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BRITISH AIRWAYS’TEN NIKE’A: REKLAMDA YÜZ İMGESİ VE BİR DÜNYA YAPMAK
Get PDFBritish Airways'in 1989 tarihli Globe (Face) reklamı (HudsonFilmLtd, 2012) ve Nike’ın 2018 tarihli Dream Crazy reklamlarını (Franck, 2018; Kemp, 2022) örnek olarak seçerek bu reklamlar üzerinden bir anlatı analizi ve söylem çözümlemesi gerçekleştiren bu çalışma; reklamda yüz imgesinin ardına düşen estetik kaygılara politik, ekonomik, sosyal ve kültürel olarak eşlik eden anlamları ortaya koymaya odaklanmıştır. Bu iki tarihi kampanyada yüz, Goodman’dan (1978) yola çıkarak söylersek, bir dünya yapan yüz; birleştiren ve ayrıştıran, inşa eden ve bozan, sınırlardan taşarak özgürleşen ama aynı zamanda yersizyurtsuzlaşandır. Deleuze ve Guattari'nin yüzsellik ile ilişkili olarak bahsettiği beyaz duvar ve siyah delikler (Holland, 2013, s. 92); mal, hizmet ve paranın dünya üzerinde hızla dolaşımını kolaylaştıran ulaşım sektörünü temsilen British Airways markasının reklam anlatısı üzerinden değerlendirilebilir. Bu reklamda uçsuz bucaksız bir zemin üzerinde, doğanın içinde tek tek organlardan -ağız, kulak, burun- oluştuğunu yukarıdan geniş açı ile gördüğümüz, idaresi yukarıdan bakan bir göz ve güç gerektiren ancak tamamlandığında gülümser ifadesi ve göz kırpışıyla tekinsiz, iki boyutlu, adeta despotik bir yüz doğar. Black Lives Matters hareketini ardına alan Colin Kaepernick de Nike açıkhava reklamında, tek başına yüzüyle adeta ölüme meydan okuyan, siyahi bir Amerikan vatandaşı olarak, ifadesiz bir şekilde tam karşıya bakar. Bu bağlamda marka “öteki”ni sadece yüzü açıkta kalacak biçimde eritir, Miyazaki’nin No-Face karakteri gibi sadece yüzden kurulu, her şeyi yutsa da yüzü sabit kalan bir canlıya, işler halde bir makineye dönüştürür. Sonuç olarak her iki kampanya, birbirine yüz imgesi üzerinden teğet geçip farklı yörüngeleri izleyerek zamanın ruhuna uygun bir anlamlar bütünü oluşturma ve satış görevlerini başarıyla tamamlarlar
Clinical Effects of Additional Platelet-Rich Plasma Application to Exercise Therapy in Patients with Subacromial Impingement Syndrome: A Double-Blind Randomized Controlled Trial
Get PDFBackground: Exercise therapy (ET) is the main and initial treatment modality for treating subacromial impingement syndrome (SIS). The isolated or combined use of platelet-rich plasma (PRP) applications in treating SIS is increasing and promising. A comparison was made on the effectiveness of ET alone and in combination with PRP on pain, functionality, and quality of life (QoL) in patients with SIS. Purposes/Hypothesis: The purposes of this study were to (1) investigate the possible positive effects of PRP injections combined with ET in treating SIS on pain, functionality, and QoL and (2) propose an alternative treatment protocol. It was hypothesized that the group receiving PRP applications in addition to ET would have a better QoL due to less pain and higher functionality 6 months after treatment. Study Design: Randomized controlled trial; Level of evidence, 2. Methods: Volunteer patients diagnosed with SIS were included based on history and physical examination findings. All participants underwent magnetic resonance imaging to confirm the diagnosis and exclude possible accompanying pathologies. The patients were randomly divided into 2 groups. The first group underwent ET at home for 8 weeks (ET group), and the second group received the same ET program and an additional 2 PRP injections, at the beginning of the study and the end of the fourth week (PRP group). Patients were evaluated initially and 6 months after the treatment using the visual analog scale (VAS) for pain score, Constant-Murley Score (CMS), and the 36-Item Short Form Health Survey (SF-36). The Kolmogorov-Smirnov test determined the conformity of the data to a normal distribution, chi-square analysis was used to compare categorical variables between groups, and the Mann-Whitney U test was used to compare continuous and intergroup variables. Intragroup changes before and after treatment were evaluated with the Wilcoxon signed-rank test. P .05) at 6 months. Conclusion: Our study showed that both isolated ET and additional PRP application to ET are effective methods in SIS treatment regarding pain, function, and QoL. Combining ET with PRP was superior in reducing pain and improving abduction degree and strength.The authors acknowledge Associate Professor Altu Duramaz for his critical review of this work
