Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences
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Logarithmic bacterial gradient chip for analyzing the effects of dietary restriction on C. elegans growth
No full textC. elegans is a commonly used model organism for studying the basic mechanisms of lifespan extension by dietary restriction (DR). Progress has been limited, however, by the lack of an automated system for quantitative analysis of this effect of bacterial diet. In this work, multifunctional logarithmic gradient customizing microfluidic device, which takes advantage of hydrodynamics, was developed to long-term maintain worm culture on the chip with parallel live imaging and generate logarithmic concentration gradient of bacteria. We successfully employed this platform to investigate the longevity and stress response of the worms in response to various concentrations of bacterial food. The results indicated that the lifespan extension of the worms was induced by DR when bacteria density was 108 cells mL(-1) and further dilutions would reduce the lifespan, which proposed a new dietary restriction regime in C. elegans. In addition, imaging analysis showed that DR regulated the subcellular localization DAF-16 in a way different from starvation that reduced lifespan of the worms. The platform allows not only horizontal studies of C. elegans in response to various environments over a wide range of concentrations, but also multiparameter evaluation of longevity in the worms with high temporal resolution, providing clues to better understand the aging process and help age-related drug screen. (C) 2017 Elsevier B.V. All rights reserved
Co-metabolic removal of ciprofloxacin under condition of interaction between microbes and Fe3O4
No full textPotential of effluents from biological hydrogen production process to improve ciprofloxacin (CIP) removal was investigated using ciprofloxacin-degrading enrichments in the presence of Fe3O4 nanoparticles. Effluent addition clearly promoted CIP removal, which was 61%, 38% and 16% higher than those in the enrichments amended with fecal sewage, biogas digestate and water, respectively. Experiments of sterilization and organic components of effluents indicated that the organic substances served as co-metabolic substrate to facilitate CIP removal, where ethanol was the preferred co-metabolic substrate. Although the effluent addition changed the bacterial community composition which corresponded to the changes in the relative abundances of dominant genera in the enrichments, CIP removal performance remained unchanged. The increased Fe (II) concentrations indicated that there might be a positive relationship of CIP removal with the microbial reduction of Fe (III) to Fe (II) in Fe3O4 in the effluents-amended enrichments. It was proposed that the organic substances in the effluents might serve as the co-metabolic substrate to promote CIP removal by CIP-degrading and Fe (III)-reducing bacteria
论文收录引证检索报告与科技查新服务
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<strong><span style="font-size:16px;">各位同事、同学：</span></strong></p>
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<strong><span style="font-size:16px;"> 如果您需要收录引证检索服务，至少提前2天提交申请。</span></strong></p>
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<strong><span style="font-size:16px;"> </span></strong><strong><span style="font-size: 16px;">不是申报杰青优青</span></strong><strong><span style="font-size: 16px;">，请下载附件《</span></strong>通用（非杰青优青申报使用）——姓名——中科院青岛生物能源所图书馆论文收录引用检索申请表（2018）<strong><span style="font-size: 16px;">》；</span></strong><strong><span style="font-size:16px;">申报杰青优青，请下载附件《</span></strong>杰青优青申报专用——XXX-中科院青岛生物能源所图书馆论文收录引用检索申请表（2018年）<strong><span style="font-size:16px;">》。</span></strong><strong><span style="font-size: 16px;"> 根据下载的附件，结合自己申报细节要求，逐项修改和设计您需要的内容，不得有误。申请表电子版交图书馆完成申请。</span></strong></p>
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<strong><span style="font-size:16px;"> 特别提醒当事人（被检索人）要明确以下几个关键问题，否则无法完成您需要的检索报告：</span></strong><strong><span style="font-size:16px;"> </span></strong></p>
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1、收录——具体需要检索哪几个数据库SCI、EI、CSCD中的一个或几个收录？</p>
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2、引用——需要SCI、CSCD数据库中的一个或两个引用？其中，（1）他引排除检索论文（被引论文）的“本人”引用？（2）还是排除检索论文（被引论文）所有作者的引用？</p>
