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In Salt Lake City, Everyone and Everything is Queer*
No full textSamuel Autman’s “In Salt Lake City, Everyone and Everything is Queer*” is an extraordinary insight into his time in Salt Lake city on the education beat
Investigating Neurite Outgrowth Influenced by Breast Cancer Progression Using In Vitro Models of Collagen I Hydrogels
Get PDFThrough the use of vitro modeling of tumor progression, using collagen I hydrogels and progressing cell lines, a demonstration of the interactions between breast cancer cells and nerve cells can be investigated. With these models, our goal is to compare the measurement of outgrowth of nerve cells through the use of supplemented NGF and co cultures of breast cancer cells. Human MCF-CA1a.cl1, -AneoT, and -10A, adipose-derived stem cells (ASCs), and rat PC-12 cells, were all passaged from 2D cultures and cultured in a collagen I hydrogen at a cell density of 250,000 cells/ml of media. Collagen hydrogels were then made from a warm mammalian cell procedure. PC-12 cells were seeded on top for four hours after gels were made then media was added. NGF for NGF supplemented cultures was added on day 0 and after 72 hours was removed through a media change. Gels were fixed after 8 days of culture. Immunofluorescence staining was used with neurofilament and beta III tubulin being used to identify perineural invasion. DAPI was used as a nuclear counterstain. Immunofluorescence imaging showed that there was zero outgrowth when no NGF was added. However, outgrowth did appear when NGF was added as well as in all MCF media cultures. Nonetheless, there was no significant difference in the percentage of PC-12s with outgrowth per field of view. The AneoT media had the highest average percentage of PC-12s with outgrowth (51.5%), as well as the highest average length of outgrowth (37.04 µm). Measuring the neurite length, all PC-12 cultures treated with MCF media only were significantly higher than no NGF treatment. By comparing the length of outgrowth and the percentage of outgrowth, we found that AneoT cells had a significant influence on the length of outgrowth.https://scholarship.depauw.edu/srfposters/1157/thumbnail.jp
A quotient of Fomin-Kirillov algebra and Q-Lucas polynomial
Get PDFWe introduce a quotient of the Fomin-Kirillov algebra F K(n) denoted by F KCn (n), over the ideal generated by the edges of a complete graph on n vertices that are missing in the n-cycle graph Cn. In this quotient algebra, we establish a one-to-one correspondence between the basis elements and the set of matchings in an n-cycle graph. We prove that the Hilbert series of F KCn (n) corresponds to the q-Lucas polynomials, and the dimension of this quotient algebra is equal to the Lucas number Ln. We also find the character map of this quotient algebra over the Dihedral group Dn
Actin Depolymerization by β-Amino Alcohol in Breast Cancer Cells
No full textAs breast cancer is heterogeneous, there is a strong need to diversify current treatment and discover more options for advanced breast cancer. Pyrrolidinyl-substituted β-amino alcohol (pyrrolidine for short) is a drug synthesized from Hansen Lab at DePauw that can kill MCF-7 breast cancer cells. Previously, we have seen MCF-7 struggling to migrate in scratch assay, and maintain proper cell shape in actin fluorescent staining. By combining both tests in one experiment, we attempted to observe how their actin structure changes during migration. In this research, we have narrowed down the mechanism of action of pyrrolidine to be actin depolymerization. This effect disrupts the formation of lamellipodia and stress fibers, which prevents MCF-7 cells from migrating and surviving.https://scholarship.depauw.edu/srfposters/1147/thumbnail.jp
What Meney Meney Mothers There Are With Whom I Would Not Trade: Scanning & Transcribing the 1916 Diary of Frederika Heinen
Get PDFLaney Collier scanned and transcribed a 1916 diary owned by Caroline Gilson, passed down from her mother, Arlene Abel Luchsinger. The diary was kept by Caroline’s great-great grandmother, Frederika Heinen. Frederika recorded her daily activities, the weather, community events, household activities, and family member interactions. Laney and Caroline created a manuscript transcription style guide and appendices to aid in the reading of the diary. Diary research included women and diary-keeping practices, personal communication, Kansas history, and history of Clay County/Green, Kansas. This diary serves as a historical artifact that tells the story of a family and community in 1916.https://scholarship.depauw.edu/srfposters/1141/thumbnail.jp
A Community-Level Investigation of Heavy Metal Pollution in Street Sediments from Terre Haute, Indiana