METAVERSE AND CHATGPT: INNOVATIVE LEARNING EXPERIENCES IN EDUCATION AND INTERACTIVE STRATEGIES IN MARKETING
Get PDFPurpose- This study investigates the potential of ChatGPT and the metaverse as transformative digital technologies, with a focus on their applications and benefits within education and marketing sectors. It aims to understand how ChatGPT, as an AI language model, can enhance interactivity in virtual environments, particularly within the metaverse. Methodology- The research involves an in-depth literature review on digital technologies driving the metaverse, specifically examining ChatGPT's integration and its impact on user engagement in virtual spaces. The study also reviews current applications and explores potential roles for ChatGPT in marketing, branding, and educational contexts within the metaverse. Findings- Results indicate that ChatGPT can significantly enhance user interaction in the metaverse by enabling more personalized, responsive virtual assistants. In education and marketing, this integration facilitates immersive experiences, providing tailored support, information, and engagement opportunities in a virtual format. Conclusion- The combined application of ChatGPT and the metaverse holds significant promise, presenting opportunities for enhanced digital interaction and personalized experiences across industries. However, limitations such as technological constraints and privacy concerns require ongoing attention to maximize these benefits effectively
Away from home and excluded from local solidarity networks: Undocumented Afghan migrant men in Istanbul
Get PDFThe paper presents a study on the solidarity networks of undocumented Afghan male migrants in Istanbul. The research was conducted between August 2015 and June 2020 in the migrant districts of Beykoz, Zeytinburnu and Fatih. The study found that Afghan migrants are excluded from existing local solidarity networks and instead form their own networks as a survival strategy. The study posits that there are three primary solidarity networks knitted by locals, which are 'family', 'hometown' and 'neighbourhood'. We argue that the foundation of the solidarity networks among the locals is their shared language(s), mutual recognition, shared socio-historical background and unofficial trust, making it difficult for newcomers to become a part of this solidarity. Afghan migrants are unable to access these networks, which aggravates their social exclusion. They use their social exclusion as a survival strategy and continue with their migration aspirations.Raoul Wallenberg Institute 2019 RWI-Human Rights Research GrantThe last stage of this research in Beykoz, Zeytinburnu and Fatih districts of Istanbul is based on the research project 'The Role of Call Shops in Istanbul in The Transnational Migration Experiences of Unaccompanied Afghan Boys and the Gender Regime in Call Shops' funded by Raoul Wallenberg Institute 2019 RWI-Human Rights Research Grant, carried out by Mehmet Bozok and Nihan Bozok
İnsanın düşüşü: Kazuo Ishıguro'nun Beni Asla Bırakma ve Klara ile Güneş romanları üzerine karşılaştırmalı bir çalışma
