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Maternal psycho-social risk factors associated with maternal alcohol consumption and Fetal Alcohol Spectrum Disorder: A systematic review
No full textPurpose
Fetal Alcohol Spectrum Disorder (FASD) is a preventable range of neurocognitive disorders associated with the biological mother’s consumption of alcohol during pregnancy. However, on average, 45% of Australian women continue to consume alcohol during pregnancy resulting in a high rate of alcohol-exposed pregnancies and risk of FASD. This level of exposure is higher than the estimated global average of alcohol-exposed pregnancies (9.8%). This systematic literature review aims to identify demographic, health and psycho-social variables associated with alcohol consumption during pregnancy which may lead to FASD.
Methods
Using PRISMA principles, this systematic literature review reports on psycho-social factors which increase the risk of alcohol consumption during pregnancy thereby increasing the risk of FASD.
Results
Fourteen studies were accepted into this review. Studies were conducted across several countries and included a total of 386,067 cases. Seven studies were case-controlled and seven were cross-sectional design. Multiple studies identified the significance of prior mental illness, anxiety, depression, exposure to abuse and/or domestic violence and alcohol consumption behaviours of partners and family members as strong predictors of risky alcohol consumption during pregnancy and therefore associated risk of FASD.
Conclusion
Clinical services may be able to use the evidence-based findings from this review to improve assessment and treatment services for vulnerable women to reduce alcohol-exposed pregnancies
Adversarial network with multiple classifiers for open set domain adaptation
No full textDomain adaptation aims to transfer knowledge from a domain with adequate labeled samples to a domain with scarce labeled samples. Prior research has introduced various open set domain adaptation settings in the literature to extend the applications of domain adaptation methods in real-world scenarios. This paper focuses on the type of open set domain adaptation setting where the target domain has both private (‘unknown classes’) label space and the shared (‘known classes’) label space. However, the source domain only has the ‘known classes’ label space. Prevalent distribution-matching domain adaptation methods are inadequate in such a setting that demands adaptation from a smaller source domain to a larger and diverse target domain with more classes. For addressing this specific open set domain adaptation setting, prior research introduces a domain adversarial model that uses a fixed threshold for distinguishing known from unknown target samples and lacks at handling negative transfers. We extend their adversarial model and propose a novel adversarial domain adaptation model with multiple auxiliary classifiers. The proposed multi-classifier structure introduces a weighting module that evaluates distinctive domain characteristics for assigning the target samples with weights which are more representative to whether they are likely to belong to the known and unknown classes to encourage positive transfers during adversarial training and simultaneously reduces the domain gap between the shared classes of the source and target domains. A thorough experimental investigation shows that our proposed method outperforms existing domain adaptation methods on a number of domain adaptation datasets
Phylogenetic structure of alien plant species pools from European donor habitats
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Many plant species native to Europe have naturalized worldwide. We tested whether the phylogenetic structure of the species pools of European habitats is related to the proportion of species from each habitat that has naturalized outside Europe (habitat’s donor role) and whether the donated species are more phylogenetically related to each other than expected by chance.
Location
Europe (native range), the rest of the world (invaded range).
Time period
Last c. 100 years.
Major taxa studied
Angiospermae.
Methods
We selected 33 habitats in Europe and analysed their species pools, including 9,636 plant species, of which 2,293 have naturalized outside Europe. We assessed the phylogenetic structure of each habitat as the difference between the observed and expected mean pairwise phylogenetic distance (MPD) for (a) the whole species pool and (b) subgroups of species that have naturalized outside Europe and those that have not. We used generalized linear models to test for the effects of the phylogenetic structure and the level of human influence on the habitat’s donor role.
Results
Habitats strongly to moderately influenced by humans often showed phylogenetically clustered species pools. Within the clustered species pools, those species that have naturalized outside Europe showed a random phylogenetic structure. Species pools of less human-influenced natural habitats varied from phylogenetically clustered to overdispersed, with donated naturalized species also often showing random patterns within the species pools. Donor roles in both habitat groups increased with increasing MPD within habitats.
