e-space at Manchester Metropolitan University

Manchester Metropolitan University

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    36750 research outputs found

    Recommendations for adapting an online mindfulness program for people living with spinal cord injury: results from a pilot online survey with an integrated knowledge translation approach

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    Purpose To determine the implementation considerations for an online mindfulness-based intervention (MBI) tailored to individuals with spinal cord injury (SCI) and determine whether the identified preferences vary by demographic and clinical characteristics. Materials and methods This study was a cross-sectional, online survey using an integrated knowledge translation (iKT) approach. Adults with SCI across Canada and the United States participated in this study. Participants stated their preferences and importance of different aspects of the program (e.g. delivery format, session structure). The survey content was informed by an earlier qualitative study and the Template for Intervention Description and Replication (TIDieR) framework. Results 361 adults with SCI (225 males, mean age 36 (SD 8.61)) completed the survey. Prerecorded webinars were the most preferred format for an online MBI. The preferred duration and frequency of the program were 6–8 weeks and 2 sessions per week, respectively. The preferred session length was 30–45 min. Participants preferred having the program be introduced during inpatient SCI rehabilitation. Conclusions This study identified the preferred adaptations for an online MBI for individuals with SCI in Canada and the United States. Survey results will inform the development and implementation of a tailored online MBI that is relevant and meaningful to individuals with SCI. IMPLICATIONS FOR REHABILITATION Online MBIs may reduce psychological distress and improve symptom burden that individuals with SCI commonly experience post-injury. Introducing online MBIs during inpatient SCI rehabilitation could provide better support for individuals with SCI post-injury. Tailoring online MBIs based on the insights of this study, which are rooted in the experiences of individuals with SCI can increase the clinical utility of mindfulness in this population

    Why the UK Fashion Industry Should Be Written in to the New Industrial Strategy

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    A repositioning: Why the UK fashion industry should be included in the new industrial strategy. In 2020 I published Investigating Creative Processes and Pedagogy in the UK: Fashion Thinking proposing a new generation of designers was needed within the UK fashion industry with a combined skill set of designer-led innovation, a critical approach to new technology and an understanding of new engineering, digital and scientific paradigms. As a repositioning of that paper combined with recent geopolitical events, I propose fashion should have been a major part of and specifically named in the new industrial strategy document and the Creative Industries Sector Plan recently published by the Labour Government. Briefly I explore why the fashion sector should be fully recognized as the income generator it can be when linked to a reshoring and local manufacturing agenda through the industrial strategy and with reference to several Future Fashion Factory funded projects as case studies. My focus in this paper is micro and SME high-value, low-volume designer/manufacturer businesses drawing on the large number of small businesses that emerge from design schools in the UK. The UK could lead the way in developing a new paradigm for high-value fashion manufacture, engaging with a broad ecosystem of influences from sports to space

    Neuroimaging and Pathology Biomarkers in Parkinson’s Disease and Parkinsonism

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    The “Neuroimaging and Pathology Biomarkers in Parkinson’s Disease” course held on 12–13 September 2025 in Milan, Italy, convened an international faculty to review state-of-the-art biomarkers spanning neurotransmitter dysfunction, protein pathology and clinical translation. Here, we synthesize the four themed sessions and highlights convergent messages for diagnosis, stratification and trial design. The first session focused on neuroimaging markers of neurotransmitter dysfunction, highlighting how positron emission tomography (PET), single photon emission computed tomography (SPECT), and magnetic resonance imaging (MRI) provided complementary insights into dopaminergic, noradrenergic, cholinergic and serotonergic dysfunction. The second session addressed in vivo imaging of protein pathology, presenting recent advances in PET ligands targeting α-synuclein, progress in four-repeat tau imaging for progressive supranuclear palsy and corticobasal syndromes, and the prognostic relevance of amyloid imaging in the context of mixed pathologies. Imaging of neuroinflammation captures inflammatory processes in vivo and helps study pathophysiological effects. The third session bridged pathology and disease mechanisms, covering the biology of α-synuclein and emerging therapeutic strategies, the clinical potential of seed amplification assays and skin biopsy, the impact of co-pathologies on disease expression, and the “brain-first” versus “body-first” model of pathological spread. Finally, the fourth session addressed disease progression and clinical translation, focusing on imaging predictors of phenoconversion from prodromal to clinically overt stages of synucleinopathies, concepts of neural reserve and compensation, imaging correlates of cognitive impairment, and MRI approaches for atypical parkinsonism. Biomarker-informed pharmacological, infusion-based, and surgical strategies, including network-guided and adaptive deep brain stimulation, were discussed as examples of how multimodal biomarkers may inform personalized management. Across all sessions, the need for harmonization, longitudinal validation, and pathology-confirmed outcome measures was consistently emphasized as essential for advancing biomarker qualification in multicentre research and clinical practice