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3、JCR——是否需要分区？期刊影响因子具体时间（一般是论文发表当年的）？</p>
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4、提交论文信息——（1）如果区分通讯作者、唯一通讯作者、非唯一通讯作者、第一作者、唯一第一作者、非唯一第一作者、非通讯且非第一作者，提供的论文也必须对应分类按由近及远的出版时间顺序排列。（2）如果需要他引排除论文所有作者，务必给出每篇论文所有作者的全拼（正常顺序，如张三丰，提供“zhang Sanfeng”）。</p>
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确定以上问题后，根据提供的报告模板制作自己需要的报告结果（具体参见附件9《各类论文收录引证检索报告模板》）。</p>
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<strong><span style="font-size:16px;"> </span></strong></p>
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<strong><span style="font-size:16px;"> 检索报告完成后，图书馆会通知有关事宜。关键问题明示：</span></strong></p>
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<span style="font-size:14px;"><strong>一、提前申请及时办理</strong></span></p>
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<span style="font-size:14px;"> 由于收录引证检索比较耗时，且常出现扎堆排队现象，甚至耽误部分同志大事。如您有收录引证检索报告需求，须提前至少2天提交申请，以免影响您的计划。</span></p>
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<span style="font-size:14px;"><strong>二、根据需要确定盖章途径</strong></span></p>
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<strong><span style="font-size:14px;"> 1、具有法律效力的盖章及收费，主要有3家：</span></strong></p>
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<span style="font-size: 14px;">（1）教育部查新工作站盖章（效力等同于中科院文献情报中心），100元/份报告；</span></p>
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<span style="font-size:14px;">（2）中科院文献情报中心盖章，按收录、引用量计费，一般千元左右，高的可几千元，有的超过一万元。计算价格规则见附件《青岛生物能源所期刊论文收录引证报告多途径效益比较分析》；</span></p>
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<span style="font-size: 14px;">（3）青岛情报所盖章，免费（路途遥远复杂，不推荐）。</span></p>
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<strong><span style="font-size:14px;"> 2、本所盖章，免费，没有法律效力，仅在一定程度上起到证明作用。</span></strong></p>
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<span style="font-size:14px;"> 请大家根据申报要求决定由盖章机构选择。</span></p>
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<span style="font-size:14px;"><strong>三、服务费用</strong></span></p>
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<span style="font-size:14px;"> 1、盖章费：海大</span><span style="font-size: 14px;">100元盖章费由团队负责人指定课题经费支付，年底图书馆统一办理；</span><span style="font-size: 14px;">中科院文献情报中心盖章需要及时付款。</span></p>
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<span style="font-size: 14px;"> 2、专家咨询费：</span><span style="font-size: 14px;">委托其他单位具有资质的专家<strong>利用业余时间</strong>提供<strong>高质量快速服务</strong>，象征性收取专家咨询费（远远低于院文献情报中心</span><span style="font-size: 14px;">和海大</span><span style="font-size: 14px;">收费）。提供专家身份证号、</span><span style="font-size: 14px;">单位名称、</span><span style="font-size: 14px;">开户行、账号信息，由检索报告申请人从课题支付，团队秘书具体办理。</span></p>
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<span style="font-size:14px;"><strong>四、自助服务</strong></span></p>
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<span style="font-size:14px;"> 为便于大家自我进行论文收录引证检索和撰写规范的收录引证检索报告，图书馆组织了针对性培训，课件见附件。</span></p>
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<span style="font-size: 14px;"> 本所图书馆尚无科技查新服务措施，但可以协调权威机构服务</span><span style="font-size: 14px;">。</span></p>
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<span style="font-size:14px;"> 有任何问题，请及时与图书馆联系15153237828，80662648。谢谢！</span></p>
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<span style="font-size:14px;"> </span></p>
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<span style="font-size:14px;"> 规划战略与信息中心<br />
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<span> 2018年3月4日</span></span></p
Fabrication of mesoporous Co3O4 oxides by acid treatment and their catalytic performances for toluene oxidation,
No full textConsidering the harmful effects of volatile organic compounds (VOCs) on the atmosphere and public health, the
search for proper catalytic materials for the effective catalytic elimination of VOCs remains one of the most
pressing issues in the environmental field. In this study, a series of mesoporous Co3O4-n (n= 0.00, 0.0001, 0.01,
0.05, 0.10, 1.00, representing the concentration of HNO3 aqueous solution) catalysts were fabricated by the acid
treatment of Co3O4 that was previously prepared via a hydroxycarbonate precipitation method (Co3O4-P). The
catalytic performances of the prepared catalysts were evaluated for the model reaction of toluene oxidation. An