Get PDFBu tez, Japon-İngiliz romancı Kazuo Ishiguro tarafından yazılan Beni Asla Bırakma ve Klara ile Güneş adlı iki romanı posthümanist bir bakış açısıyla karşılaştırmaktadır. Posthümanizm olarak bilinen bir düşünce okulu, hümanizmin varsayımlarını sorgulamaktadır. Hümanist felsefeye göre insanlar diğer canlılardan üstündür. Ancak posthümanizm buna meydan okur. İnsanlar ve insan olmayan varlıklar arasındaki ilişkinin hiyerarşik olmadığını ileri sürer. Özellikle teknolojik gelişmeler ışığında, hümanizmin temellerinden şüphe duymak giderek yaygınlaşmaktadır. Ishiguro her iki romanında da posthümanist ortamlar inşa eder. Beni Asla Bırakma'da organlarını almak için yaratılan klonlar vardır. Klara ile Güneş'te ise çocuklara eşlik etmesi için üretilen yapay arkadaşlar mevcuttur. Bütün olarak düşünüldüğünde her iki roman da posthümanist edebiyatın seçkin örneklerindendir. Ishiguro'nun Beni Asla Bırakma'yı yazmasından bu yana dünya daha posthümanist bir hal almıştır ki bu da Klara ile Güneş'in Beni Asla Bırakma'dan daha posthümanist olduğunu savunan bu tezle tutarlıdır. Klara ile Güneş, yapay zekayı içermesi, insan olmayan varlıkların haklarını sorgulaması, insanlar ve insan olmayan varlıklar arasındaki etkileşimleri ele alması ve güncel olaylarla örtüşmesi nedeniyle Beni Asla Bırakma'dan daha posthümanisttir.This thesis compares two novels, Never Let Me Go and Klara and the Sun, written by British novelist Kazuo Ishiguro from a posthumanist viewpoint. A school of thought known as posthumanism questions the assumptions of humanism. According to humanist philosophy, humans are superior to other living things. Posthumanism, however, challenges this. It asserts that the connection between humans and nonhuman entities is not hierarchical. It is becoming increasingly common to doubt the fundamentals of humanism, particularly in light of technological advancements. Ishiguro constructs posthumanist settings in each of his works. There are clones created in Never Let Me Go in order to take their organs. There are artificial friends produced to accompany children in Klara and the Sun. When the whole thing is considered, both novels are outstanding examples of posthumanist literature. The world has become more posthumanist since Ishiguro wrote Never Let Me Go, which is consistent with this thesis, which holds that Klara and the Sun is more posthumanist than Never Let Me Go. Klara and the Sun is more posthumanist than Never Let Me Go since it incorporates artificial intelligence, questions the rights of nonhuman entities, addresses interactions between humans and nonhuman entities, and keeps up with contemporary events
Exploring Druggable Binding Sites on the Class A GPCRs Using the Residue Interaction Network and Site Identification by Ligand Competitive Saturation
Get PDFG protein-coupled receptors (GPCRs) play a central role in cellular signaling and are linked to many diseases. Accordingly, computational methods to explore potential allosteric sites for this class of proteins to facilitate the identification of potential modulators are needed. Importantly, the availability of rich structural data providing the locations of the orthosteric ligands and allosteric modulators targeting different GPCRs allows for the validation of approaches to identify new allosteric binding sites. Here, we validate the combination of two computational techniques, the residue interaction network (RIN) model and the site identification by ligand competitive saturation (SILCS) method, to predict putative allosteric binding sites of class A GPCRs. RIN analysis identifies hub residues that mediate allosteric signaling within a receptor and have a high capacity to alter receptor dynamics upon ligand binding. The known orthosteric (and allosteric) binding sites of 18 distinct class A GPCRs were successfully predicted by RIN through a dataset of 105 crystal structures (91 ligand-bound, 14 unbound) with up to 77.8% (76.9%) sensitivity, 92.5% (95.3%) specificity, 51.9% (50%) precision, and 86.2% (92.4%) accuracy based on the experimental and theoretical binding site data. Moreover, graph spectral analysis of the residue networks revealed that the proposed sites were located at the interfaces of highly interconnected residue clusters with a high ability to coordinate the functional dynamics. Then, we employed the SILCS-Hotspots method to assess the druggability of the novel sites predicted for 7 distinct class A GPCRs that are critical for a variety of diseases. While the known orthosteric and allosteric binding sites are successfully explored by our