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Improving Accuracy of Imbalanced Clinical Data Classification Using Synthetic Minority Over-Sampling Technique
No full textImbalanced datasets typically occur in many real applications. Resampling is one of the effective solutions due to
producing a balanced class distribution. Synthetic Minority Over-sampling technique (SMOTE), an over-sampling
technique is used in this study for dealing the imbalanced dataset by add the number of instances of a minority
class. This technique is used to decrease the imbalance percentage of the dataset by generating new synthetic
samples. Thus, a balanced training dataset is produced to replace the class imbalanced . The balanced datasets were
obtained and trained with machine learning algorithms to diagnose the disease’s class. Through the experiment
findings on the real-world datasets, oral cancer dataset and erythemato-squamous diseases dataset from the UCI
machine learning datasets, an over-sampling method showed better results in clinical disease classification
The Utilization of Military Lifetime Health Record
No full textWith the growth of IT, a comprehensive electronic health record system for the Malaysian armed forces is a must.
However, because of the low success rate in the use of electronic health record systems, it is important to identify user
acceptance factors for the systems. Thus, a research model that is grounded in TAM and UTAUT is developed to
identify user adoption factors for Malaysian Armed Forces Hospital and Clinics to ensure the significant success of
Military Lifetime Health Record (MLHR) implementations. A self-administered survey technique is employed and
useful responses collected from users (military clinicians and medical personnel). The research model was then tested
using the partial least square (PLS) technique. The results of this study confirm that behavioral intention is significant
to actual usage of MLHR system by military clinician and medical personnel. Except of effort expectancy, all four ()
factors namely performance expectancy, social influence, facilitating condition and computer self-efficacy positively
affect the military clinicians and medical personnel's intention to use the MLHR system. This study confirms that
performance expectancy, social influence, facilitating condition and computer self-efficacy drive users' behavioral
intention toward MLHR system usage. Having a clear understanding of what and how these determinants influence
military clinician and medical personnel' behavioral intention is important as it can help make MLHR systems the
main source of module when it comes to the next level HIS project for MAF
Dynamical analysis of carbon concentration model due to the interaction with biomass production based on predator-prey
No full textThe high energy demands and the development of technology produce transcendent concentration of atmospheric
Carbon dioxide gas emission. Many studies have been conducted to develop a model of the carbon dioxide cycle to
understand its characters. Here, we proposed the model of the interaction between Carbon consumption due to the
biomass production. The model is currently developed to characterize the dynamical behaviour of the climate vector of
the gas to predict its stability. We simulated the Rungge-Kutta method to analyze the bifurcation and define the
Jacobian matrix to see the eigen value. The result gave the idea that the gas concentration can be controlled by
manipulating its uncertain parameters and could be a provisional prediction for several years ahead
Find the maximum clique by graph coloring using heuristic greedy
No full textGraph coloring problem is to find the minimal number of colors to color vertex of a graph in such a way that every two
vertex linked by an edge have different colors. A vertex coloring algorithm has been presented. As a result of applying
vertex coloring algorithm no two vertex are to be allocated in same color if they are adjacent in graph. In this paper,
Graph coloring used for to find maximum clique in a graph with heuristic greed
The Role of Transient Receptor Potential Cation Channel subfamily V member 4 (TRPV4) in Colorectal Cancer
No full textThe transient receptor potential cation channel subfamily V member 4 (TRPV4) is a non-selective
calcium (Ca2+)-permeable channel which is expressed in many types of tissues. In addition to its
roles in various physiological processes such as osmoregulation and mechanosensation, growing
evidence suggests that TRPV4 is also involved in several aspects of tumourigenesis. Despite the
reported roles of TRPV4 in several types of cancers, the role of TRPV4 in colorectal cancer has
not been extensively assessed. This study aimed at exploring the potential role of TRPV4 in
colorectal cancer cells. Quantitative real-time PCR analysis showed that TRPV4 mRNA levels
were lower in HT-29 colorectal cancer cells than normal colon CCD-18Co cells. In contrast,
TRPV4 mRNA was undetected in HCT-116 colorectal cancer cells. Pharmacological activation of
TRPV4 using GSK1016790A promoted the proliferation of HT-29 cells while TRPV4 inhibition
using RN 1734 decreased their proliferation, as assessed by the MTT cell proliferation assay. Cotreatment with RN 1734 attenuated GSK1016790A-induced increases in proliferation in HT-29
cells. Cell cycle analysis by flow cytometry revealed that pharmacological modulation of TRPV4
had no pronounced effect on the cell cycle progression in HT-29 cells. Analysis from the AnnexinV/PI double-staining assay demonstrated that both activation and inhibition of TRPV4 channel
could promote the death of HT-29 cells, despite at different degrees of cell death induction.