No full textUrban environments contain environmental legacy issues that can have long-term negative public health consequences. Investigating these legacy issues can help constrain potential sources and their impact on communities. This study focuses on street sediment found in Terre Haute, Indiana, a city with an extensive history of coal-fired power production, high-traffic volumes, steel manufacturing, and Pb-based paint usage. This research specifically focuses on Terre Haute’s Sheridan Park community. Six bulk street sediment samples were analyzed by pXRF at DePauw University. This analysis revealed elevated concentrations of Pb (22-152 ppm), As (8-15 ppm), Cu (35-237 ppm), and Zn (149-634 ppm) in all six samples. Street samples collected near automotive buildings had the highest concentrations of heavy metals, with some concentrations seven times higher than background concentrations reported for natural soils in the area. Particle types found within the street sediment were identified using a standard stereomicroscope. This revealed four main categories: geogenic sediments, organic matter, anthropogenic debris (e.g., plastic), and metal particles. A more detailed investigation of the particle types was completed using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). This analysis revealed Fe-rich spheres, silica-rich micro-beads, and other minor heavy metal-bearing particles. This study confirms the presence of heavy metal pollution within this community. Present-day sources of these metals include the automotive industry (e.g., mechanic shops) and vehicle transportation. The Fe-rich spheres may be a byproduct of past steel manufacturing and coal-combustion within the city.https://scholarship.depauw.edu/srfposters/1162/thumbnail.jp
Real Men Don\u27t Draft Women : How Housewives Turned America Right
Get PDFThis paper analyzes the grassroots conservative movement of the 1970s in America, focusing on the significant, yet often overlooked, contributions of women in the fight against the Equal Rights Amendment (ERA). It explores how women utilized media, community outreach, and rhetoric to mobilize support for traditional family values and opposition to the ERA, drawing connections to earlier female-led movements like the Women of the Ku Klux Klan and anti-communism. The paper details strategies such as door-to-door campaigning, the use of pamphlets, community coffees , and the influence of church groups, and emphasizes the lasting impact of these methods on contemporary American politics and the rise of the tradwife movement
Persona-Based and Scenario-Based Design of Virtual and Physical Companion Robots with Varied Kawaii (Cute) Attributes
No full textIn recent years, concerns about anxiety and other mental health issues in university students have been widely reported. Some college campuses have seen increased student requests to bring emotional support animals to campus, although these animals are hard to care for in shared living spaces that are common in college settings. This paper reports on a project that seeks to gain a deeper understanding of the role that kawaii (Japanese cuteness) plays in fostering positive human response to, and acceptance of, companion robots for use by college students. In the long term, this may lead to an understanding of techniques for designing companion robots that assist with student mental health. Specifically, in this paper, we report on a persona-driven and scenario-driven cross-cultural design of two kawaii companion robots and two non-kawaii companion robots. After describing the design process and presenting the companion robot designs, the paper reports on a user study that investigates and compares the desirability of the companion robots based on their level of kawaii. After reading a persona and scenario that provided the context for the design, the study participants viewed videos of the companion robots and answered survey questions regarding the designs. Additionally, participant facial expressions were recorded by iMotions software while the participants viewed videos of the companion robots
Zero-A Game
No full textZero-A Game is a 2D platformer developed using the Java programming language. The game allows players to choose from various character classes with unique abilities to navigate challenging levels and defeat enemies. Core gameplay includes movement, jumping, and combat, with all objects adhering to realistic gravity mechanics. Players can select a character class that suits their playstyle, such as the Fighter class, equipped with a short-range sword. As players progress, they encounter increasingly difficult enemies and more complex obstacles designed to test their skills. The game focuses on delivering an engaging and dynamic experience by continually introducing new challenges, allowing players to master advanced combinations of attacks and abilities. Zero-A Game also plans to incorporate additional features such as sound effects, and background music to create an immersive gaming experience . Nan Lin Wah Sin Htoo The Burmese Recipe App is an AI-driven platform designed to introduce global audiences to Burmese cuisine. This app provides culturally authentic recipes based on users\u27 preferences, dietary restrictions, allergies, and available ingredients. It also helps users manage their kitchen pantries by tracking ingredient availability and expiration dates, while offering suggestions for meals to reduce food waste. The app includes step-by-step instructions, video tutorials, and interactive visuals, making the cooking process accessible to both beginners and experts. Users can also contribute their recipes by uploading on the recipe page for an increased community engagement. The project involves a full-stack development using Node.js, Express, MongoDB, and React.js, with AI algorithms for recommendation systems. The app will initially target users who have a strong interest in Southeast Asian cuisine, particularly Burmese, to celebrate and preserve the rich culinary traditions of Myanmar