Main conclusions
European human-influenced habitats donate closely related species that often naturalize in disturbed habitats outside their native range. Natural habitats donate species from different lineages with various ecological strategies that allow them to succeed in different habitats in the invaded range. However, the naturalized species donated by most European habitats are phylogenetically random subsets of their species pools
Climate influences productivity but not breeding density of wedge‐tailed eagles Aquila audax in arid and mesic Western Australia
No full textLong-term studies are required to reveal responses by long-lived, top-order predator populations to ongoing seasonal fluctuations. However, such investigations are rare in the Australian context. Between 2009 and 2019, the breeding density and productivity of an arid and a mesic wedge-tailed eagle Aquila audax population, each occupying an area of 2800 km2, were compared (11–98 pairs monitored annually). Breeding pairs spaced themselves evenly in both study areas, with no significant difference between the average arid zone nearest-neighbour distance of 5.32 ± 1.98 km (n = 44) and that determined for the mesic zone (4.88 ± 2.32 km, n = 54). This similarity in spacing suggests a maximum average density is tolerated by these territorial raptors. By contrast, annual breeding success (proportion of pairs fledging young) and productivity (fledged young per pair) differed significantly between the two populations, with rainfall (but not temperature) influencing reproduction. In the arid zone, the proportion of successful pairs per occupied breeding home range was consistently low each year (mean = 12 ± 7% fledged broods per pair, range 0–26%) and positively correlated with annual rainfall. In the mesic zone, it was consistently high each year (mean = 69 ± 9%, range 57–91%) and not significantly correlated with annual rainfall. Overall productivity figures showed similar differences, with 0.13 and 0.77 fledglings per pair per year for arid (n = 9 years) and mesic (n = 11 years) eagles, respectively. Such low arid zone productivity, the lowest ever recorded for the species, could have long-term implications in the face of the increased frequency of extreme weather events. That breeding density can be independent of climatic factors provides new insight into the way a large Aquila species integrates with Australia’s predominantly arid environment. This study provides an important baseline data set for continued research on long-term occupancy and productivity trends
Safety and efficacy of dimethyl fumarate in ALS: randomised controlled study
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Neuroinflammation is an important pathogenic mechanism in amyotrophic lateral sclerosis (ALS), with regulatory T cells (Tregs) mediating a slower rate of disease progression. Dimethyl fumarate enhances Treg levels and suppresses pro-inflammatory T cells. The present study assessed the safety and efficacy of dimethyl fumarate in ALS.
Methods
Phase-2, double-blind, placebo-controlled randomised clinical trial recruited participants from May 1, 2018 to September 25, 2019, across six Australian sites. Participants were randomised (2:1 ratio) to dimethyl fumarate (480 mg/day) or matching placebo, completing visits at screening, baseline, weeks 12, 24 and 36. The primary efficacy endpoint was a change in Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R) at week 36. Secondary outcome measures included survival, neurophysiological index (NI), respiratory function, urinary neurotrophin-receptor p75 and quality of life.
Results
A total of 107 participants were randomised to dimethyl fumarate (n = 72) or placebo (n = 35). ALSFRS-R score was not significantly different at week 36 (−1.12 [−3.75 to 1.52, p = 0.41]). Dimethyl fumarate was associated with a reduced NI decline week 36 (differences in the least-squares mean: (0.84 [−0.51 to 2.22, p = 0.22]). There were no significant differences in other secondary outcome measures. Safety profiles were comparable between groups.
Interpretation
Dimethyl fumarate, in combination with riluzole, was safe and well-tolerated in ALS. There was no significant improvement in the primary endpoint. The trial provides class I evidence for safety and lack of efficacy of dimethyl fumarate in ALS
Grounded Theory: A guide for a new generation of researchers
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Grounded Theory (GT) has grown and developed into several strands making its application all the more problematic, argumentative and remaining potentially as a research methodology to avoid when it comes to doctoral research, early-career research. Thus, the purpose of this paper is to revisit GT as a general approach and present an evolved and more considered step-by-step guide to conduct research using this methodology. A leadership development context is applied in this paper to examine how this methodology could work for a new generation of researchers, i.e., new to doctoral research or an early career researcher.
Background
Since its academic inception in the seminal text in 1967 (Glaser & Strauss, 1967), GT has emerged and developed to become a popular choice for researchers contemplating qualitative data approaches amongst a variety of subject backgrounds. However, the divergent development and criticized approaches within GT families can lead researchers to avoid such a research methodology. This can especially be the case within doctoral research or other early-career research. Indeed, a specific/explicit GT guideline or framework to assist doctoral students in conducting GT research does not currently exist.
Methodology
There is a general review of GT approaches followed by theoretical development of a framework and an applied doctoral example.
Contribution
The three evolved methods in GT research and the developed supporting author-designed three-phase research framework will contribute to two aspects. Firstly, the step-by-step guideline can reduce the sense of confusion within an area where criticisms and conflicting approaches exist. This will hopefully assist the next generation of GT researchers in conducting their research through detailed processes and applications. Secondly, there is arguably a need for more GT applications and evolvements to further enrich the body of knowledge that exists in this area and further support a diversity of subject research.
Findings
The authors outline numerous differences and similarities within divergent GT practices. By integrating Glaser’s four core principles and three evolved methods, the authors design a three-phase research framework that presents a transparent step-by-step guide. This framework attempts to mitigate criticisms within GT approaches whilst maintaining clarity, flexibility, depth, and rigour within a study.
Recommendations for Practitioners
Three GT evolvements (the two-step literature review method, two-step open-coding method, and two-step theory-constitute method) provides greater clarity within a rigorous author-designed three-phase research framework that demonstrates a transparent step-by-step guide. These techniques can encourage a new generation of GT researcher through confident and structured analytical techniques.
Recommendation for Researchers
We hope the presented framework and concise view of GT in action will inspire other doctoral students and new GT researchers to conduct GT research following an evolved GT framework.