Altogether, these findings suggest divergent TRPV4 mRNA expression levels between human
colorectal cancer cells and normal colon cells. Pharmacological modulation of TRPV4 appears to
alter the proliferation of HT-29 cells and induces cell death in this cell line. TRPV4 may represent
a promising drug target for the treatment of colorectal cancer
الحركة العلمية في تهامة اليمن وأثرها في العلوم الشرعية
No full textتربز إشكالية البحث قي معرفة احلياة العلمية يف منطقة هتامة اليمن وأثرها على تطور العلوم الشرعية فيها حيث أهنا مل تنل حظها من البحث والعناية ما انلته أمثاهلا
من احلواضر اإلسلمية، حيث هتدف هذه الدراسة على معرفة مظاهر النشاط للحركة العلمية هبا وأبرز من وفد إليها من العلماء واملسامهة الفعالة يف االبداع
والتأليف يف شىت العلوم واملعارف ومعرفة املراكز العلمية هبا واملنهج املتبع هو املنهج االستقرائي واملنهج الوصفي وحتليل مظاهر النشاط العلمي ومعرفة أسباب
الركود يف التأليف واالبداع ويف النهاية توصل الباحث إىل وجود حركة علمية زاخرة ابملصنفات النادرة واليت حيتاج إليها طلب الشريعة اإلسلمية بشىت جماالهتا
يف علوم القران والتفسري والفقه واحلدي
Rukun negara as constitution’s preamble: an overview
No full textRukun Negara is the Malaysian declaration of national philosophy where it was drafted between 1970
and 1971 by National Consultative Council and had been launched on 31 August 1970 by the Yang diPertuan Agong at that time. The aims are to realise Malaysia’s ambitions towards enhancing unity
among the people; safeguarding the spirit of democracy; establishing a just society; maintaining
a liberal approach in addressing diversity; and creating a progressive and technologically
advanced society. In fulfilling the above ideals, the Rukun Negara underlines five core principles: Belief
in God; Loyalty to the King and Country; Supremacy of the Constitution; Rule of Law; and Good
Behaviour and Morality. The issue to be discussed in this paper is whether the inclusion of five core
principles Rukun Negara as Federal Constitution’s preamble will strengthen and given greater effect to
Rukun Negara as it will have the status of law and consequently undermine the constitutional
supremacy. The methodology used in this paper was qualitative and content legal analysis method. It
is clear that Federal Constitution is already complete and comprehensive. Though there are some
vagueness left in the Constitution itself, it still is open for interpretations without the need of including
Rukun Negara as a preambl
The Value of Discovering the Efficient Surface Anatomy Teaching Method
No full textIntroduction: Surface anatomy is the study of the external features of the human body meaning not only it is used to identify structures beneath the skin but it enables the students to perform onical examinations, intenentional procedures and interprete radiological images. Since Mere is scarce evidence on the best teaching method for surface anatomy. the am of this study was to justly the need in seeking a pnme approach in teaching surface anatomy.
Materials and Methods. A literature search on the importance of leammg surface anatomy was performed using Gocgle Scholar and PuhMed databaSes
Results and Discussion: The declining surface anatomy knowledge in modern curriculum has resulted in procedural at surgical avers. Successful teaming of surface anatomy requres a balance between comprehension and Insuakzation Learners believed Mat mriovative approaches such as body paintmg, living anatomy model, virtual human dissector and digital X-ray are instrumental in boosting their surface anatomy skills. A study done showed an increase in undergraduate students' understanding of anatomical structures after introduction to ultrasound training as it promoted students procedural skill and their confidence level on performing clirucal procedures. The techrique of drawing anatomical structures that requires extra focus of concentration. lateral thinking and knowledge transfer skills could also result in higher understanding of the subject learned Indeed, integration of surface anatomy IA a practical course has resulted in improved knowledge, understandmg and confidence level in clinical practice.
Conclusion: Surface anatomy is still relevant to produce sale doctors. Hence, roovation in surface anatomy teaching is pertinent for effective learning and contribute to competent clinical students and doctor