obvious enhancement of catalytic activity in the reaction was achieved over the acid-treated Co3O4 catalysts
using lower HNO3 concentrations, with Co3O4-0.01 exhibiting the optimum catalytic activity (T90 =225 °C,
15 °C lower than that of Co3O4-P), excellent catalytic durability under dry conditions and a high regeneration
capability under humid conditions. Benefitting from the dilute acid treatment, the Co3O4-n (n =0.01, 0.05,
0.10) catalysts presented higher specific surface areas, more weak acidic sites and higher abundances of surface
Co2+ and Oads species, which were regarded as the key factors responsible for their enhanced catalytic activities
IncoPat中文检索世界专利平台使用方法与技巧集锦
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<span id="aui_3_2_0_1467" style="FONT-SIZE: 16px"> 无论基础研究，还是应用研究，对领域专利信息及时跟进和系统分析是研发方向确定，优化和技术权利保护的重要手段。</span></p>
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<span style="FONT-SIZE: 16px"> IncoPat是合享汇智信息科技集团研发的专利信息服务平台，用<strong>中文</strong>搞定全球112个国家和地区的1.2亿件专利信息且48小时动态更新，平台界面友好，检索便捷。该平台采用智能语义检索，精准聚焦目标专利，通过价值度智能排序，可以快速发现高价值专利信息；还具有定制监测功能，让您实时了解行业技术最新动态，并通过全面细致的专利分析，从多个角度呈现技术布局情况。</span></p>
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<span style="FONT-SIZE: 16px"> 图书馆经过沟通，开通了该数据库的试用：5月30日-6月30日。</span></p
Comparative transcriptome analysis of duckweed (Landoltia punctata) in response to cadmium provides insights into molecular mechanisms underlying hyperaccumulation
No full textCadmium (Cd) is a detrimental environmental pollutant. Duckweeds have been considered promising candidates for Cd phytoremediation. Although many physiological studies have been conducted, the molecular mechanisms underlying Cd hyperaccumulation in duckweeds are largely unknown. In this study, clone 6001 of Landoltia punctata, which showed high Cd tolerance, was obtained by large-scale screening of over 200 duckweed clones. Subsequently, its growth, Cd flux, Cd accumulation, and Cd distribution characteristics were investigated. To further explore the global molecular mechanism, a comprehensive transcriptome analysis was performed. For RNA-Seq, samples were treated with 20 mu M CdCl2 for 0,1, 3, and 6 days. In total, 9,461, 9,847, and 9615 differentially expressed unigenes (DEGs) were discovered between Cd-treated and control (0 day) samples. DEG clustering and enrichment analysis identified several biological processes for coping with Cd stress. Genes involved in DNA repair acted as an early response to Cd, while RNA and protein metabolism would be likely to respond as well. Furthermore, the carbohydrate metabolic flux tended to be modulated in response to Cd stress, and upregulated genes involved in sulfur and ROS metabolism might cause high Cd tolerance. Vacuolar sequestration most likely played an important role in Cd detoxification in L punctata 6001. These novel findings provided important clues for molecular assisted screening and breeding of Cd hyperaccumulating cultivars for phytoremediation. (C) 2017 Elsevier Ltd. All rights reserved
如何利用中科院科技论文预印本系统及时抢占成果首发权并快速提高影响力
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<span style="font-size:18px;"> 预印本（Preprint）是指科研工作者的研究成果在正式出版物上发表前，而出于和同行交流目的自愿在学术会议上或通过互联网发布的科研论文、科技报告等文章。</span></div>
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<span style="font-size:18px;"> 一篇论文从投稿到发表往往要经过数月甚至一年，部分科学领域发展十分迅猛，需要更便捷的科学交流形式；更重要的是科研人员通过预印本形式发表成果，具有排他性：成果的首发权！</span></div>
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<span style="font-size:18px;"> ChinaXiv（<a href="http://www.chinaxiv.org/">中科院科技论文预发布</a><a href="http://www.chinaxiv.org/">平台</a>）是中科院科学传播局组织实施的国内首个按国际通行模式规范运营的预发布平台，中科院文献情报中心联合相关研究所和相关科技期刊倾力打造，该平台2016年8月上线以来，已经发布了论文10000多篇。</span></div>
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<span style="font-size:18px;"> 欢迎积极利用预发布平台抢占首发权，快速提升个人成果引用成为热点论文！</span></p>
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基于专利分析的藻油DHA技术发展研究
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<span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei"; font-size: 16px; text-align: justify;">藻油DHA作为新一代功能食品药物保健因子,正成为全球科研和产业关注的热点。以DHA领域的专利为研究对象,从菌种选育、发酵培养、收集提取、富集纯化、精制、改性及衍生化的角度,全面梳理了藻油DHA生产链专利技术的趋势和分布,识别了技术发展动向和技术空白点,发现DHA的生产技术向着提高DHA的纯度、稳定性、产量的方向发展,产品形式日益多样化,并向日常消费品方向扩展。剖析了国内外主要机构在华专利的技术特点,国外机构在华专利已覆盖藻油DHA生产的全链条和DHA的产品领域,而国内企业DHA专利申请的时间较晚且专利数量较少,主要集中于藻油DHA的生产技术和DHA在食品中的应用。最后,提出了工艺技术研发、专利战略布局、丰富产品形式方面的建议。 </span></p