Impact on Society
The debates and innovations around GT, like in this paper, are needed within a methodological society to keep the area contemporary and constantly evolving.
Future Research
The framework presented will need further testing beyond the parameters set out here. We hope future research can adopt the evolved GT techniques and procedures to enforce research quality overall and inspire further GT methodological developments
Does sustainability reporting promote university ranking? Australian and New Zealand evidence
No full textPurpose
This study aims to investigate the relationship between university rankings and sustainability reporting among Australia and New Zealand universities. Even though sustainability reporting is an established area of investigation, prior research has paid inadequate attention to the nexus of university ranking and sustainability reporting.
Design/methodology/approach
This study covers 46 Australian and New Zealand universities and uses a data set, which includes sustainability reports and disclosures from four reporting channels including university websites, and university archives, between 2005 and 2018. Ordinary least squares regression was used with Pearson and Spearman’s rank correlations to investigate the likelihood of multi-collinearity and the paper also calculated the variance inflation factor values. Finally, this study uses the generalized method of moments approach to test for endogeneity.
Findings
The findings suggest that sustainability reporting is significantly and positively associated with university ranking and confirm that the four reporting channels play a vital role when communicating with university stakeholders. Further, this paper documents that sustainability reporting through websites, in addition to the annual report and a separate environment report have a positive impact on the university ranking systems.
Originality/value
This paper contributes to extant knowledge on the link between university rankings and university sustainability reporting which is considered a vital communication vehicle to meet the expectation of the stakeholder in relevance with the university rankings
Real time surveillance for low resolution and limited data scenarios: An image set classification approach
No full textThis paper proposes a novel image set classification technique based on the concept of linear regression. Unlike most other approaches, the proposed technique does not require any training. We represent the gallery image sets as subspaces in a high dimensional space. Class specific gallery subspaces are used to estimate regression models for each image in the test image set. Images of the test set are then projected onto the gallery subspaces. The residuals, calculated using the Euclidean distance between the original and the projected test images, are used as the distance metric. Three different strategies are devised to decide on the final class of the test image set. We extensively evaluated the proposed technique using both low resolution and noisy images and with less gallery data to assess the suitability of our technique for the tasks of surveillance and video-based face recognition. The experiments show that the proposed technique achieves superior classification accuracy and has a faster execution time compared with existing techniques, especially under the challenging conditions of low resolution and a limited amount of gallery and test data
Mediterranean fruit fly genes exhibit different expression patterns between heat and cold treatments
No full textInvasive Tephritid fruit flies are a global threat to both agriculture and horticulture industries. Biosecurity has played a critical role in reducing their damage but becomes more and more challenging after several key chemical pesticides were banned or withdrawn for health or environmental reasons. This has led to non-chemical approaches including heat and cold treatments being broadly utilized to get rid of fruit fly infestation. However, the molecular mechanisms to kill the flies underlying these stressors are not clear yet. This knowledge will certainly help refine current post-harvest treatment strategies and develop more efficient, cost-effective and environmentally friendly approaches for fruit fly management. Previously, the molecular response of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann) to heat was examined thoroughly, in which 31 key genes were identified with significant changes in expression levels and their high-resolution expression timeline was constructed across 11 timepoints. However, whether these candidate genes respond to cold in the same way was unknown. Here, a temperature bioassay was conducted and the expression profiles of these genes were investigated across the same 11 timepoints using cold treatment. The results showed that most of candidate genes exhibited divergent expression profiles compared to heat treatment, suggesting that the fly molecular response to cold may be different from those to heat. This study provides new knowledge of Tephritid fruit fly response to cold at a molecular level, which could aid in improving current fruit fly management and facilitate the development of new strategies to control this serious horticultural insect pest
Significance of forms and foci of metacognitive regulation in collaborative science learning of less and more successful outcome groups in diverse contexts
Get PDFThis study investigated how metacognitive regulation (MR), especially its forms and foci, was manifested in less and more successful outcome groups’ collaborative science learning in diverse learning contexts. Whilst previous research has shown that different forms and foci of MR exist in collaborative learning, their role in groups’ learning outcomes remains unexplored. Drawing conclusions from different studies has been difficult because these have used different conceptualisations and analytic methods. In the present study, the learning processes of less and more successful outcome groups from three diverse collaborative science learning contexts were scrutinised. The contexts differed in academic level, disciplinary subject, and national culture. The same theory-based conceptualisations, coding systems, coders, and analyses were used across contexts. In addition, the tasks studied were designed using the same guiding principles. Transcribed video and audio recordings of the groups’ verbal interactions for two distinct interaction segments from these tasks formed the basis of the analyses. Manifestation of forms and foci of MR were quantitatively and qualitatively illustrated in each context. The main findings show that the manifestation of MR of less and more successful outcome groups demonstrated similarities and differences in the three different learning contexts. This study contributes to a contextualised understanding of MR in collaborative science learning, and highlights the importance of using similar, rigorous analytical tools across diverse contexts