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Methodology of the joint malaria prevention recommendations of Switzerland, Germany, Belgium, and the Netherlands
No full textTechnology Integration by Teachers Through the Lens of the ICAP Theory of Active Learning
No full textPreterism, Idealism, Historicism, or Futurism? Interpretative Issues of the Apocalypse and Its Reception in Antiquity and Late Antiquity
No full text
Production and Perception Data on the Ongoing Demise of the Neuter Versus Masculine Contrast from Two Italo-Romance Varieties
No full textSex differences in patient-reported outcomes and the association with clinical factors in axial spondyloarthritis patients treated with tumour necrosis factor inhibitors
No full textOBJECTIVES
To investigate sex differences in patient-reported outcome measures (PROMs) among axSpA patients initiating their first TNFi and identify factors contributing to these disparities over the follow-up.
METHODS
Data were included from 15 EuroSpA registries and consisted of axSpA patients initiating their first TNFi, with ≥2 measurements for each analysed PROM (BASDAI and BASFI, scale 0-100) taken at any time point. Linear mixed models were employed to analyse sex differences in PROMs over 24 months and to evaluate how baseline characteristics were related to the observed sex differences.
RESULTS
We analysed 13 102 (38% women) in the BASDAI analyses and 10 623 (38% women) in the BASFI analyses. At follow-up, mean sex differences in BASDAI increased from 4.3 units at baseline (95% CI, 3.5-5.1)-8.0 (7.2-8.8) at 6 months, and in BASFI from 2.2 (1.4-3.1)-4.6 (3.6-5.5), with consistently worse scores in women. Baseline characteristics could not substantially account for the observed sex differences over time; however, the magnitude of the sex differences was reduced by HLA-B27 positivity, longer disease duration, and increased CRP levels, but increased by TNFi initiation in later years and peripheral arthritis.
CONCLUSION
In axSpA patients initiating their first TNFi, baseline sex differences in BASDAI and BASFI increased two-fold after 6 months of treatment and persisted thereafter, with worse scores in women. Several baseline characteristics moderated the sex differences, though none could fully account for them. These findings improve our understanding of sex differences and underscore their importance in axSpA
Gone fishin’: Addressing completeness, accuracy, and representativeness in the search and coding processes of meta-analyses in the organizational sciences
No full textNo research question is compelling enough nor a meta-analytic procedure advanced enough to overcome an ineffectual search or inaccurate coding process. The bulk of attention towards meta-analyses conducted within the organizational sciences has been directed at establishing the types of research questions meta-analyses are best equipped to address and how best to go about analyzing secondary data. However, the meta-analytic process requires rigor and transparency at every step. It is too often the case that the search and coding are non-systematic, resulting in a deficient and/or contaminated dataset and, ultimately, not an accurate reflection of the extant literature. Using the analogy of a fishing trip where fish are available studies and the oceans, lakes, and rivers are the sources of data, we highlight best practices and offer actionable takeaways in conducting and reporting a thorough and representative search and accurate and inclusive coding process for meta-analyses in the organizational sciences
Gaming the system through temporary housing: Real estate intermediaries and the law in short-term rental markets
No full textThis article contributes empirical and conceptual insights to emerging debates on the regulation of short-term rentals (STRs) by delving into the socio-legal foundations of this housing market segment. Drawing on a qualitative study conducted between September 2022 and June 2023 focused on the governance of for-profit temporary housing (i.e., serviced, furnished, interim housing) in Zurich, it examines how real estate intermediaries in the temporary housing business interact with regulations and carve out niches in tight rental markets. Through an approach that understands temporary housing as a socio-legally constructed asset and a profit-maximising rental strategy within deregulated housing markets, the analysis reveals regulatory blind spots through which intermediaries exploit existing legal tools to circumvent or substitute laws governing rent relations and transactions in the housing market. In doing so, they promote tenure flexibilisation, shaping new pathways to rent extraction. The article foregrounds the concept of gaming to understand intermediaries' interactions and use of legal tools to serve their business interests, suggesting that opportunities for gaming the system of rental regulation are central to creating these assets, making temporary housing itself a strategy for driving housing deregulation and semi-formality. To bring the corruption of rent relations into sharper focus, it is necessary to expand and move beyond debates focused on regulating land use categories towards an understanding of the nexus between market and legal practices and their influence on restructuring rent relations
