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    9700 research outputs found

    Houseless not Homeless

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    This website is designed to help readers from all backgrounds understand the causes and proposed solutions to homelessness. It explores disability as a cause, the lack of mental health funding and also transitional housing and policy change

    German-Jewish Studies: Next Generations

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    As a field, German-Jewish Studies emphasizes the dangers of nationalism, monoculturalism, and ethnocentrism, while making room for multilingual and transnational perspectives with questions surrounding migration, refugees, exile, and precarity. Focusing on the relevance and utility of the field for the twenty-first century, German-Jewish Studies explores why studying and applying German-Jewish history and culture must evolve and be given further attention today. The volume brings together an interdisciplinary range of scholars to reconsider the history of antisemitism—as well as intersections of antisemitism with racism and colonialism—and how connections to German Jews shed light on the continuities, ruptures, anxieties, and possible futures of German-speaking Jews and their legacies.https://cupola.gettysburg.edu/books/1192/thumbnail.jp

    The Affordable Care Act and Women’s Self-Employment in the United States

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    The United States’ Affordable Care Act (ACA) of 2010 improved and expanded availability of non-group health insurance. Previous studies have shown that women in the US workforce value health insurance more highly than men do. Because prior to the ACA self-employed individuals did not have guaranteed access to affordable health insurance coverage, women’s relatively lower rate of self-employment may partly have reflected their greater “job lock” due to employer-based health insurance. This article employs nationally representative survey data for 2009–18 and a quasi-experimental difference-in-difference modeling approach and finds that unmarried women’s probability of self-employment increased by 1.2 percentage points in 2015–18, after the ACA’s expansion of non-group health insurance came into effect. Among women who have never married, overall probability of self-employment increased by 1.2–1.5 percentage points versus trend, and the probability of transitioning into full-time self-employment increased by 0.9 percentage points

    Developmental Basis of Evolutionary Lung Loss in Plethodontid Salamanders

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    One or more members of four living amphibian clades have independently dispensed with pulmonary respiration and lack lungs, but little is known of the developmental basis of lung loss in any taxon. We use morphological, molecular, and experimental approaches to examine the Plethodontidae, a dominant family of salamanders, all of which are lungless as adults. We confirm an early anecdotal report that plethodontids complete early stages of lung morphogenesis: Transient embryonic lung primordia form but regress by apoptosis before hatching. Initiation of pulmonary development coincides with expression of the lung-specification gene Wnt2b in adjacent mesoderm, and the lung rudiment expresses pulmonary markers Nkx2.1 and Sox9. Lung developmental-genetic pathways are at least partially conserved despite the absence of functional adult lungs for at least 25 and possibly exceeding 60 million years. Adult lung loss appears associated with altered expression of signaling molecules that mediate later stages of tracheal and pulmonary development

    Lenses, Focus, and Fluidity: Lessons from Medieval Queer History

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    The Medieval era is sometimes overlooked within the field of Queer and Transgender History, but a recent shift in focus has revealed new discoveries and interpretations. This historiographical analysis posits that in the Middle Ages, gender and sexuality were much more fluid than previously believed

    Criminal Justice Update - August 2022

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    The Criminal Justice Update is a monthly newsletter created by the Adams County Bar Foundation Fellow providing updates in criminal justice policy coming from Pennsylvania\u27s courts and legislature as well as the US Supreme Court. Contents: Updates from PA Governor\u27s Office (no updates this month) Updates from the PA Legislature (no updates this month) Updates from the Courts U.S. Supreme Court: Criminal Law & Procedure (no updates this month) PA Supreme Court: Criminal Law & Procedure PA Superior Court: Criminal Law & Procedur

    Faculty Meeting Minutes - March 3, 2022

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    Minutes of the Gettysburg College Faculty Business Meeting, March 3, 2022

    Faculty Meeting Minutes - March 17, 2022

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    Minutes of the Gettysburg College Faculty Business Meeting, March 17, 2022

    Faculty Meeting Minutes - April 7, 2022

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    Minutes of the Gettysburg College Faculty Business Meeting, April 7, 2022

    Cold Shock Induces a Terminal Investment Reproductive Response in C. elegans

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    Challenges from environmental stressors have a profound impact on many life-history traits of an organism, including reproductive strategy. Examples across multiple taxa have demonstrated that maternal reproductive investment resulting from stress can improve offspring survival; a form of matricidal provisioning when death appears imminent is known as terminal investment. Here we report a reproductive response in the nematode Caenorhabditis elegans upon exposure to acute cold shock at 2 °C, whereby vitellogenic lipid movement from the soma to the germline appears to be massively upregulated at the expense of parental survival. This response is dependent on functional TAX-2; TAX-4 cGMP-gated channels that are part of canonical thermosensory mechanisms in worms and can be prevented in the presence of activated SKN-1/Nrf2, the master stress regulator. Increased maternal provisioning promotes improved embryonic cold shock survival, which is notably suppressed in animals with impaired vitellogenesis. These findings suggest that cold shock in C. elegans triggers terminal investment to promote progeny fitness at the expense of parental survival and may serve as a tractable model for future studies of stress-induced progeny plasticity

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