    Addressing Gender in Authenticity and Inclusion at Work: Nuancing Conservation of Resources Theory with Social Role Theory

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    In this paper we elucidate how gender may influence the mechanisms and conditions under which perceived inclusion climate facilitates authenticity at work. We nuance conservation of resources theory with social role theory to argue that perceived inclusion climate acts as a caravan passageway through which authenticity at work can be fostered, yet how inclusion climate relates to authenticity is different for men versus for women. We hypothesize that men will feel more authentic when they perceive their organization to be inclusive because such perceptions enable them to feel unique, whereas women will feel more authentic when in inclusive organizations because such environments foster their belongingness. In a time-lagged study, we find that for women, it is belongingness that is the mediating process, whereas for men, it is both uniqueness and belongingness. We additionally propose, and find, that structural empowerment, as an HRM contextual resource caravan, moderates the relationships between perceived inclusion climate and belongingness/uniqueness for women but not for men. Here, structural empowerment is particularly important for women’s needs for belongingness and uniqueness when they perceive their organization be not very inclusive. Overall, we contribute to workplace inclusion and authenticity literatures by underscoring the need to consider gender differences in more depth

    Rational Design of CdS QDs/CeO2 Nanocube S-Scheme Heterojunctions for Highly Efficient C2H4 Scavenging in Fresh Produce Preservation

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    Effectively eliminating ethylene (C2H4) during postharvest phase and distribution of fruits and vegetables continues to pose a significant technical hurdle. Although S-scheme heterojunctions have shown promise in optimizing charge carrier separation and redox capacity for ethylene degradation, their catalytic efficiency is still limited by insufficient oxygen activation kinetics. Herein, a novel S-scheme heterojunction composed of CdS quantum dots and CeO2 nanocubes was first rationally designed and was innovatively constructed for the first time, leveraging the oxygen-affinitive characteristics of CeO2 and guided by DFT calculations to enhance interfacial charge transfer and oxygen activation. The optimized 10-CdS–CeO2 composite exhibited superior photocatalytic activity under visible light exposure, exhibited a quasi-first-order reaction rate reaching 1.72 min−1, 35 and 297 times higher than CdS and CeO2, respectively. Even under low-intensity illumination (50 mW·cm−2), complete ethylene degradation was observed within 4 min, surpassing all previous literature known to the authors. Mechanistic investigations via in situ irradiated XPS, UPS, PL, TRPL, and ESR confirmed strong interfacial interactions, efficient S-scheme charge separation, and accelerated O2 activation. The findings establish a reliable theoretical and experimental basis for guiding the development of next-generation high-performance photocatalysts for ethylene scavenging, providing a promising strategy for postharvest preservation of fruits and vegetables

    Carbohydrate restriction drives greater perturbations in circulating metabolites than low energy availability in elite male athletes

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    Periods of low energy availability (LEA) are common in elite athletes and typically arise from reduced energy intake, often involving some degree of carbohydrate (CHO) restriction. Whether the metabolic profile created by energy restriction per se is distinct compared to that driven by CHO restriction is unknown. Using untargeted metabolomics, we examined metabolic perturbations linked to CHO restriction and energy restriction in plasma from elite male endurance athletes. In a semi‐randomized controlled trial, athletes (n = 20) completed one of three 5‐day dietary interventions: high energy‐high CHO (HCHO); LEA (energy‐restricted, CHO‐reduced); or low‐CHO, high‐fat (LCHF; energy‐matched, CHO‐restricted). Plasma samples were taken at multiple timepoints pre‐ and post a standardized 25 km race walk protocol. Metabolomic analysis was performed using liquid chromatography–mass spectrometry (LC–MS), with multivariate analysis conducted using RM‐ASCA+ and hierarchical clustering. A total of 5391 metabolic features were detected and 138 metabolites annotated. LCHF induced substantial metabolic perturbations, especially after prolonged exercise, including elevations in fatty acyls, hydroxy acids, dicarboxylic acids and acylcarnitine intermediates, responses not seen under LEA. We conclude that CHO restriction concomitant with a high‐fat load induces a greater metabolic perturbation in selected lipid‐based metabolites than short‐term LEA exposure in elite athletes undergoing prolonged endurance exercise