approach, numerous putative allosteric sites with the potential to bind drug-like molecules are proposed. The computational approach presented here promises to be a highly effective tool to predict putative allosteric sites of GPCRs to facilitate the design of effective modulators.National Center for High Performance Computing of Turkey (UHeM); University of Maryland Computer-Aided Drug Design Center [2211/C]; TUBITAK National Ph.D. Scholarship Program in the Priority Fields in Science and Technology [2211/C]; Istanbul Technical University Scientific Project [THD-2024-45545, TDK-2020-42717]; NIH [R35 GM131710]; TUBITAK ULAKBIM High Performance and Grid Computing Center (TRUBA)Computing resources used in this work were provided by the National Center for High Performance Computing of Turkey (UHeM), the TUBITAK ULAKBIM High Performance and Grid Computing Center (TRUBA), and the University of Maryland Computer-Aided Drug Design Center. M.Y. thanks to the TUBITAK National Ph.D. Scholarship Program in the Priority Fields in Science and Technology (2211/C). O.K. acknowledges Istanbul Technical University Scientific Project THD-2024-45545 and TDK-2020-42717 and A.D.M., Jr., acknowledges support from the NIH (R35 GM131710)
Covid-19 Pandemisi Sürecinde Sağlık İşgücü Politikası ve Yönetimi: İş Tatmini ve Örgütsel Güven1
Get PDFIn the study, the aim is to evaluate the relationship between Covid-19 preparedness organizational trust and job satisfaction, which are key interventions in health workforce policy and management during the Covid-19 pandemic as recommended by WHO and ILO. Additionally, the study aims to provide resources for the development of more efficient and effective intervention methods for future pandemics. It is the first study to investigate the relationship between the level of job satisfaction among health-care workers and the level of organizational trust in Covid-19 readiness. The research is a descriptive-cross-sectional study. Questionnaires were administered to 400 healthcare workers who were involved in various tasks during the Covid-19 pandemic and agreed to participate in the study. The data collection form included questions related to sociodemographic characteristics and occupation, as well as the Minnesota Job Satisfaction Scale and the Covid-19 Readiness Organi-zational Trust Scale. The internal consistency of the scales was examined by calculating correlation coefficients and Cronbach’s alpha values. Principal Components Analysis was performed for factor analysis. The adequacy of the sample size for the factor was evaluated using the KMO test and the suitability of the scale items for factor analysis was assessed using Bartlett’s Test of Sphericity. Analyses were conducted to determine the sub-dimensions and items of the scales. It has been observed that job satisfaction is positive with confidence in Covid-19 preparation, job satisfaction of those who trust the institution and employees increases positively, and organizational trust of those who are satisfied with the quality of the job and the working environment are positively affected. © 2024, Ebru Bagci. All rights reserved
Classification of digital evidence in criminal procedure law and emerging problems
Get PDFDijital dünyada yaşanan gelişmeler modern insanın hayatını büyük ölçüde kolaylaştırmaktadır. Günümüzde gelinen noktada, bankacılık işlemlerinden alışverişe, iletişimden eğitime kadar birçok alanda dijitalleşmenin giderek artan bir ivme ile hayata entegre olduğunu görmekteyiz. Özellikle dijital dönüşümün hızı düşünüldüğünde bu konuda etik ve hukuki çalışmaların ve düzenlemelerin de bu gelişmelere paralel hızda revize edilmesi ihtiyacı doğmaktadır. Dijitalleşmenin günlük hayat akışı içerisine bu derece dahil olması sebebiyle, modern insanın her gün defalarca kez farklı alanlarda bıraktığı "dijital iz" söz konusudur. Bu dijital dönüşümü hukuken göz ardı etmek mümkün olmamakla birlikte, ceza yargılamalarında temel arayışın maddi gerçeğe ulaşmak olduğu açıktır. Ceza muhakemesi hukuku açısından hukuka aykırılık teşkil etmeyen