidik bagi mengumpulkan data daripada respondan dan seterusnya menganalisis data dengan menggunakan Statistic Package For The Social Science (SPSS). Statistik inferensi Ujian-t dan korelasi digunakan bagi melihat perbezaan tahap kepuasan menjalani latihan industri berdasarkan faktor jantina dan faktor program. hasil dapatan kajian menunjukkan mahasiswa dapat mencapai tahap kepuasan yang maksimum dalam menjalani latihan industri

    Determination of Autophagic Activity Of J774a.1 Murine Macrophages Infected With Recombinant Mycobacterium Smegmatis

    No full text
    Tuberculosis (TB) remains a major worldwide health problem which causes more than 1.3 million deaths annually. The development of a new vaccine as a replacement of Bacille Calmette Guerin (BCG) or to improve its efficacy is one of the goals mooted by the World Health Organization (WHO) to control TB. Mycobacterium smegmatis (M. smegmatis) is nonpathogenic and commensal in humans, which shares many characteristics with Mycobacterium tuberculosis (M. tuberculosis). Mycobacterial vectors including M. smegmatis have been successfully used in the development of experimental vaccines against TB. In the current study, recombinant M. smegmatis expressing selected Ag85B epitopes (P1, P2 and P3) was constructed (rMs064). Autophagy play important role in delivery of the intracellular bacteria to simulate the adaptive immune response. Targeting the autophagy mechanism is a viable approach to enhance the specific immune response leading to the prevention of new infection or reactivation of latent TB. Therefore, autophagy modulation of J774A.1 murine macrophages was determined after infection with rMs064 by monitoring the LC3B-II level by flow cytometry and western blot. This experiment allows the determination of autophagy modulation as well as the autophagic flux induced by rMs064 on J774A.1 macrophages. The results of both assays showed the LC3B-II level were not significantly increased compared to uninfected macrophages. In conclusion, macrophage activation and cytokine stimulation may be required for optimal autophagy monitoring assays that can be modulated by rMs064

    Development of CBM-Fusion Protein with Oligomerization Domain (OD) from Pseudomonas aeruginosa Pseudaminidase

    No full text
    Carbohydrate binding module (CBM) from Vibrio cholerae sialidase is located at the N-terminal region which flank the central catalytic domain of the protein. It is belong to the Family 40 which recognizes single sialic acid moiety as the binding ligand. Protein usually tend to have weaker binding affinity towards its substrate, therefore a multivalent approach was carried out in order to enhance protein binding affinity via an avidity effect. In this study, DNA fragment encoding the CBM40 from V. cholerae sialidase was amplified by PCR method before cloning in E. coli BL21(DE3) using pET-22(b+) as a vector. The gene composed of 174 amino acids from an open reading frame comprising 522 bp nucleotide sequence. CBM40-fusion protein was developed by linking the second domain known as Oligomerization domain (OD) which isolate from Pseudomonas aeruginosa pseudaminidase. The domain consists of an open reading frame of 321 bp with the ability to form a trimeric protein molecule. The OD domain was amplified by PCR method with the addition of BamH1 and EcoR1 sites before ligation was performed on pET-22b(+) vector. In addition, five amino acids linker length was generated to flank in the CBM and the OD domain. Choices of fusion linkers were designed composed of flexible residues like glycine (G) and serine (S) which are flexible group of amino acids. This recombinant fusion construct was cloned into the pET-22b(+) vector and transform into E. coli BL21 (DE3) host. Positive recombinant fusion molecule was identified by colony PCR and confirmed by DNA sequencing techniques. A comprehensive characterization of the recombinant fusion proteins is currently under evaluation. This CBM-OD construct has a big potential to be developed as a therapeutics agent to combat harmful pathogens which recognize sialic acid as the binding substrate

    1,080

    full texts

    8,142

    metadata records
    Updated in last 30 days.
    UniSZA Institutional Repository
    Access Repository Dashboard
    Do you manage Open Research Online? Become a CORE Member to access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard! 👇