    Coach perceptions of “playing-up” in youth football

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    Football coaches are often searching for the most appropriate development environment to help every player to achieve their potential. When youth football players show advanced competencies within their own age group (i.e. U9, U10, U11, etc.), they may be permitted to compete in a chronologically older age group – commonly referred to as ‘playing-up’. Despite this approach being regularly used in practice, coach perceptions of playing-up are yet to be empirically evaluated. Therefore, this study used semi-structured interviews with ten academy football coaches from the United Kingdom to examine their perceptions of playing-up on player development. Following thematic analysis, results showed three higher-order themes comprising nine lower-order themes: (a) strengthening communication approaches (i.e. refine terminology used, emphasise communication between coaches and players, and educate key stakeholders), (b) considering support from social agents (i.e. include parents in the process, involve coaches and multidisciplinary staff in decision-making, and promote supportive peer environments), and (c) facilitating individual player development (i.e. challenge technical and tactical skills, reflect on psychosocial impact, and consider physical competencies). These findings highlight how coaches perceive playing-up as a useful holistic player development tool, which could be enhanced through effective key stakeholder communication and support

    Mine waste and soil chemical properties from around the Auchencat Burn mine, Moffat, Scotland

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    This data describes mine waste and soil chemical properties from three transects (< 20 m length) originating from the opening of the Auchencat Burn mine, Moffat, Scotland. Total metal concentrations (nitric acid digestion), exchangeable copper (ammonium acetate extraction), loss-on-ignition (550 degrees C) and pH are included in the dataset (12 samples in total)

    Editorial: A checklist for appraising the reporting and methodological quality of menstrual cycle (ARMQ-MC) phase-based research in sport science

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    Rationale for the ARMQ-MC checklist The recent, welcomed growth in women’s football (i.e., research, participation, investment, coverage, etc.) means that robust data and credible messaging are needed to support the health and performance of women football players (The Football Association [(Citationdate unknown]; Okholm-Kryger et al. Citation2022; Women’s Sport Trust Citation2024; https://digitalhub.fifa.com/m/4e63f61e61a63a93/original/FIFA-Womens-Football-Benchmarking-Report_EN.pdf). Historically, women have been marginalised in football research. Clausen et al. Citation2025) showed that from the 722 studies in elite football, involving 98,777 participants, only 7% were women and from the 104 studies involving women, only four (<4%) provided sufficient information to define menstrual status. Moreover, in many sports and medicine-related academic degrees, women are siloed into a ‘special population’, with female-specific topics such as the menstrual cycle barely covered in the curriculum, if at all. Collectively, this contributes to: (i) a lack of knowledge and high-quality data on female-specific football and sport science topics; (ii) a gap in training of researchers to conduct high-quality studies in this space; and (iii) a low number of reviewers of scientific journals with expertise in these topics. We, as a research community, have an ethical and professional responsibility to uphold high-quality standards, ensuring data integrity and supporting validity of scientific findings. In this editorial, we synthesise existing guidance with disciplinary experience and expertise to facilitate rigorous menstrual cycle phase-based research methodology development and support the clear and transparent reporting of menstrual cycle phase-based studies. In doing so, we ensure that accurate information is reported, therefore safeguarding the quality of evidence to be translated into practice. While these guidelines have been written for Science and Medicine in Football, the developed ARMQ-MC checklist is relevant for all sport science journals. This editorial will be the official guidance for editors and reviewers of Science and Medicine in Football

    Understanding the factors influencing participant engagement and adherence in exercise referral in the City of Manchester

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    Objectives To identify demographic, clinical, socioeconomic and referral-pathway determinants of engagement, early dropout and non-participation in a large metropolitan exercise referral scheme (ERS), and to assess whether machine learning (ML) methods provide additional explanatory value beyond conventional regression. Methods This retrospective cohort study analysed data from 11 909 adults (≥18 years) referred for ERS in Manchester, UK, between 27 January 2022 and 28 February 2025. Outcomes were programme adherence (completion of ≥12 exercise sessions), early dropout and non-participation. Multinomial logistic regression was used to examine predictors of outcomes. ML methods, including Random Forest models and k-means clustering, were applied to assess predictive performance, rank feature importance and identify participant subgroups. Results Of 11 909 referrals, 34.6% completed the programme, 34.2% declined to participate and 8.0% left early. Younger age, higher neighbourhood deprivation and psychosocial referral reasons (eg, loneliness, long covid) were associated with lower completion. Participants referred through outreach/social prescribing pathways were substantially more likely to remain in an ‘intends to participate’ state rather than complete, compared with those referred through clinical pathways. Random Forest models demonstrated good predictive accuracy, with early engagement indicators and deprivation emerging as the strongest predictors. Clustering identified a high-risk subgroup characterised by younger age, higher deprivation and low early attendance. Conclusions Engagement and adherence in ERS were strongly shaped by early engagement, deprivation, age and referral pathways. ML methods identified high-risk subgroups and reinforced the importance of early attendance. Targeted early support and ML-informed risk indicators may improve retention, particularly among younger and more deprived participants

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