ve hukuka uygun yollarla elde edilmiş her verinin delil olma niteliği mevcuttur. Dolayısıyla hayatın her alanının giderek dijitale evrilmesi ve insanın bıraktığı dijital izler göz önüne alındığı takdirde, dijital verilerin delil olarak kullanılması kaçınılmaz hale gelmiştir. Türk hukukunda dijital delillerin kullanımıyla ilgili açık bir yasal düzenleme olmaması ve dijital verilerin yapıları gereği manipülasyona açık olmaları da ispat konusunda şüpheye sebep olabilecek durumlar doğurmaktadır. Çalışmamızda öncelikle ceza muhakemesi hukukunda ispat ve delillerin özellikleri incelenecek, ardından delil türlerinin neler olduğu ve dijital delillere ilişkin bilgiler ele alınacaktır. Çalışmanın üçüncü bölümünde, Türk Ceza Yargılaması Hukuku'nda delillerin değerlendirilmesi ve son bölümünde ise, Türk Ceza Yargılamasında dijital delillerin değerlendirilmesi hususu ele alınacaktır.Developments in the digital world greatly facilitate the lives of modern people. Today, we see that digitalization is being integrated into life with increasing momentum in many areas, from banking transactions to shopping, from communication to education. Especially considering the speed of digital transformation, there is a need to revise ethical and legal studies and regulations in parallel with these developments. Since digitalization is so integrated into the flow of daily life, there is a "digital trace" left by modern people in different areas many times every day. Although it is not possible to ignore this digital transformation legally, it is clear that the main quest in criminal trials is to reach the material truth. In terms of criminal procedure law, any data that does not constitute a violation of the law and is obtained by lawful means has the quality of being evidence. Therefore, considering that every aspect of life is gradually evolving into digital and the digital traces left by humans, it has become inevitable to use digital data as evidence. The lack of a clear legal regulation regarding the use of digital evidence in Turkish law and the fact that digital data are open to manipulation due to their nature also create situations that may cause doubts about proof. In our study, firstly, the characteristics of proof and evidence in criminal procedure law will be examined, then the types of evidence and information on digital evidence will be discussed. In the third part of the study, the evaluation of evidence in Turkish Criminal Procedure Law and in the last part, the evaluation of digital evidence in Turkish Criminal Procedure will be discussed
Effects of organic acid treatments combined with modified atmosphere packaging on survival of pathogens and quality parameters of meatballs
Get PDFThe present work was conducted to determine the effects of organic acids (1 and 2% of sodium lactate, 0.5% potassium sorbate, 0.5% sodium citrate, and 1% sodium acetate) combined with ambient air and modified atmosphere packaging (HiOx: 80:20:0/O-2:CO2:N-2; CO: 0.4:30:69.60/CO:CO2:N-2) on the quality parameters and shelflife of meatballs, and to evaluate the survival of Salmonella Typhimurium and Listeria monocytogenes in inoculated meatballs stored at 4 degrees C for 15 d. Results indicated that the organic acid combinations delayed the microbial growth, and improved the shelf-life of meatballs. Lipid oxidation was retarded with organic acid treatments, and the meatballs in CO -MAP did not exceed the spoilage level during the storage period. A difference of 12 log and 2 - 3 log units of S. Typhimurium and L. monocytogenes counts were recorded between the untreated and organic acids treated meatballs, respectively, with effectiveness in HiOx and CO -MAP. Enhancement in colour and textural properties was detected in the meatballs treated with combined organic acids and 2% sodium lactate. Moreover, the overall acceptability of 2% sodium lactate treated meatballs was rated more palatable by the panellists at the end of the storage. In conclusion, organic acid treatments combined with modified atmosphere packaging can maintain the storage properties of meatballs without influencing the sensory characteristics during refrigerated storage.Scientific Research Projects Coordination Unit of Istanbul University-Cerrahpasa [15423, 15427]The present work was financially supported by the Scientific Research Projects Coordination Unit of Istanbul University-Cerrahpasa (project no.: 15423 and 15427)
Aleksitiminin Kaygı Düzeyleri ve Mizah Tarzları İle İlişkisinin İncelenmesi
Get PDFObjective: The objective of this study was to investigate the relationships between alexithymia, humor styles and anxiety levels and the nature of these relationships. Method: The sample of the study consisted of 254 students from ….. University. In the context of the research, ‘’Toronto Alexithymia Scale’’ (TAS-26) was used to measure alexithymia levels, ‘’Humor Styles Questionnaire” (HSQ) was used to measure humor styles, ‘’State and Trait Anxiety Inventory’’ (STAI) was USED to measure anxiety levels. In addition, the Sociodemographic Data Form, which was prepared by the researchers and included various sociodemographic variables assumed to be associated with these variables, was used. Results: Research findings indicate that different dimensions of alexithymia are associated with both state and trait anxiety. Alexithymic features are negatively associated with the positive use of humor and positively associated with negative use. On the other hand, positive use of humor is negatively correlated with anxiety levels. In addition, alexithymia, humor styles and anxiety levels seem to be related to sociodemographic variables such as age, gender, education levels of parents, parental working status, psychiatric diagnosis in the participant and his/her caregiver, and history of physical illness in the participant. Alexithymia, different dimensions of alexithymia and anxiety levels predict humor. Conclusion: The results of this study indicate that the variables of alexithymia, anxiety levels and humor styles are correlated with each other and with various sociodemographic variables in different dimensions. Since the sample of the study consists of students from a private university, it is not possible to generalize the results to the student population representing this age group.Amaç: Bu çalışmanın amacı aleksitimi, kaygı düzeyleri ve mizah tarzları arasındaki ilişkinin ve bu ilişkinin niteliğinin incelenmesidir. Yöntem: Araştırmanın örneklemini ……. Üniversitesi öğrencilerinden 254 kişi oluşturmuştur. Araştırma bağlamında aleksitimi düzeylerini ölçmek amacıyla ‘’Toronto Aleksitimi Ölçeği’’ (TAÖ-26), mizah tarzlarını ölçmek amacıyla ‘’Mizah Tarzları Ölçeği’’ (MTÖ), kaygı düzeylerini ölçmek amacıyla ‘’Durumluk ve Sürekli Kaygı Envanteri’’ (DSKE) kullanılmıştır. Ayrıca araştırmacılar tarafından hazırlanan ve bu değişkenlerle ilişkili olduğu varsayılan çeşitli sosyodemografik değişkenleri içeren Sosyodemografik Veri Formu kullanılmıştır. Bulgular: Araştırma bulguları aleksitiminin farklı boyutlarının hem durumluk hem de sürekli kaygı ile ilişkili olduğuna işaret etmektedir. Aleksitimik özellikler mizahın olumlu biçimde kullanımı ile negatif; olumsuz biçimde kullanımı ile pozitif yönde ilişkilidir. Öte yandan, mizahın olumlu kullanımı, kaygı düzeyleriyle negatif yönde ilişkilidir. Ayrıca aleksitimi, kaygı düzeyleri ve mizah tarzları değişkenleri yaş, cinsiyet, anne babanın eğitim düzeyleri, anne babanın çalışıyor olup olmaması, katılımcının ve bakım verenlerin psikiyatrik tanı alıp almamış olması, katılımcının bedensel hastalık öyküsünün olup olmaması gibi sosyodemografik değişkenlerle de ilişkili görünmektedir. Aleksitimi, aleksitiminin farklı boyutları ile kaygı düzeyleri mizah tarzlarını yordamaktadır. Sonuç: Bu çalışmanın sonuçları aleksitimi, kaygı düzeyleri ve mizah tarzları değişkenlerinin birbirleri ile ve çeşitli sosyodemografik değişkenlerle farklı boyutlarda ilişkili olduğuna işaret etmektedir. Çalışmanın örneklemini özel bir üniversitenin öğrencilerinin oluşturması dolayısıyla sonuçları bu yaş grubunu temsil eden öğrenci popülasyonuna genellenemez